Jian-zhong Chen

发表

Cyclin-dependent kinase-2 as a target for cancer therapy: progress in the development of CDK2 inhibitors as anti-cancer agents.

Tahir Ali Chohan, Jian-Zhong Chen, T. Chohan, 2014, Current medicinal chemistry.

Molecular simulation studies on the binding selectivity of 2-anilino-4-(thiazol-5-yl)-pyrimidines in complexes with CDK2 and CDK7.

T. Chohan, Haiyan Qian, You-lu Pan, 2016, Molecular bioSystems.

Design, syntheses, structure-activity relationships and docking studies of coumarin derivatives as novel selective ligands for the CB2 receptor.

Xin Xie, Xin Xie, Hai-Yan Qian, 2015, European journal of medicinal chemistry.

The agonist binding mechanism of human CB2 receptor studied by molecular dynamics simulation, free energy calculation and 3D-QSAR studies.

Jian-zhong Chen, Shuang Han, Jiong-jiong Chen, 2013, Yao xue xue bao = Acta pharmaceutica Sinica.

Data Mining a Small Molecule Drug Screening Representative Subset from NIH PubChem

Xiang-Qun Xie, X. Xie, Jian-Zhong Chen, 2008, J. Chem. Inf. Model..

Binding selectivity studies of PKBα using molecular dynamics simulation and free energy calculations

Jian-zhong Chen, Jiong-jiong Chen, Yang Cao, 2013, Journal of Molecular Modeling.

Molecular simulation studies on the binding activity and selectivity of 3-amino-phenyl-5-chloro-pyrimidine-2, 4-diamine derivatives in complexes with kinases c-Met and ALK

You-lu Pan, Jian-zhong Chen, Yan-ling Liu, 2018, Molecular Simulation.

3D-QSAR and docking studies of arylmethylamine-based DPP IV inhibitors

C. Jiang, Jian-zhong Chen, Shuang Han, 2012 .

MD and QM/MM studies on long-chain L-α-hydroxy acid oxidase: substrate binding features and oxidation mechanism.

Haiyan Qian, Jian-zhong Chen, Shuang Han, 2014, The journal of physical chemistry. B.

Design, synthesis and 3D-QSAR study of cytotoxic flavonoid derivatives

Y. Lou, Yongping Yu, Jian-zhong Chen, 2011, Molecular Diversity.

Amidoalkylindoles as Potent and Selective Cannabinoid Type 2 Receptor Agonists with in Vivo Efficacy in a Mouse Model of Multiple Sclerosis.

Y. Duan, Jie Tang, Xin Xie, 2017, Journal of medicinal chemistry.

Development of Quinoline-2,4(1H,3H)-diones as Potent and Selective Ligands of the Cannabinoid Type 2 Receptor.

Xin Xie, Haiyan Qian, Jian-zhong Chen, 2015, Journal of medicinal chemistry.

An overview on Estrogen receptors signaling and its ligands in breast cancer.

Jian-zhong Chen, Muhammad Zafar Irshad Khan, M. Uzair, 2022, European journal of medicinal chemistry.

The nickel-catalyzed C3-acylation of 2H-indazoles with aldehydes.

Jian-zhong Chen, Yan-ling Liu, Youlu Pan, 2019, Organic & biomolecular chemistry.

Computational Simulation Studies on the Binding Selectivity of 1-(1H-Benzimidazol-5-yl)-5-aminopyrazoles in Complexes with FGFR1 and FGFR4

Jian-zhong Chen, Yan-ling Liu, Youlu Pan, 2018, Molecules.

Design, Synthesis, and SAR Studies of Heteroarylpyrimidines and Heteroaryltriazines as CB2R Ligands

Xin Xie, Haiyan Qian, Jian-zhong Chen, 2018, ChemMedChem.

Development of Quinazoline/Pyrimidine-2,4(1H,3H)-diones as Agonists of Cannabinoid Receptor Type 2.

Xin Xie, Haiyan Qian, Jian-zhong Chen, 2017, ACS medicinal chemistry letters.

Computational studies of the regioselectivities of COMT-catalyzed meta-/para-O methylations of luteolin and quercetin.

Zhonghe Chen, Jian-zhong Chen, Yang Cao, 2014, The journal of physical chemistry. B.

Developing pyridazine-3-carboxamides to be CB2 agonists: The design, synthesis, structure-activity relationships and docking studies.

Xin Xie, Haiyan Qian, Jian-zhong Chen, 2017, European journal of medicinal chemistry.

Ni/NHC-catalyzed cross-coupling of methyl sulfinates and amines for direct access to sulfinamides

Jian-zhong Chen, Yan-ling Liu, Youlu Pan, 2019, Tetrahedron Letters.

Beta-caryophyllene is a dietary cannabinoid

Xiang-Qun Xie, Andreas Zimmer, Karl-Heinz Altmann, 2008, Proceedings of the National Academy of Sciences.

Copper(II)-catalysed direct C3-H esterification of indoles assisted by an N,N-bidentate auxiliary moiety.

Jian-zhong Chen, Youlu Pan, Gang-Jian Li, 2021, Organic & biomolecular chemistry.

Direct Acyloxylation of C(sp2)-H and C(sp2)-X (X = Cl, Br) Bonds in Aromatic Amides Using Copper Bromide and 2-(4,5-Dihydro-oxazol-2-yl)-phenylamine.

Jian-zhong Chen, Yan-ling Liu, Youlu Pan, 2019, Organic letters.

Parallel synthesis of novel antitumor agents: 1,2,3-triazoles bearing biologically active sulfonamide moiety and their 3D-QSAR

J. Medina-Franco, M. Giulianotti, Bo Yang, 2011, Molecular Diversity.

Alkylamides from Echinacea Are a New Class of Cannabinomimetics

Xiang-Qun Xie, Bernard Faller, Karl-Heinz Altmann, 2006, Journal of Biological Chemistry.

NMR Structural Comparison of the Cytoplasmic Juxtamembrane Domains of G-protein-coupled CB1 and CB2 Receptors in Membrane Mimetic Dodecylphosphocholine Micelles*

Xiang-Qun Xie, X. Xie, Jian-Zhong Chen, 2005, Journal of Biological Chemistry.

3D structural model of the G‐protein‐coupled cannabinoid CB2 receptor

Xiang-Qun Xie, X. Xie, E. Billings, 2003, Proteins.

Insight into the structural mechanism for PKBα allosteric inhibition by molecular dynamics simulations and free energy calculations.

Jian-zhong Chen, Shuang Han, Yang Cao, 2014, Journal of molecular graphics & modelling.

Data Mining a Small Molecule Drug Screening Representative Subset from NIH PubChem

Xiang-Qun Xie, Jian-zhong Chen, X. Xie, 2008, J. Chem. Inf. Model..

Molecular modeling studies to characterize N-phenylpyrimidin-2-amine selectivity for CDK2 and CDK4 through 3D-QSAR and molecular dynamics simulations.

Tahir Ali Chohan, Jiong-Jiong Chen, Hai-Yan Qian, 2016, Molecular bioSystems.

Design, synthesis, biological evaluation, and comparative docking study of 1,2,4-triazolones as CB1 receptor selective antagonists.

Xin Xie, Jian-zhong Chen, Shuang Han, 2014, European journal of medicinal chemistry.

Preferred conformations of endogenous cannabinoid ligand anandamide.

X. Xie, Xiuwen Han, Jian-zhong Chen, 2005, Life sciences.

GPCR Structure-Based Virtual Screening Approach for CB2 Antagonist Search

Junmei Wang, Xiang-Qun Xie, Jian-zhong Chen, 2007, J. Chem. Inf. Model..

Recent developments in the Medicinal Chemistry and therapeutic potential of anti-cancer Protacs based molecules.

Jian-zhong Chen, Adila Nazli, Youlu Pan, 2022, Current Medicinal Chemistry.

3D-QSAR studies of arylpyrazole antagonists of cannabinoid receptor subtypes CB1 and CB2. A combined NMR and CoMFA approach.

Qian Liu, Xiang-Qun Xie, Junmei Wang, 2006, Journal of medicinal chemistry.

NMR characterization of paclitaxel/poly (styrene-isobutylene-styrene) formulations.

X. Xie, Jian-zhong Chen, S. Ranade, 2005, International journal of pharmaceutics.