David K. Johnson

发表

Pocket optimization and its application to identify small-molecule inhibitors of protein-protein interactions

David K. Johnson, 2016 .

DARC: Mapping Surface Topography by Ray-Casting for Effective Virtual Screening at Protein Interaction Sites.

Anuradha Roy, Jeffrey Aubé, Ragul Gowthaman, 2016, Journal of medicinal chemistry.

Fatty Acid Composition by Total Acyl Lipid Collision-Induced Dissociation Time-of-Flight (TAL-CID-TOF) Mass Spectrometry.

R. Welti, T. Williams, David K. Johnson, 2021, Methods in molecular biology.

Modulating β-arrestin 2 recruitment at the δ- and μ-opioid receptors using peptidomimetic ligands.

David K. Johnson, Ryan A. Altman, Yazan J Meqbil, 2021, RSC medicinal chemistry.

Design, synthesis and evaluation of inhibitors of the SARS-CoV-2 nsp3 macrodomain

Anthony R. Fehr, A. Leung, A. Walker, 2022, Bioorganic & Medicinal Chemistry.

Discovery of compounds that inhibit SARS-CoV-2 Mac1-ADP-ribose binding by high-throughput screening

Peter R. McDonald, Anthony R. Fehr, A. Leung, 2022, Antiviral Research.

Structural and ligand binding analyses of the periplasmic sensor domain of RsbU in Chlamydia trachomatis support a role in TCA cycle regulation

Yang Zhang, K. Battaile, Zoe E. Dimond, 2020, Molecular microbiology.

Diflunisal Derivatives as Modulators of ACMS Decarboxylase Targeting the Tryptophan-Kynurenine Pathway.

David K. Johnson, Ryan A. Altman, Yu Yang, 2020, Journal of medicinal chemistry.

The Structures of SctK and SctD from Pseudomonas aeruginosa Reveal the Interface of the Type III Secretion System Basal Body and Sorting Platform

W. Picking, K. Battaile, M. Muthuramalingam, 2020, bioRxiv.

Modulating β Arrestin-2 Recruitment at the δ- and μ-Opioid Receptors

David K. Johnson, Ryan A. Altman, R. V. van Rijn, 2020 .

Potent Protease Inhibitors of Highly Pathogenic Lagoviruses: Rabbit Hemorrhagic Disease Virus and European Brown Hare Syndrome Virus

W. Groutas, Yunjeong Kim, Kyeong-Ok Chang, 2022, Microbiology spectrum.

The Legionella pneumophila metaeffector Lpg2505 (SusF) regulates SidI-mediated translation inhibition and GDP-dependent glycosyltransferase activity

B. Geisbrecht, Stephanie R. Shames, David K. Johnson, 2019, bioRxiv.

LipidomeDB Data Calculation Environment Has Been Updated to Process Direct-Infusion Multiple Reaction Monitoring Data.

R. Welti, David K. Johnson, Carl Fruehan, 2018, Lipids.

DNAJA1- and conformational mutant p53-dependent inhibition of cancer cell migration by a novel compound identified through a virtual screen

T. Iwakuma, A. Parrales, A. Kaida, 2022, Cell Death Discovery.

Rationally designed inhibitors of the Musashi protein-RNA interaction by hotspot mimicry

Yusuf O. Adeshina, Sven A. Miller, J. Karanicolas, 2023, bioRxiv.

The Discovery of Conformationally Constrained Bicyclic Peptidomimetics as Potent Hepatitis C NS5A Inhibitors

W. Kazmierski, David K. Johnson, Nagaraju Miriyala, 2021, ACS medicinal chemistry letters.

Influence of ligand geometry on cholinesterase enzyme - A comparison of 1-isoindolinone based structural analog with Donepezil.

W. Suo, Mukut Sharma, S. Upadhyay, 2022, Journal of molecular structure.

Rationally designed inhibitors of the Musashi protein-RNA interaction by hotspot mimicry

Yusuf O. Adeshina, Sven A. Miller, J. Karanicolas, 2023, bioRxiv : the preprint server for biology.

Potent protease inhibitors of deadly lagoviruses: rabbit hemorrhagic disease virus and European brown hare syndrome virus

W. Groutas, Yunjeong Kim, Kyeong-Ok Chang, 2022, bioRxiv.

Computational Screening and Design for Compounds that Disrupt Protein-protein Interactions.

John Karanicolas, David K Johnson, J. Karanicolas, 2017, Current topics in medicinal chemistry.

A Borrelia burgdorferi LptD Homolog Facilitates Flipping of Surface Lipoproteins Through the Spirochetal Outer Membrane

L. Florens, S. Swanson, W. Zückert, 2022, bioRxiv.

Macromolecular modeling and design in Rosetta: recent methods and frameworks

Brian D. Weitzner, Lars Malmström, Karen R. Khar, 2020, Nature Methods.

The fungal natural product azaphilone-9 binds to HuR and inhibits HuR-RNA interaction in vitro

J. Karanicolas, K. Kaur, Lan Lan, 2017, PloS one.

The SARS-CoV-2 conserved macrodomain is a mono-ADP-ribosylhydrolase

Anthony R. Fehr, J. Gagné, G. Poirier, 2020, bioRxiv.

Costameric integrin and sarcoglycan protein levels are altered in a Drosophila model for Limb-girdle muscular dystrophy type 2H

M. Zółkiewski, A. R. Re Cecconi, R. Piccirillo, 2020, Molecular biology of the cell.

Selectivity by Small-Molecule Inhibitors of Protein Interactions Can Be Driven by Protein Surface Fluctuations

David K. Johnson, John Karanicolas, J. Karanicolas, 2015, PLoS Comput. Biol..

Druggable Protein Interaction Sites Are More Predisposed to Surface Pocket Formation than the Rest of the Protein Surface

David K. Johnson, John Karanicolas, J. Karanicolas, 2013, PLoS Comput. Biol..

Ultra-High-Throughput Structure-Based Virtual Screening for Small-Molecule Inhibitors of Protein-Protein Interactions

David K. Johnson, John Karanicolas, J. Karanicolas, 2016, J. Chem. Inf. Model..

Simple and Rapid High-Throughput Assay to Identify HSV-1 ICP0 Transactivation Inhibitors

David K. Johnson, Anuradha Roy, D. Davido, 2021, bioRxiv.

The Legionella pneumophila Metaeffector Lpg2505 (MesI) Regulates SidI-Mediated Translation Inhibition and Novel Glycosyl Hydrolase Activity

B. Geisbrecht, Stephanie R. Shames, David K. Johnson, 2020, Infection and Immunity.

Design, synthesis and evaluation of inhibitors of the SARS-CoV-2 nsp3 macrodomain

Anthony R. Fehr, A. Leung, A. Walker, 2022, bioRxiv.

The Structures of SctK and SctD from Pseudomonas aeruginosa Reveal the Interface of the Type III Secretion System Basal Body and Sorting Platform.

W. Picking, K. Battaile, M. Muthuramalingam, 2020, Journal of molecular biology.

The SARS-CoV-2 Conserved Macrodomain Is a Mono-ADP-Ribosylhydrolase

Anthony R. Fehr, J. Gagné, G. Poirier, 2020, Journal of Virology.

Structural and Biological Evaluations of a Non-Nucleoside STING Agonist Specific for Human STINGA230 Variants

Y. Li, Pingwei Li, Jingxin Wang, 2023, bioRxiv.

A Borrelia burgdorferi LptD homolog is required for flipping of surface lipoproteins through the spirochetal outer membrane

L. Florens, S. Swanson, W. Zückert, 2023, Molecular microbiology.

Identification of a novel transport system in Borrelia burgdorferi that links the inner and outer membranes

A. MacKerell, Melisha R. Kenedy, D. Akins, 2023, Pathogens and disease.

Rationally designed inhibitors of the Musashi protein-RNA interaction by hotspot mimicry

Yusuf O. Adeshina, J. Karanicolas, Y. Boumber, 2023, Research square.

Unique Mutations in the Murine Hepatitis Virus Macrodomain Differentially Attenuate Virus Replication, Indicating Multiple Roles for the Macrodomain in Coronavirus Replication

Anthony R. Fehr, David K. Johnson, C. M. Kerr, 2021, Journal of virology.

An MHV macrodomain mutant predicted to lack ADP-ribose binding activity is severely attenuated, indicating multiple roles for the macrodomain in coronavirus replication

Anthony R. Fehr, David K. Johnson, C. M. Kerr, 2021, bioRxiv.

Structural and Biological Evaluations of a Non-Nucleoside STING Agonist Specific for Human STINGA230 Variants

Y. Li, Pingwei Li, Jingxin Wang, 2023, bioRxiv.

Discovery of compounds that inhibit SARS-CoV-2 Mac1-ADP-ribose binding by high-throughput screening

Anthony R. Fehr, A. Leung, D. Ferraris, 2022, bioRxiv.

Ultra-High-Throughput Structure-Based Virtual Screening for Small-Molecule Inhibitors of Protein-Protein Interactions

J. Karanicolas, David K. Johnson, 2016, J. Chem. Inf. Model..