L. Quartara

发表

Ala scan analogues of HOE 140. Synthesis and biological activities.

A Rizzi, D Regoli, C. Maggi, 2000, European journal of medicinal chemistry.

A structure-activity study on the bradykinin B1 antagonist desArg10-HOE 140: The alanine scan

C. Maggi, P. Rovero, A. Triolo, 2006, Letters in Peptide Science.

The N-terminal of icatibant and bradykinin interact with the same Asp residues in the human B2 receptor.

C. Maggi, L. Rotondaro, S. Zappitelli, 2004, European journal of pharmacology.

MEN 11270, A novel selective constrained peptide antagonist with high affinity at the human B2 kinin receptor.

C. Maggi, G. Calo’, M. Criscuoli, 1999, The Journal of pharmacology and experimental therapeutics.

Nonpeptide antagonists for kinin receptors

C. Maggi, M. Altamura, L. Quartara, 1999, Regulatory Peptides.

Bicyclic homodetic peptide libraries: comparison of synthetic strategies for their solid-phase synthesis.

E. Giralt, F. Albericio, C. Maggi, 2003, Journal of combinatorial chemistry.

A different molecular interaction of bradykinin and the synthetic agonist FR190997 with the human B2 receptor: evidence from mutational analysis

C. Maggi, L. Rotondaro, W. Reichert, 2003, British journal of pharmacology.

Design and structure of a novel Neurokinin A receptor antagonist cyclo(-Met1-Asp2-Trp3-Phe4-Dap5-Leu6-)cyclo(2β-5β)

C. Maggi, A. Lombardi, M. Saviano, 1995 .

Conformational rigidity versus flexibility in a novel peptidic neurokinin A receptor antagonist

C. Maggi, A. Lombardi, C. Pedone, 1995, Journal of peptide science : an official publication of the European Peptide Society.

MEN16132, a kinin B2 receptor antagonist, prevents the endogenous bradykinin effects in guinea-pig airways.

C. Maggi, L. Quartara, S. Giuliani, 2008, European journal of pharmacology.

MEN16132, a Novel Potent and Selective Nonpeptide Kinin B2 Receptor Antagonist: In Vivo Activity on Bradykinin-Induced Bronchoconstriction and Nasal Mucosa Microvascular Leakage in Anesthetized Guinea Pigs

C. Maggi, A. Lecci, L. Quartara, 2005, Journal of Pharmacology and Experimental Therapeutics.

Comparison of the molecular interactions of two antagonists, MEN16132 or icatibant, at the human kinin B2 receptor

C. Maggi, L. Rotondaro, S. Zappitelli, 2011, British journal of pharmacology.

ligands and mechanisms of cellular activation

C. Maggi, L. Quartara, 1997 .

The tachykinin NK1 receptor. Part I: Ligands and mechanisms of cellular activation

C. Maggi, L. Quartara, 1997, Neuropeptides.

Cardiovascular effects of peptide kinin B2 receptor antagonists in rats.

C. Maggi, A. Lecci, L. Quartara, 2002, Canadian journal of physiology and pharmacology.

Role of C-terminal amidation on the biological activity of neurokinin A derivatives with agonist and antagonist properties.

C. Maggi, C. Goso, P. Rovero, 1993, The Journal of pharmacology and experimental therapeutics.

Tachykinin receptors antagonists: from research to clinic.

M. Altamura, L. Quartara, 2006, Current drug targets.

Pharmacological profile of the novel mammalian tachykinin, hemokinin 1

C. Maggi, A. Lecci, L. Quartara, 2002, British journal of pharmacology.

In vivo evidence for tachykininergic transmission using a new NK-2 receptor-selective antagonist, MEN 10,376.

C. Maggi, P. Rovero, A. Lecci, 1991, The Journal of pharmacology and experimental therapeutics.

Tachykinin receptors in the guinea-pig isolated bronchi.

C. Maggi, P. Rovero, P. Santicioli, 1991, European journal of pharmacology.

Solid‐phase synthesis of MEN 11270, a new cyclic peptide kinin B2 receptor antagonist 1 2

C. Maggi, S. Mauro, A. Triolo, 2000, Journal of peptide science : an official publication of the European Peptide Society.

In vitro and in vivo activity of analogues of the kinin B2 receptor antagonist MEN11270

C. Maggi, A. Lecci, L. Quartara, 2002 .

MEN 11420 (Nepadutant), a novel glycosylated bicyclic peptide tachykinin NK2 receptor antagonist

C. Maggi, A. Lecci, F. Arcamone, 1998, British journal of pharmacology.

Differences between peptide and nonpeptide B(2) bradykinin receptor antagonists in blocking bronchoconstriction and hypotension induced by bradykinin in anesthetized Guinea pigs.

C. Maggi, A. Lecci, L. Quartara, 2001, The Journal of pharmacology and experimental therapeutics.

Heterogeneity of tachykinin NK-2 receptors in rabbit, guinea-pig and human smooth muscles

C. Maggi, P. Rovero, A. Renzetti, 1992, Neuropeptides.

NK2 tachykinin receptors and contraction of circular muscle of the human colon: characterization of the NK2 receptor subtype.

C. Maggi, P. Rovero, L. Quartara, 1991, European journal of pharmacology.

Design and synthesis of novel sulfonamide-containing bradykinin hB(2) receptor antagonists. Synthesis and structure-relationships of α,α-tetrahydropyranylglycine.

C. Maggi, A. Ettorre, C. I. Fincham, 2012, Bioorganic & medicinal chemistry.

MEN16132, a novel potent and selective nonpeptide antagonist for the human bradykinin B2 receptor. In vitro pharmacology and molecular characterization.

C. Maggi, L. Rotondaro, A. Lecci, 2005, European journal of pharmacology.

A new class of pseudopeptide antagonists of the kinin B1 receptor containing alkyl spacers.

C. Toniolo, F. Formaggio, C. Maggi, 1999, Journal of medicinal chemistry.

Bradykinin B2 and GPR100 receptors: a paradigm for receptor signal transduction pharmacology

C. Maggi, L. Rotondaro, S. Zappitelli, 2004, British journal of pharmacology.

Characterization of [3H]MEN 11420, a novel glycosylated peptide antagonist radioligand of the tachykinin NK2 receptor.

C. Maggi, M. Criscuoli, A. Lippi, 1998, Biochemical and biophysical research communications.

Interaction of linear and cyclic peptide antagonists at the human B2 kinin receptor

C. Maggi, L. Rotondaro, S. Zappitelli, 2002, Peptides.

Comparison of tachykinin NK1 and NK2 receptors in the circular muscle of the guinea‐pig ileum and proximal colon

A. Sisto, C. Maggi, L. Quartara, 1994, British journal of pharmacology.

MEN 10,573 and MEN 10,612, novel cyclic pseudopeptides which are potent tachykinin NK-2 receptor antagonists

C. Maggi, L. Quartara, R. Patacchini, 1993, Regulatory Peptides.

Further evidence for the existence of NK2 tachykinin receptor subtypes

C. Maggi, P. Rovero, M. Astolfi, 1991, British journal of pharmacology.

Bicyclic peptides as type I/type II β‐turn scaffolds

A. Lombardi, M. Saviano, C. Pedone, 1998 .

Differential effects of BQ‐123 against endothelin‐1 and endothelin‐3 on the rat vas deferens: evidence for an atypical endothelin receptor

C. Maggi, L. Quartara, R. Patacchini, 1993, British journal of pharmacology.

Peptide and non-peptide bradykinin B2 receptor agonists and antagonists: a reappraisal of their pharmacology in the guinea-pig ileum.

C. Maggi, A. Lecci, L. Quartara, 2000, European journal of pharmacology.

Bradykinin analogs containing the 4‐amino‐2‐benzazepin‐3‐one scaffold at the C‐terminus

D. Tourwé, S. Ballet, L. Quartara, 2007, Journal of peptide science : an official publication of the European Peptide Society.

3-Phenyl-5-carbomethoxymethylene-5H-isoxazolo[4,5-e][1,4]diazepine-6,8(4H,7H)-dione: a new seven membered binuclear system

L. Quartara, D. Giomi, R. Nesi, 1987 .

Synthesis of cyclic peptides on solid support

P. Rovero, L. Quartara, G. Fabbri, 1991 .

Pharmacological evaluation of α and β human tachykinin NK2 receptor splice variants expressed in CHO cells

C. Maggi, L. Rotondaro, A. Faiella, 2004 .

Peptide‐based tachykinin NK2 receptor antagonists

C. Maggi, P. Rovero, L. Quartara, 1995, Medicinal research reviews.

The tachykinin NK1 receptor. Part II: Distribution and pathophysiological roles

C. Maggi, L. Quartara, 1998, Neuropeptides.

Peptide-Based Tachykinin NK2 Receptor Antagonists

C. Maggi, P. Rovero, L. Quartara, 1995 .

Heterogeneity of NK-2 tachykinin receptors in hamster and rabbit smooth muscles

C. Maggi, L. Quartara, R. Patacchini, 1992, Regulatory Peptides.

A review of the design, synthesis and biological activity of the bicyclic hexapeptide tachykinin NK2 antagonist MEN 10627

C. Maggi, A. Lombardi, C. Pedone, 1996, Regulatory Peptides.

N-terminal truncated analogs of men 10376 as tachykinin NK-2 receptor antagonists.

C. Maggi, P. Rovero, A. Renzetti, 1992, Life sciences.

Tachykinin receptors in the guinea‐pig renal pelvis: activation by exogenous and endogenous tachykinins

C. Maggi, L. Quartara, R. Patacchini, 1992, British journal of pharmacology.

Structure-activity study of the C-terminal residue of MEN 10207 tachykinin antagonist

C. Maggi, P. Rovero, M. Astolfi, 1992, Peptides.

Solid-phase synthesis of neurokinin A antagonists. Comparison of the Boc and Fmoc methods.

P. Rovero, L. Quartara, G. Fabbri, 2009, International journal of peptide and protein research.

Effect of scyliorhinin I and synthetic scyliorhinin I derivatives at mammalian tachykinin NK1, NK2 and NK3 receptors.

C. Maggi, K. Rolka, G. Kupryszewski, 1993, European journal of pharmacology.

MEN 10,627, a novel polycyclic peptide antagonist of tachykinin NK2 receptors.

C. Maggi, C. Goso, C. Pedone, 1994, The Journal of pharmacology and experimental therapeutics.

A New potent and highly selective, long lasting, peptide based Neurokinin A antagonist: Rational design of MEN 10627

C. Maggi, A. Lombardi, C. Pedone, 1994 .

Effect of several bicyclic peptide and cyclic pseudopeptide tachykinin NK2 receptor antagonists in the human isolated ileum and colon

C. Maggi, M. Lazzeri, L. Quartara, 1997, Neuropeptides.

Effect of several bicyclic peptide and cyclic pseudopeptide tachykinin NK2 receptor antagonists in the human isolated urinary bladder.

C. Maggi, M. Lazzeri, L. Quartara, 1996, Journal of autonomic pharmacology.

Influence of lipophilicity on the biological activity of cyclic pseudopeptide NK-2 receptor antagonists.

C. Maggi, V. Pavone, F. Arcamone, 1994, Journal of medicinal chemistry.

Preliminary mutational analysis of the human kinin B2 receptor for nonpeptide antagonist ligands recognition.

C. Maggi, L. Rotondaro, S. Zappitelli, 2002, Canadian journal of physiology and pharmacology.

Preliminary mutational analysis of the human kinin B 2 receptor for nonpeptide antagonist ligands

C. Maggi, L. Rotondaro, S. Zappitelli, 2002 .

Tachykinin receptor antagonists in clinical trials

C. Maggi, M. Altamura, L. Quartara, 2009, Expert opinion on investigational drugs.

A structure-activity study on the bradykinin B1 antagonist desArg10-HOE 140: The alanine scan

Carlo A. Maggi, Paolo Rovero, C. Maggi, 1999, Letters in Peptide Science.

New features of isoxazole chemistry. The reaction of ethyl 4-nitro-3-phenylisoxazole-5-carboxylate with 2,3-dimethylbuta-1,3-diene

L. Quartara, D. Giomi, R. Nesi, 1986 .

Pharmacological evaluation of alpha and beta human tachykinin NK(2) receptor splice variants expressed in CHO cells.

C. Maggi, L. Rotondaro, A. Faiella, 2004, European journal of pharmacology.

Characterization of the tachykinin neurokinin-2 receptor in the human urinary bladder by means of selective receptor antagonists and peptidase inhibitors.

C. Maggi, P. Rovero, L. Quartara, 1993, The Journal of pharmacology and experimental therapeutics.

Synthesis of the bradykinin B1 antagonist [desArg10]HOE 140 on 2-chlorotrityl resin

P. Rovero, L. Quartara, S. Viganò, 1996, Letters in Peptide Science.

Synthesis and biological activity of new bradykinin pseudopeptide B1 receptor agonists containing alkylic spacers

C. Maggi, P. Rovero, M. Tancredi, 1997 .

Agonist activity at the kinin B1 receptor: structural requirements of the central tetrapeptide.

C. Toniolo, F. Formaggio, C. Maggi, 2001, Journal of Medicinal Chemistry.

Design and Synthesis of Novel Sulfonamide-Containing Bradykinin hB2 Receptor Antagonists. 2. Synthesis and Structure−Activity Relationships of α,α-Cycloalkylglycine Sulfonamides

R. Terracciano, C. Maggi, D. Fattori, 2007 .

Design and Synthesis of Novel Sulfonamide-Containing Bradykinin hB2 Receptor Antagonists. 1. Synthesis and SAR of α,α-Dimethylglycine Sulfonamides

R. Terracciano, C. Maggi, D. Fattori, 2006 .

Site-directed mutagenesis at the human B2 receptor and molecular modelling to define the pharmacophore of non-peptide bradykinin receptor antagonists.

C. Maggi, L. Rotondaro, A. Faiella, 2004, Biochemical pharmacology.

Design and synthesis of novel sulfonamide-containing bradykinin hB2 receptor antagonists. 2. Synthesis and structure-activity relationships of alpha,alpha-cycloalkylglycine sulfonamides.

R. Terracciano, C. Maggi, D. Fattori, 2007, Journal of medicinal chemistry.

Design and synthesis of novel sulfonamide-containing bradykinin hB2 receptor antagonists. 1. Synthesis and SAR of alpha,alpha-dimethylglycine sulfonamides.

R. Terracciano, C. Maggi, D. Fattori, 2006, Journal of medicinal chemistry.

Activity of cyclic pseudopeptide antagonists at peripheral tachykinin receptors.

C. Maggi, C. Goso, M. Astolfi, 1995, The Journal of pharmacology and experimental therapeutics.

A Novel Rigid -Turn Molecular Scaffold

Vincenzo Pavone, Ornella Maglio, Flavia Nastri, 1998 .