P. Reymer

发表

A common variant in the gene for lipoprotein lipase (Asp9→Asn) : functional implications and prevalence in normal and hyperlipidemic subjects

S. Humphries, P. Talmud, A. Hamsten, 1995 .

A common variant in the gene for lipoprotein lipase (Asp9-->Asn). Functional implications and prevalence in normal and hyperlipidemic subjects.

G. Miller, F. Mailly, M. Seed, 1994, Arteriosclerosis, thrombosis, and vascular biology.

Ser447stop mutation in lipoprotein lipase is associated with elevated HDL cholesterol levels in normolipidemic males.

J. Boer, J. Kastelein, J. Seidell, 1997, Arteriosclerosis, thrombosis, and vascular biology.

Lipoprotein lipase activity is decreased in a large cohort of patients with coronary artery disease and is associated with changes in lipids and lipoproteins.

A. Zwinderman, M. Hayden, J. Kastelein, 1999, Journal of lipid research.

Patients with apoE3 deficiency (E2/2, E3/2, and E4/2) who manifest with hyperlipidemia have increased frequency of an Asn 291-->Ser mutation in the human LPL gene.

M. Hayden, J. Kastelein, Ming‐Sun Liu, 1995, Arteriosclerosis, thrombosis, and vascular biology.

A frequently occurring mutation in the lipoprotein lipase gene (Asn291Ser) contributes to the expression of familial combined hyperlipidemia.

D. Kromhout, J. Seidel, P. Reymer, 1995, Human molecular genetics.

The Asn9 variant of lipoprotein lipase is associated with the — 93G promoter mutation and an increased risk of coronary artery disease

E. Boerwinkle, M. Hayden, J. Jukema, 1998, Clinical genetics.

A common mutation in the lipoprotein lipase gene (N291S) alters the lipoprotein phenotype and risk for cardiovascular disease in patients with familial hypercholesterolemia.

M. Hayden, M. Prins, J. Kastelein, 1998, Circulation.

Genetic Variant Showing a Positive Interaction With β-Blocking Agents With a Beneficial Influence on Lipoprotein Lipase Activity, HDL Cholesterol, and Triglyceride Levels in Coronary Artery Disease Patients: The Ser447-Stop Substitution in the Lipoprotein Lipase Gene

E. Boerwinkle, M. Hayden, J. Kastelein, 1997 .

Mutations in the gene for lipoprotein lipase. A cause for low HDL cholesterol levels in individuals heterozygous for familial hypercholesterolemia.

D. Gaudet, M. Hayden, J. Kastelein, 1995, Arteriosclerosis, thrombosis, and vascular biology.

Analysis of the Afrikaner mutation in exon 9 of the low-density lipoprotein receptor gene in a large Dutch kindred suffering from familial hypercholesterolaemia.

J. Kastelein, R. Lamping, P. Lansberg, 1993, The Netherlands journal of medicine.

The Asn9 variant of lipoprotein lipase is associated with the -93G promoter mutation and an increased risk of coronary artery disease. The Regress Study Group.

E. Boerwinkle, M. Hayden, J. Jukema, 1998 .

South African founder mutations in the low-density lipoprotein receptor gene causing familial hypercholesterolemia in the Dutch population

M. Hayden, J. Kastelein, R. Lamping, 1993, Human Genetics.

The lipoprotein lipase (ASN291→SER) mutation is associated with elevated lipid levels in familial combined hyperlipidemia

D. Boomsma, L. Sandkuyl, J. Kastelein, 1995 .

HindIII-polymorphism in the LPL-gene detected by PCR.

J. Kastelein, P. Talmud, P. Reymer, 1991, Nucleic acids research.

Ethnic variation and in vivo effects of the -93t-->g promoter variant in the lipoprotein lipase gene.

M. Hayden, J. Ordovás, J. Kastelein, 1997, Arteriosclerosis, thrombosis, and vascular biology.

The lipoprotein lipase (Asn291-->Ser) mutation is associated with elevated lipid levels in families with familial combined hyperlipidaemia.

P. de Knijff, D. Boomsma, J. Kastelein, 1996, Atherosclerosis.

Compound heterozygosity for a known and a novel defect in the lipoprotein lipase gene (Asp250-->Asn; Ser251-->Cys) resulting in lipoprotein lipase (LPL) deficiency.

M. Hayden, J. Kastelein, G. Assmann, 1996, The Netherlands journal of medicine.

Gender-related association between the -93T-->G/D9N haplotype of the lipoprotein lipase gene and elevated lipid levels in familial combined hyperlipidemia.

H. Snieder, D. Boomsma, J. Kastelein, 1998, Atherosclerosis.

Apolipoprotein E genotyping on agarose gels.

J. Kastelein, P. Reymer, B. E. Groenemeyer, 1995, Clinical chemistry.