D. Perlow

发表

A potent cyclic hexapeptide analogue of somatostatin

Ruth F. Nutt, Roger M. Freidinger, Ralph Hirschmann, 1981, Nature.

Protected lactam-bridged dipeptides for use as conformational constraints in peptides

Roger M. Freidinger, D. Veber, R. Freidinger, 1982 .

A super active cyclic hexapeptide analog of somatostatin.

D. Veber, R. Freidinger, R. Nutt, 1984, Life sciences.

Synthesis of 9-fluorenylmethyloxycarbonyl-protected N-alkyl amino acids by reduction of oxazolidinones

R. Freidinger, D. Perlow, Jeffery S. Hinkle, 1983 .

A potent and orally active HIV-1 integrase inhibitor.

Wei Xu, D. Hazuda, Michael D. Miller, 2007, Bioorganic & medicinal chemistry letters.

The selectivity of statine-based inhibitors against various human aspartic proteinases.

D. Veber, B. Dunn, S. D. de Laszlo, 1990, The Biochemical journal.

1-(((7,7-Dimethyl-2(S)-(2(S)-amino-4-(methylsulfonyl)butyramido) bicyclo(2.2.1)heptan-1(S)-yl)methyl)sulfonyl)-4-(2-methylphenyl) piperazine (L-368,899): An Orally Bioavailable, Non-Peptide Oxytocin Antagonist with Potential Utility for Managing Preterm Labor.

B. E. Evans, M. Bock, R. Freidinger, 1994 .

Nonpeptide oxytocin antagonists: analogs of L-371,257 with improved potency.

B. E. Evans, M A Jacobson, M. Bock, 1999, Bioorganic & medicinal chemistry letters.

Development of a novel class of cyclic hexapeptide oxytocin antagonists based on a natural product.

M. Bock, W. L. Whitter, G. F. Lundell, 1992, Journal of medicinal chemistry.

Renin inhibitors. Syntheses of subnanomolar, competitive, transition-state analogue inhibitors containing a novel analogue of statine.

T. Lin, M. Poe, J. Boger, 1985, Journal of medicinal chemistry.

Bioactive conformation of luteinizing hormone-releasing hormone: evidence from a conformationally constrained analog.

D. Veber, R. Freidinger, R Saperstein, 1980, Science.

Methyl-substitution of an iminohydantoin spiropiperidine β-secretase (BACE-1) inhibitor has a profound effect on its potency.

A. Simon, G. McGaughey, J. Barrow, 2015, Bioorganic & medicinal chemistry letters.

Use of N-Fmoc amino acid chlorides and activated 2-(fluorenylmethoxy)-5(4H)-oxazolones in solid-phase peptide synthesis. Efficient syntheses of highly N-alkylated cyclic hexapeptide oxytocin antagonists related to L-365,209

Roger M. Freidinger, Peter D. Williams, D. Veber, 1992 .

Practical Synthesis of 4‐Fluoro‐2‐(methylthio)benzylamine and the Corresponding Sulfone and Sulfonamide

J. Wai, M. Egbertson, D. Perlow, 2007 .

Conformationally constrained tachykinin analogs which are selective ligands for the eledoisin binding site.

D. Veber, R. Freidinger, J. Maguire, 1986, Molecular pharmacology.

Angiotensin-converting enzyme inhibitors: synthesis and biological activity of acyl tripeptide analogues of enalapril.

W. Greenlee, A. Patchett, E. Ulm, 1985, Journal of medicinal chemistry.

Characterization of Tachykinin Receptors by Ligand Binding Studies and by Utilization of Conformationally Restricted Tachykinin Analogues

D. Veber, R. Freidinger, B. Williams, 1986 .

Synthesis of 9-fluorenylmethyloxycarbonyl-protected N-alkyl amino acids by reduction of oxazolidinones

R. Freidinger, D. Perlow, Jeffery S. Hinkle, 1983 .

Conformational modifications of cyclic hexapeptide somatostatin analogs.

D. Veber, R. Freidinger, W. Randall, 2009, International journal of peptide and protein research.

Conformationally constrained o-tolylpiperazine camphorsulfonamide oxytocin antagonists. Structural modifications that provide high receptor affinity and suggest a bioactive conformation.

D. Veber, R. Freidinger, R. Ball, 1994, Bioorganic & medicinal chemistry.

Renin inhibitors containing conformationally restricted P1-P1' dipeptide mimetics.

R J Lynch, M. Holloway, J. Doyle, 1991, Journal of medicinal chemistry.

Novel oxytocin antagonists

B. E. Evans, D. Veber, M. Bock, 1993 .

Potent and selective cyclic hexapeptide oxytocin antagonists

D. Veber, M. Bock, R. M. Dipardo, 1991 .

Potent and Selective Oxytocin Antagonists Obtained by Chemical Modification of a Streptomyces Silvensis Derived Cyclic Hexapeptide and by Total Synthesis

D. Veber, M. Bock, R. M. Dipardo, 1990 .

Orally active, non-peptide oxytocin antagonists

B. E. Evans, D. Veber, M. Bock, 1994 .

Synthesis of new peptides based on models of receptor-bound conformation.

D. Veber, R. Freidinger, W. L. Whitter, 1987, Psychopharmacology series.