H. Taguchi

发表

Catalytic antibodies to HIV: physiological role and potential clinical utility.

Yasuhiro Nishiyama, Hiroaki Taguchi, Y. Nishiyama, 2008, Autoimmunity reviews.

Naturally Occurring Proteolytic Antibodies

A. Edmundson, Y. Nishiyama, C. Hanson, 2004, Journal of Biological Chemistry.

Crystal structure of 6-deoxy-α-l-psicofuranose

H. Taguchi, T. Ishii, A. Yoshihara, 2015, Acta crystallographica. Section E, Crystallographic communications.

Catalytic antibodies to amyloid beta peptide in defense against Alzheimer disease.

Yasuhiro Nishiyama, Paul Szabo, Hiroaki Taguchi, 2008, Autoimmunity reviews.

Phosphonate Ester Probes for Proteolytic Antibodies*

Y. X. Zhou, Y. Nishiyama, S. George, 2001, The Journal of Biological Chemistry.

Exceptional Amyloid β Peptide Hydrolyzing Activity of Nonphysiological Immunoglobulin Variable Domain Scaffolds*

Y. Nishiyama, Gopal Sapparapu, S. Paul, 2008, Journal of Biological Chemistry.

Vasoactive intestinal peptide binding autoantibodies in autoimmune humans and mice

F. Arnett, D. Cavill, T. Gordon, 2002, Peptides.

A new algorithm to convert a normal antibody into the corresponding catalytic antibody

H. Taguchi, T. Uda, E. Hifumi, 2020, Science Advances.

New technologies to introduce a catalytic function into antibodies: A unique human catalytic antibody light chain showing degradation of β‐amyloid molecule along with the peptidase activity

H. Taguchi, E. Toorisaka, T. Uda, 2019, FASEB bioAdvances.

Theory of proteolytic antibody occurrence.

Y. Nishiyama, S. Paul, S. Planque, 2006, Immunology letters.

Antibody light chain-catalyzed hydrolysis of a hepatitis C virus peptide.

Z. Keck, S. Foung, Y. Nishiyama, 2004, Bioorganic & medicinal chemistry letters.

Toward Selective Covalent Inactivation of Pathogenic Antibodies

Y. Nishiyama, S. Paul, S. Planque, 2004, Journal of Biological Chemistry.

Specific HIV gp120-cleaving Antibodies Induced by Covalently Reactive Analog of gp120*

Y. Nishiyama, C. Hanson, S. Paul, 2003, Journal of Biological Chemistry.

α-D,l-Sorbose

H. Taguchi, T. Ishii, A. Yoshihara, 2018 .

Naturally occurring catalytic antibodies: evidence for preferred development of the catalytic function in IgA class antibodies

R. Kyle, Y. Nishiyama, S. Paul, 2007, Molecular biotechnology.

Characterization of Toll-like Receptor 7 / 8 Agonist Amino Acid for Antigen-Adjuvant Conjugation Co-delivery System

Ryota Uchida, K. Nishida, Y. Fujita, 2019 .

A new catalytic site functioning in antigen cleavage by H34 catalytic antibody light chain

H. Taguchi, T. Uda, E. Hifumi, 2022, Scientific Reports.

Effects of Physical Damage in the Intermediate Phase on the Progression of Amyloid bFibrillization.

H. Sugiyama, Masayuki Endo, Kumi Hidaka, 2019, Chemistry, an Asian journal.

Muscle-Directed Anti-Aβ Single-Chain Antibody Delivery via AAV1 Reduces Cerebral Aβ Load in an Alzheimer’s Disease Mouse Model

S. Ponnazhagan, Robert Lalonde, A. Pattanayak, 2013, Journal of Molecular Neuroscience.

Practical synthesis of polyhalomethyllithium carbonyl adducts

Hisashi Yamamoto, H. Taguchi, H. Nozaki, 1974 .

Amino acids and peptides. LII. Design and synthesis of opioid mimetics containing a pyrazinone ring and examination of their opioid receptor binding activity.

Y. Okada, S. Bryant, L. Lazarus, 1998, Chemical & pharmaceutical bulletin.

Synthesis and electronic, photophysical, and electrochemical properties of a series of thienylcarbazoles.

Shin-ichiro Kato, A. Kobayashi, S. Tobita, 2012, The Journal of organic chemistry.

A facile route to -muscone

Hisashi Yamamoto, H. Taguchi, H. Nozaki, 1976 .

.beta.-Oxido carbenoids as synthetic intermediates. Facile ring enlargement reaction

Hisashi Yamamoto, H. Taguchi, H. Nozaki, 1974 .

A Facile Ring Enlargement Reaction via β-Oxido Carbenoid

Hisashi Yamamoto, H. Taguchi, H. Nozaki, 1977 .

Simple approach towards the synthesis of 5-methyl-2-hydroxypyrazine derivatives from dipeptidyl chloromethyl ketones

Y. Okada, Y. Nishiyama, H. Taguchi, 1994 .

Reactions of β-hydroxy sulfoxides with N-bromosuccinimide

Hisashi Yamamoto, H. Taguchi, H. Nozaki, 1973 .

A new synthesis of olefins from β-hydhoxy carboxylic acids

S. Hara, Hisashi Yamamoto, H. Taguchi, 1975 .

New synthesis of .alpha.,.beta.-unsaturated carboxylic esters

K. Oshima, H. Taguchi, K. Yamamoto, 1974 .

A New Synthesis of α,β-Unsaturated Carboxylic Esters. The Condensation of Ethyl Lithiotrimethylsilylacetate with Carbonyl Compounds

Hisashi Yamamoto, H. Taguchi, H. Nozaki, 1974 .

A new synthesis of α,β-unsaturated aldehydes including (e)2-methyl-2-alkenal

Hisashi Yamamoto, H. Taguchi, Shin‐ya Tanaka, 1973 .

High-Modulus Poly(ethylene terephthalate)/Expandable Fluorine Mica Nanocomposites with a Novel Reactive Compatibilizer

S. Nishimura, A. Yamaguchi, H. Tateyama, 2002 .

Current status of multiple antigen-presenting peptide vaccine systems: Application of organic and inorganic nanoparticles

Y. Fujita, H. Taguchi, 2011, Chemistry Central journal.

Antibodies to the superantigenic site of HIV-1 gp120: hydrolytic and binding activities of the light chain subunit.

Y. Nishiyama, S. Paul, S. Planque, 2007, Molecular immunology.

Nanoparticle-Based Peptide Vaccines

Y. Fujita, H. Taguchi, 2016, Micro and Nanotechnology in Vaccine Development.

VIPase autoantibodies in Fas‐defective mice and patients with autoimmune disease

Y. Nishiyama, S. Paul, S. Planque, 2003, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Total synthesis of optically active deoxyaspergillic acid from dipeptidyl aldehyde

Y. Okada, H. Taguchi, T. Yokoi, 1996 .

Overview and outlook of Toll-like receptor ligand-antigen conjugate vaccines.

Y. Fujita, H. Taguchi, 2012, Therapeutic delivery.

Specific Amyloid β Clearance by a Catalytic Antibody Construct*

E. Sigurdsson, R. Friedland, Y. Nishiyama, 2015, The Journal of Biological Chemistry.

Antibodies as defensive enzymes

Y. Nishiyama, M. Weksler, C. Hanson, 2005, Springer Seminars in Immunopathology.

Ontogeny of Proteolytic Immunity

A. Edmundson, Xiao-tong Song, B. Poindexter, 2004, Journal of Biological Chemistry.

Autoantibody-catalyzed Hydrolysis of Amyloid β Peptide*

J. Symerský, R. Friedland, A. Edmundson, 2008, Journal of Biological Chemistry.

Characterization of gp120 hydrolysis by IgA antibodies from humans without HIV infection.

H. Sheppard, R. Kyle, M. Escobar, 2007, AIDS research and human retroviruses.

Broadly distributed nucleophilic reactivity of proteins coordinated with specific ligand binding activity

Y. Nishiyama, C. Hanson, S. Paul, 2005, Journal of molecular recognition : JMR.

Amino Acids and Peptides. Part 48. 1 Studies on the Structure of an Unexpected Reaction Product from Dipeptidyl Chloromethyl Ketone during Acid Hydrolysis 2

Y. Okada, Y. Nishiyama, K. Igarashi, 1997 .

Unexpected reaction of dipeptidyl chloromethyl ketone during acid hydrolysis

Y. Okada, Y. Nishiyama, F. Kasuya, 1994 .

Amino acids and peptides. XXXVI. Synthesis of enkephalin chloromethyl ketone and evaluation of its inhibitory activity against endopeptidase 22.19.

A. Camargo, Y. Okada, Y. Nishiyama, 1993, Chemical & pharmaceutical bulletin.

Amino Acids and Peptides. Part 48. Studies on the Structure of an Unexpected Reaction Product from Dipeptidyl Chloromethyl Ketone During Acid Hydrolysis.

Y. Okada, Y. Nishiyama, K. Igarashi, 1997 .

Amino Acids and Peptides. XLVII. Facile Synthesis of Flavacol, Deoxymuta-aspergillic Acid and Optically Active Deoxyaspergillic Acid from Dipeptidyl Aldehydes

Y. Okada, H. Taguchi, T. Yokoi, 1996 .

Amino Acids and Peptides. XLI. 1:2 Facile Synthesis of 5-Methyl-2(1H)- pyrazinone Derivatives from Dipeptidyl Chloromethyl Ketones 3

Y. Okada, H. Taguchi, T. Yokoi, 1995 .

Amino Acids and Peptides. Part 47. Facile Synthesis of Flavacol, Deoxymuta‐aspergillic Acid and Optically Active Deoxyaspergillic Acid from Dipeptidyl Aldehydes.

Y. Okada, H. Taguchi, T. Yokoi, 1997 .

Design and synthesis of opioid mimetics containing pyrazinone ring and examination of their opioid receptor binding activity

Y. Okada, S. Bryant, L. Lazarus, 2002 .

Amino Acids and Peptides. Part 41. Facile Synthesis of 5-Methyl-2(1H)- pyrazinone Derivatives from Dipeptidyl Chloromethyl Ketones.

Y. Okada, H. Taguchi, T. Yokoi, 1995 .

Design of noncovalent trypsin inhibitor based on the X-ray crystal structure of the complex.

K. Tomoo, T. Ishida, Y. Tsuda, 1995, Biochemical and biophysical research communications.

Development of active center-directed plasmin and plasma kallikrein inhibitors and studies on the structure-inhibitory activity relationship.

Y. Okada, S. Okamoto, H. Taguchi, 1993, Chemical & pharmaceutical bulletin.

Prospects for immunotherapeutic proteolytic antibodies.

Y. Nishiyama, S. Paul, S. Planque, 2002, Journal of immunological methods.

Toward Effective HIV Vaccination

J. Symerský, Lei Jin, G. Nitti, 2009, The Journal of Biological Chemistry.

Muscle-Directed Anti-Aβ Single-Chain Antibody Delivery via AAV1 Reduces Cerebral Aβ Load in an Alzheimer’s Disease Mouse Model

S. Ponnazhagan, Robert Lalonde, A. Pattanayak, 2012, Journal of Molecular Neuroscience.

Cross-clade HIV-1 neutralization by an antibody fragment from a lupus phage display library

F. Arnett, Y. Nishiyama, P. Thiagarajan, 2004, AIDS.

Anti-Amyloid-β Single-Chain Antibody Brain Delivery Via AAV Reduces Amyloid Load But May Increase Cerebral Hemorrhages in an Alzheimer's Disease Mouse Model.

J. Cirrito, S. Ponnazhagan, Hong-Duck Kim, 2011, Journal of Alzheimer's disease : JAD.

Covalent reactivity of phosphonate monophenyl esters with serine proteinases: an overlooked feature of presumed transition state analogs.

Y. Nishiyama, G. Burr, S. Paul, 2002, Archives of biochemistry and biophysics.

Obtaining Highly Active Catalytic Antibodies Capable of Enzymatically Cleaving Antigens

H. Taguchi, T. Uda, E. Hifumi, 2022, International journal of molecular sciences.

Finding and characterizing a catalytic antibody light chain, H34, capable of degrading the PD-1 molecule

H. Taguchi, Takunori Harada, T. Uda, 2020, RSC chemical biology.

Carrier-dependent specificity of antibodies to a conserved peptide determinant of gp120.

Y. Nishiyama, C. Hanson, S. Planque, 2003, Vaccine.

Broadly Distributed Chemical Reactivity of Natural Antibodies Expressed in Coordination with Specific Antigen Binding Activity*

Y. Nishiyama, G. Burr, S. Paul, 2003, Journal of Biological Chemistry.

Synthesis of a Covalently Reactive Antigen Analog Derived from a Conserved Sequence of HIV-1 gp120

Y. Nishiyama, G. Burr, S. Paul, 2001 .

Covalent Inactivation of Factor VIII Antibodies from Hemophilia A Patients by an Electrophilic FVIII Analog*

E. Donnachie, K. Pratt, M. Escobar, 2008, Journal of Biological Chemistry.

Identification of the minimal region of peptide derived from ADP‐ribosylation factor1 (ARF1) that inhibits IgE‐mediated mast cell activation

Ryota Uchida, K. Nishida, Y. Fujita, 2019, Molecular immunology.

Metal-dependent amyloid β-degrading catalytic antibody construct.

Y. Nishiyama, S. Paul, S. Planque, 2014, Journal of biotechnology.

Development of an activity-based probe for amyloid β-hydrolyzing antibodies.

Y. Fujita, Y. Tsuda, H. Taguchi, 2016, Bioorganic & medicinal chemistry letters.

THE NATURAL FUNERAL (SHIZENSOU) IN JAPAN TODAY: THE MOVEMENT, BACKGROUND, AND THE NEXT WORLD

H. Taguchi, 2005 .

Structural Diversity Problems and the Solving Method for Antibody Light Chains

R. Kato, H. Taguchi, T. Uda, 2018 .

Direct conversion of a general antibody to its catalytic antibody and corresponding applications —Importance and role of Pro95 in CDR-3—

H. Taguchi, T. Uda, E. Hifumi, 2023, Proceedings of the Japan Academy. Series B, Physical and biological sciences.

Role of the constant region domain in the structural diversity of human antibody light chains

R. Kato, H. Taguchi, T. Uda, 2017, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Naturally Occurring Proteolytic Antibodies SELECTIVE IMMUNOGLOBULIN M-CATALYZED HYDROLYSIS OF HIV gp120*

A. Edmundson, Y. Nishiyama, C. Hanson, 2004 .

Autoantibody-catalyzed hydrolysis of amyloid beta peptide.

J. Symerský, R. Friedland, A. Edmundson, 2008, The Journal of biological chemistry.

6-(4-Amino-2-butyl-imidazoquinolyl)-norleucine: Toll-like receptor 7 and 8 agonist amino acid for self-adjuvanting peptide vaccine

K. Nishida, Y. Fujita, H. Taguchi, 2016, Amino Acids.

Metal-dependent amyloid β-degrading catalytic antibody construct.

Y. Nishiyama, S. Paul, S. Planque, 2014, Journal of biotechnology.

Role of the constant region domain in the structural diversity of human antibody light chains

R. Kato, H. Taguchi, T. Uda, 2017, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.