C. Larson

发表

CX3CL1-Fc treatment prevents atherosclerosis in Ldlr KO mice

A. Fanjul, K. Ley, J. Olefsky, 2018, Molecular metabolism.

'Reverse' alpha-ketoamide-based p38 MAP kinase inhibitors.

H. Nakanishi, R. Dahl, E. Saiah, 2008, Bioorganic & medicinal chemistry letters.

CCAAT Enhancer-Binding Protein ( C / EBP ) and AML 1 ( CBF a 2 ) Synergistically Activate the Macrophage Colony-Stimulating Factor Receptor Promoter

D. Tenen, Dong-er Zhang, S. Hiebert, 1995 .

Chronic fractalkine administration improves glucose tolerance and pancreatic endocrine function

Jong Bae Seo, A. Fanjul, J. Olefsky, 2018, The Journal of clinical investigation.

Peptide Binding Identifies an ERα Conformation That Generates Selective Activity in Multiple In Vitro Assays

A. Negro-Vilar, C. Larson, H. Seidel, 2005, Journal of biomolecular screening.

Limited proteolysis and site-directed mutagenesis of the NF-κB p50 DNA-binding subunit

William Arbuthnot Sir Lane, G. Verdine, M. Sodeoka, 1993 .

MetAP2 inhibition increases energy expenditure through direct action on brown adipocytes

A. Fanjul, P. Farrell, J. Bilakovics, 2019, The Journal of Biological Chemistry.

Functional Characterization of a Purified, Recombinant NF-κB/IκB Complex

R. Müller, F. Mercurio, C. Larson, 1999 .

Purification of the major histocompatibility complex class I transcription factor H2TF1. The full-length product of the nfkb2 gene.

P. Sharp, G. Nabel, R. Schmid, 1993, The Journal of biological chemistry.

Using Target Engagement Biomarkers to Predict Clinical Efficacy of MetAP2 Inhibitors

A. Fanjul, C. Zopf, Christopher Mcbride, 2019, The Journal of Pharmacology and Experimental Therapeutics.

Human T-cell leukemia virus type I (HTLV-I) and blood transfusion.

H. Taswell, C. Larson, 1988, Mayo Clinic proceedings.

Apoptotic Responses in Squamous Carcinoma and Epithelial Cells to Small-Molecule Toll-like Receptor Agonists Evaluated with Automated Cytometry

H. Lebrec, Richard L. Miller, C. Larson, 2006, Journal of biomolecular screening.

Antiinflammatory glucocorticoid receptor ligand with reduced side effects exhibits an altered protein–protein interaction profile

E. Vajda, J. Rosen, J. Miner, 2007, Proceedings of the National Academy of Sciences.

The design and synthesis of novel alpha-ketoamide-based p38 MAP kinase inhibitors.

H. Nakanishi, R. Dahl, E. Saiah, 2008, Bioorganic & medicinal chemistry letters.

Discovery and characterization of an inhibitor of glucosylceramide synthase.

K. Ogilvie, J. Nuss, S. Richards, 2012, Journal of medicinal chemistry.

Expression of human prostatic acid phosphatase gene is regulated by upstream negative and positive elements.

R. Taylor, C. Larson, M. Lin, 2000, Biochimica et biophysica acta.

A high-capacity column for affinity purification of sequence-specific DNA-binding proteins

Gregory L. Verdine, Christopher J. Larson, G. Verdine, 1992, Nucleic Acids Res..

Truncated BRCA2 is cytoplasmic: implications for cancer-linked mutations.

F. Gage, I. Verma, F. Gage, 1999, Proceedings of the National Academy of Sciences of the United States of America.

A DNA-bending protein interacts with an essential upstream regulatory element of the human embryonic beta-like globin gene

M. Dyer, G. Verdine, M. Baron, 1996, Molecular and cellular biology.

Time-dependent inhibition of PHD2

Lihong Shi, C. Grimshaw, J. Ermolieff, 2017, Bioscience reports.

Translational Pharmacology and Physiology of Brown Adipose Tissue in Human Disease and Treatment.

C. Larson, 2019, Handbook of experimental pharmacology.

cGMP and Brown Adipose Tissue.

A. Pfeifer, L. Hoffmann, C. Larson, 2016, Handbook of experimental pharmacology.

KR-003048, a potent, orally active inhibitor of p38 mitogen-activated protein kinase.

H. Nakanishi, R. Dahl, E. Saiah, 2010, European journal of pharmacology.

Structure of the human NF‐κB p52 homodimer‐DNA complex at 2.1 Å resolution

Gregory L. Verdine, Patrick Cramer, Christoph W. Müller, 1997 .

TLR7 agonist 852A inhibition of tumor cell proliferation is dependent on plasmacytoid dendritic cells and type I IFN.

C. Dumitru, M. Tomai, J. Vasilakos, 2008, Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research.

Increased HDL Cholesterol and ApoA-I in Humans and Mice Treated With a Novel SR-BI Inhibitor

A. Tall, M. Ishibashi, D. Masson, 2009, Arteriosclerosis, thrombosis, and vascular biology.

Optimization of alpha-ketoamide based p38 inhibitors through modifications to the region that binds to the allosteric site.

J. Urban, C. Lum, H. Nakanishi, 2010, Bioorganic & medicinal chemistry letters.

The persistent need for insulin sensitizers and other disease-modifying anti-diabetic drugs

C. Larson, 2014, Expert review of endocrinology & metabolism.

A multifunctional plasmid for protein expression by ECPCR: overproduction of the p50 subunit of NF-κB

G. Verdine, M. Sodeoka, K. Leclair, 1993 .

Glucocorticoid Drugs, Evolution of

J. Rosen, J. Miner, C. Larson, 2003 .

Structure of the human NF-kappaB p52 homodimer-DNA complex at 2.1 A resolution.

G L Verdine, P. Cramer, C. Müller, 1997, The EMBO journal.

Disruption of NOTCH signaling by a small molecule inhibitor of the transcription factor RBPJ

J. Cashman, F. Oswald, M. Mercola, 2019, Scientific Reports.

Discovery of potent, reversible MetAP2 inhibitors via fragment based drug discovery and structure based drug design-Part 2.

J. Lawson, Christopher Mcbride, P. Farrell, 2016, Bioorganic & medicinal chemistry letters.

CCAAT enhancer-binding protein (C/EBP) and AML1 (CBF alpha2) synergistically activate the macrophage colony-stimulating factor receptor promoter

D. Tenen, Dong-er Zhang, S. Hiebert, 1996, Molecular and cellular biology.

Disruption of NOTCH signaling by a small molecule inhibitor of the transcription factor RBPJ

J. Cashman, F. Oswald, M. Mercola, 2019, Scientific Reports.