J. Furman

发表

Early Engineering Approaches to Improve Peptide Developability and Manufacturability

M. Chiu, M. Hunter, J. Furman, 2014, The AAPS Journal.

Calcineurin proteolysis in astrocytes: Implications for impaired synaptic function.

D. Wilcock, H. Abdul, P. Nelson, 2016, Biochimica et biophysica acta.

A versatile platform for single- and multiple-unnatural amino acid mutagenesis in Escherichia coli.

P. Schultz, A. Chatterjee, J. Furman, 2013, Biochemistry.

GFRAL is the receptor for GDF15 and the ligand promotes weight loss in mice and nonhuman primates

T. Cash-Mason, M. Hunter, J. Chavez, 2017, Nature Medicine.

FRET and Flow Cytometry Assays to Measure Proteopathic Seeding Activity in Biological Samples.

M. Diamond, J. Furman, 2017, Methods in molecular biology.

Disparate effects of serum on basal and evoked NFAT activity in primary astrocyte cultures

C. Norris, J. Furman, Irina A. Artiushin, 2010, Neuroscience Letters.

Identifying Senescence as a Mode of Chemo Resistance in Ovarian Cancer

R. Frank, J. Furman, Noelle L. Cutter, 2019, International Journal of Applied Science and Technology.

Cognitive Decline in Alzheimer's Disease Is Associated with Selective Changes in Calcineurin/NFAT Signaling

H. Abdul, M. Murphy, H. Levine, 2009, The Journal of Neuroscience.

Depolarization-Mediated Glutamate Release NMDA Receptor Current and Excitotoxicity: Positive Feedback Loop Between Electrophysiological Mechanisms of Delayed

E. Blalock, P. Landfield, H. Abdul, 2015 .

Proteopathic tau seeding predicts tauopathy in vivo

Nigel J. Cairns, David M. Holtzman, D. Holtzman, 2014, Proceedings of the National Academy of Sciences.

Inhibition of Soluble Tumor Necrosis Factor Ameliorates Synaptic Alterations and Ca2+ Dysregulation in Aged Rats

S. Scheff, C. Norris, D. Szymkowski, 2012, PloS one.

Toward a general approach for RNA-templated hierarchical assembly of split-proteins.

A. Badran, D. Segal, I. Ghosh, 2010, Journal of the American Chemical Society.

Calcineurin/NFAT Signaling in Activated Astrocytes Drives Network Hyperexcitability in Aβ-Bearing Mice

G. Gerhardt, M. Lovell, M. Murphy, 2017, The Journal of Neuroscience.

Turn-on DNA damage sensors for the direct detection of 8-oxoguanine and photoproducts in native DNA.

A. Badran, I. Ghosh, J. Furman, 2011, Journal of the American Chemical Society.

A general approach for receptor and antibody-targeted detection of native proteins utilizing split-luciferase reassembly.

R. Wyatt, Yuxing Li, I. Ghosh, 2010, ACS chemical biology.

Evaluating the global CpG methylation status of native DNA utilizing a bipartite split-luciferase sensor.

A. Badran, I. Ghosh, T. Comi, 2011, Analytical chemistry.

Parkinson's disease and multiple system atrophy have distinct α-synuclein seed characteristics

N. Cairns, M. Diamond, E. Song, 2018, The Journal of Biological Chemistry.

Sensitive Detection of Proteopathic Seeding Activity with FRET Flow Cytometry.

M. Diamond, J. Furman, Brandon B. Holmes, 2015, Journal of visualized experiments : JoVE.

Widespread tau seeding activity at early Braak stages

N. Cairns, P. Nelson, M. Diamond, 2016, Acta Neuropathologica.

Systematic evaluation of split-fluorescent proteins for the direct detection of native and methylated DNA.

A. Badran, D. Segal, I. Ghosh, 2009, Bioorganic & medicinal chemistry letters.

Calcineurin and glial signaling: neuroinflammation and beyond

C. Norris, J. Furman, 2014, Journal of Neuroinflammation.

Interleukin-1β-dependent Signaling between Astrocytes and Neurons Depends Critically on Astrocytic Calcineurin/NFAT Activity*

Christopher M Norris, H. Abdul, C. Norris, 2008, Journal of Biological Chemistry.

Ultrasensitive and selective detection of 3-repeat tau seeding activity in Pick disease brain and cerebrospinal fluid

B. Ghetti, B. Caughey, A. Oblak, 2017, Acta Neuropathologica.

Preparation of acute hippocampal slices from rats and transgenic mice for the study of synaptic alterations during aging and amyloid pathology.

Christopher M Norris, C. Norris, J. Furman, 2011, Journal of visualized experiments : JoVE.

Targeting Astrocytes Ameliorates Neurologic Changes in a Mouse Model of Alzheimer's Disease

M. Murphy, C. Norris, L. V. Van Eldik, 2012, The Journal of Neuroscience.

Expression of SORL1 and a novel SORL1 splice variant in normal and Alzheimers disease brain

F. Schmitt, W. Markesbery, S. Younkin, 2009, Molecular Neurodegeneration.

NFATs and Alzheimer's Disease.

H. Abdul, C. Norris, J. Furman, 2010, Molecular and cellular pharmacology.

A Genetically Encoded aza-Michael Acceptor for Covalent Cross-Linking of Protein–Receptor Complexes

Chan Hyuk Kim, P. Schultz, Yu Cao, 2014, Journal of the American Chemical Society.

A turn-on split-luciferase sensor for the direct detection of poly(ADP-ribose) as a marker for DNA repair and cell death.

I. Ghosh, Cliff I. Stains, J. Furman, 2011, Chemical communications.

Blockade of Astrocytic Calcineurin/NFAT Signaling Helps to Normalize Hippocampal Synaptic Function and Plasticity in a Rat Model of Traumatic Brain Injury

S. Scheff, C. Norris, K. Roberts, 2016, The Journal of Neuroscience.

A long‐acting GDF15 analog causes robust, sustained weight loss and reduction of food intake in an obese nonhuman primate model

Brian J. Geist, A. Nawrocki, Songmao Zheng, 2022, bioRxiv.

Site-specific detection of DNA methylation utilizing mCpG-SEER.

D. Segal, I. Ghosh, Cliff I. Stains, 2006, Journal of the American Chemical Society.

Direct extraction of sunflower seed by filtration-extraction

J. Furman, E. Amadori, O. F. Guzman, 1959 .

TargetingAstrocytesAmelioratesNeurologicChangesina MouseModelofAlzheimer'sDisease

J. Furman, Diana M Sama, M. PaulMurphy, 2012 .

Early Engineering Approaches to Improve Peptide Developability and Manufacturability

M. Chiu, M. Hunter, J. Furman, 2014, The AAPS Journal.

Profiling small molecule inhibitors against helix-receptor interactions: the Bcl-2 family inhibitor BH3I-1 potently inhibits p53/hDM2.

S. Joy, P. Arora, I. Ghosh, 2010, Chemical communications.

Sanders-brown Center on Aging Faculty Publications Aging Calcineurin and Glial Signaling: Neuroinflammation and beyond Repository Citation Calcineurin and Glial Signaling: Neuroinflammation and Beyond

C. Norris, J. Furman, Norris, 2022 .

Targeting Astrocytes Ameliorates Neurologic Changes in a Mouse Targeting Astrocytes Ameliorates Neurologic Changes in a Mouse Model of Alzheimer's Disease Model of Alzheimer's Disease

M. Murphy, C. Norris, A. Bachstetter, 2022 .

Sensitive Detection of Proteopathic Seeding Activity with FRET Flow Cytometry.

M. Diamond, J. Furman, Brandon B. Holmes, 2015, Journal of visualized experiments : JoVE.

Calcineurin and glial signaling: neuroinflammation and beyond

C. Norris, J. Furman, 2014, Journal of Neuroinflammation.