H. Fukuda

发表

Analysis of the non-covalent interaction between metal ions and the cysteine-rich domain of protein kinase C eta by electrospray ionization mass spectrometry.

H. Ohigashi, K. Irie, M. Shindo, 2003, Bioorganic & medicinal chemistry.

Establishment of a binding assay for protein kinase C isozymes using synthetic C1 peptides and development of new medicinal leads with protein kinase C isozyme and C1 domain selectivity.

U. Kikkawa, H. Konishi, H. Ohigashi, 2002, Pharmacology & therapeutics.

Toward the identification of selective modulators of protein kinase C (PKC) isozymes: establishment of a binding assay for PKC isozymes using synthetic C1 peptide receptors and identification of the critical residues involved in the phorbol ester binding.

U. Kikkawa, H. Konishi, H. Ohigashi, 2001, Bioorganic & medicinal chemistry.

Synthesis and phorbol ester-binding studies of the individual cysteine-rich motifs of protein kinase D.

U. Kikkawa, H. Konishi, H. Ohigashi, 1999, Bioorganic & medicinal chemistry letters.

Solid-phase synthesis, mass spectrometric analysis of the zinc-folding, and phorbol ester-binding studies of the 116-mer peptide containing the tandem cysteine-rich C1 domains of protein kinase C gamma.

H. Ohigashi, K. Irie, P. Wender, 1999, Bioorganic & medicinal chemistry.

Synthesis and binding studies of the 116-mer peptide containing the double cysteine-rich motifs of protein kinase C gamma

H. Ohigashi, K. Irie, P. Wender, 1998 .

The toxic conformation of the 42-residue amyloid beta peptide and its relevance to oxidative stress in Alzheimer's disease.

M. Nagao, T. Shirasawa, H. Ohigashi, 2007, Mini reviews in medicinal chemistry.

Synthesis, aggregation, and neurotoxicity of the Alzheimer's Abeta1-42 amyloid peptide and its isoaspartyl isomers.

T. Shirasawa, Takahiko Shimizu, H. Mori, 1999, Bioorganic & medicinal chemistry letters.

Isolation, identification, and biological evaluation of Nrf2-ARE activator from the leaves of green perilla (Perilla frutescens var. crispa f. viridis).

A. Akaike, H. Sugimoto, K. Irie, 2012, Free radical biology & medicine.

Molecular Basis for Protein Kinase C Isozyme-Selective Binding: The Synthesis, Folding, and Phorbol Ester Binding of the Cysteine-Rich Domains of All Protein Kinase C Isozymes

U. Kikkawa, H. Konishi, H. Ohigashi, 1998 .

Affinity purification method using a reversible biotinylating reagent for peptides synthesized by the solid-phase technique

N. Fujii, S. Funakoshi, H. Fukuda, 1993 .

Stimulatory effects of islet amyloid polypeptide (amylin) on exocrine pancreas and gastrin release in conscious rats

K. Kitani, A. Funakoshi, S. Funakoshi, 1992, Regulatory Peptides.

Isoaspartate formation at position 23 of amyloid beta peptide enhanced fibril formation and deposited onto senile plaques and vascular amyloids in Alzheimer's disease

Shigeo Murayama, T. Shirasawa, Takahiko Shimizu, 2002, Journal of neuroscience research.

Identification of peptides mimicking the antigenicity and immunogenicity of conformational epitopes on Japanese encephalitis virus protein using synthetic peptide libraries.

H. Fukuda, J. Kimura, Y. Hirabayashi, 1996, Journal of virological methods.

Chemoselective one-step purification method for peptides synthesized by the solid-phase technique.

N. Fujii, S. Funakoshi, H. Fukuda, 1991, Proceedings of the National Academy of Sciences of the United States of America.

Identification of the binding site of 55kDa tumor necrosis factor receptor by synthetic peptides.

H. Kikuchi, H. Hemmi, H. Fukuda, 1992, Biochemical and biophysical research communications.

Analysis of the Secondary Structure of β-Amyloid (Aβ42) Fibrils by Systematic Proline Replacement*

M. Nagao, T. Shirasawa, Takahiko Shimizu, 2004, Journal of Biological Chemistry.

Analysis of the secondary structure of beta-amyloid (Abeta42) fibrils by systematic proline replacement.

M. Nagao, T. Shirasawa, Takahiko Shimizu, 2004, The Journal of biological chemistry.