E. R. Witjas-Paalberends

发表

Gene-specific increase in the energetic cost of contraction in hypertrophic cardiomyopathy caused by thick filament mutations.

A. van Rossum, A. Wilde, A. Lammertsma, 2014, Cardiovascular research.

Challenges and best practices for big data-driven healthcare innovations conducted by profit–non-profit partnerships – a quantitative prioritization

L. H. van de Burgwal, E. Claassen, J. de swart, 2018 .

Chapter 6 A novel HCM mutation in cardiac troponin T primarily alters cross-bridge kinetics and increases the energetic cost of tension generation in human cardiac tissue

C. Poggesi, Steven B Marston, C. Redwood, 2014 .

Phosphorylation of protein kinase C sites Ser42/44 decreases Ca(2+)-sensitivity and blunts enhanced length-dependent activation in response to protein kinase A in human cardiomyocytes.

C. D. dos Remedios, J. van der Velden, P. Wijnker, 2014, Archives of biochemistry and biophysics.

by thick filament mutations

A. Lammertsma, A. Rossum, P. Knaapen, 2014 .

Perturbed Length-Dependent Activation in Human Hypertrophic Cardiomyopathy With Missense Sarcomeric Gene Mutations

F. T. ten Cate, C. D. dos Remedios, C. Poggesi, 2013, Circulation research.

Mutations in MYH7 reduce the force generating capacity of sarcomeres in human familial hypertrophic cardiomyopathy.

S. Heymans, F. T. ten Cate, C. D. dos Remedios, 2013, Cardiovascular research.

GSK3&bgr; Phosphorylates Newly Identified Site in the Proline-Alanine–Rich Region of Cardiac Myosin–Binding Protein C and Alters Cross-Bridge Cycling Kinetics in Human: Short Communication

Jeroen A. A. Demmers, C. D. dos Remedios, S. Sadayappan, 2012, Circulation research.

Familial hypertrophic cardiomyopathy: functional effects of myosin mutation R723G in cardiomyocytes.

B. Brenner, A. Brandis, J. van der Velden, 2013, Journal of molecular and cellular cardiology.

The homozygous K280N troponin T mutation alters cross-bridge kinetics and energetics in human HCM

A. Biggeri, D. Ward, C. D. dos Remedios, 2018, The Journal of general physiology.

Cardiac myosin-binding protein C: hypertrophic cardiomyopathy mutations and structure–function relationships

D. Kuster, J. van der Velden, E. R. Witjas-Paalberends, 2013, Pflügers Archiv - European Journal of Physiology.

ENerGetIcs in hypertrophic cardiomyopathy: traNslation between MRI, PET and cardiac myofilament function (ENGINE study)

J. Marcus, A. Lammertsma, J. Kluin, 2013, Netherlands Heart Journal.

Faster cross‐bridge detachment and increased tension cost in human hypertrophic cardiomyopathy with the R403Q MYH7 mutation

C. Poggesi, Carolyn Y. Ho, M. Michels, 2014, The Journal of physiology.

The HCM-Associated Cardiac Troponin T Mutation K280N Increases the Energetic Cost of Tension Generation in Human Cardiac Myofibrils

C. Poggesi, L. Carrier, C. Redwood, 2013 .

Cardiac myosin-binding protein C: hypertrophic cardiomyopathy mutations and structure–function relationships

D. Kuster, J. van der Velden, E. R. Witjas-Paalberends, 2014, Pflügers Archiv - European Journal of Physiology.

Chapter 4 Positive correlation between contractile dysfunction of the sarcomere and regional systolic strain in hypertrophic cardiomyopathy

A. Schinkel, M. Michels, O. Soliman, 2014 .