A. Prakash

发表

Development of a Synthetic 3-ketosteroid Δ1-dehydrogenase for the Generation of a Novel Catabolic Pathway Enabling Cholesterol Degradation in Human Cells

L. Pannell, R. Honkanen, B. D'Arcy, 2019, Scientific Reports.

Destabilization of the PCNA trimer mediated by its interaction with the NEIL1 DNA glycosylase

S. Doublié, S. Wallace, A. Prakash, 2016, Nucleic acids research.

The NEIL1 G83D germline DNA glycosylase variant induces genomic instability and cellular transformation

C. Marsden, S. Doublié, J. Sweasy, 2017, Oncotarget.

Extracellular vesicles - mediating and delivering cardioprotection in acute myocardial infarction and heart failure.

S. Hernandez-Resendiz, D. Hausenloy, S. Ong, 2020, Conditioning medicine.

Computational framework for generating synthetic signal peptides

Ryan G. Benton, T. Johnsten, A. Prakash, 2022, BCB.

A Method for Computationally Constructing Eukaryotic Synthetic Signal Peptide Sequences

Ryan G. Benton, T. Johnsten, A. Prakash, 2021, bioRxiv.

Stabilization of a G-Quadruplex from Unfolding by Replication Protein A Using Potassium and the Porphyrin TMPyP4

G. Borgstahl, Fabien Kieken, L. Marky, 2011, Journal of nucleic acids.

The Fpg/Nei family of DNA glycosylases: substrates, structures, and search for damage.

S. Doublié, S. Wallace, A. Prakash, 2012, Progress in molecular biology and translational science.

A. Prakash, M. Saki, Aishwarya Prakash, 2017, Free radical biology & medicine.

The structure and function of replication protein A in DNA replication.

G. Borgstahl, A. Prakash, Aishwarya Prakash, 2012, Sub-cellular biochemistry.

Identification of the DNA-Binding Domains of Human Replication Protein A That Recognize G-Quadruplex DNA

G. Borgstahl, M. Ouellette, L. Marky, 2011, Journal of nucleic acids.

Characterization of long G4-rich enhancer-associated genomic regions engaging in a novel loop:loop ‘G4 Kissing’ interaction

Jingshan Huang, Glen M Borchert, Dominika Houserova, 2020, Nucleic acids research.

Exploiting DNA Endonucleases to Advance Mechanisms of DNA Repair

R. Sobol, A. Prakash, Marlo K. Thompson, 2021, Biology.

Replication Protein A (RPA) Hampers the Processive Action of APOBEC3G Cytosine Deaminase on Single-Stranded DNA

G. Borgstahl, I. Rogozin, I. Waisertreiger, 2011, PloS one.

Biochemical and structural characterization of two variants of uncertain significance in the PMS2 gene

A. Prakash, B. D’Arcy, J. Blount, 2019, Human mutation.

Mitochondrial DNA: Epigenetics and environment

Nidhi Sharma, A. Prakash, Monica S Pasala, 2019, Environmental and molecular mutagenesis.

Base Excision Repair in the Mitochondria

S. Doublié, A. Prakash, Aishwarya Prakash, 2015, Journal of cellular biochemistry.

The C-terminal tail of the NEIL1 DNA glycosylase interacts with the human mitochondrial single-stranded DNA binding protein.

Nidhi Sharma, S. Chakravarthy, W. Copeland, 2018, DNA repair.

The changing landscape of Lynch syndrome due to PMS2 mutations

A. Prakash, J. Blount, Aishwarya Prakash, 2018, Clinical genetics.

Human Replication Protein A−Rad52−Single-Stranded DNA Complex: Stoichiometry and Evidence for Strand Transfer Regulation by Phosphorylation†

Carol Kolar, Gloria E. O. Borgstahl, Xiaoyi Deng, 2009, Biochemistry.

Stability and sub-cellular localization of DNA polymerase β is regulated by interactions with NQO1 and XRCC1 in response to oxidative stress

Nidhi Sharma, A. Wilk, J. Slyšková, 2019, Nucleic acids research.

Stability and sub-cellular localization of DNA polymerase β is regulated by interactions with NQO1 and XRCC1 in response to oxidative stress

Robert, Nidhi Sharma, A. Wilk, 2019, Nucleic acids research.

Novel interaction interfaces mediate the interaction between the NEIL1 DNA glycosylase and mitochondrial transcription factor A

P. Prevelige, S. Chakravarthy, A. Prakash, 2022, Frontiers in Cell and Developmental Biology.

Phosphorylation Sites Identified in the NEIL1 DNA Glycosylase Are Potential Targets for the JNK1 Kinase

S. Doublié, A. Prakash, V. Cao, 2016, PloS one.

PMS2 variant results in loss of ATPase activity without compromising mismatch repair

C. Deivanayagam, A. Prakash, Zhengrong Yang, 2022, Molecular genetics & genomic medicine.

The Antitumor Drug LB-100 Is a Catalytic Inhibitor of Protein Phosphatase 2A (PPP2CA) and 5 (PPP5C) Coordinating with the Active-Site Catalytic Metals in PPP5C

R. Honkanen, M. Swingle, A. Prakash, 2019, Molecular Cancer Therapeutics.

Genome and cancer single nucleotide polymorphisms of the human NEIL1 DNA glycosylase: activity, structure, and the effect of editing.

S. Doublié, J. Sweasy, B. Carroll, 2014, DNA repair.

Editorial: Regulatory networks in genome stability pathways

A. Prakash, Nicholas W. Ashton, T. Moiseeva, 2023, Frontiers in Genetics.

Polβ/XRCC1 heterodimerization dictates DNA damage recognition and basal Polβ protein levels without interfering with mouse viability or fertility.

C. Koczor, R. Sobol, A. Prakash, 2023, DNA repair.

Targeting phosphatases in cancer: suppression of many versus the ablation of one

R. Honkanen, A. Prakash, B. D’Arcy, 2019, Oncotarget.

Supplemental Information for : Human Replication Protein A , Rad 52 , ssDNA Complex : Stoichiometry and Evidence for Strand Transfer Regulation by Phosphorylation †

G. Borgstahl, G. Oakley, K. Dhar, 2009 .