M. Mompeán

发表

An Amyloid-Like Pathological Conformation of TDP-43 Is Stabilized by Hypercooperative Hydrogen Bonds

D. Laurents, E. Buratti, M. Baralle, 2016, Front. Mol. Neurosci..

Glycine Rich Segments Adopt Polyproline II Helices Which May Contribute to Biomolecular Condensate Formation

D. Laurents, A. Doig, D. Pantoja-Uceda, 2020, bioRxiv.

Unraveling the toxic effects mediated by the neurodegenerative disease–associated S375G mutation of TDP-43 and its S375E phosphomimetic variant

D. Laurents, E. Buratti, M. Romano, 2022, The Journal of biological chemistry.

SUMOylation Regulates TDP-43 Splicing Activity and Nucleocytoplasmic Distribution

E. Buratti, A. Ratti, V. Silani, 2021, Molecular Neurobiology.

DMSO affects Aβ1–40's conformation and interactions with aggregation inhibitors as revealed by NMR

D. Laurents, J. Carrodeguas, D. Pantoja-Uceda, 2015 .

Partial structure, dampened mobility, and modest impact of a His tag in the SARS-CoV-2 Nsp2 C-terminal region

D. Laurents, M. Mompeán, M. Treviño, 2021, European Biophysics Journal.

Do polyproline II helix associations modulate biomolecular condensates?

D. Laurents, M. Mompeán, J. Oroz, 2021, FEBS open bio.

Pushing nuclear magnetic resonance sensitivity limits with microfluidics and photo-chemically induced dynamic nuclear polarization

Vittorio Saggiomo, A. de la Hoz, V. Saggiomo, 2018, Nature Communications.

The Structure of the Necrosome RIPK1-RIPK3 Core, a Human Hetero-Amyloid Signaling Complex

Hao Wu, A. McDermott, Jixi Li, 2018, Cell.

Structural insight into the XTACC3/XMAP215 interaction from CD and NMR studies on model peptides

M. Jiménez, M. Bruix, M. Mompeán, 2017, Biopolymers.

Comprehensive Fragment Screening of the SARS‐CoV‐2 Proteome Explores Novel Chemical Space for Drug Development

D. Laurents, J. Hoch, K. Saxena, 2022, Angewandte Chemie.

The Singular NMR Fingerprint of a Polyproline II Helical Bundle.

D. Laurents, D. Pantoja-Uceda, M. Menéndez, 2018, Journal of the American Chemical Society.

The TDP‐43 N‐terminal domain structure at high resolution

D. Laurents, D. Pantoja-Uceda, E. Buratti, 2016, The FEBS journal.

Complex System Assembly Underlies a Two-Tiered Model of Highly Delocalized Electrons.

D. Laurents, A. Nogales, T. Ezquerra, 2016, The journal of physical chemistry letters.

Phe-Gly motifs drive fibrillization of TDP-43’s prion-like domain condensates

D. Laurents, A. McDermott, D. Pantoja-Uceda, 2021, PLoS biology.

Dysregulation of TDP‐43 intracellular localization and early onset ALS are associated with a TARDBP S375G variant

Gary L. Pattee, D. Laurents, B. Ghetti, 2019, Brain pathology.

Structural Evidence of Amyloid Fibril Formation in the Putative Aggregation Domain of TDP-43.

D. Laurents, T. Tran, L. Tong, 2015, The journal of physical chemistry letters.

Large-Scale Recombinant Production of the SARS-CoV-2 Proteome for High-Throughput and Structural Biology Applications

Rachel W. Martin, D. Laurents, J. Hoch, 2021, Frontiers in Molecular Biosciences.

Molecular mechanism of the inhibition of TDP-43 amyloidogenesis by QBP1.

D. Laurents, M. Carrión-Vázquez, R. Hervás, 2019, Archives of biochemistry and biophysics.

“Deciphering the amyloid foldome of TDP-43”

D. Laurents, E. Buratti, M. Mompeán, 2019, bioRxiv.

Mimicry by a viral RHIM

Hao Wu, M. Mompeán, Gunes Bozkurt, 2019, EMBO reports.

"Structural characterization of the minimal segment of TDP-43 competent for aggregation".

D. Laurents, E. Buratti, F. Baralle, 2014, Archives of biochemistry and biophysics.

Insight into Polyproline II Helical Bundle Stability and Folding from NMR Spectroscopic Characterization of the Snow Flea Antifreeze Protein Denatured State

D. Laurents, D. Pantoja-Uceda, M. Mompeán, 2022, bioRxiv.

Phe-Gly motifs drive fibrillization of TDP-43’s prion-like domain droplets

D. Laurents, A. McDermott, D. Pantoja-Uceda, 2020, bioRxiv.

Point mutations in the N-terminal domain of transactive response DNA-binding protein 43 kDa (TDP-43) compromise its stability, dimerization, and functions

D. Laurents, D. Pantoja-Uceda, E. Buratti, 2017, The Journal of Biological Chemistry.

Point mutations in transactive response DNA-binding protein 43 ( TDP-43 ) ’ s N-terminal domain compromise its stability , dimerization and functions

D. Laurents, D. Pantoja-Uceda, E. Buratti, 2017 .

Electrostatic Repulsion Governs TDP-43 C-terminal Domain Aggregation

D. Laurents, E. Buratti, A. Chakrabartty, 2016, PLoS biology.

Aromatic and aliphatic residues of the disordered region of TDP-43 are on a fast track for self-assembly.

D. Laurents, D. Pantoja-Uceda, E. Buratti, 2021, Biochemical and biophysical research communications.

NMR assignments for the C-terminal domain of human TDP-43

D. Laurents, A. McDermott, D. Pantoja-Uceda, 2021, Biomolecular NMR Assignments.

Pushing nuclear magnetic resonance sensitivity limits with microfluidics and photo-chemically induced dynamic nuclear polarization

A. de la Hoz, V. Saggiomo, A. Velders, 2018, Nature Communications.

SARS-CoV-2 Nsp8 N-terminal domain dimerizes and harbors autonomously folded elements

D. Laurents, D. Pantoja-Uceda, M. Mompeán, 2021, bioRxiv.

Insights into protein-carbohydrate recognition: A novel binding mechanism for CBM family 43.

M. Bruix, M. Villalba, M. Mompeán, 2017, Journal of molecular graphics & modelling.

NMR assignments for the C-terminal domain of human TDP-43

D. Laurents, A. McDermott, D. Pantoja-Uceda, 2021, Biomolecular NMR Assignments.

Combining Classical MD and QM calculations to elucidate complex system nucleation: a twisted, three-stranded, parallel β-sheet seeds amyloid fibril conception.

D. Laurents, E. Lomba, M. Mompeán, 2014, The journal of physical chemistry. B.

Glycine rich segments adopt polyproline II helices: Implications for biomolecular condensate formation.

D. Laurents, A. Doig, D. Pantoja-Uceda, 2021, Archives of biochemistry and biophysics.

The Structure of the Necrosome RIPK 1-RIPK 3 Core , a Human Hetero-Amyloid Signaling Complex Graphical Abstract Highlights

A. McDermott, Jixi Li, Ansgar B. Siemer, 2018 .

Insights into protein-carbohydrate recognition: A novel binding mechanism for CBM family 43.

M. Bruix, M. Villalba, M. Mompeán, 2017, Journal of molecular graphics & modelling.