H. Widmer

发表

Origin of τ2 and τ2 ridges in 2D NMR spectra and procedures for suppression

Kurt Wüthrich, Gerhard Wagner, Gottfried Otting, 1986 .

Structural basis of guanine nucleotide exchange mediated by the T-cell essential Vav1.

Greg L. Hura, J. Tainer, P. Kuhn, 2008, Journal of molecular biology.

NMR-Solution Structures and Affinities for the Human Somatostatin G-Protein-Coupled Receptors hsst1–5 of CF3 Derivatives of Sandostatin® (Octreotide)

R. R. Ernst, D. Hoyer, D. Seebach, 2009 .

The NMR structure of cyclosporin A bound to cyclophilin in aqueous solution.

K Wüthrich, G. Wider, K. Wüthrich, 1991, Biochemistry.

Receptor-induced conformation change of the immunosuppressant cyclosporin A.

Berthold Von Freyberg, K Wüthrich, G. Wider, 1991, Science.

Three‐dimensional structure of the neurotoxin ATX Ia from Anemonia sulcata in aqueous solution determined by nuclear magnetic resonance spectroscopy

M. Billeter, K. Wüthrich, H. Widmer, 1989, Proteins.

Conformational studies of d-(AAAAATTTTT)2 using constraints from nuclear overhauser effects and from quantitative analysis of the cross-peak fine structures in two-dimensional 1H nuclear magnetic resonance spectra.

K. Wüthrich, W. Denny, W. Chazin, 1989, Biochemistry.

Probing the Helical Secondary Structure of Short‐Chain β‐Peptides

B. Jaun, D. Seebach, Dario Rigo, 1996 .

β‐Peptides: Synthesis by Arndt‐Eistert homologation with concomitant peptide coupling. Structure determination by NMR and CD spectroscopy and by X‐ray crystallography. Helical secondary structure of a β‐hexapeptide in solution and its stability towards pepsin

Ulrich Hommel, D. Seebach, U. Hommel, 1996 .

Matrix-assisted laser desorption and ionization as a mass spectrometric tool for the analysis of poly[(R)-3-hydroxybutanoates]. Comparison with gel permeation chromatography

D. Seebach, H. Widmer, H. Buerger, 1993 .

Synthesis of Tri‐, Penta‐, and Heptapeptides Containing and (R)‐2‐alkyl‐2‐amino‐3‐(methylamino)‐propionic acid residue in the central position

D. Seebach, A. Studer, H. Widmer, 1994 .

Concise and regiospecific syntheses of tri-substituted 1,2,4-triazoles

H. Weber, H. Widmer, E. Dziadulewicz, 1998 .

New Open‐Chain and Cyclic Tetrapeptides, Consisting of α‐, β2‐, and β3‐Amino‐Acid Residues, as Somatostatin Mimics – A Survey

D. Hoyer, B. Jaun, D. Seebach, 2008 .

β2‐ and β3‐Peptides with Proteinaceous Side Chains: Synthesis and solution structures of constitutional isomers, a novel helical secondary structure and the influence of solvation and hydrophobic interactions on folding

B. Jaun, D. Seebach, K. Gademann, 1998 .

"Mixed" β-peptides. A unique helical secondary structure in solution. Preliminary communication

B. Jaun, D. Seebach, K. Gademann, 1997 .

β‐Peptides: Synthesis by Arndt‐Eistert Homologation with Concomitant Peptide Coupling. Structure Determination by NMR and CD Spectroscopy and by X‐Ray Crystallography. Helical Secondary Structure of a β‐Hexapeptide in Solution and Its Stability Towards Pepsin.

D. Seebach, U. Hommel, M. Overhand, 1996 .

Protein NMR in biomedical research

W. Jahnke, W. Jahnke, H. Widmer, 2004, Cellular and Molecular Life Sciences CMLS.

Synthesis, structure and activity of artificial, rationally designed catalytic polypeptides

S. Benner, K. Johnsson, R. Allemann, 1993, Nature.

Use of a double half-filter in two-dimensional proton NMR studies of receptor-bound cyclosporin

G. Wider, K. Wuethrich, C. Weber, 1990 .

The 3D structure of a cyclosporin analogue in water is nearly identical to the cyclophilin‐bound cyclosporin conformation

J. France, A. Widmer, H. Widmer, 1994, FEBS letters.

Structure of human cyclophilin and its binding site for cyclosporin A determined by X-ray crystallography and NMR spectroscopy

G. Wider, K. Wüthrich, M. Walkinshaw, 1991, Nature.

Protein secondary structure determination by NMR Application with recombinant human cyclophilin

G. Wider, K. Wüthrich, K. Memmert, 1991, FEBS letters.

Structural and Biophysical Characterization of the EphB4·EphrinB2 Protein-Protein Interaction and Receptor Specificity*

Manfred Auer, Peter Kuhn, Gye Won Han, 2006, Journal of Biological Chemistry.

Structure and thermodynamic characterization of the EphB4/Ephrin-B2 antagonist peptide complex reveals the determinants for receptor specificity.

P. Kuhn, G. Martiny-Baron, J. Chrencik, 2006, Structure.

The x-ray crystal structure of the first RNA recognition motif and site-directed mutagenesis suggest a possible HuR redox sensing mechanism.

Manfred Auer, Joerg Kallen, Christian Ostermeier, 2010, Journal of molecular biology.

Remedial strategies in structural proteomics: expression, purification, and crystallization of the Vav1/Rac1 complex.

E. Chien, P. Kuhn, J. Chrencik, 2007, Protein expression and purification.

Cyclosporin A—cyclophilin complex formation A model based on X‐ray and NMR data

G. Wider, K. Wüthrich, W. Braun, 1992, FEBS letters.

Determination of the NMR solution structure of the cyclophilin A-cyclosporin A complex

G. Wider, K. Wüthrich, W. Braun, 1994, Journal of biomolecular NMR.

Seamless Insert-Plasmid Assembly at High Efficiency and Low Cost

M. Geiser, M. Auer, C. Ostermeier, 2016, PloS one.

Three-dimensional Structure of the EphB2 Receptor in Complex with an Antagonistic Peptide Reveals a Novel Mode of Inhibition*

R. Abagyan, P. Kuhn, G. Nicola, 2007, Journal of Biological Chemistry.

Simulated two-dimensional nmr cross-peak fine structures for 1H spin systems in polypeptides and polydeoxynucleotides

Kurt Wüthrich, K. Wüthrich, H. Widmer, 1987 .

Improved diagonal suppression in two-dimensional exchange experiments of molecules in the slow motion regime

C. Dalvit, H. Widmer, G. Bovermann, 1990 .

The secondary structure of the toxin ATX Ia from Anemonia sulcata in aqueous solution determined on the basis of complete sequence-specific 1H-NMR assignments.

K. Wüthrich, M. Lazdunski, G. Wagner, 1988, European Journal of Biochemistry.

Simulation of two-dimensional NMR experiments using numerical density matrix calculations

K. Wüthrich, H. Widmer, 1986 .

1H NMR studies of echistatin in solution. Sequential resonance assignments and secondary structure.

C. Dalvit, R. Metternich, H. Widmer, 1991, European journal of biochemistry.

Probing the Helical Secondary Structure of Short-Chain β-Peptides.

B. Jaun, D. Seebach, Dario Rigo, 1997 .

Extensive distance geometry calculations with different NOE calibrations: New criteria for structure selection applied to Sandostatin and BPTI

W. Braun, A. Widmer, H. Widmer, 1993, Journal of biomolecular NMR.