O. Howard

发表

β-Defensins: Linking Innate and Adaptive Immunity Through Dendritic and T Cell CCR6

Ji Ming Wang, J. Wang, O. Chertov, 1999 .

Complementary DNA and derived amino acid sequence of the beta subunit of human complement protein C8: identification of a close structural and ancestral relationship to the alpha subunit and C9.

A. Rao, O. Howard, J. Sodetz, 1987, Biochemistry.

Bidirectional Heterologous Desensitization of Opioid and Chemokine Receptors

T. Rogers, J. Oppenheim, O. Howard, 2000, Annals of the New York Academy of Sciences.

Melanoma cell-derived exosomes alter macrophage and dendritic cell functions in vitro.

J. Minárovits, E. Duda, K. Nagy, 2012, Immunology letters.

The Scaffold Protein Cybr Is Required for Cytokine-Modulated Trafficking of Leukocytes In Vivo

Antonio Rosato, Lino Tessarollo, A. Rosato, 2006, Molecular and Cellular Biology.

Monocyte Chemotactic Protein-2 Activates CCR5 and Blocks CD4/CCR5-mediated HIV-1 Entry/Replication*

W. Gong, Ji Ming Wang, P. Gray, 1998, The Journal of Biological Chemistry.

CD27 signals through PKC in human B cell lymphomas.

O. Howard, B. Erlichman, 1999, Cytokine.

Characterization of chenodeoxycholic acid as an endogenous antagonist of the G-coupled formyl peptide receptors

J. Wang, J. Oppenheim, D. Yang, 2000, Inflammation Research.

Dendritic Cell Maturation and Activation and Pancreatic Ribonuclease, Induce Members, Eosinophil-Derived Neurotoxin Human Ribonuclease A Superfamily

S. Kingsmore, D. Newton, D. Patel, 2004 .

Monocyte Chemotactic Protein-2 (MCP-2) Uses CCR1 AND CCR2B as Its Functional Receptors*

W. Gong, Ji Ming Wang, D. Kuhns, 1997, The Journal of Biological Chemistry.

Small molecule inhibitor of HIV‐1 cell fusion blocks chemokine receptor‐mediated function

N. Tarasova, C. Michejda, T. Korte, 1998, Journal of leukocyte biology.

Inhibition of in vitro and in vivo HIV replication by a distamycin analogue that interferes with chemokine receptor function: a candidate for chemotherapeutic and microbicidal application.

M. Hollingshead, D. Clanton, William Q. Rice, 1998, Journal of medicinal chemistry.

Pervanadate simulates the effects of interleukin-2 (IL-2) in human T cells and provides evidence for the activation of two distinct tyrosine kinase pathways by IL-2.

W. Farrar, R. Erwin, O. Howard, 1994, The Journal of biological chemistry.

Interferon affects nuclear proteins in cells of clinically sensitive chronic myelogenous leukemia patients.

H. Kantarjian, A. Cork, M. Talpaz, 1990, Blood.

A phosphatase activity present in peripheral blood myeloid cells of chronic myelogenous leukemia patients but not normal individuals alters nuclear protein binding to transcriptional enhancers of interferon-inducible genes.

H. Kantarjian, A. Deisseroth, M. Talpaz, 1990, The Journal of clinical investigation.

Up-regulated expression and activation of the orphan chemokine receptor, CCRL2, in rheumatoid arthritis.

A. Matsukawa, T. Yoshimura, H. Mizuta, 2004, Arthritis and rheumatism.

The differential ability of IL-8 and neutrophil-activating peptide-2 to induce attenuation of chemotaxis is mediated by their divergent capabilities to phosphorylate CXCR2 (IL-8 receptor B).

K. Matsushima, N. Mukaida, A. Ben-Baruch, 1997, Journal of immunology.

to migrate CXCR3 and CXCR5 expressing lymphocytes and immature dendritic cells Autoantigens signal through chemokine receptors: uveitis antigens induce

S. Su, P. Plotz, R. Caspi, 2013 .

Variants of CCR5, which are permissive for HIV-1 infection, show distinct functional responses to CCL3, CCL4 and CCL5

M. Carrington, J. Turpin, M. Dean, 2005, Genes and Immunity.

Inhibition of RANTES/CCR1-mediated chemotaxis by cosalane and related compounds.

M. Cushman, J. Oppenheim, O. Howard, 2001, Bioorganic & Medicinal Chemistry Letters.

Expression Maturation : Correlation with Receptor fMLP and C 5 a Upon Dendritic Cell Differential Regulation of Responsiveness to Howard and

S. Stoll, Xin Chen, J. Oppenheim, 2000 .

Opiates Transdeactivate Chemokine Receptors: δ and μ Opiate Receptor–mediated Heterologous Desensitization

D. Taub, R. Snyderman, J. Resau, 1998, The Journal of experimental medicine.

Interleukin-2 induces tyrosine phosphorylation of the vav proto-oncogene product in human T cells: lack of requirement for the tyrosine kinase lck.

W. Farrar, R. Erwin, O. Howard, 1993, The Biochemical journal.

Analysis of Interleukin-2-dependent Signal Transduction through the Shc/Grb2 Adapter Pathway

J. Johnston, M. Goldsmith, W. Greene, 1995, The Journal of Biological Chemistry.

Monocyte Chemoattractant Protein-1/CCL2 Produced by Stromal Cells Promotes Lung Metastasis of 4T1 Murine Breast Cancer Cells

Y. Liu, Keqiang Chen, Ji Ming Wang, 2013, PloS one.

Activation of JAK3, but not JAK1, is critical for IL-2-induced proliferation and STAT5 recruitment by a COOH-terminal region of the IL-2 receptor beta-chain.

W. Farrar, J. O’Shea, R. Kirken, 1995, Cytokine.

Vascular endothelial growth factor and basic fibroblast growth factor induce expression of CXCR4 on human endothelial cells: In vivo neovascularization induced by stromal-derived factor-1alpha.

H. Kleinman, H. Young, M. Anver, 1999, The American journal of pathology.

The diverse role of chemokines in tumor progression: prospects for intervention (Review).

W. Murphy, R. Salcedo, L. Welniak, 2001, International journal of molecular medicine.

New Directions in the Biology and Therapy of Chronic Myeloid Leukemia

Wei Zhang, M. Andreeff, H. Kantarjian, 1992 .

LEC induces chemotaxis and adhesion by interacting with CCR1 and CCR8.

J. Oppenheim, O. Howard, O. Howard, 2000, Blood.

Complementary DNA and derived amino acid sequence of the alpha subunit of human complement protein C8: evidence for the existence of a separate alpha subunit messenger RNA.

H. Colten, S. Ng, A. Rao, 1987, Biochemistry.

Vascular endothelial growth factor and basic fibroblast growth factor induce expression of CXCR4 on human endothelial cells: In vivo neovascularization induced by stromal-derived factor-1alpha.

H. Kleinman, H. Young, M. Anver, 1999, The American journal of pathology.

Shikonin, a component of antiinflammatory Chinese herbal medicine, selectively blocks chemokine binding to CC chemokine receptor-1.

J. Oppenheim, O. Howard, X. Chen, 2001, International immunopharmacology.

Naturally Occurring CCR5 Extracellular and Transmembrane Domain Variants Affect HIV-1 Co-receptor and Ligand Binding Function*

A. Maynard, J. Oppenheim, J. Turpin, 1999, The Journal of Biological Chemistry.

Inhibition of the expression and function of chemokine receptors on human CD4+ leukocytes by HIV-1 envelope protein gp120.

F. Ruscetti, S. Su, J. Wang, 1999, Chemical immunology.

HIV-1 envelope gp120 inhibits the monocyte response to chemokines through CD4 signal-dependent chemokine receptor down-regulation.

C. Broder, L. Arthur, J. Resau, 1998, Journal of immunology.

HIV-1 envelope gp41 is a potent inhibitor of chemoattractant receptor expression and function in monocytes.

F. Ruscetti, S. Su, J. Wang, 1998, The Journal of clinical investigation.

Signal-Dependent Chemokine Receptor Response to Chemokines Through CD 4 HIV-1 Envelope gp 120 Inhibits the Monocyte

C. Broder, L. Arthur, J. Resau, 1998 .

Differential Regulation of Responsiveness to fMLP and C5a Upon Dendritic Cell Maturation: Correlation with Receptor Expression1 2

S. Stoll, Xin Chen, J. Oppenheim, 2000, The Journal of Immunology.

Cutting edge: immature dendritic cells generated from monocytes in the presence of TGF-beta 1 express functional C-C chemokine receptor 6.

J. Oppenheim, De Yang, D. Yang, 1999, Journal of immunology.

Human Ribonuclease A Superfamily Members, Eosinophil-Derived Neurotoxin and Pancreatic Ribonuclease, Induce Dendritic Cell Maturation and Activation1

S. Kingsmore, D. Newton, S. Rybak, 2004, The Journal of Immunology.

Mg2+- or Mn2+-dependent p-nitrophenylphosphatase activity is present in Ehrlich ascites tumor cells.

I. Javeri, O. Howard, J. Maxwell, 1984, Archives of biochemistry and biophysics.

The chemokine kidnapping receptor of HHV8.

W. Farrar, O. Howard, 1998, The Journal of clinical investigation.

Painful Pathways Induced by TLR Stimulation of Dorsal Root Ganglion Neurons

J. Cohen, K. Buzas, Kening Wang, 2011, The Journal of Immunology.

Prolactin recruits STAT1, STAT3 and STAT5 independent of conserved receptor tyrosines TYR402, TYR479, TYR515 and TYR580

H. Rui, W. Farrar, R. Kirken, 1996, Molecular and Cellular Endocrinology.

Growth signaling and JAK2 association mediated by membrane-proximal cytoplasmic regions of prolactin receptors.

W. Farrar, R. Kirken, O. Howard, 1994, The Journal of biological chemistry.

Hck expression correlates with granulocyte-macrophage colony-stimulating factor-induced proliferation in HL-60 cells.

D. Longo, W. Farrar, D. Linnekin, 1994, Blood.

Transactivation of the epidermal growth factor receptor by formylpeptide receptor exacerbates the malignant behavior of human glioblastoma cells.

X. Bian, Jian Huang, W. Gong, 2007, Cancer research.

The G-protein-coupled formylpeptide receptor FPR confers a more invasive phenotype on human glioblastoma cells

X. Bian, W. Gong, J. Wang, 2010, British Journal of Cancer.

Formylpeptide receptor FPR and the rapid growth of malignant human gliomas.

X. Bian, W. Farrar, W. Gong, 2005, Journal of the National Cancer Institute.

Effects of astragali radix on the growth of different cancer cell lines.

J. Oppenheim, O. Howard, O. Howard, 2003, World journal of gastroenterology.

Reduced risk of AIDS lymphoma in individuals heterozygous for the CCR5-delta32 mutation.

J. Goedert, M. Carrington, J. Margolick, 1999, Cancer research.

Structural domains of interleukin-2 receptor beta critical for signal transduction: kinase association and nuclear complex-formation.

W. Farrar, R. Kirken, O. Howard, 1995, The Biochemical journal.

Regulation of the leucocyte chemoattractant receptor FPR in glioblastoma cells by cell differentiation.

X. Bian, Jian Huang, W. Gong, 2009, Carcinogenesis.

Suppression of breast cancer by chemical modulation of vulnerable zinc fingers in estrogen receptor

E. Appella, W. Farrar, Xiaohu Zhang, 2004, Nature Medicine.

Involvement of JAK-family tyrosine kinases in hematopoietin receptor signal transduction.

W. Farrar, R. Kirken, O. Howard, 1994, Progress in growth factor research.

Characterization of a class 3 tyrosine kinase.

W. Farrar, D. Kelvin, L. Lee, 1992, Oncogene.

Advances in Brief Reduced Risk of AIDS Lymphoma in Individuals Heterozygous for the CCR 5D 32 Mutation 1

J. Goedert, M. Carrington, J. Margolick, 1999 .

Chemokines: progress toward identifying molecular targets for therapeutic agents.

A. Ben-Baruch, J. Oppenheim, O. Howard, 1996, Trends in biotechnology.

Signalling by Cytokines

W. Farrar, B. Kawasaki, A. Gamero, 2005 .

The eighth component of human complement: evidence that it is an oligomeric serum protein assembled from products of three different genes.

S. Ng, A. Rao, O. Howard, 1987, Biochemistry.

Soluble tumor necrosis factor receptor: inhibition of human immunodeficiency virus activation.

W. Farrar, C. Smith, R. Goodwin, 1993, Proceedings of the National Academy of Sciences of the United States of America.

The myeloid receptor TREM2 exacerbates DSS-induced colitis and promotes colitis-associated cancer (TUM4P.916)

W. Linehan, B. Rini, J. Finke, 2014, Journal of Immunology.