Wenyuan Qian

发表

One-pot synthesis of 3-triazolyl-quinolin-2-(1H)-ones via sequential Ugi-“click”-Knoevenagel condensations

Peng Yu, Wenyuan Qian, Dahai Wang, 2018 .

Copper-catalyzed domino cycloaddition/C-N coupling/cyclization/(C-H arylation): an efficient three-component synthesis of nitrogen polyheterocycles.

Hao Wang, Wenyuan Qian, Jennifer R. Allen, 2013, Angewandte Chemie.

One-pot synthesis of 3-triazolyl-2-iminochromenes via a catalytic three component cascade reaction.

Wenyuan Qian, Jennifer R. Allen, A. Amegadzie, 2013, Organic letters.

One-pot synthesis of [1,2,3]triazole-fused pyrazinopyridazindione tricycles by a ‘click and activate’ approach

Wenyuan Qian, Jennifer R. Allen, A. Amegadzie, 2012 .

Discovery of 2-methylpyridine-based biaryl amides as γ-secretase modulators for the treatment of Alzheimer's disease.

Shannon Rumfelt, N. Chen, S. Hitchcock, 2013, Bioorganic & medicinal chemistry letters.

TRIPLET-STATE PROPERTIES AND SINGLET OXYGEN GENERATION IN A HOMOLOGOUS SERIES OF FUNCTIONALIZED FULLERENE DERIVATIVES

Y. Rubin, R. Bernstein, C. Foote, 1999 .

Pressure-tuning vibrational spectroscopic study of (η5-C5H5)Co(C64H4) Can endohedral fullerenes be formed under pressure?

Y. Rubin, I. Butler, Wenyuan Qian, 1998 .

Convergent, regioselective synthesis of tetrakisfulleroids from C(60).

Y. Rubin, Wenyuan Qian, 2002, The Journal of organic chemistry.

Development of 2-aminooxazoline 3-azaxanthenes as orally efficacious β-secretase inhibitors for the potential treatment of Alzheimer's disease.

S. Hitchcock, A. Cheng, Yuan Cheng, 2015, Bioorganic & medicinal chemistry letters.

Regioselective synthesis of multiply halogenated azaxanthones

James Brown, Wenyuan Qian, J. Chen, 2014 .

Decarboxylative Benzylation of Aryl and Alkenyl Boronic Esters.

Wenyuan Qian, Patrick J. Moon, R. Lundgren, 2018, Angewandte Chemie.

Expanding the limit of Pd-catalyzed decarboxylative benzylations.

D. Kong, Wenyuan Qian, Patrick J. Moon, 2018, Chemical communications.

Synthesis and evaluation of hydrazinyl-containing pyrrolo[2,3-d]pyri midine series as potent, selective and oral JAK1 inhibitors for the treatment of rheumatoid arthritis.

Shuhui Chen, Wenyuan Qian, Weiwei Mao, 2022, Bioorganic & medicinal chemistry letters.

Discovery of dehydro-oxopiperazine acetamides as novel bradykinin B1 receptor antagonists with enhanced in vitro potency.

L. Arik, R. Hungate, Jiawang Zhu, 2012, Bioorganic & medicinal chemistry letters.

Accelerating effect of triazolyl and related heteroaryl substituents on SNAr reactions: evidence of hydrogen-bond stabilized transition states.

M. Bartberger, Wenyuan Qian, Hao Wang, 2015, Journal of the American Chemical Society.

Discovery of dihydroquinoxalinone acetamides containing bicyclic amines as potent Bradykinin B1 receptor antagonists.

S. Hitchcock, L. Arik, V. Viswanadhan, 2008, Bioorganic & medicinal chemistry letters.

Total synthesis and structural elucidation of azaspiracid-1. Construction of key building blocks for originally proposed structure.

K. Nicolaou, F. Bernal, M. O. Frederick, 2006, Journal of the American Chemical Society.

Total synthesis of the proposed azaspiracid-1 structure, part 1: construction of the enantiomerically pure C1-C20, C21-C27, and C28-C40 fragments.

K. Nicolaou, S. Vyskocil, F. Bernal, 2003, Angewandte Chemie.

Total synthesis of the proposed azaspiracid-1 structure, part 2: coupling of the C1-C20, C21-C27, and C28-C40 fragments and completion of the synthesis.

K. Nicolaou, S. Vyskocil, T. Ling, 2003, Angewandte Chemie.

Synthesis of the ABCD Ring System of Azaspiracid.

K. Nicolaou, F. Bernal, P. Pihko, 2001 .

Decarboxylative Benzylation of sp2-Organoboron Reagents.

Wenyuan Qian, Patrick J. Moon, R. Lundgren, 2018 .

Synthesis of stable derivatives of c(62): the first nonclassical fullerene incorporating a four-membered ring.

Michael Sander, Yves Rubin, Y. Rubin, 2003, Journal of the American Chemical Society.

Aryl sulfones as novel bradykinin B1 receptor antagonists for treatment of chronic pain.

L. Arik, R. Hungate, G. Biddlecome, 2008, Bioorganic & medicinal chemistry letters.

Aryl sulfonamides containing tetralin allylic amines as potent and selective bradykinin B1 receptor antagonists.

L. Arik, R. Hungate, G. Biddlecome, 2010, Bioorganic & medicinal chemistry letters.

The development of a structurally distinct series of BACE1 inhibitors via the (Z)-fluoro-olefin amide bioisosteric replacement.

N. Chen, D. Whittington, M. Bartberger, 2020, Bioorganic & medicinal chemistry letters.

An Orally Available BACE1 Inhibitor That Affords Robust CNS Aβ Reduction without Cardiovascular Liabilities.

Xiao Mei Zheng, R. Wahl, S. Hitchcock, 2015, ACS medicinal chemistry letters.

A Parallel Library of all Seven A2+B2+C2Th Regioisomeric Hexakisadducts of Fullerene C60: Inspiration from Werner's Octahedral Stereoisomerism

Yves Rubin, Y. Rubin, Wenyuan Qian, 2000 .

C62, a Non-Classical Fullerene Incorporating a Four-Membered Ring

Charles L. Wilkins, Kendall N. Houk, Yves Rubin, 2000 .

A "click and activate" approach in one-pot synthesis of a triazolyl-pyridazinone library.

Wenyuan Qian, Jennifer R. Allen, D. Winternheimer, 2011, Organic Letters.

A “Click and Activate” Approach in One-Pot Synthesis of a Triazolyl-Pyridazinone Library.

Wenyuan Qian, Jennifer R. Allen, D. Winternheimer, 2011 .