P. Lorenzo

发表

Iridals are a novel class of ligands for phorbol ester receptors with modest selectivity for the RasGRP receptor subfamily.

I. Enyedy, P. Blumberg, J. Stone, 2001, Journal of medicinal chemistry.

The Exchange Factor and Diacylglycerol Receptor RasGRP3 Interacts with Dynein Light Chain 1 through Its C-terminal Domain*

P. Lorenzo, S. Okamura, Carolyn E Oki-Idouchi, 2006, Journal of Biological Chemistry.

Structural basis of binding of high-affinity ligands to protein kinase C: prediction of the binding modes through a new molecular dynamics method and evaluation by site-directed mutagenesis.

I. Enyedy, P. Blumberg, S. Wang, 2001, Journal of medicinal chemistry.

Structural Basis of Binding of High-Affinity Ligands to Protein Kinase C: Prediction of the Binding Modes Through a New Molecular Dynamics Method and Evaluation by Site-Directed Mutagenesis.

Youngshang Pak, I. Enyedy, Shaomeng Wang, 2001 .

Differential selectivity of ligands for the C1a and C1b phorbol ester binding domains of protein kinase Cdelta: possible correlation with tumor-promoting activity.

Z. Szallasi, P. Blumberg, G. Wagner, 1998, Cancer research.

Effects of the in vitro treatment with gangliosides on the release of endogenous amino acids from rat hypoxic atria.

P. Lorenzo, M. Otero-Losada, E. Adler-Graschinsky, 1995, Journal of autonomic pharmacology.

RasGRP1 Is Essential for Ras Activation by the Tumor Promoter 12-O-Tetradecanoylphorbol-13-acetate in Epidermal Keratinocytes

J. Stone, N. Dower, P. Lorenzo, 2010, The Journal of Biological Chemistry.

Potential Role of Granulocyte Colony-Stimulating Factor

J. Stone, J. Cline, N. Dower, 2009 .

RasGRP1 transgenic mice develop cutaneous squamous cell carcinomas in response to skin wounding: potential role of granulocyte colony-stimulating factor.

J. Stone, J. Cline, N. Dower, 2009, The American journal of pathology.

Differential effects of bryostatin 1 and 12-O-tetradecanoylphorbol-13-acetate on the regulation and activation of RasGRP1 in mouse epidermal keratinocytes

Matthew C. Tuthill, P. Lorenzo, Carolyn E Oki, 2006, Molecular Cancer Therapeutics.

RasGRP1 Represents a Novel Non-protein Kinase C Phorbol Ester Signaling Pathway in Mouse Epidermal Keratinocytes*

P. Blumberg, J. Stone, P. Lorenzo, 2003, Journal of Biological Chemistry.

Phosphorylation of Protein Kinase Cδ on Distinct Tyrosine Residues Regulates Specific Cellular Functions*

P. Blumberg, S. Garfield, C. Brodie, 2000, The Journal of Biological Chemistry.

Protein Kinase Cδ Targets Mitochondria, Alters Mitochondrial Membrane Potential, and Induces Apoptosis in Normal and Neoplastic Keratinocytes When Overexpressed by an Adenoviral Vector

Luowei Li, S. Yuspa, P. Blumberg, 1999, Molecular and Cellular Biology.

Protein kinase Calpha and protein kinase Cdelta play opposite roles in the proliferation and apoptosis of glioma cells.

F. Umansky, P. Blumberg, C. Brodie, 2001, Cancer research.

Protein Kinase Cα and Protein Kinase Cδ Play Opposite Roles in the Proliferation and Apoptosis of Glioma Cells

F. Umansky, P. Blumberg, C. Brodie, 2001 .

Modulating protein kinase C (PKC) to increase the efficacy of chemotherapy: stepping into darkness.

P. Dennis, P. Lorenzo, 2003, Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy.

Targeted deletion of RasGRP1 impairs skin tumorigenesis.

Junfang Ji, J. Ramos, J. Stone, 2014, Carcinogenesis.

Involvement of monoamine oxidase and noradrenaline uptake in the positive chronotropic effects of apigenin in rat atria.

J. Medina, P. Lorenzo, E. Adler-Graschinsky, 1996, European journal of pharmacology.

The Catalytic Domain of Protein Kinase Cδ Confers Protection from Down-regulation Induced by Bryostatin 1*

P. Blumberg, P. Ács, G. Pettit, 1997, The Journal of Biological Chemistry.

The guanine nucleotide exchange factor RasGRP is a high -affinity target for diacylglycerol and phorbol esters.

P. Blumberg, J. Stone, M. Beheshti, 2000, Molecular pharmacology.

Phorbol esters as probes for the study of protein kinase C function.

M. Kazanietz, P. Lorenzo, 2003, Methods in molecular biology.

Gangliosides prevent the dimethyl sulphoxide-induced increases in [3H]-noradrenaline release from rat isolated atria.

P. Lorenzo, E. Adler-Graschinsky, 1992, Journal of autonomic pharmacology.

Phorbol esters modulate the Ras exchange factor RasGRP3.

P. Blumberg, J. Stone, D. Bottorff, 2001, Cancer research.

Prostanoid production in hypoxic rat isolated atria: influence of acute diabetes.

P. Lorenzo, E. Adler-Graschinsky, H. Peredo, 1994, Prostaglandins, leukotrienes, and essential fatty acids.

Differential roles of the tandem C1 domains of protein kinase C delta in the biphasic down-regulation induced by bryostatin 1.

P. Blumberg, S. Garfield, G. Pettit, 1999, Cancer research.

Inhibitors of Protein Kinase C and Related Receptors for the Lipophilic Second-Messenger sn-1,2-Diacylglycerol

P. Blumberg, P. Ács, P. Lorenzo, 2000 .

Protein Kinase C δ (PKCδ) Inhibits the Expression of Glutamine Synthetase in Glial Cells via the PKCδ Regulatory Domain and Its Tyrosine Phosphorylation*

P. Blumberg, C. Brodie, P. Ács, 1998, The Journal of Biological Chemistry.

Structural basis of RasGRP binding to high-affinity PKC ligands.

I. Enyedy, Shaomeng Wang, P. Blumberg, 2002, Journal of medicinal chemistry.

Both the Catalytic and Regulatory Domains of Protein Kinase C Chimeras Modulate the Proliferative Properties of NIH 3T3 Cells*

Z. Szallasi, P. Blumberg, J. Mushinski, 1997, The Journal of Biological Chemistry.

RasGRP1 overexpression in the epidermis of transgenic mice contributes to tumor progression during multistage skin carcinogenesis.

J. Cline, P. Lorenzo, Carolyn E Oki-Idouchi, 2007, Cancer research.

Skin Carcinogenesis Mice Contributes to Tumor Progression during Multistage RasGRP 1 Overexpression in the Epidermis of Transgenic

J. Cline, P. Lorenzo, Carolyn E Oki-Idouchi, 2007 .

Transgenic overexpression of RasGRP1 in mouse epidermis results in spontaneous tumors of the skin.

P. Lorenzo, Carolyn E Oki-Idouchi, 2007, Cancer research.

Possible participation of nitric oxide in the increase of norepinephrine release caused by angiotensin peptides in rat atria.

P. Lorenzo, E. Adler-Graschinsky, M. Gironacci, 1997, Hypertension.

The Catalytic Domain of Protein Kinase C Chimeras Modulates the Affinity and Targeting of Phorbol Ester-induced Translocation*

Z. Szallasi, P. Blumberg, T. Bíró, 1997, The Journal of Biological Chemistry.

Comparison of the roles of the C1a and C1b domains of protein kinase C alpha in ligand induced translocation in NIH 3T3 cells

Z. Szallasi, P. Blumberg, G. Wagner, 1999, FEBS letters.

Effects of L-glutamate on the responses to nerve stimulation in rat isolated atria.

N. Butta, P. Lorenzo, E. Adler-Graschinsky, 1994, European journal of pharmacology.

Relaxant effects of benzodiazepines on isolated human umbilical arteries and veins

A. Elgoyhen, R. Rothlin, P. Lorenzo, 1993 .

Relaxant effects of beta-carbolines on rat aortic rings.

P. Lorenzo, E. Adler-Graschinsky, B. Elgoyhen, 1992, The Journal of pharmacology and experimental therapeutics.

Different Interactions of Citalopram with the Prejunctional Effects of Serotonin in Peripheral Tissues

A. Elgoyhen, N. Butta, P. Lorenzo, 1991 .