A. B. Shaik

发表

Design, synthesis and biological evaluation of 1, 4-dihydro indeno[1,2-c] pyrazole linked oxindole analogues as potential anticancer agents targeting tubulin and inducing p53 dependent apoptosis.

Venkata Krishna Kanth Makani, A. Kamal, M. Pal-Bhadra, 2018, European journal of medicinal chemistry.

Novel Dual-Target μ-Opioid Receptor and Dopamine D3 Receptor Ligands as Potential Nonaddictive Pharmacotherapeutics for Pain Management.

V. Katritch, A. Newman, Alessandro Bonifazi, 2021, Journal of medicinal chemistry.

The highly selective dopamine D 3 R antagonist, R-VK4-40 attenuates oxycodone reward and augments analgesia in rodents

Z. Xi, A. Newman, C. Jordan, 2019, Neuropharmacology.

Synthesis and biological evaluation of novel pyrano[3,2-c]carbazole derivatives as anti-tumor agents inducing apoptosis via tubulin polymerization inhibition.

Nibedita Patel, P. Dubey, B. V. Subba Reddy, 2015, Organic & biomolecular chemistry.

Discovery of pyrrolospirooxindole derivatives as novel cyclin dependent kinase 4 (CDK4) inhibitors by catalyst-free, green approach.

A. Kamal, V. L. Nayak, K. S. Babu, 2016, European journal of medicinal chemistry.

Synthesis, biological evaluation of new oxazolidino-sulfonamides as potential antimicrobial agents.

A. Kamal, A. B. Shaik, P. Swapna, 2013, European journal of medicinal chemistry.

Synthesis of new bis‐pyrazole linked hydrazides and their in vitro evaluation as antimicrobial and anti‐biofilm agents: A mechanistic role on ergosterol biosynthesis inhibition in Candida albicans

A. Kamal, C. Kumar, Irfan Khan, 2019, Chemical biology & drug design.

Pyrazole-oxadiazole conjugates: synthesis, antiproliferative activity and inhibition of tubulin polymerization.

N. Jain, A. Kamal, Sowjanya Polepalli, 2014, Organic & biomolecular chemistry.

Design, synthesis and biological evaluation of imidazopyridine/imidazopyrimidine-benzimidazole conjugates as potential anticancer agents

V. L. Nayak, A. Kamal, Gajjela Bharath Kumar, 2015 .

A highly D3R-selective and efficacious partial agonist (S)-ABS01-113 compared to its D3R-selective antagonist enantiomer (R)-ABS01-113 as potential treatments for opioid use disorder

A. Janowsky, Z. Xi, A. Newman, 2022, Neuropsychopharmacology.

Synthesis of arylpyrazole linked benzimidazole conjugates as potential microtubule disruptors.

N. Jain, Sowjanya Polepalli, A. Kamal, 2015, Bioorganic & medicinal chemistry.

Synthesis of β-carboline-benzimidazole conjugates using lanthanum nitrate as a catalyst and their biological evaluation.

M. N. Rao, N. Nagesh, A. Kamal, 2014, Organic & biomolecular chemistry.

Synthesis, biological evaluation, and molecular modeling of (E)-2-aryl-5-styryl-1,3,4-oxadiazole derivatives as acetylcholine esterase inhibitors

G. N. Sastry, A. Kamal, C. Kumar, 2013, Medicinal Chemistry Research.

Metabolic profiling and biological activities of bioactive compounds produced by Pseudomonas sp. strain ICTB-745 isolated from Ladakh, India.

A. Kamal, C. Kumar, J. Joseph, 2012, Journal of microbiology and biotechnology.

[O-methyl-11C]N-(4-(4-(3-Chloro-2-methoxyphenyl)-piperazin-1-yl)butyl)-1H-indole-2-carboxamide ([11C]BAK4-51) Is an Efflux Transporter Substrate and Ineffective for PET Imaging of Brain D3 Receptors in Rodents and Monkey

S. Zoghbi, J. Liow, R. Gladding, 2018, Molecules.

A highly D3R-selective and efficacious partial agonist (S)-ABS01-113 compared to its D3R-selective antagonist enantiomer (R)-ABS01-113 as potential treatments for opioid use disorder

A. Janowsky, Z. Xi, A. Newman, 2022, Neuropsychopharmacology.

Synthesis of imidazo[2,1-b][1,3,4]thiadiazole–chalcones as apoptosis inducing anticancer agents

A. Kamal, Gajjela Bharath Kumar, A. B. Shaik, 2014 .

Statistical optimization of production conditions of β-glucosidase from Bacillus stratosphericus strain SG9

C. Ganesh Kumar, A. Kamal, A. B. Shaik, 2017, 3 Biotech.

Design and synthesis of imidazo[2,1-b]thiazole linked triazole conjugates: Microtubule-destabilizing agents.

A. Kamal, K. S. Babu, A. S. Rao, 2017, European journal of medicinal chemistry.

L-Proline mediated synthesis of quinoxalines; evaluation of cytotoxic and antimicrobial activity

Shaikh Faazil, A. Kamal, K. S. Babu, 2014 .

New Quinoline Linked Chalcone and Pyrazoline Conjugates: Molecular Properties Prediction, Antimicrobial and Antitubercular Activities

A. Kamal, A. Alarifi, A. S. Rao, 2017 .

Design and synthesis of pyrazole-oxindole conjugates targeting tubulin polymerization as new anticancer agents.

N. Jain, A. Kamal, R. Mishra, 2015, European journal of medicinal chemistry.

Synthesis of (Z)-(arylamino)-pyrazolyl/isoxazolyl-2-propenones as tubulin targeting anticancer agents and apoptotic inducers.

N. Jain, A. Kamal, Sowjanya Polepalli, 2015, Organic & biomolecular chemistry.

Synthesis of 2-anilinopyridine–arylpropenone conjugates as tubulin inhibitors and apoptotic inducers

N. Jain, A. Kamal, Gajjela Bharath Kumar, 2015 .

Identification, characterization and evaluation of novel antifungal cyclic peptides from Neobacillus drentensis.

Ramars Amanchy, A. Kamal, Ganesh Kumar Chityala, 2021, Bioorganic chemistry.

L‐Proline Mediated Synthesis of Quinoxalines; Evaluation of Cytotoxic and Antimicrobial Activity.

Shaikh Faazil, A. Kamal, K. S. Babu, 2015 .

Design and synthesis of pyrazole/isoxazole linked arylcinnamides as tubulin polymerization inhibitors and potential antiproliferative agents.

N. Jain, A. Kamal, B. B. Rao, 2015, Organic & biomolecular chemistry.

Induction of apoptosis in lung carcinoma cells by antiproliferative cyclic lipopeptides from marine algicolous isolate Bacillus atrophaeus strain AKLSR1

C. Ganesh Kumar, C. Kumar, S. Prabhakar, 2019, Process Biochemistry.

Synthesis of phenstatin/isocombretastatin-chalcone conjugates as potent tubulin polymerization inhibitors and mitochondrial apoptotic inducers.

A. Kamal, Gajjela Bharath Kumar, A. B. Shaik, 2015, Organic & biomolecular chemistry.

Design, synthesis of phenstatin/isocombretastatin-oxindole conjugates as antimitotic agents.

A. Kamal, Gajjela Bharath Kumar, A. B. Shaik, 2016, Bioorganic & medicinal chemistry.

Design and Synthesis of Aminostilbene–Arylpropenones as Tubulin Polymerization Inhibitors

N. Jain, A. Kamal, Sowjanya Polepalli, 2014, ChemMedChem.

Anti-tubercular agents. Part 7: a new class of diarylpyrrole-oxazolidinone conjugates as antimycobacterial agents.

A. Kamal, I. Khan, N. Kalia, 2013, European journal of medicinal chemistry.

Design, synthesis and biological evaluation of novel pyrazolochalcones as potential modulators of PI3K/Akt/mTOR pathway and inducers of apoptosis in breast cancer cells.

A. Kamal, C. Kumar, Gajjela Bharath Kumar, 2017, European journal of medicinal chemistry.

Design, synthesis, in silico pharmacokinetics prediction and biological evaluation of 1,4-dihydroindeno[1,2-c]pyrazole chalcone as EGFR /Akt pathway inhibitors.

A. Kamal, Aravind Setti, C. Kumar, 2019, European journal of medicinal chemistry.

Synthesis and Biological Evaluation of Imidazopyridine–Oxindole Conjugates as Microtubule‐Targeting Agents

A. Kamal, A. Nagabhushana, K. Ramakrishna, 2013, ChemMedChem.

Structure Activity Relationships for a Series of Eticlopride-Based Dopamine D2/D3 Receptor Bitopic Ligands.

Lei Shi, A. Newman, Alessandro Bonifazi, 2021, Journal of medicinal chemistry.

Newly Developed Dopamine D3 Receptor Antagonists, R-VK4-40 and R-VK4-116, Do Not Potentiate Cardiovascular Effects of Cocaine or Oxycodone in Rats

Z. Xi, E. Thorndike, A. Newman, 2019, The Journal of Pharmacology and Experimental Therapeutics.

Investigation of novel primary and secondary pharmacophores, and 3-substitution in the linking chain of a series of highly selective and bitopic dopamine D3 receptor antagonists and partial agonists.

Z. Xi, A. Newman, Alessandro Bonifazi, 2019, Journal of medicinal chemistry.

The Significance of Chirality in Drug Design and Synthesis of Bitopic Ligands as D3 Receptor (D3R) Selective Agonists.

A. Newman, Alessandro Bonifazi, Gregory H. Imler, 2019, Journal of medicinal chemistry.

Dopamine D3/D2 Receptor Ligands Based on Cariprazine for the Treatment of Psychostimulant Use Disorders That May Be Dual Diagnosed with Affective Disorders.

J. R. Lane, Z. Xi, A. Newman, 2023, Journal of medicinal chemistry.

Synthesis, biological evaluation, and molecular modeling of (E)-2-aryl-5-styryl-1,3,4-oxadiazole derivatives as acetylcholine esterase inhibitors

G. N. Sastry, C. Kumar, A. Kamal, 2013, Medicinal Chemistry Research.

Beyond small-molecule SAR: Using the dopamine D3 receptor crystal structure to guide drug design

Z. Xi, A. Newman, Guo-hua Bi, 2018 .