R. Kay

发表

Differential membrane binding and diacylglycerol recognition by C1 domains of RasGRPs.

R. Cornell, Joanne E. Johnson, R. Goulding, 2007, The Biochemical journal.

Regulation of RasGRP1 by B cell antigen receptor requires cooperativity between three domains controlling translocation to the plasma membrane.

D. de Jong, R. Goulding, Kira V Anthony, 2007, Molecular biology of the cell.

RasGRP1 Sensitizes an Immature B Cell Line to Antigen Receptor-induced Apoptosis*

R. Kay, Benoit G Guilbault, 2004, Journal of Biological Chemistry.

Complementation of growth factor receptor-dependent mitogenic signaling by a truncated type I phosphatidylinositol 4-phosphate 5-kinase

M. Roussel, C. Rock, R. Ashmun, 1997, Molecular and cellular biology.

Expression cloning of oncogenes by retroviral transfer of cDNA libraries

Robert Kay, R. Kay, I. Whitehead, 1995, Molecular and cellular biology.

Expression of intron-containing C. elegans heat shock genes in mouse cells demonstrates divergence of 3' splice site recognition sequences between nematodes and vertebrates, and an inhibitory effect of heat shock on the mammalian splicing apparatus.

E. Candido, D. Jones, C. Mathias, 1987, Nucleic acids research.

The ETV6-NTRK3 gene fusion encodes a chimeric protein tyrosine kinase that transforms NIH3T3 cells

P. Sorensen, S. Knezevich, D. Wai, 2000, Oncogene.

Cloning and expression of rat liver CTP: phosphocholine cytidylyltransferase: an amphipathic protein that controls phosphatidylcholine synthesis.

R. Aebersold, R. Cornell, R. Kay, 1990, Proceedings of the National Academy of Sciences of the United States of America.

Mechanisms that regulate the cell cycle status of very primitive hematopoietic cells in long-term human marrow cultures. II. Analysis of positive and negative regulators produced by stromal cells within the adherent layer.

C. Eaves, P. Lansdorp, L. Gaboury, 1991, Blood.

Complementation Cloning of NEMO, a Component of the IκB Kinase Complex Essential for NF-κB Activation

G. Courtois, A. Israël, F. Agou, 1998, Cell.

Efficient transcription of a Caenorhabditis elegans heat shock gene pair in mouse fibroblasts is dependent on multiple promoter elements which can function bidirectionally

E. Candido, R. Boissy, R. Kay, 1986, Molecular and cellular biology.

Regulation of RasGRP via a Phorbol Ester-Responsive C1 Domain

C. Der, L. Passmore, C. Tognon, 1998, Molecular and Cellular Biology.

Phosphoinositide 3-Kinase Regulates Plasma Membrane Targeting of the Ras-specific Exchange Factor RasGRP1*

R. Cornell, N. Beaulieu, Ghazaleh Tazmini, 2011, The Journal of Biological Chemistry.

CUL7 is a novel antiapoptotic oncogene.

M. Shago, P. Boutros, I. Jurisica, 2007, Cancer research.

The thrombin receptor, PAR-1, causes transformation by activation of Rho-mediated signaling pathways

C. Der, M. Symons, R. Kay, 2001, Oncogene.

G2A is an oncogenic G protein-coupled receptor

C. Der, M. Symons, I. Zohn, 2000, Oncogene.

Dependence of Dbl and Dbs Transformation on MEK and NF-κB Activation

C. Der, K. Rossman, J. Trzăskos, 1999, Molecular and Cellular Biology.

Complementation cloning of NEMO, a component of the IkappaB kinase complex essential for NF-kappaB activation.

G. Courtois, A. Israël, F. Agou, 1998, Cell.

Transgenic Expression of RasGRP1 Induces the Maturation of Double-Negative Thymocytes and Enhances the Production of CD8 Single-Positive Thymocytes 1

L. Bogatzki, M. Bevan, A. Norment, 2003, The Journal of Immunology.

The RhoA‐ and CDC42‐specific exchange factor Dbs promotes expansion of immature thymocytes and deletion of double‐positive and single‐positive thymocytes

R. Kay, Benoit G Guilbault, M. Klinger, 2004, European journal of immunology.

Retroviral transduction and oncogenic selection of a cDNA encoding Dbs, a homolog of the Dbl guanine nucleotide exchange factor.

R. Kay, I. Whitehead, H. Kirk, 1995, Oncogene.

Dependence of Dbl and Dbs transformation on MEK and NF-kappaB activation.

C. Der, K. Rossman, J. Trzăskos, 1999, Molecular and cellular biology.

Functions of the C-terminal domain of CTP: phosphocholine cytidylyltransferase. Effects of C-terminal deletions on enzyme activity, intracellular localization and phosphorylation potential.

S. Pelech, J. Sanghera, R. Cornell, 1995, The Biochemical journal.

Primary structure and expression of a human CTP:phosphocholine cytidylyltransferase.

R. Cornell, R. Kay, G. Kalmar, 1994, Biochimica et biophysica acta.

Regulate the Cell Cycle Status of Very Primitive Hematopoietic Cells in Long-Term Human Marrow Cultures . 11 . Analysis of Positive and Negative Regulators Produced by Stromal Cells Within the Adherent Layer

C. Eaves, J. Cashman, A. Eaves, 2003 .

Integration of Th17- and Lymphotoxin-Derived Signals Initiates Meningeal-Resident Stromal Cell Remodeling to Propagate Neuroinflammation.

S. Ludwin, A. Bar-Or, L. Boon, 2015, Immunity.

Membrane localization of RasGRP1 is controlled by an EF-hand, and by the GEF domain.

R. Goulding, N. Beaulieu, Ghazaleh Tazmini, 2009, Biochimica et biophysica acta.

Single-Positive Thymocytes Thymocytes and Enhances the Production of the Maturation of Double-Negative Transgenic Expression of RasGRP 1 Induces

L. Bogatzki, M. Bevan, A. Norment, 2003 .

Structure, expression, and evolution of a heat shock gene locus in Caenorhabditis elegans that is flanked by repetitive elements.

E. Candido, D. Jones, R. Kay, 1986, The Journal of biological chemistry.

Nucleic Acids Research

Donald Jones, E. Candido, R. Kay, 2011, Nucleic Acids Research.

Deregulated expression of RasGRP1 initiates thymic lymphomagenesis independently of T-cell receptors

R. Goulding, R. Kay, Benoit G Guilbault, 2005, Oncogene.

Expression of Thy-1 on human hematopoietic progenitor cells

P. Lansdorp, R. Kay, R. Cutler, 1993, The Journal of experimental medicine.

Structure, organization, and expression of the 16-kDa heat shock gene family of Caenorhabditis elegans.

D. Dixon, R. Graham, E. Candido, 1989, Genome.