Steve Stegen

发表

Simultaneous three-dimensional visualization of mineralized and soft skeletal tissues by a novel microCT contrast agent with polyoxometalate structure.

Liesbet Geris, Frank P Luyten, Greet Kerckhofs, 2018, Biomaterials.

HIF-1α Promotes Glutamine-Mediated Redox Homeostasis and Glycogen-Dependent Bioenergetics to Support Postimplantation Bone Cell Survival.

P. Carmeliet, D. Lambrechts, F. Luyten, 2016, Cell metabolism.

Vascular endothelial growth factor and bone–vascular interactions

G. Carmeliet, Steve Stegen, 2020, Principles of Bone Biology.

Single-Cell RNA Sequencing Maps Endothelial Metabolic Plasticity in Pathological Angiogenesis.

Huanming Yang, Jian Wang, L. Bolund, 2020, Cell metabolism.

Breast cancer cells rely on environmental pyruvate to shape the metastatic niche

C. Verfaillie, G. Carmeliet, E. Verbeken, 2019, Nature.

Lipid availability determines skeletal progenitor cell fate via SOX9

P. Carmeliet, F. Maes, Dariusz Przybylski, 2020, Nature.

The vasculature: a vessel for bone metastasis.

G. Carmeliet, N. van Gastel, Steve Stegen, 2015, BoneKEy reports.

The skeletal vascular system - Breathing life into bone tissue.

G. Carmeliet, Steve Stegen, 2017, Bone.

The Combination of the CDK4/6 Inhibitor, Palbociclib, With the Vitamin D3 Analog, Inecalcitol, Has Potent In Vitro and In Vivo Anticancer Effects in Hormone-Sensitive Breast Cancer, But Has a More Limited Effect in Triple-Negative Breast Cancer

H. Wildiers, L. Verlinden, A. Verstuyf, 2022, Frontiers in Endocrinology.

Osteocytic oxygen sensing controls bone mass through epigenetic regulation of sclerostin

P. Carmeliet, B. Thienpont, G. Carmeliet, 2018, Nature Communications.

Amino acid metabolism in skeletal cells

G. Carmeliet, Steve Stegen, Claire-Sophie Devignes, 2022, Bone reports.

Skeletal progenitors preserve proliferation and self-renewal upon inhibition of mitochondrial respiration by rerouting the TCA cycle

P. Carmeliet, B. Thienpont, G. Carmeliet, 2022, Cell reports.

Glutamine Metabolism in Osteoprogenitors Is Required for Bone Mass Accrual and PTH‐Induced Bone Anabolism in Male Mice

P. Carmeliet, G. Carmeliet, S. Torrekens, 2020, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Isolation and in vitro characterization of murine young-adult long bone skeletal progenitors

G. Carmeliet, Steve Stegen, I. Stockmans, 2022, Frontiers in Endocrinology.

Biological Activity of CXCL8 Forms Generated by Alternative Cleavage of the Signal Peptide or by Aminopeptidase-Mediated Truncation

P. Proost, J. Van Damme, Steve Stegen, 2011, PloS one.

Expansion of Murine Periosteal Progenitor Cells with Fibroblast Growth Factor 2 Reveals an Intrinsic Endochondral Ossification Program Mediated by Bone Morphogenetic Protein 2

Jan Schrooten, Geert Carmeliet, Daniel Graf, 2014, Stem cells.

Hypoxia, hypoxia-inducible transcription factors and oxygen-sensing prolyl hydroxylases in bone development and homeostasis.

G. Carmeliet, Steve Stegen, 2019, Current opinion in nephrology and hypertension.

Inhibition of the Oxygen Sensor PHD2 Enhances Tissue‐Engineered Endochondral Bone Formation

Geert Carmeliet, G. Carmeliet, N. van Gastel, 2018, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

HIF-1α metabolically controls collagen synthesis and modification in chondrocytes

P. Carmeliet, D. Eyre, G. Carmeliet, 2019, Nature.

Bringing new life to damaged bone: the importance of angiogenesis in bone repair and regeneration.

Geert Carmeliet, G. Carmeliet, N. van Gastel, 2015, Bone.

Highly proliferative primitive fetal liver hematopoietic stem cells are fueled by oxidative metabolic pathways.

P. Carmeliet, A. Pascual-Montano, C. Verfaillie, 2015, Stem cell research.

De novo serine synthesis regulates chondrocyte proliferation during bone development and repair

P. Carmeliet, G. Carmeliet, Steve Stegen, 2022, Bone Research.

HIF-1α metabolically controls collagen synthesis and modification in chondrocytes

P. Carmeliet, D. Eyre, G. Carmeliet, 2019, Nature.

Breast cancer cells rely on environmental pyruvate to shape the metastatic niche

C. Verfaillie, G. Carmeliet, E. Verbeken, 2019, Nature.

Glutamine Metabolism Controls Chondrocyte Identity and Function.

P. Carmeliet, B. Thienpont, G. Carmeliet, 2020, Developmental cell.

Osteocyte Egln1/Phd2 links oxygen sensing and biomineralization via FGF23

W. R. Thompson, K. White, Guanglong Jiang, 2023, Bone Research.

Adequate hypoxia inducible factor 1α signaling is indispensable for bone regeneration.

P. Carmeliet, G. Carmeliet, J. Goveia, 2016, Bone.

Lipid availability determines fate of skeletal progenitor cells via SOX9

P. Carmeliet, Dariusz Przybylski, D. Lambrechts, 2020, Nature.

Osteocytic oxygen sensing controls bone mass through epigenetic regulation of sclerostin

P. Carmeliet, B. Thienpont, G. Carmeliet, 2018, Nature Communications.

FGF2 primes periosteal cells for endochondral ossification via maintenance of skeletal precursors and modulation of BMP signaling

J. Schrooten, F. Luyten, G. Carmeliet, 2013 .

Nestin-GFP transgene labels skeletal progenitors in the periosteum.

G. Carmeliet, N. van Gastel, Steve Stegen, 2020, Bone.

Highly proliferative primitive fetal liver hematopoietic stem cells are fueled by oxidative metabolic pathways.

P. Carmeliet, A. Pascual-Montano, C. Verfaillie, 2015, Stem cell research.

Expansion of Murine Periosteal Progenitor Cells with Fibroblast Growth Factor 2 Reveals an Intrinsic Endochondral Ossification Program Mediated by Bone Morphogenetic Protein 2

J. Schrooten, F. Luyten, G. Carmeliet, 2014, Stem cells.

Metabolic regulation of skeletal cell fate and function.

G. Carmeliet, Steve Stegen, 2024, Nature reviews. Endocrinology.

Simultaneous three-dimensional visualization of mineralized and soft skeletal tissues by a novel microCT contrast agent with polyoxometalate structure.

G. Kerckhofs, F. Luyten, L. Geris, 2018, Biomaterials.