M. Eigenthaler

发表

A Stimulatory Role for cGMP-Dependent Protein Kinase in Platelet Activation

F. Hofmann, R. Feil, Xiaoping Du, 2003, Cell.

Activated platelets induce migration, proliferation and gene expression in human vascular endothelial cells

M. Eigenthaler, U. R. Schwarz, B. Schinke, 2003 .

Wild‐type isolates of Porphyromonas gingivalis derived from periodontitis patients display major variability in platelet activation

S. Störk, A. Stellzig-Eisenhauer, U. Schlagenhauf, 2018, Journal of clinical periodontology.

ADP-induced platelet aggregation frequently fails to detect impaired clopidogrel-responsiveness in patients with coronary artery disease compared to a P2Y12-specific assay

U. Walter, G. Ertl, S. Störk, 2008, Thrombosis and Haemostasis.

PRL as a novel potent cofactor for platelet aggregation.

H. Wallaschofski, H. Stepan, T. Lohmann, 2001, The Journal of clinical endocrinology and metabolism.

Novel role of the membrane-bound chemokine fractalkine in platelet activation and adhesion.

U. Walter, M. Gawaz, G. Ertl, 2004, Blood.

Interaction of Neisseria meningitidis with human brain microvascular endothelial cells: role of MAP‐ and tyrosine kinases in invasion and inflammatory cytokine release

O. Sokolova, K. Kim, M. Frosch, 2004, Cellular microbiology.

Increased platelet activation in young Zucker rats with impaired glucose tolerance is improved by acarbose

G. Ertl, J. Bauersachs, A. Schäfer, 2004, Thrombosis and Haemostasis.

Reduced basal nitric oxide bioavailability and platelet activation in young spontaneously hypertensive rats.

G. Ertl, J. Bauersachs, A. Schäfer, 2004, Biochemical pharmacology.

Protein phosphorylation regulated by cyclic nucleotide-dependent protein kinases in cell extracts and in intact human lymphocytes.

U. Walter, M. Eigenthaler, M. Halbrügge, 1992, Cellular signalling.

Rosuvastatin Reduces Platelet Activation in Heart Failure: Role of NO Bioavailability

G. Ertl, J. Bauersachs, A. Schäfer, 2005, Arteriosclerosis, thrombosis, and vascular biology.

Inhibition of platelet activation in congestive heart failure by aldosterone receptor antagonism and ACE inhibition

U. Walter, J. Bauersachs, A. Schäfer, 2003, Thrombosis and Haemostasis.

Inhibition of platelet activation in rats with severe congestive heart failure by a novel endothelial nitric oxide synthase transcription enhancer

G. Ertl, J. Bauersachs, A. Schäfer, 2009, European journal of heart failure.

Fibronectin mediates Opc‐dependent internalization of Neisseria meningitidis in human brain microvascular endothelial cells

K. Kim, M. Frosch, G. Dietrich, 2002, Molecular microbiology.

A predominant role for cAMP-dependent protein kinase in the cGMP-induced phosphorylation of vasodilator-stimulated phosphoprotein and platelet inhibition in humans.

Xiaoping Du, Zhenyu Li, M. Eigenthaler, 2003, Blood.

Enhanced in vivo platelet adhesion in vasodilator-stimulated phosphoprotein (VASP)-deficient mice.

U. Heinzmann, U. Walter, M. Gawaz, 2004, Blood.

Defective nitrovasodilator-stimulated protein phosphorylation and calcium regulation in cGMP-dependent protein kinase-deficient human platelets of chronic myelocytic leukemia.

U. Walter, J. Geiger, H. Ullrich, 1993, The Journal of biological chemistry.

Hearing development and spiral ganglion neurite growth in VASP deficient mice

U. Walter, A. Ryan, S. Dazert, 2007, Brain Research.

Increased noise sensitivity and altered inner ear MENA distribution in VASP−/− mice

M. Knipper, Marcus Müller, U. Walter, 2004, Cell and Tissue Research.

Affinity Modulation of Platelet Integrin αIIbβ3 by β3-Endonexin, a Selective Binding Partner of the β3 Integrin Cytoplasmic Tail

M. Schwartz, M. Ginsberg, S. Shattil, 1997, The Journal of cell biology.

The CX3C Chemokine Fractalkine Induces Vascular Dysfunction by Generation of Superoxide Anions

G. Ertl, J. Bauersachs, A. Schäfer, 2007, Arteriosclerosis, thrombosis, and vascular biology.

Signal transduction by cGMP-dependent protein kinases and their emerging roles in the regulation of cell adhesion and gene expression.

U. Walter, S. Lohmann, R. Pilz, 1999, Reviews of physiology, biochemistry and pharmacology.

Gene Expression Pattern in Human Brain Endothelial Cells in Response to Neisseria meningitidis (cid:1) †

O. Sokolova, M. Frosch, M. Eigenthaler, 2007 .

Flow Cytometry Analysis of Intracellular VASP Phosphorylation for the Assessment of Activating and Inhibitory Signal Transduction Pathways in Human Platelets

U. Walter, J. Geiger, M. Eigenthaler, 1999, Thrombosis and Haemostasis.

Vasodilator-stimulated Phosphoprotein Activation of Serum-response Element-dependent Transcription Occurs Downstream of RhoA and Is Inhibited by cGMP-dependent Protein Kinase Phosphorylation*

U. Walter, T. Jarchau, Yongchang Chen, 2004, Journal of Biological Chemistry.

Inhibition of agonist-induced p42 and p38 mitogen-activated protein kinase phosphorylation and CD40 ligand/P-selectin expression by cyclic nucleotide-regulated pathways in human platelets.

U. Walter, M. Koksch, M. Eigenthaler, 2000, Biochemical pharmacology.

Neisseria meningitidis induces platelet inhibition and increases vascular endothelial permeability via nitric oxide regulated pathways

S. Gambaryan, M. Eigenthaler, A. Schubert-Unkmeir, 2011, Thrombosis and Haemostasis.

PTH1R Mutants Found in Patients with Primary Failure of Tooth Eruption Disrupt G-Protein Signaling

H. Subramanian, E. Wischmeyer, S. Gambaryan, 2016, PloS one.

Phosphatidylserine surface expression and integrin αIIbβ3 activity on thrombin/convulxin stimulated platelets/particles of different sizes

U. Walter, J. Geiger, S. Gambaryan, 2009, British journal of haematology.

Septic Vs Colonizing Group B Streptococci Differentially Regulate Inflammation and Apoptosis in Human Coronary Artery Endothelial Cells - a Pilot Study

J. Löffler, C. Löffler, M. Eigenthaler, 2015 .

Variable extent of clopidogrel responsiveness in patients after coronary stenting

O. Sokolova, B. Lengenfelder, M. Eigenthaler, 2004, Thrombosis and Haemostasis.

Synergistic phosphorylation of the focal adhesion-associated vasodilator-stimulated phosphoprotein in intact human platelets in response to cGMP- and cAMP-elevating platelet inhibitors.

U. Walter, M. Eigenthaler, C. Nolte, 1994, Biochemical pharmacology.

activation and adhesion Novel role of the membrane-bound chemokine fractalkine in platelet

U. Walter, G. Ertl, J. Bauersachs, 2010 .

Cyclic nucleotide-regulated proliferation and differentiation vary in human hematopoietic progenitor cells derived from healthy persons, tumor patients, and chronic myelocytic leukemia patients.

U. Walter, S. Gambaryan, M. Eigenthaler, 2008, Stem cells and development.

Expanding the spectrum of PTH1R mutations in patients with primary failure of tooth eruption

L. Fritsche, P. Proff, A. Stellzig-Eisenhauer, 2013, Clinical Oral Investigations.

Stimulation of the nitrate-nitrite-NO-metabolism by repeated lettuce juice consumption decreases gingival inflammation in periodontal recall patients: a randomized, double-blinded, placebo-controlled clinical trial.

R. Carle, U. Schlagenhauf, R. Schweiggert, 2016, Journal of clinical periodontology.

Correlation between Mononuclear Infiltration and Changes in VASP Phosphorylation Patterns after Heterotopic Cardiac Transplantation in the Rat

B. Reichart, U. Walter, T. Deuse, 2003, European Surgical Research.

Enhanced platelet activation by prolactin in patients with ischemic stroke

W. Daniel, H. Wallaschofski, E. Hahn, 2004 .

Co-activation of platelets by prolactin or leptin--pathophysiological findings and clinical implications.

H. Wallaschofski, O. Sokolova, T. Lohmann, 2004, Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme.

Prolactin receptor signaling during platelet activation.

H. Wallaschofski, O. Sokolova, T. Lohmann, 2003, Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme.

Differences in platelet activation by prolactin and leptin.

H. Wallaschofski, O. Sokolova, H. Stepan, 2004, Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme.

Endothelial cell-dependent phosphorylation of a platelet protein mediated by cAMP- and cGMP-elevating factors.

U. Walter, M. Eigenthaler, C. Nolte, 1991, The Journal of biological chemistry.

Distribution and Activation of cAMP- and cGMP-Dependent Protein Kinases in Highly Purified Human Platelet Plasma and Intracellular Membranes

K. Mikoshiba, A. Miyawaki, U. Walter, 1996, Thrombosis and Haemostasis.

Role of cyclic nucleotide-dependent protein kinases and their common substrate VASP in the regulation of human platelets.

U. Walter, J. Geiger, M. Reinhard, 1993, Advances in experimental medicine and biology.

Functional analysis of cGMP-dependent protein kinases I and II as mediators of NO/cGMP effects

U. Walter, S. Lohmann, S. Gambaryan, 1998, Naunyn-Schmiedeberg's Archives of Pharmacology.

Comparison of vasodilatory prostaglandins with respect to cAMP-mediated phosphorylation of a target substrate in intact human platelets.

U. Walter, M. Eigenthaler, C. Nolte, 1991, Biochemical pharmacology.

Differential diagnosis of primary failure of eruption (PFE) with and without evidence of pathogenic mutations in the PTHR1 gene

A. Stellzig-Eisenhauer, P. Meyer-Marcotty, M. Eigenthaler, 2014, Journal of Orofacial Orthopedics / Fortschritte der Kieferorthopädie.

Specific impairment of human platelet P2Y(AC) ADP receptor-mediated signaling by the antiplatelet drug clopidogrel.

U. Walter, J. Geiger, J. Herbert, 1999, Arteriosclerosis, thrombosis, and vascular biology.

Concentration and regulation of cyclic nucleotides, cyclic-nucleotide-dependent protein kinases and one of their major substrates in human platelets. Estimating the rate of cAMP-regulated and cGMP-regulated protein phosphorylation in intact cells.

U. Walter, M. Eigenthaler, M. Halbrügge, 1992, European journal of biochemistry.

Qualitative and quantitative changes in the oral bacterial flora occur shortly after implementation of fixed orthodontic appliances.

W. Pfister, J. Rödel, B. Löffler, 2019, American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics.

Regular consumption of Lactobacillus reuteri‐containing lozenges reduces pregnancy gingivitis: an RCT

U. Schlagenhauf, Lena Jakob, Y. Jockel-Schneider, 2016, Journal of clinical periodontology.

Platelet Flow Cytometry – A New Dimension/Durchflußzytometrische Thrombozytendiagnostik – Eine Neue Dimension

M. Eigenthaler, U. R. Schwarz, U. Schwarz, 2002 .

Beta 3-endonexin, a novel polypeptide that interacts specifically with the cytoplasmic tail of the integrin beta 3 subunit

M. Ginsberg, B. Babior, T. O’Toole, 1995, The Journal of cell biology.

Megakaryocyte hyperplasia and enhanced agonist-induced platelet activation in vasodilator-stimulated phosphoprotein knockout mice.

K. Knobeloch, U. Walter, J. Geiger, 1999, Proceedings of the National Academy of Sciences of the United States of America.

Enhanced platelet activation by prolactin in patients with ischemic stroke

W. Daniel, H. Wallaschofski, C. Stumpf, 2004, Thrombosis and Haemostasis.

Hyperprolactinemia in Patients on Antipsychotic Drugs Causes ADP-Stimulated Platelet Activation That Might Explain the Increased Risk for Venous Thromboembolism: Pilot Study

H. Gertz, H. Wallaschofski, T. Lohmann, 2003, Journal of clinical psychopharmacology.

Infection of Human Coronary Artery Endothelial Cells by Group B Streptococcus Contributes to Dysregulation of Apoptosis, Hemostasis, and Innate Immune Responses

S. Kneitz, J. Löffler, M. Eigenthaler, 2011, Mediators of inflammation.

Impact of anti‐infective periodontal therapy on parameters of vascular health

S. Störk, I. Harks, U. Schlagenhauf, 2018, Journal of clinical periodontology.

Taming platelets with cyclic nucleotides.

U. Walter, M. Eigenthaler, U. Schwarz, 2001, Biochemical pharmacology.

Affinity Modulation of Platelet Integrin (cid:97) IIb by 3 -Endonexin, a Selective Binding Partner of the (cid:98) 3 Integrin Cytoplasmic Tail

M. Schwartz, M. Ginsberg, S. Shattil, 1997 .

Chapter 13 Integrin Signaling and the Platelet Cytoskeleton

S. Shattil, M. Eigenthaler, 1996 .

CORONARY ARTERY DISEASE Original Studies Resistance to Thienopyridines: Clinical Detection of Coronary Stent Thrombosis by Monitoring of Vasodilator-Stimulated Phosphoprotein Phosphorylation

U. Walter, P. Barragan, P. Commeau, 2003 .

Platelet Flow Cytometry – A New Dimension

M. Eigenthaler, U. Schwarz, 2002 .

Rapid Regulation of Platelet Activation In Vivo by Nitric Oxide

S. Neubauer, K. Channon, J. Bauersachs, 2003, Circulation.

A Conserved Sequence Motif in the Integrin β3 Cytoplasmic Domain Is Required for Its Specific Interaction with β3-Endonexin*

M. Ginsberg, S. Shattil, L. Höfferer, 1997, The Journal of Biological Chemistry.

Vasodilator-Stimulated Phosphoprotein Regulates Proliferation and Growth Inhibition by Nitric Oxide in Vascular Smooth Muscle Cells

U. Walter, A. Clowes, G. Daum, 2004 .

Arterial Stiffness and Pulse Wave Reflection Are Increased in Patients Suffering from Severe Periodontitis

I. Harks, U. Schlagenhauf, S. Fickl, 2014, PloS one.

Stoichiometric and reversible phosphorylation of a 46-kDa protein in human platelets in response to cGMP- and cAMP-elevating vasodilators.

U. Walter, M. Eigenthaler, M. Halbrügge, 1990, The Journal of biological chemistry.

Gene Expression Pattern in Human Brain Endothelial Cells in Response to Neisseria meningitidis

O. Sokolova, M. Frosch, M. Eigenthaler, 2006, Infection and Immunity.

A conserved sequence motif in the integrin beta3 cytoplasmic domain is required for its specific interaction with beta3-endonexin.

M. Ginsberg, S. Shattil, L. Höfferer, 1997, The Journal of biological chemistry.

Group B streptococcus isolates from septic patients and healthy carriers differentially activate platelet signaling cascades

M. Eigenthaler, M. Abele-Horn, A. Schubert-Unkmeir, 2006, Thrombosis and Haemostasis.

The Cytoskeleton of the Platelet

M. Eigenthaler, A. Kobsar, 2006 .

Severe neutropenia under clopidogrel treatment three weeks after coronary stenting

J. Bauersachs, A. Schäfer, M. Eigenthaler, 2007, Thrombosis and Haemostasis.

Novel Strategies in Anti-Platelet Treatment for Coronary Artery Disease

J. Bauersachs, A. Schäfer, A. Schäfer, 2009 .

Novel Strategies in Anti-Platelet Treatment for Coronary Artery Disease

J. Bauersachs, A. Schäfer, M. Eigenthaler, 2009 .

Late thrombosis of a drug-eluting stent during combined anti-platelet therapy in a clopidogrel nonresponsive diabetic patient: Shall we routinely test platelet function ?

J. Bauersachs, A. Schäfer, M. Eigenthaler, 2007, Thrombosis and Haemostasis.

Improvement of vascular function by acute and chronic treatment with the PDE‐5 inhibitor sildenafil in experimental diabetes mellitus

G. Ertl, J. Bauersachs, A. Schäfer, 2008, British journal of pharmacology.

Soluble Guanylyl Cyclase Activation With HMR1766 Attenuates Platelet Activation in Diabetic Rats

G. Ertl, J. Bauersachs, A. Schäfer, 2006, Arteriosclerosis, thrombosis, and vascular biology.

Reduced Vascular NO Bioavailability in Diabetes Increases Platelet Activation In Vivo

S. Neubauer, N. Alp, K. Channon, 2004, Arteriosclerosis, thrombosis, and vascular biology.

Platelet activation in heart failure.

J. Bauersachs, A. Schäfer, M. Eigenthaler, 2004, Clinical laboratory.

Suppression of endothelial progenitor cells in human coronary artery disease by the endogenous nitric oxide synthase inhibitor asymmetric dimethylarginine.

P. Poole‐Wilson, S. Anker, D. Tsikas, 2005, Journal of the American College of Cardiology.

Tissue inhibitor of metalloproteinases levels in patients with chronic heart failure: An independent predictor of mortality

C. Angermann, G. Ertl, S. Störk, 2008, European journal of heart failure.

Expanding the spectrum of PTH1R mutations in patients with primary failure of tooth eruption

L. Fritsche, P. Proff, A. Stellzig-Eisenhauer, 2013, Clinical Oral Investigations.

Vasodilator-Stimulated Phosphoprotein Regulates Proliferation and Growth Inhibition by Nitric Oxide in Vascular Smooth Muscle Cells

U. Walter, A. Clowes, G. Daum, 2004, Arteriosclerosis, thrombosis, and vascular biology.

Expression of VASP and zyxin in cochlear pillar cells: indication for actin-based dynamics?

M. Knipper, U. Walter, P. Plinkert, 2003, Cell and Tissue Research.

(Rp)-8-pCPT-cGMPS, a novel cGMP-dependent protein kinase inhibitor.

H. Genieser, M. Eigenthaler, E. Butt, 1994, European journal of pharmacology.

Disruption of cardiac Ena-VASP protein localization in intercalated disks causes dilated cardiomyopathy.

M. Lohse, U. Walter, T. Jarchau, 2003, American journal of physiology. Heart and circulatory physiology.

Prolactin receptor signaling during platelet activation.

H. Wallaschofski, O. Sokolova, T. Lohmann, 2003, Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme.

Resistance to thienopyridines: Clinical detection of coronary stent thrombosis by monitoring of vasodilator‐stimulated phosphoprotein phosphorylation

P. Barragan, P. Commeau, A. Lafont, 2003, Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions.

Delayed Formation of Actin Filaments in the Outer Pillar Head Plate of VASP–/– Mice

L. Häberle, M. Knipper, U. Walter, 2007, Cells Tissues Organs.