T. Nakagawa

发表

Reduced PHOX2B stability causes axonal growth impairment in motor neurons with TARDBP mutations

H. Okano, T. Fujii, K. Nakayama, 2021, Stem cell reports.

Anchoring of the 26S proteasome to the organellar membrane by FKBP38

Tohru Natsume, Keiichi I Nakayama, K. Nakayama, 2007, Genes to cells : devoted to molecular & cellular mechanisms.

VprBP (DCAF1): a promiscuous substrate recognition subunit that incorporates into both RING-family CRL4 and HECT-family EDD/UBR5 E3 ubiquitin ligases

P. Swanson, T. Nakagawa, K. Mondal, 2013, BMC Molecular Biology.

USP15 suppresses tumor immunity via deubiquitylation and inactivation of TET2

Matthew D. Smith, Y. Xiong, N. G. Brown, 2020, Science Advances.

Regulation of mitosis-meiosis transition by the ubiquitin ligase β-TrCP in male germ cells

K. Nakayama, D. Zarkower, T. Nakagawa, 2017, Development.

X-Linked Mental Retardation Gene Product CUL4B Targets Ubiquitylation of H3K4 Methyltransferase Core Component WDR5 and Regulates Neuronal Gene Expression

Y. Xiong, T. Nakagawa, 2011 .

Regulation of procaspase-2 by glucocorticoid modulatory element-binding protein 1 through the interaction with caspase recruitment domain.

T. Uehara, Y. Nomura, K. Tsuruma, 2004, Biochemical and biophysical research communications.

Vpr Targets TET2 for Degradation by CRL4VprBP E3 Ligase to Sustain IL-6 Expression and Enhance HIV-1 Replication.

Y. Xiong, L. Su, Haitao Guo, 2018, Molecular cell.

Pathogenic mutations in the ALS gene CCNF cause cytoplasmic mislocalization of Cyclin F and elevated VCP ATPase activity.

K. Nakayama, N. Ishida, N. Suzuki, 2019, Human molecular genetics.

GMEB1, a novel endogenous caspase inhibitor, prevents hypoxia- and oxidative stress-induced neuronal apoptosis

T. Uehara, Y. Nomura, K. Tsuruma, 2008, Neuroscience Letters.

Glucocorticoid Modulatory Element-binding Protein 1 Binds to Initiator Procaspases and Inhibits Ischemia-induced Apoptosis and Neuronal Injury*

H. Hara, T. Uehara, Y. Nomura, 2006, Journal of Biological Chemistry.

Neurobehavioral characteristics of mice with SETD5 mutations as models of IDD23 and KBG syndromes

K. Nakayama, T. Hosoi, T. Nakagawa, 2023, Frontiers in Genetics.

T. Inada, K. Nakayama, K. Nakayama, 2020, iScience.

CHD8 suppresses p53-mediated apoptosis through histone H1 recruitment during early embryogenesis

K. Nakayama, Masaaki Nishiyama, T. Natsume, 2009, Nature Cell Biology.

X-linked mental retardation gene CUL4B targets ubiquitylation of H3K4 methyltransferase component WDR5 and regulates neuronal gene expression.

Y. Xiong, T. Nakagawa, 2011, Molecular cell.

CRL4(VprBP) E3 ligase promotes monoubiquitylation and chromatin binding of TET dioxygenases.

Xian Chen, Yue Xiong, Xian Chen, 2015, Molecular cell.

SPT16 ubiquitylation by DCAF14-CRL4 regulates FACT binding to histones.

K. Nakayama, A. Morohoshi, T. Hosoi, 2022, Cell reports.

Knockout Mouse Models Provide Insight into the Biological Functions of CRL1 Components.

K. Nakayama, K. Nakayama, T. Nakagawa, 2020, Advances in experimental medicine and biology.

Variants in CUL4B are Associated with Cerebral Malformations

A. V. Vulto-van Silfhout, L. Vissers, S. Haas, 2015, Human mutation.

An Amyotrophic Lateral Sclerosis-Associated Mutant of C21ORF2 Is Stabilized by NEK1-Mediated Hyperphosphorylation and the Inability to Bind FBXO3

K. Nakayama, N. Suzuki, Yasuaki Watanabe, 2020, iScience.

The SCFβ-TRCP E3 ubiquitin ligase complex targets Lipin1 for ubiquitination and degradation to promote hepatic lipogenesis

A. Toker, Jinfang Zhang, Wenyi Wei, 2017, Science Signaling.

Aberrant axon branching via Fos-B dysregulation in FUS-ALS motor neurons

H. Okano, T. Fujii, K. Nakayama, 2019, EBioMedicine.

Protein monoubiquitylation: targets and diverse functions

K. Nakayama, T. Nakagawa, 2015, Genes to cells : devoted to molecular & cellular mechanisms.

Transforming Growth Factor β-Induced Proliferative Arrest Mediated by TRIM26-Dependent TAF7 Degradation and Its Antagonism by MYC

K. Nakayama, R. Funayama, A. Morohoshi, 2017, Molecular and Cellular Biology.

Ubiquitylation of Ku80 by RNF126 Promotes Completion of Nonhomologous End Joining-Mediated DNA Repair

Yasutake Katoh, Noriko Ishida, A. Yasui, 2016, Molecular and Cellular Biology.

Fbxw7 contributes to tumor suppression by targeting multiple proteins for ubiquitin‐dependent degradation

Akinobu Matsumoto, E. Susaki, K. Nakayama, 2006, Cancer science.

S6 Kinase- and β-TrCP2-Dependent Degradation of p19Arf Is Required for Cell Proliferation

K. Nakayama, M. Unno, A. Hirao, 2015, Molecular and Cellular Biology.

Insulin Enhances Gene Expression of Midnolin, a Novel Genetic Risk Factor for Parkinson’s Disease, via Extracellular Signal-Regulated Kinase, Phosphoinositide 3-Kinase and Multiple Transcription Factors in SH-SY5Y Cells

Y. Obara, K. Ishii, T. Hosoi, 2022, The Journal of Pharmacology and Experimental Therapeutics.

Long non-coding RNA ANRIL is required for the PRC2 recruitment to and silencing of p15INK4B tumor suppressor gene

M. Kitagawa, Y. Kotake, K. Kitagawa, 2011, Oncogene.

CRL4(VprBP) E3 ligase promotes monoubiquitylation and chromatin binding of TET dioxygenases.

Xian Chen, Yanbao Yu, K. Nakayama, 2015, Molecular cell.

X-linked mental retardation gene CUL4B targets ubiquitylation of H3K4 methyltransferase component WDR5 and regulates neuronal gene expression.

Y. Xiong, T. Nakagawa, 2011, Molecular cell.