J. Clampit

发表

Discovery and characterization of non-ATP site inhibitors of the mitogen activated protein (MAP) kinases.

Hua Tang, Bo Liu, Gang Liu, 2011, ACS chemical biology.

Aminopyridine-based c-Jun N-terminal kinase inhibitors with cellular activity and minimal cross-kinase activity.

Chaohong Sun, E. Olejniczak, Eric F. Johnson, 2006, Journal of medicinal chemistry.

Discovery of potent, highly selective, and orally bioavailable pyridine carboxamide c-Jun NH2-terminal kinase inhibitors.

Eric F. Johnson, C. Abad-Zapatero, H. Sham, 2006, Journal of Medicinal Chemistry.

Aminopyridine carboxamides as c-Jun N-terminal kinase inhibitors: targeting the gatekeeper residue and beyond.

H. Sham, R. Gum, D. Haasch, 2006, Bioorganic & medicinal chemistry letters.

Reduction of protein-tyrosine phosphatase-1B increases insulin signaling in FAO hepatoma cells.

C. Rondinone, J. Trevillyan, Harriet T. Smith, 2003, Biochemical and biophysical research communications.

PKCθ is a key player in the development of insulin resistance

C. Rondinone, T. Pederson, D. Haasch, 2006 .

Protein tyrosine phosphatase 1B reduction regulates adiposity and expression of genes involved in lipogenesis.

J. Waring, R. Ulrich, B. Monia, 2002, Diabetes.

Protein Tyrosine Phosphatase 1B Reduction Regulates Adiposity and Expression of Genes Involved in

J. Waring, R. Ulrich, B. Monia, 2002 .

PKCtheta is a key player in the development of insulin resistance.

C. Rondinone, T. Pederson, D. Haasch, 2006, Biochemical and biophysical research communications.

In Vitro Enzymatic Assays of Protein Tyrosine Phosphatase 1B

J. Trevillyan, T. Lubben, M. Stashko, 2001, Current protocols in pharmacology.

Synthesis and SAR of 1,9-dihydro-9-hydroxypyrazolo[3,4-b]quinolin-4-ones as novel, selective c-Jun N-terminal kinase inhibitors.

C. Abad-Zapatero, H. Sham, R. Gum, 2006, Bioorganic & medicinal chemistry letters.

PTP1B antisense oligonucleotide lowers PTP1B protein, normalizes blood glucose, and improves insulin sensitivity in diabetic mice

J. Waring, R. Ulrich, S. Crosby, 2002, Proceedings of the National Academy of Sciences of the United States of America.

PTP1B antisense-treated mice show regulation of genes involved in lipogenesis in liver and fat

J. Waring, R. Ulrich, C. Rondinone, 2003, Molecular and Cellular Endocrinology.

Discovery of a new class of 4-anilinopyrimidines as potent c-Jun N-terminal kinase inhibitors: Synthesis and SAR studies.

C. Abad-Zapatero, H. Sham, C. Rondinone, 2007, Bioorganic & medicinal chemistry letters.

Developmental switch from prolonged insulin action to increased insulin sensitivity in protein tyrosine phosphatase 1B-deficient hepatocytes.

M. Benito, Á. Valverde, Á. González-Rodríguez, 2007, Endocrinology.

Reduction of protein tyrosine phosphatase 1B increases insulin-dependent signaling in ob/ob mice.

R. Ulrich, C. Rondinone, R. Gum, 2003, Diabetes.

Reduction of PTP1B induces differential expression of PI3-kinase (p85α) isoforms

C. Rondinone, R. Gum, J. Trevillyan, 2004 .

Putting Thought to Paper: A μARCS Protease Screen

U. Warrior, D. Burns, D. Groebe, 2003 .