K. Herath

发表

Localization of Fatty Acyl and Double Bond Positions in Phosphatidylcholines Using a Dual Stage CID Fragmentation Coupled with Ion Mobility Mass Spectrometry

T. Hankemeier, L. Mitnaul, D. Johns, 2011, Journal of the American Society for Mass Spectrometry.

Demonstration of diet-induced decoupling of fatty acid and cholesterol synthesis by combining gene expression array and 2H2O quantification.

Guanghui Hu, Kenny K. Wong, D. Johns, 2012, American Journal of Physiology. Endocrinology and Metabolism.

The use of stable-isotopically labeled oleic acid to interrogate lipid assembly in vivo: assessing pharmacological effects in preclinical species

D. Johns, Shirly Pinto, R. DeVita, 2011, Journal of Lipid Research.

Quantifying rates of glucose production in vivo following an intraperitoneal tracer bolus.

M. Erion, D. Kelley, Dan Zhou, 2016, American journal of physiology. Endocrinology and metabolism.

Tracer-based estimates of protein flux in cases of incomplete product renewal: evidence and implications of heterogeneity in collagen turnover.

R. Sadygov, D. Kelley, Sheng-ping Wang, 2015, American journal of physiology. Endocrinology and metabolism.

New methodologies for studying lipid synthesis and turnover: looking backwards to enable moving forwards.

M. Cleary, D. Johns, Vinit Shah, 2014, Biochimica et biophysica acta.

Quantifying apoprotein synthesis in rodents: coupling LC-MS/MS analyses with the administration of labeled water

Michael E. Lassman, Kenny K. Wong, D. Johns, 2012, Journal of Lipid Research.

Isolation, structure, and biological activity of Phaeofungin, a cyclic lipodepsipeptide from a Phaeosphaeria sp. Using the Genome-Wide Candida albicans Fitness Test.

T. Roemer, Jesús Martín, F. Vicente, 2013, Journal of natural products.

Discovery of FabH/FabF Inhibitors from Natural Products

Jun Wang, John F. Barrett, Lynn L. Silver, 2006, Antimicrobial Agents and Chemotherapy.

Isolation, structure elucidation, and antibacterial activity of methiosetin, a tetramic acid from a tropical sooty mold (Capnodium sp.).

J. Phillips, F. Vicente, R. Donald, 2012, Journal of natural products.

Isolation, enzyme-bound structure, and activity of platensimycin A1 from Streptomyces platensis

J. W. Becker, S. Soisson, Sheo B. Singh, 2009 .

Isolation, enzyme-bound structure and antibacterial activity of platencin A1 from Streptomyces platensis.

J. W. Becker, S. Soisson, Sheo B. Singh, 2009, Bioorganic & medicinal chemistry letters.

Structure of homoplatensimide A : a potential key biosynthetic intermediate of platensimycin isolated from Streptomyces platensis

Sheo B. Singh, D. Zink, J. Ondeyka, 2008 .

Isolation and structure of platencin: a FabH and FabF dual inhibitor with potent broad-spectrum antibiotic activity.

F. Vicente, R. Cummings, Ó. Salazar, 2007, Angewandte Chemie.

Chemistry of platensimycin

R. Ball, Sheo B. Singh, N. Tsou, 2007 .

Anthrabenzoxocinones from Streptomyces sp. as liver X receptor ligands and antibacterial agents.

Z. Guan, J. Menke, Neelam Sharma, 2005, Journal of natural products.

siRNA-mediated inhibition of SREBP cleavage-activating protein reduces dyslipidemia in spontaneously dysmetabolic rhesus monkeys.

Shirly Pinto, R. Mogg, D. McLaren, 2017, Metabolism: clinical and experimental.

Ketohexokinase knockout mice, a model for essential fructosuria, exhibit altered fructose metabolism and are protected from diet-induced metabolic defects.

G. Pavlovic, Gaochao Zhou, T. Rosahl, 2018, American journal of physiology. Endocrinology and metabolism.

Glucagon receptor antagonism induces increased cholesterol absorption[S]

M. Erion, Vinit Shah, D. Kelley, 2015, Journal of Lipid Research.

Using [2H]water to quantify the contribution of de novo palmitate synthesis in plasma: enabling back-to-back studies.

M. Erion, D. Kelley, T. Roddy, 2018, American journal of physiology. Endocrinology and metabolism.

In vivo D2O labeling to quantify static and dynamic changes in cholesterol and cholesterol esters by high resolution LC/MS[S]

T. Hankemeier, L. Mitnaul, D. Johns, 2011, Journal of Lipid Research.

Equilibration of (2)H labeling between body water and free amino acids: enabling studies of proteome synthesis.

Michael E. Lassman, D. Johns, T. Roddy, 2011, Analytical biochemistry.

The Fatty Acid Synthase Inhibitor Platensimycin Improves Insulin Resistance without Inducing Liver Steatosis in Mice and Monkeys

Margaret S. Wu, D. Kelley, S. Previs, 2016, PloS one.

Quantifying cholesterol synthesis in vivo using 2H2O: enabling back-to-back studies in the same subject

J. Xu, D. Johns, T. Roddy, 2011, Journal of Lipid Research.

Effects of small interfering RNA-mediated hepatic glucagon receptor inhibition on lipid metabolism in db/db mice[S]

Shirly Pinto, T. Roddy, Kristian K. Jensen, 2013, Journal of Lipid Research.

Determination of low levels of 2H-labeling using high-resolution mass spectrometry: application in studies of lipid flux and beyond.

M. Cleary, D. Johns, Vinit Shah, 2014, Rapid communications in mass spectrometry : RCM.

Discovery of structurally diverse natural product antagonists of chemokine receptor CXCR3

Gregory R. Koch, J. Demartino, Z. Guan, 2005, Molecular Diversity.

Effects of siRNA-mediated hepatic glucagon receptor inhibition on lipid metabolism in db/db mice

Shirly Pinto, T. Roddy, Kristian K. Jensen, 2013 .

Headspace analyses of ²H labeling of acetone: enabling studies of fatty acid oxidation in vivo.

D. Johns, T. Roddy, D. McLaren, 2011, Analytical biochemistry.

Structure and semisynthesis of platensimide A, produced by Streptomyces platensis.

Sheo B. Singh, D. Zink, J. Ondeyka, 2008, Organic letters.

Biosynthetic studies of platensimycin.

A. Attygalle, Sheo B. Singh, K. Herath, 2007, Journal of the American Chemical Society.

Thiazomycins, thiazolyl peptide antibiotics from Amycolatopsis fastidiosa.

Sheo B. Singh, D. Zink, J. Barrett, 2009, Journal of natural products.

Isolation and structure elucidation of thiazomycin- a potent thiazolyl peptide antibiotic from Amycolatopsis fastidiosa.

B. Junker, Ó. Salazar, O. Genilloud, 2008, The Journal of antibiotics.

Antibacterial evaluations of thiazomycin- a potent thiazolyl peptide antibiotic from Amycolatopsis fastidiosa.

M. Motyl, C. Gill, Sheo B. Singh, 2008, Journal of antibiotics (Tokyo. 1968).

Isolation and Structures of Novel Fungal Metabolites as Chemokine Receptor (CCR2) Antagonists

Z. Guan, A. Cabello, G. Bills, 2005, The Journal of Antibiotics.

Headspace analyses of acetone: a rapid method for measuring the 2H-labeling of water.

Vinit Shah, T. Roddy, S. Previs, 2010, Analytical biochemistry.

Synthesis and antifungal evaluation of pentyloxyl-diphenylisoxazoloyl pneumocandins and echinocandins.

M. Motyl, P. Mann, Sheo B. Singh, 2013, Bioorganic & medicinal chemistry letters.

Guttiferone I, a new prenylated benzophenone from Garcinia humilis as a liver X receptor ligand.

Z. Guan, D. Stevenson, J. Menke, 2005, Journal of natural products.

Occurrence, distribution, dereplication and efficient discovery of thiazolyl peptides by sensitive-resistant pair screening

Jesús Martín, F. Vicente, O. Genilloud, 2013, The Journal of Antibiotics.

A Potent Thiazolyl Peptide Antibiotic from Amycolatopsis fastidiosa

M. Motyl, C. Gill, Sheo B. Singh, 2009 .

Antibacterial Evaluations of Thiazomycin

M. Motyl, C. Gill, Sheo B. Singh, 2007, The Journal of Antibiotics.

Isolation and Structure Elucidation of Thiazomycin

B. Junker, Ó. Salazar, O. Genilloud, 2007, The Journal of Antibiotics.

Platensimycin is a selective FabF inhibitor with potent antibiotic properties

Jun Wang, Olga Genilloud, Sang Ho Lee, 2006, Nature.

Highly substituted terphenyls as inhibitors of parasite cGMP-dependent protein kinase activity.

Ziqiang Guan, Javier Collado, B. Nare, 2006, Journal of natural products.

Steroidal and Triterpenoidal Fungal Metabolites as Ligands of Liver X Receptors

Ziqiang Guan, Javier Collado, Z. Guan, 2005, The Journal of Antibiotics.

Isolation, structure, and absolute stereochemistry of platensimycin, a broad spectrum antibiotic discovered using an antisense differential sensitivity strategy.

Olga Genilloud, Jun Wang, Francisca Vicente, 2006, Journal of the American Chemical Society.

Discovery of a Small Molecule That Inhibits Cell Division by Blocking FtsZ, a Novel Therapeutic Target of Antibiotics*

D. Cully, F. Vicente, Andrew M. Galgoci, 2003, Journal of Biological Chemistry.

Biosynthetic studies of Nocathiacin-I

Sheo B. Singh, N. Yu, N. Connors, 2008 .

Isolation, structure and biological activity of phomafungin, a cyclic lipodepsipeptide from a widespread tropical Phoma sp.

Scott K. Smith, T. Roemer, F. Vicente, 2009, Bioorganic & medicinal chemistry.

Biosynthetic studies of platencin

A. Attygalle, Sheo B. Singh, K. Herath, 2008 .

Discovery of platencin, a dual FabF and FabH inhibitor with in vivo antibiotic properties

Jun Wang, Olga Genilloud, Oscar Salazar, 2007, Proceedings of the National Academy of Sciences.

Determination of Selectivity and Efficacy of Fatty Acid Synthesis Inhibitors*

D. Schmatz, D. Cully, R. Painter, 2005, Journal of Biological Chemistry.

Isolation, structure, absolute stereochemistry, and HIV-1 integrase inhibitory activity of integrasone, a novel fungal polyketide.

D. Hazuda, Z. Guan, G. Bills, 2004, Journal of natural products.

Integramides A and B, two novel non-ribosomal linear peptides containing nine C(alpha)-methyl amino acids produced by fungal fermentations that are inhibitors of HIV-1 integrase.

D. Hazuda, Z. Guan, K. Silverman, 2002, Organic letters.

Circumambulatory movement of negative charge ("ring walk") during gas-phase dissociation of 2,3,4-trimethoxybenzoate anion.

C. Weisbecker, A. Attygalle, Sheo B. Singh, 2014, The Journal of organic chemistry.

Platensimycin and platencin congeners from Streptomyces platensis.

Z. Guan, Sheo B. Singh, D. Zink, 2011, Journal of natural products.

Application of time-of-flight mass spectrometry for screening of crude glycerins for toxic phorbol ester contaminants.

R. Reimschuessel, K. Herath, H. Jayasuriya, 2017, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Defensive Chemicals of Two Species of Trachypachus Motschulski

D. Maddison, A. Attygalle, J. Meinwald, 2004, Journal of Chemical Ecology.

Discovery and antibacterial activity of lucensimycin C from Streptomyces lucensis

Ó. Salazar, O. Genilloud, Sheo B. Singh, 2008 .

Dose-dependent effects of siRNA-mediated inhibition of SCAP on PCSK9, LDLR, and plasma lipids in mouse and rhesus monkey[S]

S. Bartz, Shirly Pinto, D. McLaren, 2016, Journal of Lipid Research.

Diterpenoid, steroid, and triterpenoid agonists of liver X receptors from diversified terrestrial plants and marine sources.

Ziqiang Guan, Z. Guan, M. Slattery, 2005, Journal of natural products.

Isolation and structure of antagonists of chemokine receptor (CCR5).

Ziqiang Guan, Z. Guan, D. Stevenson, 2004, Journal of natural products.

New defensive chemical data for ground beetles (Coleoptera: Carabidae): interpretations in a phylogenetic framework

A. Attygalle, K. Will, K. Herath, 2000 .

Tenellones A and B from a Diaporthe sp.: two highly substituted benzophenone inhibitors of parasite cGMP-dependent protein kinase activity.

B. Nare, Z. Guan, P. Liberator, 2005, Journal of natural products.

Development of UHPLC/Q-TOF Analysis Method to Screen Glycerin for Direct Detection of Process Contaminants 3-Monochloropropane-1,2-diol Esters (3-MCPDEs) and Glycidyl Esters (GEs)

R. Reimschuessel, H. Escobar, K. Herath, 2021, Molecules.

The Hepatitis C Virus Core Protein Inhibits Adipose Triglyceride Lipase (ATGL)-mediated Lipid Mobilization and Enhances the ATGL Interaction with Comparative Gene Identification 58 (CGI-58) and Lipid Droplets*

Robert V Farese, Shirly Pinto, R. Zechner, 2014, The Journal of Biological Chemistry.

Defensive production of quinoline by a phasmid insect (Oreophoetes peruana).

T. Eisner, A. Attygalle, J. Meinwald, 1997, The Journal of experimental biology.

Proteome Kinetics: Coupling the Administration of Stable Isotopes with Mass Spectrometry-Based Analyses

D. Johns, T. Roddy, Sheng-ping Wang, 2012 .

Effect of Error Propagation in Stable Isotope Tracer Studies: An Approach for Estimating Impact on Apparent Biochemical Flux.

M. Cleary, D. Johns, Vinit Shah, 2015, Methods in enzymology.

Enhanced data-independent analysis of lipids using ion mobility-TOFMSE to unravel quantitative and qualitative information in human plasma.

Stephen F Previs, Vinit Shah, J. Castro-Pérez, 2013, Rapid communications in mass spectrometry : RCM.

Effects of small interfering RNA-mediated hepatic glucagon receptor inhibition on lipid metabolism in db/db mice[S]

Shirly Pinto, T. Roddy, Kristian K. Jensen, 2013, Journal of Lipid Research.