C. George

发表

Conformationally Constrained Analogues of Diacylglycerol. Part 12. Ultrapotent Protein Kinase C Ligands Based on a Chiral 4,4‐ Disubstituted Heptono‐1,4‐lactone Template.

Z. Szallasi, G. Milne, Jeewoo Lee, 1996 .

Chemistry and pharmacology of the piperidine-based analogues of cocaine. Identification of potent DAT inhibitors lacking the tropane skeleton.

C. George, J. Flippen-Anderson, A. Kozikowski, 1998, Journal of medicinal chemistry.

STRUCTURE-BASED DESIGN OF A NEW CLASS OF PROTEIN KINASE C MODULATORS

Shaomeng Wang, P. Blumberg, L. Qiao, 1998 .

Tumor Targeting with Novel Pyridyl 6-Substituted Pyrrolo[2,3- d]Pyrimidine Antifolates via Cellular Uptake by Folate Receptor α and the Proton-Coupled Folate Transporter and Inhibition of De Novo Purine Nucleotide Biosynthesis.

L. Matherly, Z. Hou, L. Polin, 2018, Journal of medicinal chemistry.

Dual Targeting of Epithelial Ovarian Cancer Via Folate Receptor α and the Proton-Coupled Folate Transporter with 6-Substituted Pyrrolo[2,3-d]pyrimidine Antifolates

L. Matherly, Z. Hou, L. Polin, 2017, Molecular Cancer Therapeutics.

Novel 5-substituted pyrrolo[2,3-d]pyrimidines as dual inhibitors of glycinamide ribonucleotide formyltransferase and 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase and as potential antitumor agents.

L. Matherly, Z. Hou, Sudhir Raghavan, 2015, Journal of medicinal chemistry.

Structure–Activity Profiles of Novel 6-Substituted Pyrrolo[2,3-d]pyrimidine Thienoyl Antifolates with Modified Amino Acids for Cellular Uptake by Folate Receptors α and β and the Proton-Coupled Folate Transporter

L. Matherly, Z. Hou, Sudhir Raghavan, 2014, Journal of medicinal chemistry.

Novel N-substituted 3 alpha-[bis(4'-fluorophenyl)methoxy]tropane analogues: selective ligands for the dopamine transporter.

R. H. Kline, A. Newman, J. Katz, 1997, Journal of medicinal chemistry.

Novel 4'-substituted and 4',4"-disubstituted 3 alpha-(diphenylmethoxy)tropane analogs as potent and selective dopamine uptake inhibitors.

R. H. Kline, A. Newman, J. Katz, 1995, Journal of medicinal chemistry.

Medetomidine analogs as alpha 2-adrenergic ligands. 2. Design, synthesis, and biological activity of conformationally restricted naphthalene derivatives of medetomidine.

J. Dalton, D. Miller, D. Feller, 1996, Journal of medicinal chemistry.

Conformationally constrained phosphotyrosyl mimetics designed as monomeric Src homology 2 domain inhibitors.

S. Shoelson, T. Burke, J. Barchi, 1995, Journal of medicinal chemistry.

Novel conformationally constrained tropane analogues by 6-endo-trig radical cyclization and stille coupling - switch of activity toward the serotonin and/or norepinephrine transporter.

J. Flippen-Anderson, A. Kozikowski, K. Johnson, 2000, Journal of medicinal chemistry.

Highly selective chiral N-substituted 3alpha-[bis(4'-fluorophenyl)methoxy]tropane analogues for the dopamine transporter: synthesis and comparative molecular field analysis.

A. Newman, T. Kopajtic, J. Katz, 2000, Journal of medicinal chemistry.

Studies in polyphenol chemistry and bioactivity. 2. Establishment of interflavan linkage regio- and stereochemistry by oxidative degradation of an O-alkylated derivative of procyanidin B2 to (R)-(-)-2,4-diphenylbutyric acid.

C. George, A. Kozikowski, C. George, 2000, The Journal of organic chemistry.

2-Carbomethoxy-3-aryl-8-bicyclo[3.2.1]octanes: potent non-nitrogen inhibitors of monoamine transporters.

Z. Chen, B. Madras, P. Meltzer, 1997, Journal of medicinal chemistry.

6-Substituted Pyrrolo[2,3-d]pyrimidine Thienoyl Regioisomers as Targeted Antifolates for Folate Receptor α and the Proton-Coupled Folate Transporter in Human Tumors.

C. Dann, L. Matherly, Z. Hou, 2015, Journal of medicinal chemistry.

Conformationally constrained analogues of diacylglycerol. 12. Ultrapotent protein kinase C ligands based on a chiral 4,4-disubstituted heptono-1,4-lactone template.

Z. Szallasi, G. Milne, P. Blumberg, 1996, Journal of medicinal chemistry.

Resolution and adrenergic activities of the optical isomers of 4-[1-(1-naphthyl)ethyl]-1H-imidazole.

R. A. Lyon, D. Miller, K. Romstedt, 1992, Chirality.

Synthesis of 2-exo- and 2-endo-mecamylamine analogues. Structure-activity relationships for nicotinic antagonism in the central nervous system.

B. Martin, C. George, E. May, 1991, Journal of medicinal chemistry.

Synthesis of 6- and 7- hydroxy-8-azabicyclo[3.2.1]octanes and their binding affinity for the dopamine and serotonin transporters.

Z. Chen, M. Jayaraman, B. Madras, 2001, Journal of Medicinal Chemistry.

Slow-onset, long-duration 3-(3',4'-dichlorophenyl)-1-indanamine monoamine reuptake blockers as potential medications to treat cocaine abuse.

M. Froimowitz, J. Jurayj, E. Gardner, 2000, Journal of medicinal chemistry.

Synthesis, optical resolution, absolute configuration, and preliminary pharmacology of (+)- and (-)-cis-2,3,3a,4,5,9b-hexahydro-1-methyl-1H- pyrrolo-[3,2-h]isoquinoline, a structural analog of nicotine.

B. Martin, C. George, E. May, 1993, Journal of medicinal chemistry.

Structure-activity relationships at monoamine transporters and muscarinic receptors for N-substituted-3alpha-(3'-chloro-, 4'-chloro-, and 4',4''-dichloro-substituted-diphenyl)methoxytropanes.

A. Newman, T. Kopajtic, J. Katz, 2001, Journal of medicinal chemistry.