L. Dias

发表

Novel isomannide-based peptide mimetics containing a tartaric acid backbone as serine protease inhibitors

A. Tanuri, R. Mohana-Borges, C. R. Rodrigues, 2014, Medicinal Chemistry Research.

In vitro evaluation of antitrypanosomal activity and molecular docking of benzoylthioureas.

M. Bispo, P. Pinge-Filho, S. F. Yamada-Ogatta, 2020, Parasitology international.

Antiplatelet pyrazolopyridines derivatives: pharmacological, biochemical and toxicological characterization

M. G. Albuquerque, A. Lourenço, H. Castro, 2016, Journal of enzyme inhibition and medicinal chemistry.

Trypanocidal activity of new 1,6-diphenyl-1H-pyrazolo[3,4-b]pyridine derivatives: Synthesis, in vitro and in vivo studies.

E. Muri, L. Dias, G. B. Portapilla, 2020, Bioorganic & medicinal chemistry.

Synthesis and analgesic properties of 5-acyl-arylhydrazone 1-H pyrazolo [3,4-b] pyridine derivatives.

E. Barreiro, L. Dias, A. Miranda, 1994, Pharmaceutica acta Helvetiae.

Isosorbide-based peptidomimetics as inhibitors of hepatitis C virus serine protease.

R. Mohana-Borges, T. G. Barros, G. T. Ventura, 2017, Bioorganic & medicinal chemistry letters.

Novel isomannide-based peptide mimetics containing a tartaric acid backbone as serine protease inhibitors

A. Tanuri, R. Mohana-Borges, C. R. Rodrigues, 2014, Medicinal Chemistry Research.

Synthesis, antichagasic in vitro evaluation, cytotoxicity assays, molecular modeling and SAR/QSAR studies of a 2-phenyl-3-(1-phenyl-1H-pyrazol-4-yl)-acrylic acid benzylidene-carbohydrazide series.

M. G. Albuquerque, H. Castro, C. R. Rodrigues, 2009, Bioorganic & medicinal chemistry.

3-Acyltetramic acids as a novel class of inhibitors for human kallikreins 5 and 7.

R. Garrett, S. Pinheiro, E. Muri, 2019, Bioorganic & medicinal chemistry letters.

Synthesis, in vitro evaluation, and SAR studies of a potential antichagasic 1H-pyrazolo[3,4-b]pyridine series.

H. Castro, C. R. Rodrigues, S. Albuquerque, 2007, Bioorganic & Medicinal Chemistry.

Trimethoxy-chalcone derivatives inhibit growth of Leishmania braziliensis: synthesis, biological evaluation, molecular modeling and structure-activity relationship (SAR).

H. Castro, A. Mascarello, T. R. Stumpf, 2011, Bioorganic & medicinal chemistry.

N′-Acetyl-3-methyl-1,6-diphenyl-1H-pyrazolo[3,4-b]pyridine-4-carbohydrazide

L. Dias, J. C. Soares, 2020, Molbank.

Pyrazole Carbohydrazide Derivatives of Pharmaceutical Interest

L. Dias, Raquel R S Salvador, 2012, Pharmaceuticals.

Synthesis and mechanistic evaluation of novel N'-benzylidene-carbohydrazide-1H-pyrazolo[3,4-b]pyridine derivatives as non-anionic antiplatelet agents.

C. Craik, A. Lourenço, H. Castro, 2017, European journal of medicinal chemistry.

Enantioselective bioreduction of ethyl 4,4,4-trihalide-3-oxobutanoate by Kluyveromyces marxianus

L. Dias, F. R. Neto, M. C. K. V. Ramos, 2013 .

Biological evaluation and molecular modeling of peptidomimetic compounds as inhibitors for O-GlcNAc transferase (OGT).

T. G. Barros, A. Todeschini, W. Dias, 2020, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Discovery of a new isomannide-based peptidomimetic synthetized by Ugi multicomponent reaction as human tissue kallikrein 1 inhibitor.

C. R. Rodrigues, T. G. Barros, S. Pinheiro, 2017, Bioorganic & medicinal chemistry letters.

Synthesis, biological evaluation and molecular modeling of pseudo-peptides based statine as inhibitors for human tissue kallikrein 5.

S. Pinheiro, E. Muri, L. Dias, 2016, European journal of medicinal chemistry.

Anti-Trypanosoma cruzi Activity and Molecular Docking Studies of 1Hpyrazolo[ 3, 4-b]pyridine Derivatives

S. Albuquerque, E. Muri, L. Dias, 2020 .

New carbohydrazide derivatives of 1H-pyrazolo[3,4-b]pyridine and trypanocidal activity.

S. Albuquerque, E. Muri, L. Dias, 2016, Anais da Academia Brasileira de Ciencias.

Antiplatelet activity and structure-activity relationship study of Pyrazolopyridine Derivatives as potential series for treating thrombotic diseases.

M. G. Albuquerque, H. Castro, C. R. Rodrigues, 2010, Journal of atherosclerosis and thrombosis.

Sodium Montmorillonite/Amine-Containing Drugs Complexes: New Insights on Intercalated Drugs Arrangement into Layered Carrier Material

H. Castro, C. R. Rodrigues, L. Dias, 2015, PloS one.

Asymmetric bioreduction of β-ketoesters derivatives by Kluyveromyces marxianus: influence of molecular structure on the conversion and enantiomeric excess.

C. R. Rodrigues, L. Dias, M. C. K. V. Ramos, 2017, Anais da Academia Brasileira de Ciencias.

Molecular dynamics simulations of the free and inhibitor-bound cruzain systems in aqueous solvent: insights on the inhibition mechanism in acidic pH

P. Pascutti, M. G. Albuquerque, C. R. Rodrigues, 2016, Journal of biomolecular structure & dynamics.

New Chloroquine Analogues as Antiviral Agents

L. Walker, L. Dias, D. Nanayakkara, 2006 .

Synthesis and analgesic properties of new 4-arylhydrazone 1-H pyrazole [3,4-b] pyridine derivatives.

L. Dias, A. Freitas, M. Gaston, 1996, Pharmaceutica acta Helvetiae.

Inhibition of human monoamine oxidase A and B by 5-phenoxy 8-aminoquinoline analogs.

B. Tekwani, L. Walker, N. Nanayakkara, 2012, Bioorganic & medicinal chemistry letters.

Study of the dynamic behavior of the cruzain enzyme in free and complexed forms with competitive and noncovalent benzimidazole inhibitors

N. Boechat, L. Dias, L. Hoelz, 2022, Journal of biomolecular structure & dynamics.

In silico drug repurposing by combining machine learning classification model and molecular dynamics to identify a potential OGT inhibitor.

E. Muri, L. Dias, Camilo H. da S. Lima, 2023, Journal of biomolecular structure & dynamics.

Antiplatelet pyrazolopyridines derivatives: pharmacological, biochemical and toxicological characterization

M. G. Albuquerque, H. Castro, C. R. Rodrigues, 2016, Journal of enzyme inhibition and medicinal chemistry.