Jonathan M. Moore

发表

Application of NMR SHAPES screening to an RNA target.

Jeffrey W. Peng, Victoria A Feher, J. Williamson, 2003, Journal of the American Chemical Society.

Theory and applications of NMR-based screening in pharmaceutical research.

Jeffrey W. Peng, Christopher A Lepre, Jonathan M Moore, 2004, Chemical reviews.

Solution structure of the major binding protein for the immunosuppressant FK506

M. Fitzgibbon, D. Peattie, John A. Thomson, 1991, Nature.

Theory and Applications of NMR‐Based Screening in Pharmaceutical Research

Jeffrey W. Peng, Christopher A. Lepre, C. Lepre, 2004 .

NMR experiments for lead generation in drug discovery

Jeffrey W. Peng, N. Abdul-Manan, Jonathan M. Moore, 2004 .

NMR SHAPES Screening

Christopher A. Lepre, Jonathan M. Moore, 2008 .

Combinatorial triple-selective labeling as a tool to assist membrane protein backbone resonance assignment

V. Dötsch, F. Löhr, F. Bernhard, 2012, Journal of biomolecular NMR.

Crystal structure of the ectodomain complex of the CGRP receptor, a class-B GPCR, reveals the site of drug antagonism.

C. Koth, L. Swenson, E. ter Haar, 2010, Structure.

Dynamic NMR studies of ligand‐receptor interactions: Design and analysis of a rapidly exchanging complex of FKBP‐12/FK506 with a 24 kDa calcineurin fragment

M. Su, J. Peng, J. Thomson, 1996, Protein science : a publication of the Protein Society.

Identification of potent CNS-penetrant thiazolidinones as novel CGRP receptor antagonists.

Sabine Hadida, C. Decker, A. Termin, 2014, Bioorganic & medicinal chemistry letters.

From nanodiscs to isotropic bicelles: a procedure for solution NMR studies of detergent sensitive integral membrane proteins

F. Löhr, E. Perozo, F. Bernhard, 2016 .

Drug Design: NMR in fragment-based drug discovery

P. Connolly, C. Lepre, Jonathan M. Moore, 2010 .

Refolding and characterization of a soluble ectodomain complex of the calcitonin gene-related peptide receptor.

C. Koth, J. Lippke, P. Connolly, 2010, Biochemistry.

Nucleotide-binding Domains of Cystic Fibrosis Transmembrane Conductance Regulator, an ABC Transporter, Catalyze Adenylate Kinase Activity but Not ATP Hydrolysis*

J. Fulghum, J. Lippke, C. Faerman, 2006, Journal of Biological Chemistry.

Combinatorial triple-selective labeling as a tool to assist membrane protein backbone resonance assignment

V. Dötsch, F. Löhr, F. Bernhard, 2012, Journal of Biomolecular NMR.

Nitrogen-15 NMR relaxation studies of the FK506 binding protein: Backbone dynamics of the uncomplexed receptor

J. Fulghum, S. P. Chambers, Jyawei Cheng, 1993 .

ABC transporters: human disease and pharmacotherapeutic potential.

A. Garfield, E. Bell, Alastair S. Garfield, 2022, Trends in molecular medicine.

Microdrop screening: A rapid method to optimize solvent conditions for NMR spectroscopy of proteins

J M Moore, C A Lepre, C. Lepre, 1998, Journal of biomolecular NMR.

Solution structure of FK506 bound to FKBP‐12

J. Thomson, C. Lepre, Jonathan M. Moore, 1992, FEBS letters.

Practical applications of time-averaged restrained molecular dynamics to ligand-receptor systems: FK506 bound to the Q50R,A95H,K98I triple mutant of FKBP-13

D. Pearlman, J. Moore, D. Livingston, 1996, Journal of biomolecular NMR.

Dynamics of a receptor-bound ligand by heteronuclear NMR: FK506 bound to FKBP-12

Jyawei Cheng, C. Lepre, Jonathan M. Moore, 1993 .

Leveraging structural approaches: applications of NMR-based screening and X-ray crystallography for inhibitor design.

Jeffrey W. Peng, Xiaoling Xie, M. Jacobs, 2004, Journal of synchrotron radiation.

Fragment-Based NMR Screening in Lead Discovery

C. Lepre, Jonathan M. Moore, 2007 .

Time-shared experiments for efficient assignment of triple-selectively labeled proteins.

V. Dötsch, F. Löhr, P. Connolly, 2014, Journal of magnetic resonance.

Applications of SHAPES screening in drug discovery.

Jeffrey W. Peng, Xiaoling Xie, J. Pocas, 2002, Combinatorial chemistry & high throughput screening.

The SHAPES strategy: an NMR-based approach for lead generation in drug discovery.

Ajay, G. Bemis, M. Murcko, 1999, Chemistry & biology.

NMR techniques for characterization of ligand binding: utility for lead generation and optimization in drug discovery.

J. Moore, Jonathan M. Moore, 1999, Biopolymers.

Crystal structure of the ectodomain complex of the CGRP receptor, a class-B GPCR, reveals the site of drug antagonism.

C. Koth, L. Swenson, E. ter Haar, 2010, Structure.

From Nanodiscs to Isotropic Bicelles: A Procedure for Solution Nuclear Magnetic Resonance Studies of Detergent-Sensitive Integral Membrane Proteins.

V. Dötsch, F. Löhr, E. Perozo, 2016, Structure.

Nuclear magnetic resonance-based approaches for lead generation in drug discovery.

J. Peng, J. Moore, N. Abdul-Manan, 2001, Methods in enzymology.