J. Oppenheimer

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Messenger Rna-S14 as a Model of Thyroid Hormone Action at the Hepatocellular Level

H. Towle, J. Oppenheimer, 1987 .

Rapid effects of triiodothyronine on hepatic gene expression. Hybridization analysis of tissue-specific triiodothyronine regulation of mRNAS14.

D. Jump, P. Narayan, J. Oppenheimer, 1984, The Journal of biological chemistry.

Chromatin structure and methylation state of a thyroid hormone-responsive gene in rat liver.

N. Wong, D. Jump, J. Oppenheimer, 1987, The Journal of biological chemistry.

4 – Distribution and Metabolism of the Thyroid Hormones

J. Oppenheimer, 1990 .

Functional relationship of thyroid hormone-induced lipogenesis, lipolysis, and thermogenesis in the rat.

J. Oppenheimer, J. Lane, M. Thompson, 1991, The Journal of clinical investigation.

Stimulation of hepatic mitochondrial alpha-glycerophosphate dehydrogenase and malic enzyme by L-triiodothyronine. Characteristics of the response with specific nuclear thyroid hormone binding sites fully saturated.

M. Surks, J. Oppenheimer, H. Schwartz, 1977, The Journal of clinical investigation.

Concentration of L-thyroxine and L-triiodothyronine specifically bound to nuclear receptors in rat liver and kidney. Quantitative evidence favoring a major role of T3 in thyroid hormone action.

M. Surks, J. Oppenheimer, 1977, The Journal of clinical investigation.

Replacement dosage of L-thyroxine in hypothyroidism. A re-evaluation.

M. Surks, J. Oppenheimer, J. Stock, 1974, The New England journal of medicine.

Comparison of effectiveness of thyrotropin-suppressive doses of D- and L-thyroxine in treatment of hypercholesterolemia.

D. Hunninghake, C. Mariash, J. Bantle, 1984, The American journal of medicine.

Interaction of thyroid hormone and nutritional signals on thyroid hormone action

C. Mariash, J. Oppenheimer, 1985, Molecular and Cellular Endocrinology.

Hepatic messenger ribonucleic acid activity profile of rats subjected to alterations in thyroidal and adrenocortical states: evidence for significant interaction.

C. Mariash, F. Carr, J. Oppenheimer, 1985, Endocrinology.

Common clinical indices of thyroid hormone action: relationships to serum free 3,5,3'-triiodothyronine concentration and estimated nuclear occupancy.

G. Runger, J. Bantle, J. Oppenheimer, 1980, The Journal of clinical endocrinology and metabolism.

Hepatic messenger ribonucleic acid activity profiles in experimental azotemia in the rat. Relationship to food intake and thyroid function.

C. Mariash, F. Carr, W. Kinlaw, 1984, The Journal of clinical investigation.

Stimulation of S14 mRNA and lipogenesis in brown fat by hypothyroidism, cold exposure, and cafeteria feeding: evidence supporting a general role for S14 in lipogenesis and lipogenesis in the maintenance of thermogenesis.

H. Freake, J. Oppenheimer, 1987, Proceedings of the National Academy of Sciences of the United States of America.

Hepatic accumulation of 125I-thyroxine in the rat: augmentation by phenobarbital and chlordane.

J. Oppenheimer, G. Bernstein, S. Artz, 1968, Endocrinology.

Triiodothyronine-stimulated formation of poly(A)-containing nuclear RNA and mRNA in rat liver.

J. Oppenheimer, W. Dillmann, H. Schwartz, 1978, Endocrinology.

Quantitation of rat liver messenger ribonucleic acid for malic enzyme during induction by thyroid hormone.

H. Towle, C. Mariash, J. Oppenheimer, 1981, Biochemistry.

Changes in the hepatic levels of messenger ribonucleic acid for malic enzyme during induction by thyroid hormone or diet.

H. Towle, C. Mariash, J. Oppenheimer, 1980, Biochemistry.

Association of thyroid hormone receptors with chromatin

D. Jump, J. Oppenheimer, 2004, Molecular and Cellular Biochemistry.

Thyroid hormone action at the nuclear level.

J. Oppenheimer, 1985, Annals of internal medicine.

Association of the thyroid hormone receptor with rat liver chromatin.

D. Jump, J. Oppenheimer, S. Seelig, 1981, Biochemistry.

Thyroid hormone receptor-containing fragment released from chromatin by deoxyribonuclease I and micrococcal nuclease.

D. Jump, J. Oppenheimer, 1980, Science.

Comparison of the response characteristics of four lipogenic enzymes to 3,5,3'-triiodothyronine administration: evidence for variable degrees of amplification of the nuclear 3,5,3'-triiodothyronine signal.

C. Mariash, F. Kaiser, J. Oppenheimer, 1980, Endocrinology.

Partial purification of the triiodothyronine receptor from rat liver nuclei. Differences in the chromatographic mobility of occupied and unoccupied sites.

J. Oppenheimer, H. Astier, H. Schwartz, 1977, The Journal of biological chemistry.

Stimulation of malic enzyme formation in hepatocyte culture by metabolites: evidence favoring a nonglycolytic metabolite as the proximate induction signal.

C. Mariash, J. Oppenheimer, 1984, Metabolism: clinical and experimental.

9 – Thyroid Hormone–Carbohydrate Interaction

C. Mariash, J. Oppenheimer, 1983 .

Synergism of thyroid hormone and high carbohydrate diet in the induction of lipogenic enzymes in the rat. Mechanisms and implications.

H. Towle, C. Mariash, F. Kaiser, 1980, The Journal of clinical investigation.

Molecular mechanisms at the tissue level in hyperthyroidism.

J. Oppenheimer, W. Dillmann, 1978, Clinics in endocrinology and metabolism.

Comparison of age-related decreases in the basal and carbohydrate inducible levels of lipogenic enzymes in adipose tissue and liver.

C. Mariash, F. Kaiser, J. Oppenheimer, 1983, Metabolism: clinical and experimental.

Decreased serum triiodothyronine in starving rats is due primarily to diminished thyroidal secretion of thyroxine.

W. Kinlaw, J. Oppenheimer, H. Schwartz, 1985, The Journal of clinical investigation.

In vitro binding of L-triiodothyronine to receptors in rat liver nuclei. Kinectics of binding, extraction properties, and lack of requirement for cytosol proteins.

M. Surks, J. Oppenheimer, D. Koerner, 1975, The Journal of clinical investigation.

Dissociation between thyroxine metabolism and hormonal action in phenobarbital-treated rats.

M. Surks, J. Oppenheimer, H. Schwartz, 1971, Endocrinology.

Advances in our understanding of thyroid hormone action at the cellular level.

N. Wong, H. Freake, C. Mariash, 1987, Endocrine reviews.

Quantitative aspects of iodothyronine binding by cytosol proteins of rat liver and kidney.

M. Surks, J. Oppenheimer, W. Dillman, 1974, Endocrinology.

Opposing effects of glucagon and triiodothyronine on the hepatic levels of messenger ribonucleic acid S14 and the dependence of such effects on circadian factors.

H. Towle, W. Kinlaw, J. Oppenheimer, 1986, The Journal of clinical investigation.

[47] Methods for determining the conversion of l-thyroxine (T4) to l-triiodothyronine (T3)

M. Surks, J. Oppenheimer, 1975 .

Transcellular and transnuclear transport of 3,5,3'-triiodothyronine in isolated hepatocytes.

C. Mariash, A. Mooradian, J. Oppenheimer, 1985, Endocrinology.

Determination of iodothyronine absorption and conversion of L-thyroxine (T 4 ) to L-triiodothyronine (T 3 ) using turnover rate techniques.

M. Surks, J. Oppenheimer, J. Stock, 1973, The Journal of clinical investigation.

Thyroid hormone action at the cellular level.

J. Oppenheimer, 1979, Science.

Letter: (to the editor). Erratum: revised calculations of common parameters of iodothyronine metabolism and distribution by noncompartmental analysis.

M. Surks, J. Oppenheimer, H. Schwartz, 1975, The Journal of clinical endocrinology and metabolism.

Determination of common parameters fo iodothyronine metabolism and distribution in man by noncompartmental analysis.

M. Surks, J. Oppenheimer, H. Schwartz, 1975, The Journal of clinical endocrinology and metabolism.

Propylthiouracil inhibits the conversion of L-thyroxine to L-triiodothyronine. An explanation of the antithyroxine effect of propylthiouracil and evidence supporting the concept that triiodothyronine is the active thyroid hormone.

M. Surks, J. Oppenheimer, H. Schwartz, 1972, The Journal of clinical investigation.

Replacement dose, metabolism, and bioavailability of levothyroxine in the treatment of hypothyroidism. Role of triiodothyronine in pituitary feedback in humans.

J. Cavanaugh, L. Fish, J. Bantle, 1987, The New England journal of medicine.

Estimation of rapidly exchangeable cellular thyroxine from the plasma disappearance curves of simultaneously administered thyroxine-131-I and albumin-125-I.

J. Oppenheimer, G. Bernstein, J. Hasen, 1967, The Journal of clinical investigation.

Levothyroxine dose requirements for thyrotropin suppression in the treatment of differentiated thyroid cancer.

C. Mariash, L. Burmeister, J. Oppenheimer, 1992, The Journal of clinical endocrinology and metabolism.

Isoform-specific 3,5,3'-triiodothyronine receptor binding capacity and messenger ribonucleic acid content in rat adenohypophysis: effect of thyroidal state and comparison with extrapituitary tissues.

J. Oppenheimer, H. Schwartz, S. Ercan-Fang, 1996, Endocrinology.

Triiodothyronine nuclear binding capacity in rat tissues correlates with a 6.0 kilobase (kb) and not a 2.6 kb messenger ribonucleic acid hybridization signal generated by a human c-erbA probe.

H. Freake, J. Oppenheimer, H. Schwartz, 1988, Molecular endocrinology.

Response to thyrotropin releasing hormone: an objective criterion for the adequacy of thyrotropin suppression therapy.

M. Surks, E. Weitzman, J. Oppenheimer, 1977, The Journal of clinical endocrinology and metabolism.

Time course of hepatic 3-hydroxy-3-methylglutaryl coenzyme A reductase activity and messenger ribonucleic acid, biliary lipid secretion, and hepatic cholesterol content in methimazole-treated hypothyroid and hypophysectomized rats after triiodothyronine administration: possible linkage of cholestero

K. Strait, R. Day, R. Gebhard, 1989, Endocrinology.

Relationship of c-erbA mRNA content to tissue triiodothyronine nuclear binding capacity and function in developing and adult rats.

K. Strait, J. Oppenheimer, A. Pérez-Castillo, 1990, The Journal of biological chemistry.

Comparison of the metabolism and distribution of L-triiodothyronine and triiodothyroacetic acid in the rat: a possible explanation of differential hormonal potency.

M. Surks, J. Oppenheimer, B. Goslings, 1976, Endocrinology.

Nuclear receptors and the initiation of thyroid hormone action.

M. Surks, J. Oppenheimer, W. Dillmann, 1976, Recent progress in hormone research.

Limited binding capacity sites for L-triiodothyronine in rat liver nuclei. Nuclear-cytoplasmic interrelation, binding constants, and cross-reactivity with L-thyroxine.

M. Surks, J. Oppenheimer, H. Schwartz, 1974, The Journal of clinical investigation.

Specific nuclear triiodothyronine binding sites in rat liver and kidney.

M. Surks, J. Oppenheimer, H. Schwartz, 1972, The Journal of clinical endocrinology and metabolism.

Prolonged fasting reduces rat hepatic beta 1 thyroid hormone receptor protein without changing the level of its messenger ribonucleic acid.

K. Strait, J. Oppenheimer, J. Lane, 1991, Endocrinology.

6 – Measurement of Thyroid Function

J. Oppenheimer, R. Volpe, 1990 .

Starvation and hypothyroidism exert an overlapping influence on rat hepatic messenger RNA activity profiles.

C. Mariash, F. Carr, J. Oppenheimer, 1983, The Journal of clinical investigation.

Factors determining the level of activity of 3,5,3'-triiodothyronine-responsive hepatic enzymes in the starved rat.

J. Oppenheimer, H. Schwartz, H. L. Schwartz, 1980, Endocrinology.

Binding of selected iodothyronine analogues to receptor sites of isolated rat hepatic nuclei. High correlation between structural requirements for nuclear binding and biological activity.

M. Surks, J. Oppenheimer, H. Schwartz, 1975, The Journal of biological chemistry.

Nuclear binding capacity appears to limit the hepatic response to L-triiodothyronine (T3).

M. Surks, J. Oppenheimer, H. Schwartz, 1975, Endocrine research communications.

Tissue differences in the concentration of triiodothyronine nuclear binding sites in the rat: liver, kidney, pituitary, heart, brain, spleen, and testis.

M. Surks, J. Oppenheimer, H. Schwartz, 1974, Endocrinology.

In vitro demonstration of specific triiodothyronine binding sites in rat liver nuclei.

M. Surks, J. Oppenheimer, D. Koerner, 1974, The Journal of clinical endocrinology and metabolism.

Effect of thyroid hormone analogues on the displacement of 125I-L-triiodothyronine from hepatic and heart nuclei in vivo: possible relationship to hormonal activity.

M. Surks, J. Oppenheimer, H. Schwartz, 1973, Biochemical and biophysical research communications.

Limited capacity binding sites for L-triiodothyronine in rat liver nuclei. Localization to the chromatin and partial characterization of the L-triiodothyronine-chromatin complex.

M. Surks, J. Oppenheimer, D. Koerner, 1973, The Journal of biological chemistry.

Specific Triiodothyronine Binding Sites in the Anterior Pituitary of the Rat

M. Surks, J. Oppenheimer, H. Schwartz, 1972, Science.

Selective alterations in hepatic enzyme response after reduction of nuclear triiodothyronine receptor sites by partial hepatectomy and starvation.

J. Oppenheimer, W. Dillmann, H. Schwartz, 1978, Biochemical and biophysical research communications.

Glucagon administration decreases hepatic nuclear triiodothyronine binding capacity.

J. Oppenheimer, W. Dillmann, R. A. Bonner, 1978, Endocrinology.

Tissue iodoprotein formation during the peripheral metabolism of the thyroid hormones.

M. Surks, J. Oppenheimer, H. Schwartz, 1969, The Journal of clinical investigation.

Nuclear triiodothyronine receptor sites in brain: probable identity with hepatic receptors and regional distribution.

J. Oppenheimer, H. Schwartz, H. L. Schwartz, 1978, Endocrinology.

Endocrine Manifestations of Intracranial Extrasellar Lesions

H. Lebovitz, L. Kahana, J. Oppenheimer, 1962 .

Rapid synergistic interaction between thyroid hormone and carbohydrate on mRNAS14 induction.

C. Mariash, J. Oppenheimer, S. Seelig, 1986, The Journal of biological chemistry.

Transient stimulation of myelin basic protein gene expression in differentiating cultured oligodendrocytes: a model for 3,5,3'-triiodothyronine-induced brain development.

K. Strait, J. Oppenheimer, H. Schwartz, 1997, Endocrinology.

Thyroid hormone receptor isoform content in cultured type 1 and type 2 astrocytes.

Strait, K. Strait, L., 1996, Endocrinology.

Nonlinear (amplified) relationship between nuclear occupancy by triiodothyronine and the appearance rate of hepatic alpha-glycerophosphate dehydrogenase and malic enzyme in the rat.

P. Coulombe, J. Oppenheimer, H. Schwartz, 1978, The Journal of clinical investigation.

Distribution and metabolism of L- and D-triiodothyronine (T3) in the rat: preferential accumulation of L-T3 by hepatic and cardiac nuclei as a probable explanation of the differential biological potency of T3 enantiomers.

D. Jump, N. Jiang, D. Trence, 1983, Endocrinology.

Role of plasma proteins in the binding, distribution and metabolism of the thyroid hormones.

J. Oppenheimer, 1968, The New England journal of medicine.

Two unusual variants of Nelson's syndrome.

J. Oppenheimer, K. Mukai, R. A. Bonner, 1979, The Journal of clinical endocrinology and metabolism.

Depression of the serum protein-bound iodine level by diphenylhydantion.

K. M. Nelson, J. Oppenheimer, J. W. Jailer, 1961, The Journal of clinical endocrinology and metabolism.

Triiodothyronine rapidly reverses inhibition of S14 gene transcription by glucagon.

C. Mariash, P. Hamblin, W. Kinlaw, 1988, Endocrinology.

1 – The Nuclear Receptor–Triiodothyronine Complex: Relationship to Thyroid Hormone Distribution, Metabolism, and Biological Action

J. Oppenheimer, 1983 .

Nuclear Receptors for Triiodothyronine: A Physiological Perspective

J. Oppenheimer, W. Dillmann, 1978 .

The peripheral action of the thyroid hormones.

M. Surks, J. Oppenheimer, 1975, The Medical clinics of North America.

Quantitation of extrathyroidal conversion of L-thyroxine to 3,5,3'-triiodo-L-thyronine in the rat.

M. Surks, J. Oppenheimer, H. Schwartz, 1971, The Journal of clinical investigation.

The regulation of lipogenesis by thyroid hormone and its contribution to thermogenesis.

H. Freake, J. Oppenheimer, H. Schwartz, 1989, Endocrinology.

Thyroid hormone-carbohydrate interaction in the rat: correlation between age-related reductions in the inducibility of hepatic malic enzyme by triiodo-L-thyronine and a high carbohydrate, fat-free diet.

H. Towle, C. Mariash, M. Forciea, 1981, The Journal of clinical investigation.

Nuclear receptors for 3,5,3'-triiodothyronine in human liver and kidney: characterization, quantitation, and similarities to rat receptors.

J. Oppenheimer, H. Schwartz, L. Schuster, 1979, The Journal of clinical endocrinology and metabolism.

Interaction of Thyroid Hormone and Carbohydrates on Hepatic Gene Expression

H. Freake, C. Mariash, W. Kinlaw, 1987 .

Stereospecific transport of triiodothyronine from plasma to cytosol and from cytosol to nucleus in rat liver, kidney, brain, and heart.

J. Oppenheimer, H. Schwartz, 1985, The Journal of clinical investigation.

BINDING OF THYROXINE BY SERUM PROTEINS EVALUATED BY EQUILIBRUM DIALYSIS AND ELECTROPHORETIC TECHNIQUES. ALTERATIONS IN NONTHYROIDAL ILLNESS.

M. Surks, J. Oppenheimer, R. Squef, 1963, The Journal of clinical investigation.

CHAPTER 33 – Abnormalities of Neuroendocrine Functions in Man

J. Oppenheimer, 1967 .

Replacement Treatment of Hypothyroidism

M. Surks, D. Koutras, J. Hamburger, 1974 .

Dissociation of hepatic messenger ribonucleic acidS14 levels and nuclear transcriptional rates in suckling rats.

H. Towle, D. Jump, J. Oppenheimer, 1986, Endocrinology.

C. Mariash, M. Forciea, J. Oppenheimer, 1979, Endocrinology.

Ontogenesis of 3,5,3'-triiodothyronine receptors in neonatal rat brain: dissociation between receptor concentration and stimulation of oxygen consumption by 3,5,3'-triiodothyronine.

J. Oppenheimer, H. Schwartz, Harold L. Schwartz, 1978, Endocrinology.

Interaction of T3 and carbohydrate in the induction of lipogenic enzymes.

H. Towle, C. Mariash, F. Kaiser, 1981, Life sciences.

Relationship between the accumulation of pituitary growth hormone and nuclear occupancy by triiodothyronine in the rat.

P. Coulombe, J. Oppenheimer, H. Schwartz, 1978, The Journal of clinical investigation.

Interactions of thyroid hormone, growth hormone, and high carbohydrate, fat-free diet in regulating several rat liver messenger ribonucleic acid species.

H. Towle, C. Mariash, J. Oppenheimer, 1983, Biochemistry.

Lack of Effect of Thyroid Hormone on Late Fetal Rat Brain Development*

M. Ross, J. Oppenheimer, H. Schwartz, 2022 .

Analysis of the rapid interchange of thyroxine between plasma and liver and plasma and kidney in the intact rat.

J. Oppenheimer, G. Bernstein, J. Hasen, 1968, Endocrinology.

DETERMINATION OF FREE THYROXINE IN HUMAN SERUM: A THEORETICAL AND EXPERIMENTAL ANALYSIS.

M. Surks, J. Oppenheimer, 1964, The Journal of clinical endocrinology and metabolism.

Difference between thyroidectomized and hypophysectomized animals in their hepatic ribonucleic acid response to thyroid hormone.

H. Towle, J. Oppenheimer, H. Schwartz, 1980, Endocrinology.

Interrelationship of triiodothyronine concentration, metabolism, protein binding, and nuclear occupancy in the induction of malic enzyme by cultured adult rat hepatocytes.

C. Mariash, J. Oppenheimer, 1983, Endocrinology.

Inhibition of malic enzyme induction by triiodothyronine in the diabetic rat: reversal by fructose feeding.

C. Mariash, F. Kaiser, J. Oppenheimer, 1980, Metabolism: clinical and experimental.

Metabolism of Iodine-131-Labeled Thyroxine-Binding Prealbumin in Man

M. Surks, J. Oppenheimer, J. C. Smith, 1965, Science.

Differences in antibody recognition of the triiodothyronine nuclear receptor and c-erbA products.

H. Freake, J. Ghysdael, Y. Goldberg, 1988, Molecular endocrinology.

High basal expression and 3,5,3'-triiodothyronine regulation of messenger ribonucleic acid S14 in lipogenic tissues.

D. Jump, J. Oppenheimer, 1985, Endocrinology.

Glucose and triiodothyronine both induce malic enzyme in the rat hepatocyte culture: evidence that triiodothyronine multiplies a primary glucose-generated signal.

H. Towle, C. Mariash, J. Oppenheimer, 1981, The Journal of clinical investigation.

A therapeutic controversy. Thyroid hormone treatment: when and what?

P. Ladenson, L. Braverman, A. Toft, 1995, The Journal of clinical endocrinology and metabolism.

Immunocytochemical delineation of thyroid hormone receptor beta 2-like immunoreactivity in the rat central nervous system.

M. Lazar, K. Strait, J. Oppenheimer, 1993, Endocrinology.

INTERACTION OF DRUGS WITH THYROID HORMONE BINDING SITES *

J. Oppenheimer, 1973, Annals of the New York Academy of Sciences.

Distribution of thyroid hormone-responsive translated products in rat liver polysome and postribosomal ribonucleoprotein populations.

D. Jump, F. Carr, J. Oppenheimer, 1984, Endocrinology.

Labile proteins are necessary for T3 induction of growth hormone mRNA in normal rat pituitary and rat pituitary tumor cells.

N. Wong, J. Oppenheimer, A. Pérez-Castillo, 1987, The Journal of biological chemistry.

Triiodothyronine regulation of multiple rat hepatic genes: requirement for ongoing protein synthesis.

N. Wong, P. Hamblin, J. Oppenheimer, 1987, Molecular endocrinology.

Thyroid hormone attenuates and augments hepatic gene expression at a pretranslational level.

H. Towle, J. Oppenheimer, C. Liaw, 1981, Proceedings of the National Academy of Sciences of the United States of America.

Thyroidectomy increases rat hepatic ferritin iron.

H. Towle, C. Mariash, J. Oppenheimer, 1981, Science.

Slow fractional removal of nonextractable iodine from rat tissue after injection of labeled L-thyroxine and 3,5,3'-triiodo-L-thyronine. A possible clue to the mechanism of initiation and persistence of hormonal action.

M. Surks, J. Oppenheimer, H. Schwartz, 1972, The Journal of clinical investigation.

In vitro formation of apparent covalent complexes between L-triiodothyronine and plasma protein.

M. Surks, J. Oppenheimer, D. Koerner, 1973, The Journal of clinical endocrinology and metabolism.

Formation of nondissociable hormone-protein complexes during the in vitro incubation of L-thyroxine and 3,5,3'-triiodo-L-thyronine with hepatic microsomes.

M. Surks, J. Oppenheimer, V. Kozyreff, 1971, Endocrinology.

Composition of nonextractable radioactivity formed after injection of labeled L-thyroxine and 3,5,3'-triiodo-L-thyronine in rats.

M. Surks, J. Oppenheimer, 1970, Endocrinology.

High incidence of decreased serum triiodothyronine concentration in patients with nonthyroidal disease.

M. Surks, F. Bermúdez, J. Oppenheimer, 1975, The Journal of clinical endocrinology and metabolism.

Quantitative assessment of pituitary resistance to thyroid hormone from plots of the logarithm of thyrotropin versus serum free thyroxine index.

C. Mariash, J. Oppenheimer, H. Schwartz, 2000, The Journal of clinical endocrinology and metabolism.

The metabolic significance of exchangeable cellular thyroxine.

M. Surks, J. Oppenheimer, H. Schwartz, 1969, Recent progress in hormone research.

Beta receptor isoforms are not essential for thyroid hormone-dependent acceleration of PCP-2 and myelin basic protein gene expression in the developing brains of neonatal mice

D. Forrest, C. Mariash, J. Oppenheimer, 1998, Molecular and Cellular Endocrinology.

Molecular basis of thyroid hormone-dependent brain development.

J. Oppenheimer, H. Schwartz, Jack H. Oppenheimer, 1997, Endocrine reviews.

Evidence for a factor in the sera of patients with nonthyroidal disease which inhibits iodothyronine binding by solid matrices, serum proteins, and rat hepatocytes.

C. Mariash, F. Kaiser, J. Oppenheimer, 1982, The Journal of clinical endocrinology and metabolism.

Use of the dexamethasone-adrenocorticotropin test to assess the requirement for continued glucocorticoid replacement therapy after pituitary surgery.

C. Mariash, J. Bantle, J. Oppenheimer, 1985, The Journal of clinical endocrinology and metabolism.

Thyroid hormones influence starvation-induced hepatic protein loss in the rat: possible role of thyroid hormones in the generation of labile protein.

J. Oppenheimer, H. Schwartz, S. Lancer, 1980, Endocrinology.

Physiologic and biochemical actions of thyroid hormone.

J. Oppenheimer, H. Schwartz, Harold L. Schwartz, 1978, Pharmacology & therapeutics. Part B: General & systematic pharmacology.

Breast cancer and thyroid therapy. Statement by the American Thyroid Association.

R. Rivlin, C. Gorman, J. Robbins, 1977, JAMA.

A rapid, inexpensive, quantitative technique for the analysis of two-dimensional electrophoretograms.

C N Mariash, S Seelig, J H Oppenheimer, 1982, Analytical biochemistry.

Evidence for post-transcriptional effects of T3 on hepatic ferritin synthesis.

C. Mariash, D. Jump, J. Oppenheimer, 1982, Biochemical and biophysical research communications.

5 – Tissue and Cellular Effects of Thyroid Hormones and Their Mechanism of Action

J. Oppenheimer, 1990 .

Glucagon influences the expression of thyroid hormone action: discrepancy between nuclear triiodothyronine receptor number and enzyme responses.

J. Oppenheimer, W. Dillmann, 1979, Endocrinology.

Studies on the thyroxine-diphenylhydantoin interaction: effect of 5,5'-diphenylhydantoin on the displacement of L-thyroxine from thyroxine-binding globulin (TBG).

J. Oppenheimer, R. Tavernetti, 1962, Endocrinology.

Thermogenesis and thyroid function.

H. Freake, J. Oppenheimer, J. H. Oppenheimer, 1995, Annual review of nutrition.

Immunofluorescent localization of thyroid hormone receptor isoforms in glial cells of rat brain.

K. Strait, J. Oppenheimer, H. Schwartz, 1994, Endocrinology.

TSH response to TRH in euthyroid, hypercholesterolemic patients treated with graded doses of dextrothyroxine.

D. Hunninghake, J. Probstfield, J. Bantle, 1981, Metabolism: clinical and experimental.

A new radioimmunoassay for plasma L-triiodothyronine: measurements in thyroid disease and in patients maintained on hormonal replacement.

J H Oppenheimer, M. Surks, M I Surks, 1972, The Journal of clinical investigation.

Formation of iodoprotein during the peripheral metabolism of 3,5,3'-triiodo-L-thyronine-125I in the euthyroid man and rat.

M. Surks, J. Oppenheimer, 1969, The Journal of clinical investigation.

An analysis of the interrelationship of nuclear and plasma triiodothyronine in the sea lamprey, lake trout, and rat: evolutionary considerations.

J. Oppenheimer, H. Schwartz, R. Weirich, 1987, Endocrinology.

LETTER TO THE EDITOR: Turnover of 131I-Thyroxine in Patients Subjected to Surgical Trauma1

J. Oppenheimer, G. Bernstein, J. Hasen, 1967 .

Factors influencing the concentration of free and total thyroxine in patients with nonthyroidal disease.

J. Oppenheimer, G. Bernstein, 1966, The Journal of clinical endocrinology and metabolism.

POSTOPERATIVE CHANGES IN THE CONCENTRATION OF THYROXINE-BINDING PREALBUMIN AND SERUM FREE THYROXINE.

M. Surks, J. Oppenheimer, 1964, The Journal of clinical endocrinology and metabolism.

Displacement of thyroxine from human thyroxine-binding globulin by analogues of hydantoin. Steric aspects of the thyroxinebinding site.

J. Oppenheimer, R. Tavernetti, 1962, The Journal of clinical investigation.

Differences in primary cellular factors influencing the metabolism and distribution of 3,5,3'-L-triiodothyronine and L-thyroxine.

M. Surks, J. Oppenheimer, H. Schwartz, 1970, The Journal of clinical investigation.

Nuclear receptors and thyroid hormone action: a progress report.

H. Towle, J. Oppenheimer, W. Dillmann, 1979, Federation proceedings.

Molecular Basis of Thyroid Hormone Action

H. Samuels, J. Oppenheimer, J. Apriletti, 1983 .

Widespread distribution of immunoreactive thyroid hormone beta 2 receptor (TR beta 2) in the nuclei of extrapituitary rat tissues.

M. Lazar, J. Oppenheimer, H. Schwartz, 1994, The Journal of biological chemistry.

American Thyroid Association statement on breast cancer and thyroid hormone therapy.

R. Rivlin, C. Gorman, J. Robbins, 1977, American journal of surgery.

A purkinje cell protein-2 intronic thyroid hormone response element binds developmentally regulated thyroid hormone receptor-nuclear protein complexes

K. Strait, J. Oppenheimer, R. Larson, 2007, Journal of Molecular Neuroscience.

Evolving concepts of thyroid hormone action.

J. Oppenheimer, 1999, Biochimie.

Kinetics of induction by thyroid hormone of the two hepatic mRNAs coding for cytosolic malic enzyme in the hypothyroid and euthyroid states. Evidence against an obligatory role of S14 protein in malic enzyme gene expression.

K. Strait, C. Mariash, W. Kinlaw, 1989, The Journal of biological chemistry.

T3 stimulates the synthesis of a specific mRNA in primary hepatocyte culture.

C. Mariash, D. Jump, J. Oppenheimer, 1984, Biochemical and biophysical research communications.

Thyroid hormone-, carbohydrate, and age-dependent regulation of a methylation site in the hepatic S14 gene.

N. Wong, K. Strait, J. Oppenheimer, 1989, Molecular endocrinology.

Rat hepatic mRNA-S14 and lipogenic enzymes during weaning: role of S14 in lipogenesis.

J. Oppenheimer, A. Pérez-Castillo, H. Schwartz, 1987, The American journal of physiology.

Interaction of dietary carbohydrate and glucagon in regulation of rat hepatic messenger ribonucleic acid S14 expression: role of circadian factors and 3',5'-cyclic adenosine monophosphate.

C. Mariash, L. Fish, W. Kinlaw, 1987, Molecular endocrinology.

Quantitative investigation of hepatic genomic response to hormonal and pathophysiological stimuli by multivariate analysis of two-dimensional mRNA activity profiles.

C. Mariash, C. Kistner, F. Carr, 1984, Proceedings of the National Academy of Sciences of the United States of America.

A pituitary parasellar tumor with extracranial metastases and high, partially suppressible levels of adrenocorticotropin and related peptides.

D. Orth, F. Kaiser, J. Oppenheimer, 1983, The Journal of clinical endocrinology and metabolism.

American thyroid association statement: breast cancer and thyroid hormone therapy.

R. Rivlin, C. Gorman, J. Robbins, 1977, Annals of internal medicine.

Effects of triiodothyronine and glucose on cultured rat hepatocyte gene expression.

C. Mariash, D. Topliss, F. Carr, 1983, Endocrinology.

Paradoxical effects of cycloheximide on the ultra-rapid induction of two hepatic mRNA sequences by triiodothyronine (T3).

H. Towle, C. Mariash, D. Jump, 1982, Endocrinology.

Resistance to Thyroid Hormones: A Disorder Frequently Confused With Graves' Disease

C. Mariash, J. Bantle, R. Ulstrom, 1982 .

ATA statement on breast cancer and thyroid hormone therapy.

R. Rivlin, C. Gorman, J. Robbins, 1977, The Journal of pediatrics.

Increased thyroxine turnover and thyroidal function after stimulation of hepatocellular binding of thyroxine by phenobarbital.

M. Surks, J. Oppenheimer, G. Bernstein, 1968, The Journal of clinical investigation.

Effect of prednisone on thyroxine-binding proteins.

J. Oppenheimer, S. Werner, JACK H. Oppenheimer, 1966, The Journal of clinical endocrinology and metabolism.

The laboratory evaluation of thyroid function.

M. Steffes, J. Oppenheimer, 1979, Minnesota medicine.

Messenger RNA content and complexity of euthyroid and hypothyroid rat liver.

H. Towle, J. Oppenheimer, W. Dillmann, 1979, The Journal of biological chemistry.

Use of Thyroxine-Displacing Drugs in Identifying Serum Thyroxine-Binding Proteins Separated by Starch Gel Electrophoresis.∗

J. Oppenheimer, R. Squef, M. Martinez, 1963, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.

Chicken Ovalbumin Upstream Promoter-Transcription Factor (COUP-TF) Modulates Expression of the Purkinje Cell Protein-2 Gene

C. Mariash, G. Anderson, J. Oppenheimer, 1998, The Journal of Biological Chemistry.

Identification of thyroid hormone response elements in rodent Pcp-2, a developmentally regulated gene of cerebellar Purkinje cells.

K. Strait, J. Oppenheimer, L. Zou, 1994, The Journal of biological chemistry.

Abnormalities of Thyroxine Binding in Analbuminemia1

J. Oppenheimer, C. Hollander, G. Bernstein, 1968 .

Abnormalities of thyroxine binding in analbuminemia.

J. Oppenheimer, C. Hollander, G. Bernstein, 1968, The Journal of clinical endocrinology and metabolism.

Incomplete suppression of thyrotropin secretion after single injection of large L-triiodothyronine doses into hypothyroid rats.

M. Surks, J. Oppenheimer, 1976, Endocrinology.

Acromegaly: reassessment of the long-term therapeutic effectiveness of transsphenoidal pituitary surgery.

J. Bantle, J. Oppenheimer, E. Seljeskog, 1981, Annals of internal medicine.

Free fatty acids: a possible regulator of free thyroid hormone levels in man.

T. Merimee, J. Oppenheimer, C. Hollander, 1967, The Journal of clinical endocrinology and metabolism.

Determination of the maximal binding capacity and protein concentration of thyroxine-binding prealbumin in human serum.

J. Oppenheimer, G. Bernstein, M. Martinez, 1966, The Journal of laboratory and clinical medicine.

An unsolved problem. Low serum PBI values in patients with chronic disease.

J H Oppenheimer, J. Oppenheimer, 1969, Journal of chronic diseases.

Heparin administration appears to decrease cellular binding of thyroxine.

M. Surks, D. Faierman, J. Oppenheimer, 1973, The Journal of clinical endocrinology and metabolism.

Thyroid hormones in liver.

J. Oppenheimer, 1972, Mayo Clinic proceedings.

ISOLATION AND CHARACTERIZATION OF HUMAN THYROXINE-BINDING PREALBUMIN.

M. Surks, J. Oppenheimer, J. C. Smith, 1965, The Journal of biological chemistry.

Multihormonal regulation and kinetics of induction of a hepatic mRNA sequence which is slowly responsive to triiodothyronine.

N. Wong, J. Oppenheimer, 1986, The Journal of biological chemistry.

Revised nomenclature for tests of thyroid hormones and thyroid-related proteins in serum.

P. Larsen, C. Mariash, J. Hershman, 1987, The Journal of clinical endocrinology and metabolism.

Diurnal variation in hepatic expression of the rat S14 gene is synchronized by the photoperiod.

L. Fish, W. Kinlaw, J. Oppenheimer, 1987, Endocrinology.

Morphological and functional studies of thyroid tissue cultures.

J. Tata, R. W. Rawson, J. Oppenheimer, 1956, Experimental cell research.

Kinetic model of the response of precursor and mature rat hepatic mRNA-S14 to thyroid hormone.

C. Mariash, J. Oppenheimer, H. Schwartz, 1994, The American journal of physiology.

Effect of Thyroid Hormone on the Ploidy of Rat Liver Nuclei as Determined by Flow-Cytometry

L. Koss, R. Wolley, J. Oppenheimer, 1978, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.

Thyroid hormone action 1994: the plot thickens.

K. Strait, J. Oppenheimer, H. Schwartz, 1994, European Journal of Endocrinology.

Beta 1 isoform-specific regulation of a triiodothyronine-induced gene during cerebellar development.

K. Strait, J. Oppenheimer, L. Zou, 1992, Molecular endocrinology.

Molecular mechanisms of thyroid hormone action. A physiologic perspective.

K. Strait, J. Oppenheimer, H. Schwartz, 1993, Clinics in laboratory medicine.

Purkinje cell protein-2 cis-elements mediate repression of T3-dependent transcriptional activation

K. Strait, C. Mariash, G. Anderson, 1997, Molecular and Cellular Endocrinology.

CHAPTER 5 – Biochemical Basis of Thyroid Hormone Action

M. Surks, J. Oppenheimer, 1975 .

Radioiodinated impurities in commercial preparations of 131-I-thyroxine and their effect on the measurement of free thyroxine in human serum by equilibrium dialysis.

J. Oppenheimer, E. Volpert, M. Martinez, 1967, The Journal of clinical endocrinology and metabolism.

Disturbance of the pituitary-adrenal interrelationship in diseases of the central nervous system.

J. Oppenheimer, J. W. Jailer, L. V. Fisher, 1961, The Journal of clinical endocrinology and metabolism.

Bone minerals and levothyroxine. Authors' replies

L. Hegedüs, C. Mariash, P. Schneider, 1992 .

Identification of rat S14 protein and comparison of its regulation with that of mRNA S14 employing synthetic peptide antisera.

N. Ling, W. Kinlaw, J. Oppenheimer, 1989, The Journal of biological chemistry.

Increased Deiodination of L-Thyroxine and L-Triiodothyronine by Liver Microsomes from Rats treated with Phenobarbital

M. Surks, J. Oppenheimer, H. Schwartz, 1969, Nature.

Effect of phenobarbital administration on the subcellular distribution of 125-I-thyroxine in rat liver: mportance of microsomal binding.

J. Oppenheimer, H. Schwartz, G. Bernstein, 1969, Endocrinology.

Quantitation of rat tissue thyroid hormone binding receptor isoforms by immunoprecipitation of nuclear triiodothyronine binding capacity.

N. Ling, K. Strait, J. Oppenheimer, 1992, The Journal of biological chemistry.

Effect of thyroid hormones and high carbohydrate feeding on gene expression in rat epididymal adipose tissue.

H. Freake, C. Mariash, J. Oppenheimer, 1987, Endocrinology.

Triiodothyronine-Induced Gene during Cerebellar Development

K. Strait, J. Oppenheimer, L. Zou, 1992 .

Immunofluorescence localization of thyroid hormone receptor protein beta 1 and variant alpha 2 in selected tissues: cerebellar Purkinje cells as a model for beta 1 receptor-mediated developmental effects of thyroid hormone in brain.

N. Ling, K. Strait, J. Oppenheimer, 1991, Proceedings of the National Academy of Sciences of the United States of America.

Cycloheximide inhibits S-14 gene transcription and abolishes DNase I hypersensitive S-14 sites in the livers of euthyroid but not hypothyroid rats.

N. Wong, J. Oppenheimer, H. Schwartz, 1987, Molecular Endocrinology.

Pituitary tumor with primary hypothyroidism. Possible etiologic relationship.

J. Oppenheimer, A. Balsam, 1975, New York state journal of medicine.

Effects of essential fatty acid deficiency during late gestation on brain N-acetylneuraminic acid metabolism and behaviour in the progeny

B. Morgan, M. Winick, J. Oppenheimer, 1981, British Journal of Nutrition.

CLINICAL ENDOCRINOLOGY & METABOLISM

S. Grundy, M. Fillyaw, J. Norton, 1992 .

Revised nomenclature for tests of thyroid hormones and thyroid-related proteins in serum.

P. Larsen, C. Mariash, J. Hershman, 1987, Archives of pathology & laboratory medicine.

Alpha-amanitin administration results in a temporary inhibition of hepatic enzyme induction by triiodothyronine: further evidence favoring a long-lived mediator of thyroid hormone action.

M. Surks, J. Oppenheimer, W. Dillmann, 1977, Endocrinology.

Immunofluorescence localization of thyroid hormone receptor protein /31 and variant a2 in selected tissues: Cerebellar Purkinje cells as a model for /81 receptor-mediated developmental effects of thyroid hormone in brain

N. Ling, K. Strait, J. Oppenheimer, 2022 .

Regulation of gene S-14 by triiodothyronine in liver.

N. Wong, C. Mariash, W. Kinlaw, 1987, Hormone and metabolic research. Supplement series.

Thyroid function tests in nonthyroidal disease.

J. Oppenheimer, 1982, Journal of chronic diseases.

Stereospecific transport of triidothyronine to cytoplasm and nucleus in GH1 cells

H. Freake, A. Mooradian, J. Oppenheimer, 1986, Molecular and Cellular Endocrinology.

Thyroid hormone-carbohydrate interaction at the hepatic nuclear level.

C. Mariash, J. Oppenheimer, 1982, Federation proceedings.

Growth hormone acts at a pretranslational level in hepatocyte cultures.

C. Mariash, D. Topliss, J. Oppenheimer, 1983, Biochemical and biophysical research communications.

Ontogeny of Hepatic Nuclear Triiodothyronine Isoforms in the Rat

K. Strait, J. Oppenheimer, C. Rodd, 1992 .

Turnover of 131-I-thyroxine in patients subjected to surgical trauma.

J. Oppenheimer, G. Bernstein, J. Hasen, 1967, The Journal of clinical endocrinology and metabolism.