S. Meini

发表

Ala scan analogues of HOE 140. Synthesis and biological activities.

A Rizzi, D Regoli, C. Maggi, 2000, European journal of medicinal chemistry.

A structure-activity study on the bradykinin B1 antagonist desArg10-HOE 140: The alanine scan

C. Maggi, P. Rovero, A. Triolo, 2006, Letters in Peptide Science.

The N-terminal of icatibant and bradykinin interact with the same Asp residues in the human B2 receptor.

C. Maggi, L. Rotondaro, S. Zappitelli, 2004, European journal of pharmacology.

MEN 11270, A novel selective constrained peptide antagonist with high affinity at the human B2 kinin receptor.

C. Maggi, G. Calo’, M. Criscuoli, 1999, The Journal of pharmacology and experimental therapeutics.

Structure–Activity Study of the Peptides P5U and Urantide by the Development of Analogues Containing Uncoded Amino Acids at Position 9

E. Novellino, P. Grieco, I. Gomez-Monterrey, 2016, ChemMedChem.

Nonpeptide antagonists for kinin receptors

C. Maggi, M. Altamura, L. Quartara, 1999, Regulatory Peptides.

Mutagenesis at the human tachykinin NK(2) receptor to define the binding site of a novel class of antagonists.

C. Maggi, L. Rotondaro, M. Altamura, 2004, European journal of pharmacology.

Arachidonic acid‐induced bronchomotor responses are partially mediated by release of sensory neuropeptides from capsaicin‐sensitive structures

S. Manzini, P. Geppetti, S. Meini, 1989, British journal of pharmacology.

Knee osteoarthritis: a role for bradykinin?

C. Maggi, S. Meini, 2008, Inflammation Research.

A different molecular interaction of bradykinin and the synthetic agonist FR190997 with the human B2 receptor: evidence from mutational analysis

C. Maggi, L. Rotondaro, W. Reichert, 2003, British journal of pharmacology.

Antagonism of Bradykinin B2 Receptor Prevents Inflammatory Responses in Human Endothelial Cells by Quenching the NF-kB Pathway Activation

C. Maggi, S. Donnini, M. Ziche, 2014, PloS one.

Pharmacologic and neurochemical evidence for the activation of capsaicin-sensitive sensory nerves by lipoxin A4 in guinea pig bronchus.

P. Blumberg, A. Szallasi, S. Manzini, 1992, The American review of respiratory disease.

CHAPTER 180 – Tachykinins and Their Receptors in the Lung

A. Lecci, S. Meini, 2006 .

Involvement of capsaicin‐sensitive nerves in the bronchomotor effects of arachidonic acid and melittin: a possible role for lipoxin A4

S. Manzini, S. Meini, 1991, British journal of pharmacology.

MEN16132, a Novel Potent and Selective Nonpeptide Kinin B2 Receptor Antagonist: In Vivo Activity on Bradykinin-Induced Bronchoconstriction and Nasal Mucosa Microvascular Leakage in Anesthetized Guinea Pigs

C. Maggi, A. Lecci, L. Quartara, 2005, Journal of Pharmacology and Experimental Therapeutics.

Comparison of the molecular interactions of two antagonists, MEN16132 or icatibant, at the human kinin B2 receptor

C. Maggi, L. Rotondaro, S. Zappitelli, 2011, British journal of pharmacology.

Antagonist profile of ibodutant at the tachykinin NK2 receptor in guinea pig isolated bronchi.

C. Maggi, A. Lecci, P. Santicioli, 2013, European Journal of Pharmacology.

Cardiovascular effects of peptide kinin B2 receptor antagonists in rats.

C. Maggi, A. Lecci, L. Quartara, 2002, Canadian journal of physiology and pharmacology.

Characterization of the tachykinin NK2 receptor in the human bronchus: influence of amastatin‐sensitive metabolic pathways

C. Maggi, S. Manzini, M. Astolfi, 1994, British journal of pharmacology.

Tachykinin control of ferret airways: Mucus secretion, bronchoconstriction and receptor mapping

J. Mak, D. Rogers, S. Meini, 1993, Neuropeptides.

Involvement of capsaicin-sensitive structures in arachidonic acid-induces motor effects in guinea pig isolated bronchus

S. Manzini, S. Meini, 1990 .

Pharmacological profile of the novel mammalian tachykinin, hemokinin 1

C. Maggi, A. Lecci, L. Quartara, 2002, British journal of pharmacology.

Pharmacological evaluation of the role of cyclooxygenase isoenzymes on the micturition reflex following experimental cystitis in rats

L. Birder, C. Maggi, A. Lecci, 2000, British journal of pharmacology.

Inflammation modifies the role of cyclooxygenases in the contractile responses of the rat detrusor smooth muscle to kinin agonists.

C. Maggi, A. Lecci, M. Criscuoli, 1998, The Journal of pharmacology and experimental therapeutics.

In vitro and in vivo activity of analogues of the kinin B2 receptor antagonist MEN11270

C. Maggi, A. Lecci, L. Quartara, 2002 .

Kinin Receptor Antagonists

C. Maggi, S. Meini, 2001 .

Differences between peptide and nonpeptide B(2) bradykinin receptor antagonists in blocking bronchoconstriction and hypotension induced by bradykinin in anesthetized Guinea pigs.

C. Maggi, A. Lecci, L. Quartara, 2001, The Journal of pharmacology and experimental therapeutics.

Effect of procaine on learning and hypoxia-induced amnesia

C. Ghelardini, M. Malcangio, A. Bartolini, 1988 .

Design and synthesis of novel sulfonamide-containing bradykinin hB(2) receptor antagonists. Synthesis and structure-relationships of α,α-tetrahydropyranylglycine.

C. Maggi, A. Ettorre, C. I. Fincham, 2012, Bioorganic & medicinal chemistry.

MEN16132, a novel potent and selective nonpeptide antagonist for the human bradykinin B2 receptor. In vitro pharmacology and molecular characterization.

C. Maggi, L. Rotondaro, A. Lecci, 2005, European journal of pharmacology.

Radioligand binding characterization of the bradykinin B(2) receptor in the rabbit and pig ileal smooth muscle.

C. Maggi, P. Santicioli, S. Meini, 2010, European journal of pharmacology.

Novel effects mediated by bradykinin and pharmacological characterization of bradykinin B2 receptor antagonism in human synovial fibroblasts

C. Maggi, S. Meini, F. Bellucci, 2009, British journal of pharmacology.

Characterization of kinin receptors in human cultured detrusor smooth muscle cells

P. Santicioli, M. Lazzeri, S. Meini, 2007, British journal of pharmacology.

Characterization of bradykinin B2 receptor antagonists in human and rat urinary bladder

C. Maggi, A. Lecci, M. Lazzeri, 2000 .

A new class of pseudopeptide antagonists of the kinin B1 receptor containing alkyl spacers.

C. Toniolo, F. Formaggio, C. Maggi, 1999, Journal of medicinal chemistry.

The longitudinal muscle of rat ileum as a sensitive monoreceptor assay for bradykinin B1 receptors

C. Maggi, A. Lecci, S. Meini, 1996, British journal of pharmacology.

Pharmacological analysis of the local and reflex responses to bradykinin on rat urinary bladder motility in vivo

C. Maggi, A. Lecci, S. Meini, 1995, British journal of pharmacology.

Bradykinin B2 and GPR100 receptors: a paradigm for receptor signal transduction pharmacology

C. Maggi, L. Rotondaro, S. Zappitelli, 2004, British journal of pharmacology.

The effect of thiorphan and epithelium removal on contractions and tachykinin release produced by activation of capsaicin-sensitive afferents in the guinea-pig isolated bronchus

C. Maggi, P. Santicioli, A. Meli, 2004, Naunyn-Schmiedeberg's Archives of Pharmacology.

Bradykinin and B2 receptor antagonism in rat and human articular chondrocytes

C. Maggi, S. Meini, F. Bellucci, 2011, British journal of pharmacology.

Pharmacology of an original and selective nonpeptide antagonist ligand for the human tachykinin NK2 receptor.

C. Maggi, L. Rotondaro, S. Zappitelli, 2005, European journal of pharmacology.

MEN15596, a novel nonpeptide tachykinin NK2 receptor antagonist.

C. Maggi, A. Lecci, R. Catalioto, 2006, European journal of pharmacology.

Modulation by stereoselective inhibition of cyclo‐oxygenase of electromechanical coupling in the guinea‐pig isolated renal pelvis

C. Maggi, P. Santicioli, G. Carganico, 1995, British journal of pharmacology.

Characterization of ibodutant at NK(2) receptor in human colon.

P. Bechi, C. Maggi, P. Santicioli, 2013, European journal of pharmacology.

Modulation on C‐ and N‐Terminal Moieties of a Series of Potent and Selective Linear Tachykinin NK2 Receptor Antagonists

C. Maggi, R. Nannicini, A. Triolo, 2010, ChemMedChem.

Pharmacological characterization of the bradykinin B2 receptor antagonist MEN16132 in rat in vitro bioassays.

C. Maggi, P. Santicioli, S. Meini, 2009, European journal of pharmacology.

Interaction of linear and cyclic peptide antagonists at the human B2 kinin receptor

C. Maggi, L. Rotondaro, S. Zappitelli, 2002, Peptides.

New conformationally homogeneous β‐turn antagonists of the human B2 kinin receptor

R. Terracciano, C. I. Fincham, E. Monteagudo, 2001, Journal of peptide science : an official publication of the European Peptide Society.

Effect of dexamethasone on cyclophosphamide-induced cystitis in rats: lack of relation with bradykinin B1 receptor-mediated motor responses.

C. Maggi, A. Lecci, M. Criscuoli, 1999, European journal of pharmacology.

GR 73,632 and [Glu(OBzl)11]substance P are selective agonists for the septide-sensitive tachykinin NK1 receptor in the rat urinary bladder

C. Maggi, P. Rovero, A. Lecci, 1995, Neuropeptides.

In vivo effects of neurokinin B on rat urinary bladder motility: Involvement of tachykinin NK1 and NK2 receptors

C. Maggi, A. Lecci, S. Meini, 1994, Neuropeptides.

Comparison of tachykinin NK1 and NK2 receptors in the circular muscle of the guinea‐pig ileum and proximal colon

A. Sisto, C. Maggi, L. Quartara, 1994, British journal of pharmacology.

Tachykinin NK1 receptor subtypes in the rat urinary bladder

C. Maggi, S. Meini, R. Patacchini, 1994, British journal of pharmacology.

Effects of capsaicin, tachykinins, calcitonin gene-related peptide and bradykinin in the pig iris sphincter muscle

C. Maggi, P. Geppetti, S. Meini, 1990, Naunyn-Schmiedeberg's Archives of Pharmacology.

Comparative antagonist pharmacology at the native mouse bradykinin B2 receptor: radioligand binding and smooth muscle contractility studies

C. Maggi, P. Santicioli, S. Meini, 2007, British journal of pharmacology.

Fasitibant prevents the bradykinin and interleukin 1β synergism on prostaglandin E2 release and cyclooxygenase 2 expression in human fibroblast-like synoviocytes

C. Maggi, A. Fioravanti, M. Galeazzi, 2012, Naunyn-Schmiedeberg's Archives of Pharmacology.

Peptide and non-peptide bradykinin B2 receptor agonists and antagonists: a reappraisal of their pharmacology in the guinea-pig ileum.

C. Maggi, A. Lecci, L. Quartara, 2000, European journal of pharmacology.

Kinin B1 receptor-mediated motor responses in normal or inflamed rat urinary bladder in vivo

C. Maggi, A. Lecci, M. Criscuoli, 1999, Regulatory Peptides.

Tachykinin receptors and intestinal motility

V. Zagorodnyuk, C. Maggi, A. Lecci, 1997 .

Contractile effect of endothelin on isolated iris sphincter muscle of the pig.

S. Manzini, P. Geppetti, S. Meini, 1989, European journal of pharmacology.

Bradykinin analogs containing the 4‐amino‐2‐benzazepin‐3‐one scaffold at the C‐terminus

D. Tourwé, S. Ballet, L. Quartara, 2007, Journal of peptide science : an official publication of the European Peptide Society.

Bradykinin antagonists modified with dipeptide mimetic β-turn inducers

M. Scrima, A. D'Ursi, M. Chelli, 2006 .

A way to manage the thermal flexibility of ligand candidates for bioassays

S. Menichetti, C. Nativi, M. Altamura, 2006 .

Pharmacological evaluation of α and β human tachykinin NK2 receptor splice variants expressed in CHO cells

C. Maggi, L. Rotondaro, A. Faiella, 2004 .

Nociceptin and the micturition reflex

C. Maggi, A. Lecci, S. Meini, 2000, Peptides.

Tachykinin-mediated effect of nociceptin in the rat urinary bladder in vivo.

C. Maggi, A. Lecci, P. Santicioli, 2000, European journal of pharmacology.

Nitric oxide is the mediator of tachykinin NK3 receptor-induced relaxation in the circular muscle of the guinea-pig ileum.

C. Maggi, S. Meini, R. Patacchini, 1993, European journal of pharmacology.

MEN 10,627, a novel polycyclic peptide antagonist of tachykinin NK2 receptors.

C. Maggi, C. Goso, C. Pedone, 1994, The Journal of pharmacology and experimental therapeutics.

In vivo evidence for the involvement of tachykinin NK3 receptors in the hexamethonium-resistant inhibitory transmission in the rat colon

C. Maggi, A. Lecci, R. Giorgio, 1996, Naunyn-Schmiedeberg's Archives of Pharmacology.

Tachykinin NK1 receptorsubtypes intheraturinary bladder

C. Maggi, S. Meini, R. Patacchini, 1994 .

Antihistaminic antinociception: Research about mechanism of action

C. Ghelardini, M. Malcangio, A. Bartolini, 1988 .

Procaine antidepressant effect

C. Ghelardini, M. Malcangio, A. Bartolini, 1988 .

Studies on the analgesic mechanism of some antiarrhythmic drugs

C. Ghelardini, M. Malcangio, A. Bartolini, 1988 .

Procaine dramatically increases evoked tritium efflux from guinea-pig ileum preloaded with [3H]-choline

A. Gori, C. Ghelardini, M. Malcangio, 1988 .

The stimulating action of very low doses of antagonist drugs, or the otherwise generally higher sensitivity of presynaptic autoreceptors

C. Ghelardini, M. Malcangio, A. Bartolini, 1988 .

Preliminary mutational analysis of the human kinin B2 receptor for nonpeptide antagonist ligands recognition.

C. Maggi, L. Rotondaro, S. Zappitelli, 2002, Canadian journal of physiology and pharmacology.

Preliminary mutational analysis of the human kinin B 2 receptor for nonpeptide antagonist ligands

C. Maggi, L. Rotondaro, S. Zappitelli, 2002 .

Effect of longitudinal muscle-myenteric plexus removal and indomethacin on the response to tachykinin NK-2 and NK-3 receptor agonists in the circular muscle of the guinea-pig ileum.

C. Maggi, S. Meini, R. Patacchini, 1994, Journal of autonomic pharmacology.

Evidence for a capsaicin‐sensitive, tachykinin‐mediated, component in the NANC contraction of the rat urinary bladder to nerve stimulation

C. Maggi, S. Meini, 1994, British journal of pharmacology.

Synovial fluid levels of bradykinin correlate with biochemical markers for cartilage degradation and inflammation in knee osteoarthritis.

C. Maggi, A. Fioravanti, G. Guidelli, 2013, Osteoarthritis and cartilage.

Booster immunization with a fractional dose of Prevnar 13 affects cell-mediated immune response but not humoral immunity in CD-1 mice

L. Digilio, R. Catalioto, M. Altamura, 2021, Heliyon.

Propagation of impulses in the guinea-pig ureter and its blockade by calcitonin gene-related peptide (CGRP)

C. Maggi, P. Santicioli, S. Meini, 2004, Naunyn-Schmiedeberg's Archives of Pharmacology.

Calcitonin gene related peptide as inhibitory neurotransmitter in the ureter.

C. Maggi, P. Santicioli, S. Meini, 1995, Canadian journal of physiology and pharmacology.

Differences in electromechanical coupling between bradykinin and the nonpeptide kinin B2 receptor agonist, FR 190997, in the circular muscle of guinea-pig colon

C. Maggi, P. Santicioli, R. Catalioto, 2001, Naunyn-Schmiedeberg's Archives of Pharmacology.

Isbufylline, a xanthine derivative, inhibits bronchoconstrictor responses produced by stimulation of capsaicin-sensitive sensory nerves in guinea-pig: 'In vitro' and 'in vivo' evidence.

S. Manzini, S. Meini, S. Evangelista, 1993, Pulmonary pharmacology.

Pharmacodynamic profile of isbufylline, a new antibronchospastic xanthine devoid of central excitatory actions.

S. Manzini, L. Beani, T. Antonelli, 1990, Arzneimittel-Forschung.

Discovery of a new series of potent and selective linear tachykinin NK2 receptor antagonists.

C. Maggi, A. Lecci, R. Nannicini, 2007, Journal of Medicinal Chemistry.

Multifaceted Approach to Determine the Antagonist Molecular Mechanism and Interaction of Ibodutant ([1-(2-Phenyl-1R-{[1-(tetrahydropyran-4-ylmethyl)-piperidin-4-ylmethyl]-carbamoyl}-ethylcarbamoyl)-cyclopentyl]-amide) at the Human Tachykinin NK2 Receptor

P. Santicioli, S. Meini, A. Giolitti, 2009, Journal of Pharmacology and Experimental Therapeutics.

α,α‐Cyclopentaneglycine Dipeptides Capped with Biaryls as Tachykinin NK2 Receptor Antagonists

A. Sisto, D. Fattori, A. Ettorre, 2008, ChemMedChem.

Tachykinin Receptor Assays

S. Meini, Carlo Alberto Maggi, 1998, Current protocols in pharmacology.

Structural characterization of lipopeptide agonists for the bradykinin B2 receptor.

C. Maggi, E. Nardi, A. Papini, 2001, Biopolymers.

A structure-activity study on the bradykinin B1 antagonist desArg10-HOE 140: The alanine scan

Carlo A. Maggi, Paolo Rovero, C. Maggi, 1999, Letters in Peptide Science.

Pharmacological evaluation of alpha and beta human tachykinin NK(2) receptor splice variants expressed in CHO cells.

C. Maggi, L. Rotondaro, A. Faiella, 2004, European journal of pharmacology.

Lead optimization of P5U and urantide: discovery of novel potent ligands at the urotensin-II receptor.

E. Novellino, P. Grieco, I. Gomez-Monterrey, 2014, Journal of medicinal chemistry.

New insight into the binding mode of peptides at urotensin‐II receptor by Trp‐constrained analogues of P5U and urantide

E. Novellino, P. Grieco, I. Gomez-Monterrey, 2013, Journal of peptide science : an official publication of the European Peptide Society.

New insight into the binding mode of peptide ligands at Urotensin-II receptor: structure-activity relationships study on P5U and urantide.

E. Novellino, P. Grieco, I. Gomez-Monterrey, 2009, Journal of medicinal chemistry.

Antagonist profile of ibodutant at the tachykinin NK(2) receptor in guinea pig isolated bronchi.

C. Maggi, A. Lecci, P. Santicioli, 2013, European Journal of Pharmacology.

Synthesis and biological activity of new bradykinin pseudopeptide B1 receptor agonists containing alkylic spacers

C. Maggi, P. Rovero, M. Tancredi, 1997 .

Evidence for the presence of a septide-sensitive tachykinin receptor in the circular muscle of the guinea-pig ileum.

C. Maggi, S. Meini, R. Patacchini, 1993, European journal of pharmacology.

Fasitibant prevents the bradykinin and interleukin 1β synergism on prostaglandin E2 release and cyclooxygenase 2 expression in human fibroblast-like synoviocytes

C. Maggi, A. Fioravanti, M. Galeazzi, 2012, Naunyn-Schmiedeberg's Archives of Pharmacology.

Blockade of nociceptive sensory afferent activity of the rat knee joint by the bradykinin B2 receptor antagonist fasitibant.

C. Belmonte, C. Maggi, A. Gomis, 2013, Osteoarthritis and cartilage.

Agonist activity at the kinin B1 receptor: structural requirements of the central tetrapeptide.

C. Toniolo, F. Formaggio, C. Maggi, 2001, Journal of Medicinal Chemistry.

Design and Synthesis of Novel Sulfonamide-Containing Bradykinin hB2 Receptor Antagonists. 2. Synthesis and Structure−Activity Relationships of α,α-Cycloalkylglycine Sulfonamides

R. Terracciano, C. Maggi, D. Fattori, 2007 .

Design and Synthesis of Novel Sulfonamide-Containing Bradykinin hB2 Receptor Antagonists. 1. Synthesis and SAR of α,α-Dimethylglycine Sulfonamides

R. Terracciano, C. Maggi, D. Fattori, 2006 .

Site-directed mutagenesis at the human B2 receptor and molecular modelling to define the pharmacophore of non-peptide bradykinin receptor antagonists.

C. Maggi, L. Rotondaro, A. Faiella, 2004, Biochemical pharmacology.

Design and synthesis of novel sulfonamide-containing bradykinin hB2 receptor antagonists. 2. Synthesis and structure-activity relationships of alpha,alpha-cycloalkylglycine sulfonamides.

R. Terracciano, C. Maggi, D. Fattori, 2007, Journal of medicinal chemistry.

Design and synthesis of novel sulfonamide-containing bradykinin hB2 receptor antagonists. 1. Synthesis and SAR of alpha,alpha-dimethylglycine sulfonamides.

R. Terracciano, C. Maggi, D. Fattori, 2006, Journal of medicinal chemistry.

P. Santicioli, R. Bugianesi, V. D'Aranno, 2016, British journal of pharmacology.

Characterization of bradykinin B(2) receptor antagonists in human and rat urinary bladder.

C. Maggi, A. Lecci, M. Lazzeri, 2000, European journal of pharmacology.

Characterization of ibodutant at NK(2) receptor in human colon.

P. Santicioli, S. Meini, C. Catalani, 2013, European journal of pharmacology.

P. Santicioli, S. Meini, A. Giolitti, 2009, Journal of Pharmacology and Experimental Therapeutics.