Yajing Liu

发表

Design and biological evaluation of novel 4-(2-fluorophenoxy)quinoline derivatives bearing an imidazolone moiety as c-Met kinase inhibitors.

P. Gong, Zhuang Guo, W. Liao, 2015, Bioorganic & medicinal chemistry.

Design, synthesis and anticancer activity of novel 6-(aminophenyl)-2,4-bismorpholino-1,3,5-triazine derivatives bearing arylmethylene hydrazine moiety

P. Gong, Qiang Huang, Yajing Liu, 2014, Chemical Research in Chinese Universities.

Synthesis and Cytotoxicity Studies of Novel 2‐Hydrazonylpyrido[2,3‐b]pyrazin‐3(4H)‐ones

P. Gong, Yajing Liu, Guogang Zhang, 2012, Archiv der Pharmazie.

Discovery of 4-piperazinyl-2-aminopyrimidine derivatives as dual inhibitors of JAK2 and FLT3.

Yanfang Zhao, Yingxiu Li, Yajing Liu, 2019, European journal of medicinal chemistry.

Discovery of selective EGFR modulator to inhibit L858R/T790M double mutants bearing a N-9-Diphenyl-9H-purin-2-amine scaffold.

Jinxing Hu, P. Gong, Yanfang Zhao, 2018, Bioorganic & medicinal chemistry.

Synthesis and Cytotoxicity of Novel 10-Substituted Dihydroartemisinin Derivatives Containing N-Arylphenyl-ethenesulfonamide Groups

Peng Li, P. Gong, Zijian Liu, 2013, Molecules.

Design, synthesis, and biological activity of novel tetrahydropyrazolopyridone derivatives as FXa inhibitors with potent anticoagulant activity.

L. Gao, P. Gong, Yajing Liu, 2017, Bioorganic & medicinal chemistry.

Synthesis and Biological Evaluation of Novel 6‐Hydrazinyl‐2,4‐bismorpholino pyrimidine and 1,3,5‐Triazine Derivatives as Potential Antitumor Agents

P. Gong, Wufu Zhu, Yanfang Zhao, 2012, Archiv der Pharmazie.

Based on 2-(difluoromethyl)-1-[4,6-di(4-morpholinyl)-1,3,5-triazin-2-yl]-1H-benzimidazole (ZSTK474), design, synthesis and biological evaluation of novel PI3Kα selective inhibitors.

Yu Wang, Yanfang Zhao, Yajing Liu, 2022, Bioorganic chemistry.

Design, synthesis and antibacterial activity of novel pleuromutilin derivatives with thieno[2,3-d]pyrimidine substitution.

Jinxing Hu, Yingxue Li, Yajing Liu, 2022, European journal of medicinal chemistry.

Design, synthesis, and structure-activity relationship of novel and effective apixaban derivatives as FXa inhibitors containing 1,2,4-triazole/pyrrole derivatives as P2 binding element.

P. Gong, Zhuang Guo, Yajing Liu, 2016, Bioorganic & medicinal chemistry.

Synthesis and anti-hepatitis B virus evaluation of novel ethyl 6-hydroxyquinoline-3-carboxylates in vitro.

X. Zhai, P. Gong, Yanfang Zhao, 2008, Bioorganic & medicinal chemistry.

Synthesis and biological evaluation of 1H-benzimidazol-5-ols as potent HBV inhibitors.

P. Gong, Yanfang Zhao, Dong Chen, 2010, Bioorganic & medicinal chemistry letters.

Synthesis and in vitro anti-hepatitis B virus activity of 6H-[1]benzothiopyrano[4,3-b]quinolin-9-ols.

Peng Zhang, P. Gong, Dajun Zhang, 2009, Bioorganic & medicinal chemistry.

Synthesis and Anti‐HBV Activities Evaluation of New Ethyl 8‐Imidazolylmethyl‐7‐hydroxyquinoline‐3‐carboxylate Derivatives in vitro

X. Zhai, P. Gong, Yanfang Zhao, 2008, Archiv der Pharmazie.

Synthesis and antitumor activities of novel 1,4-disubstituted phthalazine derivatives.

P. Gong, Yanfang Zhao, Dong Chen, 2010, European journal of medicinal chemistry.

Design, synthesis and biological evaluation of novel 7-amino-[1,2,4]triazolo[4,3-f]pteridinone, and 7-aminotetrazolo[1,5-f]pteridinone derivative as potent antitumor agents.

Wei Li, P. Gong, Yajing Liu, 2019, European journal of medicinal chemistry.

Synthesis and biological evaluation of novel 2-(2-arylmethylene)hydrazinyl-4-aminoquinazoline derivatives as potent antitumor agents.

X. Zhai, Nan Jiang, P. Gong, 2012, European journal of medicinal chemistry.

Synthesis and Anti‐Hepatitis B Virus Evaluation of 7‐Methoxy‐3‐heterocyclic quinolin‐6‐ols

Zonghui Ma, P. Gong, Zhuang Guo, 2015, Archiv der Pharmazie.

Palladium-catalyzed three-component tandem cyclization of buta-2,3-dien-1-ol, aryl iodides, and imines: an efficient protocol for the synthesis of oxazolidine derivatives

P. Gong, Yanfang Zhao, Yajing Liu, 2017 .

Design, synthesis and pharmacological evaluation of 6,7-disubstituted-4-phenoxyquinoline derivatives as potential antitumor agents.

P. Gong, Yajing Liu, Jianguo Ren, 2014, Bioorganic chemistry.

Design, synthesis and antitumour activity of bisquinoline derivatives connected by 4-oxy-3-fluoroaniline moiety.

Shuang Liu, P. Gong, Qiang Huang, 2013, European journal of medicinal chemistry.

Synthesis and cytotoxicity studies of novel [1,2,4]triazolo[1,5-a]pyrimidine-7-amines.

X. Zhai, Yong Zhang, P. Gong, 2008, Chemical & pharmaceutical bulletin.

Palladium-catalyzed three-component reaction for the synthesis of 3,3-disubstituted allylic alcohols with regio- and stereoselectivity

P. Gong, Gang Hu, Yajing Liu, 2018 .

Design, synthesis and biological evaluation of novel 4-phenoxypyridine based 3-oxo-3,4-dihydroquinoxaline-2-carboxamide derivatives as potential c-Met kinase inhibitors.

Xianglong Zhu, Yajing Liu, Ye Chen, 2020, Bioorganic chemistry.

Efficient Synthesis of trans-3-Amino-1-methylcyclobutan-1-ol

Yajing Liu, Yihang Wei, Fan Yang, 2023, Organic Preparations and Procedures International.

Design, synthesis and biological evaluation of novel 4-phenoxyquinoline derivatives containing 3-oxo-3,4-dihydroquinoxaline moiety as c-Met kinase inhibitors.

P. Gong, Wei Li, Yajing Liu, 2017, Bioorganic & medicinal chemistry.

Design, synthesis and biological evaluation of novel pteridinone derivatives possessing a hydrazone moiety as potent PLK1 inhibitors.

Yanfang Zhao, Yajing Liu, Liangyu Zhu, 2020, Bioorganic & medicinal chemistry letters.

Design, synthesis, and biological evaluation of 4-((6,7-dimethoxyquinoline-4-yl)oxy)aniline derivatives as FLT3 inhibitors for the treatment of acute myeloid leukemia.

P. Gong, Yajing Liu, Le-cun Xu, 2019, Bioorganic & medicinal chemistry letters.

Design, synthesis and biological evaluation of novel aryl-acrylic derivatives as novel indoleamine-2,3-dioxygenase 1 (IDO1) inhibitors.

Di Wu, P. Gong, Yajing Liu, 2019, Bioorganic & medicinal chemistry.

Discovery of novel dual c-Met/HDAC inhibitors as a promising strategy for cancer therapy.

F. Chen, P. Gong, Yajing Liu, 2020, Bioorganic chemistry.

Cell Active Hydroxylactam Inhibitors of Human Lactate Dehydrogenase with Oral Bioavailability in Mice.

Marie Evangelista, BinQing Wei, M. Ultsch, 2016, ACS medicinal chemistry letters.

Optimization of biaryloxazolidinone as promising antibacterial agents against antibiotic-susceptible and antibiotic-resistant gram-positive bacteria.

Yanfang Zhao, Yingxiu Li, Yajing Liu, 2019, European journal of medicinal chemistry.

Design, synthesis and biological evaluation of aminopyrimidine derivatives bearing a 4,5,6,7-tetrahydrothieno [3,2-c]pyridine as potent EGFR inhibitors.

Jinxing Hu, Yue Liu, Yingxue Li, 2021, European journal of medicinal chemistry.

Design, Synthesis and Biological Evaluation of Novel 4-phenoxypyridine Derivatives Containing Semicarbazones Moiety as Potential c-Met Kinase Inhibitors.

Yajing Liu, Jie Li, Ye Chen, 2020, Anti-cancer agents in medicinal chemistry.

2-Aminopyrimidine derivatives as selective dual inhibitors of JAK2 and FLT3 for the treatment of acute myeloid leukemia.

Yanfang Zhao, Yajing Liu, Chen Wang, 2023, Bioorganic chemistry.

Targeting procaspase-3 with WF-208, a novel PAC-1 derivative, causes selective cancer cell apoptosis

Chunfu Wu, Li-hui Wang, Jingyu Yang, 2015, Journal of cellular and molecular medicine.

Discovery of 4-phenylindolines containing a (5-cyanopyridin-3-yl)methoxy moiety as potent inhibitors of the PD-1/PD-L1 interaction.

Shaopeng Zhang, Yajing Liu, Mingze Qin, 2022, Bioorganic & medicinal chemistry letters.

Discovery of [1,2,4]Triazolo[4,3- a]pyridines as Potent Inhibitors Targeting the Programmed Cell Death-1/Programmed Cell Death-Ligand 1 Interaction.

H. Xie, Haotian Zhang, P. Gong, 2019, Journal of medicinal chemistry.

Design, synthesis, and biological evaluation of novel dihydropteridone derivatives possessing oxadiazoles moiety as potent inhibitors of PLK1.

Xinzi He, Yanfang Zhao, Yajing Liu, 2023, European journal of medicinal chemistry.

Discovery of 4-Arylindolines Containing a Thiazole Moiety as Potential Antitumor Agents Inhibiting the Programmed Cell Death-1/Programmed Cell Death-Ligand 1 Interaction.

Li-hui Wang, Haotian Zhang, Yanfang Zhao, 2021, Journal of medicinal chemistry.

Synthesis and antitumor activities of a new series of 4,5-dihydro-1H-thiochromeno[4,3-d]pyrimidine derivatives

X. Zhai, Chun Hu, P. Gong, 2012, Science China Chemistry.

Design and optimization of novel 4-(2-fluorophenoxy)quinoline derivatives bearing a hydrazone moiety as c-Met kinase inhibitors.

X. Ji, Tiemin Sun, P. Gong, 2014, European journal of medicinal chemistry.

Design, synthesis, and evaluation of hydrazones as dual inhibitors of ryanodine receptors and acetylcholinesterases for Alzheimer's disease.

Yajing Liu, Shuanghua Hu, Zihao Zhou, 2023, Bioorganic chemistry.

Design, synthesis and 3D-QSAR analysis of novel 2-hydrazinyl-4-morpholinothieno[3,2-d]pyrimidine derivatives as potential antitumor agents.

X. Zhai, Hongyu Zhou, Di Wu, 2012, European journal of medicinal chemistry.

The adapter protein FADD provides an alternate pathway for entry into the cell cycle by regulating APC/C-Cdh1 E3 ubiquitin ligase activity

Sundaresh Ram, A. Rehemtulla, T. Lawrence, 2023, Journal of Biological Chemistry.

Design, synthesis and biological evaluation of novel N-[4-(2-fluorophenoxy)pyridin-2-yl]cyclopropanecarboxamide derivatives as potential c-Met kinase inhibitors.

Yajing Liu, Ye Chen, Ju Liu, 2020, European journal of medicinal chemistry.

Design, synthesis, and biological evaluation of novel 4‐phenoxypyridine derivatives as potential antitumor agents

Yajing Liu, Ye Chen, Ju Liu, 2019, Archiv der Pharmazie.

Design, synthesis and structure-activity relationships of novel 4-phenoxyquinoline derivatives containing 1,2,4-triazolone moiety as c-Met kinase inhibitors.

Jinxing Hu, P. Gong, Yajing Liu, 2016, European journal of medicinal chemistry.

Design, synthesis, and structure-activity relationships of novel imidazo[4,5-c]pyridine derivatives as potent non-nucleoside inhibitors of hepatitis C virus NS5B.

P. Gong, Yingxiu Li, Yajing Liu, 2018, Bioorganic & medicinal chemistry.

Design, synthesis, and biological activity of novel semicarbazones as potent Ryanodine receptor1 inhibitors of Alzheimer's disease.

Xingxing Ma, S. Lu, Yadong Tang, 2020, Bioorganic & medicinal chemistry.

Discovery and rational design of 2-aminopyrimidine-based derivatives targeting Janus kinase 2 (JAK2) and FMS-like tyrosine kinase 3 (FLT3).

P. Gong, Yanfang Zhao, Yingxiu Li, 2020, Bioorganic chemistry.

Synthesis and biological evaluation of 4,6-diphenyl-2-(1H-pyrrol-1-yl)nicotinonitrile analogues of crolibulin and combretastatin A-4.

Daiying Zuo, Deyu Sun, Yajing Liu, 2018, European journal of medicinal chemistry.

Synthesis and Cytotoxic Evaluation of Some New Phthalazinylpiperazine Derivatives

P. Gong, Yajing Liu, Jianqiang Wang, 2012, Archiv der Pharmazie.

Synthesis and in‐vitro Anti‐hepatitis B Virus Activity of Ethyl 6‐Bromo‐8‐hydroxyimidazo[1,2‐a]pyridine‐3‐carboxylates

P. Gong, Dong Chen, Yajing Liu, 2011, Archiv der Pharmazie.

Design and Synthesis of 1,3,5-Triazines or Pyrimidines Containing Dithiocarbamate Moiety as PI3Kα Selective Inhibitors.

Yanfang Zhao, Yajing Liu, Siyu Fu, 2023, ACS medicinal chemistry letters.

Design, synthesis and biological evaluation of novel pteridinone derivatives as potent dual inhibitors of PLK1 and BRD4

P. Gong, Yanfang Zhao, Yajing Liu, 2020 .

Synthesis and Cytotoxicity Studies of Novel 2‐Hydrazonylpyrido[2,3‐b]pyrazin‐3(4H)‐ones

P. Gong, Yajing Liu, Guogang Zhang, 2012, Archiv der Pharmazie.