Z. Cao

发表

Taking Quinazoline as a General Support‐Nog to Design Potent and Selective Kinase Inhibitors: Application to FMS‐like Tyrosine Kinase 3

Li Yang, Yu-Quan Wei, Xiao-Yu Qing, 2010, ChemMedChem.

SKLB610: A Novel Potential Inhibitor of Vascular Endothelial Growth Factor Receptor Tyrosine Kinases Inhibits Angiogenesis and Tumor Growth in Vivo

Shi-Dong Luo, Yuquan Wei, Sheng-yong Yang, 2011, Cellular Physiology and Biochemistry.

Preclinical pharmacodynamic evaluation of drug candidate SKLB-178 in the treatment of non-small cell lung cancer

Yiguo Hu, Xin Chen, L. Zhong, 2017, Oncotarget.

Discovery of a novel and potent inhibitor with differential species-specific effects against NLRP3 and AIM2 inflammasome-dependent pyroptosis.

Shanshan Zhang, Shengyong Yang, J. Nan, 2022, European journal of medicinal chemistry.

SKLB1028, a novel oral multikinase inhibitor of EGFR, FLT3 and Abl, displays exceptional activity in models of FLT3-driven AML and considerable potency in models of CML harboring Abl mutants

L. Zhong, R. Zheng, Z. Cao, 2012, Leukemia.

Discovery of the novel potent and selective FLT3 inhibitor 1-{5-[7-(3- morpholinopropoxy)quinazolin-4-ylthio]-[1,3,4]thiadiazol-2-yl}-3-p-tolylurea and its anti-acute myeloid leukemia (AML) activities in vitro and in vivo.

Yong Xu, Shan Feng, L. Zhong, 2012, Journal of medicinal chemistry.

A Specific Pharmacophore Model of Aurora B Kinase Inhibitors and Virtual Screening Studies Based on it

Shi-Dong Luo, Lin-Li Li, Yuquan Wei, 2009, Chemical biology & drug design.

Pharmacophore Modelling and Virtual Screening for Identification of New Aurora‐A Kinase Inhibitors

Ming-Li Xiang, Yu-Quan Wei, Ying-Lan Zhao, 2008, Chemical biology & drug design.

Identification of a small molecule that downregulates MITF expression and mediates antimelanoma activity in vitro

J. Shang, Xin Chen, Sheng-yong Yang, 2016, Melanoma research.

SKLB1002, a Novel Potent Inhibitor of VEGF Receptor 2 Signaling, Inhibits Angiogenesis and Tumor Growth In Vivo

Yuquan Wei, Xia Zhao, Wei Wang, 2011, Clinical Cancer Research.

Cancer Therapy : Preclinical SKLB 1002 , a Novel Potent Inhibitor of VEGF Receptor 2 Signaling , Inhibits Angiogenesis and Tumor Growth In Vivo

Yuquan Wei, Xia Zhao, Wei Wang, 2011 .

SKLB1206, a Novel Orally Available Multikinase Inhibitor Targeting EGFR Activating and T790M Mutants, ErbB2, ErbB4, and VEGFR2, Displays Potent Antitumor Activity Both In Vitro and In Vivo

Yong Xu, Yang Yu, Xin Chen, 2012, Molecular Cancer Therapeutics.

Preclinical Development SKLB 1206 , a Novel Orally Available Multikinase Inhibitor Targeting EGFR Activating and T 790 M Mutants , ErbB 2 , ErbB 4 , and VEGFR 2 , Displays Potent Antitumor Activity Both In Vitro and In Vivo

Shan Feng, Shi-Dong Luo, You-Li Pan, 2012 .

Barbigerone, a Natural Isoflavone, Induces Apoptosis in Murine Lung-Cancer Cells via the Mitochondrial Apoptotic Pathway

Xia Zhao, Yuquan Wei, A. Peng, 2009, Cellular Physiology and Biochemistry.

Pharmacophore modeling and virtual screening for designing potential PLK1 inhibitors.

Shi-Dong Luo, Lin-Li Li, Yuquan Wei, 2008, Bioorganic & medicinal chemistry letters.

Discovery of Novel Pim-1 Kinase Inhibitors by a Hierarchical Multistage Virtual Screening Approach Based on SVM Model, Pharmacophore, and Molecular Docking

Xin Chen, Lin-Li Li, Sheng-Yong Yang, 2011, J. Chem. Inf. Model..

Design, Synthesis, and Preliminary Antitumor Activity Evaluation of Novel Alkaloid Derivatives

Z. Cao, Li Guo, Li-Jiao Wang, 2020 .

Efficient inhibition of lung cancer in murine model by plasmid-encoding VEGF short hairpin RNA in combination with low-dose DDP

Yuquan Wei, Xia Zhao, N. Zhang, 2010, Journal of experimental & clinical cancer research : CR.

Barbigerone, a Natural Isoflavone, Induces Apoptosis in Murine Lung-Cancer Cells via the Mitochondrial Apoptotic Pathway

Xia Zhao, Yuquan Wei, A. Peng, 2009, Cellular Physiology and Biochemistry.