C. Freise

发表

Wideband MRE and static mechanical indentation of human liver specimen: sensitivity of viscoelastic constants to the alteration of tissue structure in hepatic fibrosis.

Abbas Samani, Martin Stockmann, Patrick Asbach, 2014, Journal of biomechanics.

An active extract of Lindera obtusiloba inhibits adipogenesis via sustained Wnt signaling and exerts anti-inflammatory effects in the 3T3-L1 preadipocytes.

R. Somasundaram, M. Zeitz, Kiyoung Kim, 2010, The Journal of nutritional biochemistry.

Inhibition of vascular calcification by block of intermediate conductance calcium-activated potassium channels with TRAM-34.

U. Querfeld, C. Freise, 2014, Pharmacological research.

Protective effects of the polyphenols (+)-episesamin and sesamin against PDGF-BB-induced activation of vascular smooth muscle cells are mediated by induction of haem oxygenase-1 and inhibition of mitogenic signalling

U. Querfeld, C. Freise, K. Sommer, 2015 .

Chronic kidney disease induces a systemic microangiopathy, tissue hypoxia and dysfunctional angiogenesis

B. Reglin, A. Pries, U. Querfeld, 2018, Scientific Reports.

Reduced Microvascular Density in Omental Biopsies of Children with Chronic Kidney Disease

N. Grabe, B. Lahrmann, G. Ariceta, 2016, PloS one.

(+)-Episesamin inhibits adipogenesis and exerts anti-inflammatory effects in 3T3-L1 (pre)adipocytes by sustained Wnt signaling, down-regulation of PPARγ and induction of iNOS.

R. Somasundaram, M. Zeitz, D. Seehofer, 2013, The Journal of nutritional biochemistry.

A hepatoprotective Lindera obtusiloba extract suppresses growth and attenuates insulin like growth factor-1 receptor signaling and NF-kappaB activity in human liver cancer cell lines

R. Somasundaram, M. Zeitz, D. Seehofer, 2011, BMC complementary and alternative medicine.

The inhibitor of Ca2+-dependent K+ channels TRAM-34 blocks growth of hepatocellular carcinoma cells via downregulation of estrogen receptor alpha mRNA and nuclear factor-kappaB

R. Somasundaram, D. Seehofer, J. Hoyer, 2013, Investigational New Drugs.

Collagen XIV and a related recombinant fragment protect human vascular smooth muscle cells from calcium‐/phosphate‐induced osteochondrocytic transdifferentiation

U. Querfeld, C. Freise, Veronika Bobb, 2017, Experimental cell research.

Expression of intercellular adhesion molecule-1 in the cortex of preserved rat kidneys.

M. Bedolli, C. Freise, S. Jung, 2001, The Journal of surgical research.

Uraemic extracellular vesicles augment osteogenic transdifferentiation of vascular smooth muscle cells via enhanced AKT signalling and PiT‐1 expression

B. Hamm, M. Taupitz, U. Querfeld, 2021, Journal of cellular and molecular medicine.

K+‐channel inhibition reduces portal perfusion pressure in fibrotic rats and fibrosis associated characteristics of hepatic stellate cells

R. Somasundaram, D. Seehofer, R. Köhler, 2015, Liver international : official journal of the International Association for the Study of the Liver.

Hydroxyproline-containing collagen analogs trigger the release and activation of collagen-sequestered proMMP-2 by competition with prodomain-derived peptide P33-42

D. Schuppan, M. Muche, R. Somasundaram, 2011, Fibrogenesis & tissue repair.

Visualization of Inflammation in Experimental Colitis by Magnetic Resonance Imaging Using Very Small Superparamagnetic Iron Oxide Particles

Oliver J. Klein, M. Taupitz, I. Sack, 2022, Frontiers in Physiology.

The matrix metalloproteinases 2 and 9 initiate uraemic vascular calcifications.

P. Stawowy, U. Querfeld, B. Hocher, 2016, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

A Lindera obtusiloba Extract Blocks Calcium-/Phosphate-Induced Transdifferentiation and Calcification of Vascular Smooth Muscle Cells and Interferes with Matrix Metalloproteinase-2 and Metalloproteinase-9 and NF-κB

U. Querfeld, K. Y. Kim, C. Freise, 2015, Evidence-based complementary and alternative medicine : eCAM.

Wnt signaling contributes to vascular calcification by induction of matrix metalloproteinases

U. Querfeld, C. Freise, Nadja Kretzschmar, 2016, BMC Cardiovascular Disorders.

Absolute Configuration of Antifi brotic (+)-Episesamin Isolated from Lindera obtusiloba BLUME

R. Somasundaram, F. Emmerling, M. Rühl, 2011, Zeitschrift fur Naturforschung. C, Journal of biosciences.

The lignan (+)‐episesamin interferes with TNF‐α‐induced activation of VSMC via diminished activation of NF‐ĸB, ERK1/2 and AKT and decreased activity of gelatinases

U. Querfeld, C. Freise, 2015, Acta physiologica.

Alpha-single chains of collagen type VI inhibit the fibrogenic effects of triple helical collagen VI in hepatic stellate cells

D. Chan, E. Sahin, D. Schuppan, 2021, PloS one.

The alpha 2 chain of collagen type VI sequesters latent proforms of matrix-metalloproteinases and modulates their activation and activity.

M. Muche, R. Somasundaram, M. Zeitz, 2009, Matrix biology : journal of the International Society for Matrix Biology.

The synthetic hydroxyproline-containing collagen analogue (Gly-Pro-Hyp)10 promotes enzymatic activity of matrixmetalloproteinase-2 in vitro.

R. Somasundaram, M. Heimesaat, R. Farndale, 2012, European journal of microbiology & immunology.

The synthetic hydroxyproline-containing collagen analogue (Gly-Pro-Hyp)10 ameliorates acute DSS colitis.

U. Göbel, R. Somasundaram, M. Zeitz, 2012, European journal of microbiology & immunology.

(+)-Episesamin exerts anti-neoplastic effects in human hepatocellular carcinoma cell lines via suppression of nuclear factor-kappa B and inhibition of MMP-9

R. Somasundaram, M. Zeitz, D. Seehofer, 2012, Investigational New Drugs.

The Elongated First Fibronectin Type III Domain of Collagen XIV Is an Inducer of Quiescence and Differentiation in Fibroblasts and Preadipocytes*

Hadi Al-Hasani, D. Schuppan, R. Somasundaram, 2005, Journal of Biological Chemistry.

Extracts of Lindera obtusiloba induce antifibrotic effects in hepatic stellate cells via suppression of a TGF-beta-mediated profibrotic gene expression pattern.

R. Somasundaram, M. Zeitz, Kiyoung Kim, 2009, The Journal of nutritional biochemistry.

Arterial tissue transcriptional profiles associate with tissue remodeling and cardiovascular phenotype in children with end-stage kidney disease

F. Schaefer, U. Querfeld, U. Bauer, 2019, Scientific Reports.

Chronic kidney disease induces a systemic microangiopathy, tissue hypoxia and dysfunctional angiogenesis

B. Reglin, A. Pries, U. Querfeld, 2018, Scientific Reports.

Non-contact monitoring of agitation and use of a sheltering device in patients with dementia in emergency departments: a feasibility study

R. Somasundaram, W. Friesdorf, W. Hopfenmüller, 2020, BMC Psychiatry.