K. Clark

发表

ANGPTL3 Stimulates Endothelial Cell Adhesion and Migration via Integrin αvβ3 and Induces Blood Vessel Formation in Vivo *

G. Camenisch, P. Hass, A. Gurney, 2002, The Journal of Biological Chemistry.

ANGPTL3 stimulates endothelial cell adhesion and migration via integrin alpha vbeta 3 and induces blood vessel formation in vivo.

G. Camenisch, P. Hass, A. Gurney, 2002, The Journal of biological chemistry.

Activation of the IRE1 RNase through remodeling of the kinase front pocket by ATP-competitive ligands

Peter S Liu, A. Ashkenazi, E. Day, 2020, Nature Communications.

A Unique Approach to Design Potent and Selective Cyclic Adenosine Monophosphate Response Element Binding Protein, Binding Protein (CBP) Inhibitors.

Fei Wang, H. Jayaram, F. A. Romero, 2017, Journal of medicinal chemistry.

Selective α4β7 Integrin Antagonists and Their Potential as Antiinflammatory Agents

D. Sutherlin, N. Skelton, M. Beresini, 2002 .

Competition between intercellular adhesion molecule‐1 and a small‐molecule antagonist for a common binding site on the αl subunit of lymphocyte function‐associated antigen‐1

S. Bodary, T. Gadek, M. Beresini, 2006, Protein science : a publication of the Protein Society.

Structure-activity relationships by mass spectrometry: identification of novel MMP-3 inhibitors.

T. Gadek, J. Stults, M. Struble, 2004, Bioorganic & medicinal chemistry.

Generation of an LFA-1 antagonist by the transfer of the ICAM-1 immunoregulatory epitope to a small molecule.

L. Presta, N. Skelton, S. Bodary, 2002, Science.

Design and Development of a Series of Potent and Selective Type II Inhibitors of CDK8.

K. Bowman, Jiansheng Wu, R. Firestein, 2016, ACS medicinal chemistry letters.

USP7 small-molecule inhibitors interfere with ubiquitin binding

Florian Gnad, Scott E. Martin, Michelle R. Arkin, 2017, Nature.

Structural basis for dual-mode inhibition of the ABC transporter MsbA

Benjamin D. Sellers, Jun Liang, Y. Franke, 2018, Nature.

Structural basis of Nav1.7 inhibition by an isoform-selective small-molecule antagonist

Jun Li, Christine Tam, Daniel F. Ortwine, 2015, Science.

GNE-781, A Highly Advanced Potent and Selective Bromodomain Inhibitor of Cyclic Adenosine Monophosphate Response Element Binding Protein, Binding Protein (CBP).

Karen E Gascoigne, Y. Ran, G. Hatzivassiliou, 2017, Journal of medicinal chemistry.

Development of a Potent, Specific CDK8 Kinase Inhibitor Which Phenocopies CDK8/19 Knockout Cells.

Philippe Bergeron, Kevin R Clark, James R Kiefer, 2016, ACS medicinal chemistry letters.

Small-Molecule Library Subset Screening as an Aid for Accelerating Lead Identification

Kevin R Clark, Timothy D Dawes, Rebecca Turincio, 2014, Journal of biomolecular screening.

Potent α4β1 Peptide Antagonists as Potential Anti-Inflammatory Agents

Dean R. Artis, W. Fairbrother, Susan Jones, 1997 .

Potent alpha 4 beta 1 peptide antagonists as potential anti-inflammatory agents.

K. Chan, W. Fairbrother, D. R. Artis, 1997, Journal of medicinal chemistry.

Compound Transfer by Acoustic Droplet Ejection Promotes Quality and Efficiency in Ultra-High-Throughput Screening Campaigns

Kevin R Clark, Dhireshan Gadiagellan, Timothy D Dawes, 2016, Journal of laboratory automation.

Identification of BRaf-Sparing Amino-Thienopyrimidines with Potent IRE1α Inhibitory Activity.

S. Srivastava, C. Ly, A. Ashkenazi, 2020, ACS medicinal chemistry letters.

Development of a Potent, Specific CDK8 Kinase Inhibitor Which Phenocopies CDK8/19 Knockout Cells.

K. Bowman, Jiansheng Wu, R. Firestein, 2016, ACS medicinal chemistry letters.