S. Uryu

发表

Selective incorporation of 5-hydroxytryptophan into proteins in mammalian cells

P. Schultz, D. King, Feng Tian, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Distinct FAK-Src activation events promote α5β1 and α4β1 integrin-stimulated neuroblastoma cell motility

S. Lim, D. Schlaepfer, D. Mikolon, 2008, Oncogene.

Translational Pharmacokinetic-Pharmacodynamic Modeling for an Orally Available Novel Inhibitor of Epigenetic Regulator Enhancer of Zeste Homolog 2

S. Yamazaki, Shikhar Sharma, Hui Wang, 2020, The Journal of Pharmacology and Experimental Therapeutics.

Inhibition of endothelial FAK activity prevents tumor metastasis by enhancing barrier function

E. Dejana, Xiao Lei Chen, D. Schlaepfer, 2014, The Journal of cell biology.

Nuclear-localized focal adhesion kinase regulates inflammatory VCAM-1 expression

S. Lim, Xiao Lei Chen, D. Schlaepfer, 2012, The Journal of cell biology.

FAK promotes recruitment of talin to nascent adhesions to control cell motility

S. Lim, Xiao Lei Chen, D. Schlaepfer, 2012, The Journal of Cell Biology.

FAK promotes recruitment of talin to nascent adhesions to control cell motility

S. Lim, Xiao Lei Chen, D. Schlaepfer, 2012, The Journal of cell biology.

Src-inducible association of CrkL with procaspase-8 promotes cell migration

D. Schlaepfer, D. Stupack, R. Graf, 2013, Cell adhesion & migration.

Oral delivery of PND-1186 FAK inhibitor decreases tumor growth and spontaneous breast to lung metastasis in pre-clinical models

G. Mcmahon, D. Schlaepfer, D. Stupack, 2010, Cancer biology & therapy.

Site-specific incorporation of a redox-active amino acid into proteins.

P. Schultz, J. Loo, L. Alfonta, 2003, Journal of the American Chemical Society.

PyK2 and FAK connections to p190Rho guanine nucleotide exchange factor regulate RhoA activity, focal adhesion formation, and cell motility

M. Gardel, G. Bokoch, C. Waterman-Storer, 2008, The Journal of cell biology.

PyK 2 and FAK connections to p 190 Rho guanine nucleotide exchange factor regulate RhoA activity , focal adhesion formation , and cell motility

M. Gardel, G. Bokoch, C. Waterman-Storer, 2008 .

Optimization of Orally Bioavailable Enhancer of Zeste Homolog 2 (EZH2) Inhibitors Using Ligand and Property-Based Design Strategies: Identification of Development Candidate (R)-5,8-Dichloro-7-(methoxy(oxetan-3-yl)methyl)-2-((4-methoxy-6-methyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-3,4-dihydroisoquin

K. Gajiwala, N. Sach, P. Kung, 2017, Journal of medicinal chemistry.

FAK activity protects nucleostemin in facilitating breast cancer spheroid and tumor growth

D. Schlaepfer, C. Jean, N. Miller, 2015, Breast Cancer Research.

PND-1186 FAK inhibitor selectively promotes tumor cell apoptosis in three-dimensional environments

G. Mcmahon, S. Lim, D. Schlaepfer, 2010, Cancer biology & therapy.

A non-canonical role for Rgnef in promoting integrin-stimulated focal adhesion kinase activation

D. Schlaepfer, N. Miller, S. Uryu, 2013, Journal of Cell Science.

FAK Inhibition Disrupts a β5 Integrin Signaling Axis Controlling Anchorage-Independent Ovarian Carcinoma Growth

D. Schlaepfer, C. Jean, N. Miller, 2014, Molecular Cancer Therapeutics.

Cancer Biology and Signal Transduction FAK Inhibition Disrupts a b 5 Integrin Signaling Axis Controlling Anchorage-Independent Ovarian Carcinoma Growth

D. Schlaepfer, C. Jean, N. Miller, 2014 .

VEGF-induced vascular permeability is mediated by FAK.

J. Guan, S. Lim, D. Schlaepfer, 2012, Developmental cell.

Analyses of merlin/NF2 connection to FAK inhibitor responsiveness in serous ovarian cancer.

D. Schlaepfer, C. Jean, N. Miller, 2014, Gynecologic oncology.

Title Analyses of merlin / NF 2 connection to FAK inhibitor responsiveness in serous ovarian cancer

D. Schlaepfer, C. Jean, N. Miller, 2014 .

Tumor Necrosis Factor-α Stimulates Focal Adhesion Kinase Activity Required for Mitogen-activated Kinase-associated Interleukin 6 Expression*

S. Lim, Y. Lim, D. A. Hanson, 2007, Journal of Biological Chemistry.

kinase regulates expression.

S. Lim, D. Schlaepfer, D. Cheresh, 2012 .

Inhibition of focal adhesion kinase (FAK) activity prevents anchorage-independent ovarian carcinoma cell growth and tumor progression

D. Tarin, D. Schlaepfer, C. Jean, 2013, Clinical & Experimental Metastasis.

FAK activity sustains intrinsic and acquired ovarian cancer resistance to platinum chemotherapy

B. Győrffy, J. Heino, D. Schlaepfer, 2019, bioRxiv.

Distinct FAK-Src activation events promote alpha5beta1 and alpha4beta1 integrin-stimulated neuroblastoma cell motility.

D. Schlaepfer, D. Mikolon, D. Stupack, 2008, Oncogene.

Discovery of a highly potent, selective, orally bioavailable inhibitor of KAT6A/B histone acetyltransferases with efficacy against KAT6A-high ER+ breast cancer.

Chin Wee Tan, Dharmesh D. Bhuva, Eric C Greenwald, 2023, Cell chemical biology.

A New Strategy for the Synthesis of Glycoproteins

Peter G. Schultz, Joseph A. Loo, Chi-Huey Wong, 2004, Science.

PyK2 and FAK connections to p190Rho guanine nucleotide exchange factor regulate RhoA activity, focal adhesion formation, and cell motility

M. Gardel, G. Bokoch, C. Waterman-Storer, 2008, The Journal of cell biology.