J. Gauchat

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Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations

William J. Astle, Andrew D. Johnson, Cassandra N. Spracklen, 2020, Cell.

Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations

William J. Astle, Andrew D. Johnson, P. Elliott, 2020, Cell.

This information is current as PropertiesHydroxyapatite and Bone-Binding A Polyglutamic Acid Motif Confers IL-27

G. Elson, J. Gauchat, A. Tormo, 2013 .

A Polyglutamic Acid Motif Confers IL-27 Hydroxyapatite and Bone-Binding Properties

G. Elson, J. Gauchat, A. Tormo, 2013, The Journal of Immunology.

Type I interferon restricts type 2 immunopathology through the regulation of group 2 innate lymphoid cells

Irah L. King, D. Malo, M. M. Eva, 2015, Nature Immunology.

Human CD40‐ligand: molecular cloning, cellular distribution and regulation of expression by factors controlling IgE production

J. Bonnefoy, G. Mazzei, G. Elson, 1993, FEBS letters.

Unavailability of CD147 leads to selective erythrocyte trapping in the spleen.

H. Macdonald, J. Bonnefoy, T. Renno, 2001, Blood.

Thiols decrease human interleukin (IL) 4 production and IL-4-induced immunoglobulin synthesis

J. Bonnefoy, Y. Delneste, P. Jeannin, 1995, The Journal of experimental medicine.

Comparison of Lipopolysaccharide-Binding Functions of CD14 and MD-2

K. Fukudome, N. Tsuneyoshi, M. Kimoto, 2005, Clinical Diagnostic Laboratory Immunology.

The outer membrane protein X from Escherichia coli exhibits immune properties.

T. Nguyen, Y. Delneste, P. Jeannin, 2003, Vaccine.

Continued administration of ciliary neurotrophic factor protects mice from inflammatory pathology in experimental autoimmune encephalomyelitis.

T. Kuhlmann, J. Antel, T. Owens, 2006, The American journal of pathology.

Identification of three alternatively spliced variants of human CD28 mRNA.

T. Nguyen, J. Bonnefoy, G. Magistrelli, 1999, Biochemical and biophysical research communications.

A new role for CD23 in inflammation.

J. Bonnefoy, J. Gauchat, P. Graber, 1996, Immunology today.

Pseudomonas Protects Neonate Mice from in Breast Milk, Spreads in Tissues, and Prototypic Long Pentraxin PTX3 Is Present

C. Garlanda, A. Mantovani, G. Mancuso, 2013 .

Preparation and characterization of truncated human lipopolysaccharide-binding protein in Escherichia coli.

K. Fukudome, N. Tsuneyoshi, M. Kimoto, 2006, Protein expression and purification.

Cardiotrophin-like Cytokine Increases Macrophage–Foam Cell Transition

G. Mayer, Mukut Sharma, C. Martel, 2018, The Journal of Immunology.

CD23 regulates monocyte activation through a novel interaction with the adhesion molecules CD11b-CD18 and CD11c-CD18.

Á. Corbí, J. Bonnefoy, B. Dugas, 1995, Immunity.

Interleukin‐12 increases interleukin‐4 production by established human ThO and Th2‐like T cell clones

J. Bonnefoy, Y. Delneste, P. Jeannin, 1995, European journal of immunology.

IgE versus IgG4 production can be differentially regulated by IL-10.

J. Bonnefoy, Y. Delneste, P. Jeannin, 1998, Journal of immunology.

IL-10 and viral IL-10 prevent IL-4-induced IgE synthesis by inhibiting the accessory cell function of monocytes.

R. de Waal Malefyt, J. D. de Vries, P. van Vlasselaer, 1993, Journal of immunology.

A novel 4‐kb interleukin‐13 receptor α mRNA expressed in human B, T, and endothelial cells encoding an alternate type‐II interleukin‐4/ interleukin‐13 receptor

L. Notarangelo, J. Bonnefoy, S. Alouani, 1997, European journal of immunology.

Ciliary neurotrophic factor (CNTF): New facets of an old molecule for treating neurodegenerative and metabolic syndrome pathologies.

Mukut Sharma, J. Gauchat, S. Pasquin, 2015, Cytokine & growth factor reviews.

CD23 and B-cell activation.

J. Bonnefoy, J. Gauchat, P. Graber, 1995, Current opinion in immunology.

The interleukin-4/interleukin-13 receptor of human synovial fibroblasts: overexpression of the nonsignaling interleukin-13 receptor alpha2.

B. Schnyder, J. Gauchat, M. Heim, 1998, Laboratory investigation; a journal of technical methods and pathology.

CD21 expressed on basophilic cells is involved in histamine release triggered by CD23 and anti‐CD21 antibodies

J. Bonnefoy, S. Pochon, K. Bacon, 1993, European journal of immunology.

Receptors for IgE.

J. Bonnefoy, G. Mazzei, J. Gauchat, 1993, Current opinion in immunology.

Regulation of Human IgE synthesis

H. Gascan, R. Waal Malefyt, H. Yssel, 1991, Annals of the New York Academy of Sciences.

Anti-CD40 monoclonal antibodies or CD4+ T cell clones and IL-4 induce IgG4 and IgE switching in purified human B cells via different signaling pathways.

H. Gascan, G. Aversa, J. D. de Vries, 1991, Journal of immunology.

Regulation of IgE synthesis by cytokines

H. Gascan, G. Aversa, J. Vries, 1992, Current Biology.

Alpha‐1 antitrypsin up‐regulates human B cell differentiation selectively into IgE‐ and IgG4‐secreting cells

J. Bonnefoy, Y. Delneste, P. Jeannin, 1998, European journal of immunology.

Structure and expression of germline epsilon transcripts in human B cells induced by interleukin 4 to switch to IgE production

R. Coffman, H. Gascan, J. D. de Vries, 1990, The Journal of experimental medicine.

IFN-γ-Mediated Inhibition of Human IgE Synthesis by IL-21 Is Associated with a Polymorphism in the IL-21R Gene1

P. Demoly, V. Boulay, L. Guglielmi, 2006, The Journal of Immunology.

Penta-acylated lipopolisaccharide binds to murine MD-2 but does not induce the oligomerization of TLR4 required for signal transduction.

K. Fukudome, N. Tsuneyoshi, M. Kimoto, 2006, Cellular immunology.

Binding Are Absent in MD-1 MD2 Required for Lipopolysaccharide The Functional and Structural Properties of Masao

K. Fukudome, N. Tsuneyoshi, M. Kimoto, 2004 .

Identification of an alternatively spliced variant of human CD86 mRNA.

J. Bonnefoy, G. Caron, G. Magistrelli, 2001, Biochemical and biophysical research communications.

Soluble CD86 is a costimulatory molecule for human T lymphocytes.

J. Bonnefoy, G. Caron, T. Renno, 2000, Immunity.

CD86 (B7-2) on Human B Cells

J. Bonnefoy, Y. Delneste, P. Jeannin, 1997, The Journal of Biological Chemistry.

The Functional and Structural Properties of MD-2 Required for Lipopolysaccharide Binding Are Absent in MD-11

K. Fukudome, N. Tsuneyoshi, M. Kimoto, 2005, The Journal of Immunology.

A Role for CD147 in Thymic Development

H. Macdonald, J. Bonnefoy, T. Renno, 2002, The Journal of Immunology.

One single burst of SV40 gene expression induces cell proliferation in transforming infection of mouse cells.

É. Khandjian, J. Gauchat, 1988, Oncogene.

Regulation of IgE synthesis by cytokines.

H. Gascan, G. Aversa, J. Vries, 1991 .

Pairs of surface molecules involved in human IgE regulation: CD23-CD21 and CD40-CD40L.

J. Bonnefoy, G. Mazzei, J. Gauchat, 1996, The European respiratory journal. Supplement.

Regulation of Human IgE Synthesis

J. Bonnefoy, J. Gauchat, P. Graber, 1996, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Modulation of IL-4 induced germline ε RNA synthesis in human B cells by tumor necrosis factor-α, anti-CD40 monoclonal antibodies or transforming growth factor-β correlates with levels of IgE production

H. Gascan, G. Aversa, J. Vries, 1992 .

Recombinant Soluble Trimeric CD40 Ligand Is Biologically Active *

A. Durandy, A. Bernard, J. Bonnefoy, 1995, The Journal of Biological Chemistry.

A soluble form of IL-13 receptor alpha 1 promotes IgG2a and IgG2b production by murine germinal center B cells.

G. Elson, J. Gauchat, S. Herren, 1999, Journal of immunology.

CD40 ligand is functionally expressed on human eosinophils

J. Bonnefoy, M. Capron, R. Solari, 1995, European journal of immunology.

T cell clones from an X-linked hyper-immunoglobulin (IgM) patient induce IgE synthesis in vitro despite expression of nonfunctional CD40 ligand

A. Fischer, A. Durandy, J. Bonnefoy, 1994, The Journal of experimental medicine.

Membranes of activated CD4+ T cells expressing T cell receptor (TcR) alpha beta or TcR gamma delta induce IgE synthesis by human B cells in the presence of interleukin-4.

H. Gascan, G. Aversa, J. D. de Vries, 1992, European journal of immunology.

A new pair of surface molecules involved in human IgE regulation.

J. Bonnefoy, S. Pochon, J. Gauchat, 1993, Immunology today.

Inhibition of an in vivo antigen-specific IgE response by antibodies to CD23.

H. Bazin, B. Allet, J. Shields, 1993, Science.

Regulation of germ-line epsilon transcription and induction of epsilon switching in cloned EBV-transformed and malignant human B cell lines by cytokines and CD4+ T cells.

R. de Waal Malefyt, H. Gascan, J. D. de Vries, 1992, Journal of immunology.

Primary human articular chondrocytes, dedifferentiated chondrocytes, and synoviocytes exhibit differential responsiveness to interleukin‐4: Correlation with the expression pattern of the common receptor gamma chain

C. Gabay, P. Guerne, B. Relic, 2002, Journal of cellular physiology.

Thiols decrease human IL-4 production and IL-4-induced immunoglobulin synthesis.

J. Bonnefoy, Y. Delneste, P. Jeannin, 1997, International archives of allergy and immunology.

Human CD40 ligand: molecular cloning, cellular distribution and regulation of IgE synthesis.

M. Peitsch, J. Bonnefoy, G. Mazzei, 1994, Research in immunology.

094 IFN-gamma-mediated inhibition of human IgE synthesis by IL-21 is associated with a polymorphism in the IL-21 R gene

P. Demoly, L. Guglielmi, H. Yssel, 2005 .

CD23 interacts with a new functional extracytoplasmic domain involving N-linked oligosaccharides on CD21.

V. Holers, J. Bonnefoy, S. Pochon, 1994, Journal of immunology.

Regulation of human IgE synthesis: the role of CD4+ and CD8+ T-cells and the inhibitory effects of interferon-alpha.

H. Gascan, J. D. de Vries, M. Roncarolo, 1991, The European respiratory journal. Supplement.

Renal and Hematological Effects of CLCF-1, a B-Cell-Stimulating Cytokine of the IL-6 Family

T. Srivastava, J. Domen, T. Fields, 2015, Journal of immunology research.

Anti-apoptotic potential of several antidiabetic medicinal plants of the eastern James Bay Cree pharmacopeia in cultured kidney cells

P. Haddad, A. Saleem, J. Gauchat, 2018, BMC Complementary and Alternative Medicine.

The ciliary neurotrophic factor receptor α component induces the secretion of and is required for functional responses to cardiotrophin‐like cytokine

S. Chevalier, C. Guillet, H. Gascan, 2001, The EMBO journal.

Human B cell clones can be induced to proliferate and to switch to IgE and IgG4 synthesis by interleukin 4 and a signal provided by activated CD4+ T cell clones

H. Gascan, J. D. de Vries, M. Roncarolo, 1991, The Journal of experimental medicine.

IL-6 activates STAT5 in T cells.

Mukut Sharma, G. Elson, J. Gauchat, 2012, Cytokine.

Cytokine mRNA levels in antigen‐stimulated peripheral blood mononuclear cells

B. Stadler, J. Gauchat, A. D. de Weck, 1989, European journal of immunology.

A novel role for STAT5 in DC

J. Gauchat, A. Tormo, 2013, JAK-STAT.

CLF associates with CLC to form a functional heteromeric ligand for the CNTF receptor complex

S. Chevalier, C. Guillet, H. Gascan, 2000, Nature Neuroscience.

Cytokine-like factor-1, a novel soluble protein, shares homology with members of the cytokine type I receptor family.

L. Menoud, T. Wells, G. Elson, 1998, Journal of immunology.

Signaling Pathways Recruited by the Cardiotrophin-like Cytokine/Cytokine-like Factor-1 Composite Cytokine

S. Chevalier, C. Guillet, H. Gascan, 2001, The Journal of Biological Chemistry.

Effect of human very low-density lipoproteins on cardiotrophin-like cytokine factor 1 (CLCF1) activity

G. Mayer, Mukut Sharma, R. Bossé, 2018, Scientific Reports.

Epstein-Barr virus-induced gene 3 (EBI3) can mediate IL-6 trans-signaling

J. Masson, W. Ferlin, Mukut Sharma, 2017, The Journal of Biological Chemistry.

Functionally active fusion protein of the novel composite cytokine CLC/soluble CNTF receptor.

C. Guillet, H. Gascan, J. Bonnefoy, 2002, European journal of biochemistry.

Induction of human IgE synthesis in B cells by mast cells and basophils

K. Kishi, T. Brunner, J. Bonnefoy, 1993, Nature.

Direct bacterial protein PAMP recognition by human NK cells involves TLRs and triggers alpha-defensin production.

Y. Delneste, N. Thieblemont, P. Jeannin, 2004, Blood.

Cleavage of membrane‐bound CD40 ligand is not required for inducing B cell proliferation and differentiation

J. Bonnefoy, G. Elson, J. Gauchat, 1996, European journal of immunology.

Human Native Soluble CD40L Is a Biologically Active Trimer, Processed Inside Microsomes (*)

J. Bonnefoy, M. Edgerton, G. Elson, 1996, The Journal of Biological Chemistry.

Cutting Edge: IL-21 Is a Switch Factor for the Production of IgG1 and IgG3 by Human B Cells1

D. Foster, V. Boulay, H. Yssel, 2004, The Journal of Immunology.

by Human 3 and IgG 1 the Production of IgG Cutting Edge: IL-21 Is a Switch Factor for

D. Foster, V. Boulay, H. Yssel, 2004 .

CD86 (B7-2) on human B cells. A functional role in proliferation and selective differentiation into IgE- and IgG4-producing cells.

J. Bonnefoy, Y. Delneste, P. Jeannin, 1997, The Journal of biological chemistry.

Structure and functions of CD23.

J. Bonnefoy, P. Jeannin, J. Gauchat, 1997, International reviews of immunology.

Human IgE mRNA expression by peripheral blood lymphocytes stimulated with interleukin 4 and pokeweed mitogen

M. Vogel, B. Stadler, J. Gauchat, 1990, European journal of immunology.

Stimulation of human IgE production by a subset of anti-CD21 monoclonal antibodies: requirement of a co-signal to modulate epsilon transcripts.

J. Bonnefoy, S. Pochon, J. Gauchat, 1994, Immunology.

Involvement of LOX-1 in dendritic cell-mediated antigen cross-presentation.

Kayo Nakamura, T. Sawamura, J. Bonnefoy, 2002, Immunity.

The Composite Cytokine p28/Cytokine-Like Factor 1 Sustains B Cell Proliferation and Promotes Plasma Cell Differentiation

J. Fritz, Mukut Sharma, Jörg H Fritz, 2013, The Journal of Immunology.

The IL-27 p28 Subunit Binds Cytokine-Like Factor 1 to Form a Cytokine Regulating NK and T Cell Activities Requiring IL-6R for Signaling1

W. Ferlin, Angélique Guay-Giroux, R. Lissilaa, 2009, The Journal of Immunology.

Expression of recombinant proteins in a lipid A mutant of Escherichia coli BL21 with a strongly reduced capacity to induce dendritic cell activation and maturation.

S. Chevalier, A. Beck, G. Caron, 2003, JIM - Journal of Immunological Methods.

Expression of biologically active mouse ciliary neutrophic factor (CNTF) and soluble CNTFRalpha in Escherichia coli and characterization of their functional specificities.

S. Chevalier, H. Gascan, Angélique Guay-Giroux, 2004, European cytokine network.

The distribution of IL‐13 receptor α1 expression on B cells, T cells and monocytes and its regulation by IL‐13 and IL‐4

J. Bonnefoy, S. Alouani, G. Elson, 1998, European journal of immunology.

A soluble form of CTLA‐4 generated by alternative splicing is expressed by nonstimulated human T cells

Pascale Jeannin, J. Bonnefoy, G. Magistrelli, 1999, European journal of immunology.

Loss of interleukin-17 receptor D promotes chronic inflammation-associated tumorigenesis

S. Meloche, M. Saba-El-Leil, N. Rivard, 2020, Oncogene.

Cardiotrophin-Like Cytokine Factor 1 Exhibits a Myeloid-Biased Hematopoietic-Stimulating Function

M. Rafei, Mukut Sharma, J. Gauchat, 2019, Front. Immunol..

Cardiotrophin-like cytokine (CLCF1) modulates mesenchymal stem cell osteoblastic differentiation

Mukut Sharma, Sara Nahle, F. Rousseau, 2019, The Journal of Biological Chemistry.

Janus kinase 2/signal transducer and activator of transcription 3 inhibitors attenuate the effect of cardiotrophin-like cytokine factor 1 and human focal segmental glomerulosclerosis serum on glomerular filtration barrier.

T. Srivastava, V. Savin, Mukut Sharma, 2015, Translational research : the journal of laboratory and clinical medicine.

A novel monoclonal antibody, C41, reveals IL‐13Rα1 expression by murine germinal center B cells and follicular dendritic cells

J. Gauchat, S. Herren, P. Graber, 2000 .

Cardiotrophin-like cytokine labelling using Bir A biotin ligase: a sensitive tool to study receptor expression by immune and non-immune cells.

S. Chevalier, H. Gascan, G. Magistrelli, 2005, Journal of immunological methods.

BSMAP, a novel protein expressed specifically in the brain whose gene is localized on chromosome 19p12.

J. Bonnefoy, G. Magistrelli, Y. Delneste, 1999, Biochemical and biophysical research communications.

GPL, a Novel Cytokine Receptor Related to GP130 and Leukemia Inhibitory Factor Receptor*

S. Chevalier, C. Guillet, H. Gascan, 2003, Journal of Biological Chemistry.

Detection of Cytokine mRNA in Polyclonally‐, Antigen‐ or Allergen‐Stimulated Mononuclear Cells

B. Stadler, J. Gauchat, D. Gauchat, 1991, Immunological reviews.

Regulation of IgE synthesis by CD23/CD21 interaction.

J. Bonnefoy, J. Gauchat, P. Graber, 1995, International archives of allergy and immunology.

Two Different Contact Sites Are Recruited by Cardiotrophin-like Cytokine (CLC) to Generate the CLC/CLF and CLC/sCNTFRα Composite Cytokines*

C. Guillet, H. Gascan, M. Chabbert, 2004, Journal of Biological Chemistry.

Stimulation‐dependent lymphokine mRNA levels in human mononuclear cells

B. Stadler, J. Gauchat, A. D. de Weck, 1988, European journal of immunology.

Prototypic Long Pentraxin PTX3 Is Present in Breast Milk, Spreads in Tissues, and Protects Neonate Mice from Pseudomonas aeruginosa Lung Infection

C. Garlanda, A. Mantovani, G. Mancuso, 2013, The Journal of Immunology.

Lymphokine gene expression related to CD4 T cell subset (CD45R/CDw29) phenotype conversion

T. Wyss, W. Pichler, J. Gauchat, 1989, European journal of immunology.

Loss of CD96 Expression as a Marker of HIV-Specific CD8+ T-Cell Differentiation and Dysfunction

D. Kaufmann, C. Tremblay, C. Chartrand-Lefebvre, 2021, Frontiers in Immunology.

The cytokines cardiotrophin-like cytokine/cytokine-like factor-1 (CLC/CLF) and ciliary neurotrophic factor (CNTF) differ in their receptor specificities.

W. Ferlin, Mukut Sharma, R. Lissilaa, 2012, Cytokine.

Inactivation of cardiotrophin-like cytokine, a second ligand for ciliary neurotrophic factor receptor, leads to cold-induced sweating syndrome in a patient.

S. Chevalier, C. Guillet, H. Gascan, 2006, Proceedings of the National Academy of Sciences of the United States of America.

Cloning of MMP-26. A novel matrilysin-like proteinase.

J. Bonnefoy, G. Magistrelli, Y. Delneste, 2000, European journal of biochemistry.

Cyclosporin A prevents induction of the interleukin 2 receptor gene in cultured murine thymocytes.

É. Khandjian, R. Weil, J. Gauchat, 1986, Proceedings of the National Academy of Sciences of the United States of America.

Detection of a polymorphism in exon 8 of the human CD86 gene

R. Bosotti, J. Bonnefoy, G. Magistrelli, 2000, Immunogenetics.

Cytokines of the LIF/CNTF family and metabolism.

Mukut Sharma, J. Gauchat, S. Pasquin, 2016, Cytokine.

Immunoregulatory functions of paf-acether. VIII. Inhibition of IL-4-induced human IgE synthesis in vitro.

R. de Waal Malefyt, J. D. de Vries, É. Vivier, 1992, Journal of immunology.

A soluble form of CTLA‐4 generated by alternative splicing is expressed by nonstimulated human T cells

J. Bonnefoy, G. Magistrelli, Y. Delneste, 1999, European journal of immunology.

J P Aubry, C. Werner‐Favre, R. Zubler, 1994, Immunology.

Identification of Abietic Acid as A Key Component Responsible for The Renal Protective Action of Abies Balsamea, A Medicinal Plant of the Eastern James Bay Cree Pharmacopeia

P. Haddad, J. Arnason, A. Saleem, 2021 .

Brief report: prenatal diagnosis of X-linked hyper-IgM syndrome.

A. Fischer, J. Bonnefoy, G. de Saint Basile, 1994, The New England journal of medicine.

defensin production α TLRs and triggers Direct bacterial protein PAMP recognition by human NK cells involves

Y. Delneste, N. Thieblemont, P. Jeannin, 2013 .

clc is co-expressed with clf or cntfr in developing mouse muscles

H. Gascan, Damien Derouet, O. Delapeyrière, 2005, Cell Communication and Signaling.

Thiols decrease human interleukin (IL) 4 production and IL-4-induced immunoglobulin synthesis

J. Bonnefoy, Y. Delneste, P. Jeannin, 1995, The Journal of experimental medicine.

Cyclosporin A prevents induction of the interleukin 2 receptor gene in cultured murine thymocytes.

R. Weil, J. Gauchat, É. W. Khandjian, 1986, Proceedings of the National Academy of Sciences of the United States of America.

Isolation of Multipotent Stromal Cells from Mouse Bone Marrow

M. Rafei, J. Gauchat, A. Tormo, 2014 .

The Composite Cytokine p28/Cytokine-Like Factor 1 Sustains B Cell Proliferation and Promotes Plasma Cell Differentiation

Mukut Sharma, Jörg H Fritz, G. Elson, 2013, The Journal of Immunology.

Binding to Secreted Bone Matrix in vitro

C. Beauséjour, J. Gauchat, A. Tormo, 2014 .

Promotes Plasma Cell Differentiation Factor 1 Sustains B Cell Proliferation and the Composite Cytokine P28/cytokine-like

G. Elson, J. Gauchat, Sandrine Beaupré, 2022 .