S. Gallion

发表

Chemical genetic approaches to kinase drug discovery.

D. Qian, S. Gallion, 2005, Current opinion in drug discovery & development.

Molecular Dynamics Simulations of Proteins and Protein-Protein Complexes

J. Wampler, D. Stewart, S. Gallion, 1990 .

Discovery of highly potent and selective Bruton's tyrosine kinase inhibitors: Pyridazinone analogs with improved metabolic stability.

Adam R. Johnson, C. Eigenbrot, J. Lubach, 2016, Bioorganic & medicinal chemistry letters.

Modeling Amyloid-Beta as Homogeneous Dodecamers and in Complex with Cellular Prion Protein

S. Gallion, 2012, PloS one.

Specific Btk inhibition suppresses B cell- and myeloid cell-mediated arthritis.

Brandon J. Bravo, L. Diehl, S. Hymowitz, 2011, Nature chemical biology.

Discovery of Potent and Selective Tricyclic Inhibitors of Bruton’s Tyrosine Kinase with Improved Druglike Properties

Adam R. Johnson, C. Eigenbrot, J. Lubach, 2017, ACS medicinal chemistry letters.

Inhibition of human neutrophil elastase. 4. Design, synthesis, X-ray crystallographic analysis, and structure-activity relationships for a series of P2-modified, orally active peptidyl pentafluoroethyl ketones.

H. Schreuder, C. Tardif, N. Peet, 1998, Journal of medicinal chemistry.

Discovery of GS-9973, a selective and orally efficacious inhibitor of spleen tyrosine kinase.

H. Rong, K. Currie, J. Kropf, 2014, Journal of medicinal chemistry.

Imidazo[1,2-a]pyrazine diaryl ureas: inhibitors of the receptor tyrosine kinase EphB4.

D. Brittelli, R. Desimone, K. Currie, 2009, Bioorganic & medicinal chemistry letters.

Potent and selective Bruton's tyrosine kinase inhibitors: discovery of GDC-0834.

S. Hymowitz, J. Lubach, K. Reif, 2015, Bioorganic & medicinal chemistry letters.

Inhibition of oxidosqualene cyclase by substituted quinolizidines

N. Peet, E. Huber, W. Moore, 1994 .

A new class of HIV-1 protease inhibitor: the crystallographic structure, inhibition and chemical synthesis of an aminimide peptide isostere.

R M Stroud, R. Stroud, C. Craik, 1996, Bioorganic & medicinal chemistry.

Temperature-dependent molecular dynamics and restrained X-ray refinement simulations of a Z-DNA hexamer.

P. Weiner, R. Levy, E. Westhof, 1986, Journal of molecular biology.

Interaction of a peptidomimetic aminimide inhibitor with elastase.

G A Petsko, G. Petsko, D. Ringe, 1995, Science.

Molecular mechanics (MM2) calculations on peptides and on the protein Crambin using the CYBER 205

Charles Bender, C. Bender, N. L. Allinger, 1989 .

Discovery of GS-9973, a selective and orally efficacious inhibitor of spleen tyrosine kinase.

H. Rong, K. Currie, J. Kropf, 2014, Journal of medicinal chemistry.

Imidazo[1,2-a]pyrazine diaryl ureas: inhibitors of the receptor tyrosine kinase EphB4.

K. Currie, J. Darrow, D. Pippin, 2009, Bioorganic & medicinal chemistry letters.

Affinity Ligand Selection from a Library of Small Molecules: Assay Development, Screening, and Application

L. Hardy, R. Bhikhabhai, A. Bergenstråhle, 2008, Biotechnology progress.