Yucheng Xiao

发表

Identification and characterization of novel proteins from Arizona bark scorpion venom that inhibit Nav1.8, a voltage-gated sodium channel regulator of pain signaling

D. Rokyta, L. Fornelli, T. Cummins, 2021, bioRxiv.

Identification and Characterization of Novel Proteins from Arizona Bark Scorpion Venom That Inhibit Nav1.8, a Voltage-Gated Sodium Channel Regulator of Pain Signaling

D. Rokyta, L. Fornelli, T. Cummins, 2021, Toxins.

Isolation and Characterization of CvIV4: A Pain Inducing α- Scorpion Toxin

H. Zakon, T. Cummins, M. P. Rowe, 2011, PloS one.

Drosotoxin, a selective inhibitor of tetrodotoxin-resistant sodium channels.

Shunyi Zhu, J. Tytgat, S. Peigneur, 2010, Biochemical pharmacology.

Common Molecular Determinants of Tarantula Huwentoxin-IV Inhibition of Na+ Channel Voltage Sensors in Domains II and IV*

James O. Jackson, T. Cummins, Yucheng Xiao, 2011, The Journal of Biological Chemistry.

CRMP2 Protein SUMOylation Modulates NaV1.7 Channel Trafficking*

Sarah M. Wilson, R. Khanna, Yucheng Xiao, 2013, The Journal of Biological Chemistry.

Characterization of Membrane Patch-Ion Channel Probes for Scanning Ion Conductance Microscopy.

L. A. Baker, J. Hou, T. Cummins, 2018, Small.

Tarantula Huwentoxin-IV Inhibits Neuronal Sodium Channels by Binding to Receptor Site 4 and Trapping the Domain II Voltage Sensor in the Closed Configuration*

E. Moczydlowski, T. Cummins, Weiguo Zhu, 2008, Journal of Biological Chemistry.

A-type FHFs mediate resurgent currents through TTX-resistant voltage-gated sodium channels

T. Cummins, Yucheng Xiao, J. W. Theile, 2022, bioRxiv.

Huwentoxin-XVI, an analgesic, highly reversible mammalian N-type calcium channel antagonist from Chinese tarantula Ornithoctonus huwena

Liping Jiang, Weimin Zeng, Yucheng Xiao, 2014, Neuropharmacology.

Jingzhaotoxin-III, a Novel Spider Toxin Inhibiting Activation of Voltage-gated Sodium Channel in Rat Cardiac Myocytes*

Yucheng Xiao, S. Liang, Yuejun Yang, 2004, Journal of Biological Chemistry.

JZTX-IV, a unique acidic sodium channel toxin isolated from the spider Chilobrachys jingzhao.

Yucheng Xiao, S. Liang, Jiang Li, 2008, Toxicon : official journal of the International Society on Toxinology.

Jingzhaotoxin-IX, a novel gating modifier of both sodium and potassium channels from Chinese tarantula Chilobrachys jingzhao

Yucheng Xiao, Meichun Deng, S. Liang, 2009, Neuropharmacology.

Expression and characterization of jingzhaotoxin-34, a novel neurotoxin from the venom of the tarantula Chilobrachys jingzhao

Liping Jiang, Jinjun Chen, Dongyi Zhang, 2009, Peptides.

Native Pyroglutamation of Huwentoxin-IV: A Post-Translational Modification that Increases the Trapping Ability to the Sodium Channel

Jianglin Li, M. Rong, Yucheng Xiao, 2013, PloS one.

Purification and characterization of Hainantoxin-V, a tetrodotoxin-sensitive sodium channel inhibitor from the venom of the spider Selenocosmia hainana.

Yucheng Xiao, S. Liang, 2003, Toxicon : official journal of the International Society on Toxinology.

Structural and Functional Characterization of a Novel Scorpion Toxin that Inhibits NaV1.8 via Interactions With the DI Voltage Sensor and DII Pore Module

V. Yarov-Yarovoy, L. Fornelli, T. Cummins, 2022, Frontiers in Pharmacology.

Synthesis and characterization of huwentoxin-IV, a neurotoxin inhibiting central neuronal sodium channels.

Yucheng Xiao, Meichun Deng, S. Liang, 2008, Toxicon : official journal of the International Society on Toxinology.

Inhibition of neuronal tetrodotoxin-sensitive Na+ channels by two spider toxins: hainantoxin-III and hainantoxin-IV.

Yucheng Xiao, S. Liang, 2003, European journal of pharmacology.

Inhibition of sodium channels in rat dorsal root ganglion neurons by Hainantoxin-IV, a novel spider toxin.

Yucheng Xiao, S. Liang, 2003, Sheng wu hua xue yu sheng wu wu li xue bao Acta biochimica et biophysica Sinica.

Molecular basis of the tarantula toxin jingzhaotoxin‐III (β‐TRTX‐Cj1α) interacting with voltage sensors in sodium channel subtype Nav1.5

Ming Lu, Jinjun Chen, M. Rong, 2011, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Jingzhaotoxin-II, a novel tarantula toxin preferentially targets rat cardiac sodium channel.

Yucheng Xiao, S. Liang, Jiang Li, 2008, Biochemical pharmacology.

Interaction site for the inhibition of tarantula Jingzhaotoxin-XI on voltage-gated potassium channel Kv2.1.

Yingchun He, Yucheng Xiao, Meichun Deng, 2016, Toxicon : official journal of the International Society on Toxinology.

The effects of huwentoxin-I on the voltage-gated sodium channels of rat hippocampal and cockroach dorsal unpaired median neurons

M. Rong, Yucheng Xiao, S. Liang, 2012, Peptides.

Characterization of the excitatory mechanism induced by Jingzhaotoxin-I inhibiting sodium channel inactivation.

Yucheng Xiao, Meichun Deng, S. Liang, 2007, Toxicon : official journal of the International Society on Toxinology.

Inhibition of insect calcium channels by huwentoxin-V, a neurotoxin from Chinese tarantula Ornithoctonus huwena venom.

Yucheng Xiao, Meichun Deng, S. Liang, 2008, European journal of pharmacology.

MOL092338 159..167

K. Blumenthal, T. Cummins, Yucheng Xiao, 2014 .

Increased Resurgent Sodium Currents in Nav1.8 Contribute to Nociceptive Sensory Neuron Hyperexcitability Associated with Peripheral Neuropathies

Jun-Ming Zhang, T. Cummins, W. Xie, 2019, The Journal of Neuroscience.

Enhanced Performance in Electrochromic Devices with High-contrast and Long-term Stability via Synergistic Effect of Cl-/NO3- Dual-anion Electrolyte

H. Qiao, Xiang Qi, Yucheng Xiao, 2022, Journal of Electroanalytical Chemistry.

Substituted N-(Biphenyl-4′-yl)methyl (R)-2-Acetamido-3-methoxypropionamides: Potent Anticonvulsants That Affect Frequency (Use) Dependence and Slow Inactivation of Sodium Channels

Ki Duk Park, Sarah M. Wilson, R. Khanna, 2014, Journal of medicinal chemistry.

Structure-Activity Relationships of Hainantoxin-IV and Structure Determination of Active and Inactive Sodium Channel Blockers*

X. Gu, Yucheng Xiao, S. Liang, 2004, Journal of Biological Chemistry.

Function and solution structure of hainantoxin‐I, a novel insect sodium channel inhibitor from the Chinese bird spider Selenocosmia hainana1

J. Tytgat, F. Bosmans, Yucheng Xiao, 2003, FEBS letters.

Stepwise Differentiation of Retinal Ganglion Cells from Human Pluripotent Stem Cells Enables Analysis of Glaucomatous Neurodegeneration

M. Sarfarazi, T. Cummins, Jason S. Meyer, 2016, Stem cells.

Voltage-Gated Sodium Channel in Grasshopper Mice Defends Against Bark Scorpion Toxin

Harold H Zakon, Yucheng Xiao, H. Zakon, 2013, Science.

Jingzhaotoxin-I, a Novel Spider Neurotoxin Preferentially Inhibiting Cardiac Sodium Channel Inactivation*

J. Tytgat, Yucheng Xiao, S. Liang, 2005, Journal of Biological Chemistry.

The Tarantula Toxins ProTx-II and Huwentoxin-IV Differentially Interact with Human Nav1.7 Voltage Sensors to Inhibit Channel Activation and Inactivation

James O. Jackson, K. Blumenthal, T. Cummins, 2010, Molecular Pharmacology.

Characterization of ion channels on subesophageal ganglion neurons from Chinese tarantula Ornithoctonus huwena: Exploring the myth of the spider insensitive to its venom.

Liping Jiang, Yucheng Xiao, Meichun Deng, 2016, Toxicon : official journal of the International Society on Toxinology.

Human Nav1.6 Channels Generate Larger Resurgent Currents than Human Nav1.1 Channels, but the Navβ4 Peptide Does Not Protect Either Isoform from Use-Dependent Reduction

T. Cummins, Yucheng Xiao, C. Barbosa, 2015, PloS one.

Characterization of Membrane Patch (MP)-Ion Channel Probes (ICPs) for Scanning Ion Conductance Microscopy

L. A. Baker, J. Hou, T. Cummins, 2020 .

Resurgent and Gating Pore Currents Induced by De Novo SCN2A Epilepsy Mutations

S. Cannon, T. Cummins, Fenfen Wu, 2019, eNeuro.

Cardiac sodium channel palmitoylation regulates channel availability and myocyte excitability with implications for arrhythmia generation

A. Hudmon, T. Cummins, Zifan Pei, 2016, Nature Communications.

Alternative splicing of NaV1.7 exon 5 increases the impact of the painful PEPD mutant channel I1461T

James O. Jackson, T. Cummins, Patrick L. Sheets, 2009, Channels.

Gating-Pore Currents Demonstrate Selective and Specific Modulation of Individual Sodium Channel Voltage-Sensors by Biological Toxins

K. Blumenthal, T. Cummins, Yucheng Xiao, 2014, Molecular Pharmacology.

S-Palmitoylation of the sodium channel Nav1.6 regulates its activity and neuronal excitability

T. Cummins, Zifan Pei, Yucheng Xiao, 2020, The Journal of Biological Chemistry.

The human Nav1.5 F1486 deletion associated with long QT syndrome leads to impaired sodium channel inactivation and reduced lidocaine sensitivity

W. Shou, A. Hudmon, Hanying Chen, 2012, The Journal of physiology.

Membrane patches as ion channel probes for scanning ion conductance microscopy.

L. A. Baker, Lushan Zhou, T. Cummins, 2016, Faraday discussions.

Molecular determinants for the tarantula toxin jingzhaotoxin-I interacting with potassium channel Kv2.1.

Yucheng Xiao, Meichun Deng, S. Liang, 2013, Toxicon : official journal of the International Society on Toxinology.

FHF2 isoforms differentially regulate Nav1.6-mediated resurgent sodium currents in dorsal root ganglion neurons

Jun-Ming Zhang, T. Cummins, W. Xie, 2017, Pflügers Archiv - European Journal of Physiology.

by Toggling an Amino Acid in the First S3-S4 Linker Alternative Splicing Modulates Inactivation of Type 1 Voltage-gated Sodium Channels

James O. Jackson, D. Johnston, R. Gray, 2015 .

Solution structure of Jingzhaotoxin-III, a peptide toxin inhibiting both Nav1.5 and Kv2.1 channels.

C. Yuan, Yucheng Xiao, S. Liang, 2007, Toxicon : official journal of the International Society on Toxinology.

Structural Basis for the Modulation of the Neuronal Voltage-Gated Sodium Channel NaV1.6 by Calmodulin

Yucheng Xiao, J. Seetharaman, T. Cummins, 2013, Scientific Reports.

The Diurnal Rhythm of Insulin Receptor Substrate-1 (IRS-1) and Kir4.1 in Diabetes: Implications for a Clock Gene Bmal1

A. Bhatwadekar, T. Cummins, Yucheng Xiao, 2019, Investigative ophthalmology & visual science.

Advanced glycation end (AGE) product modification of laminin downregulates Kir4.1 in retinal Müller cells

A. Bhatwadekar, T. Cummins, Yucheng Xiao, 2018, PloS one.