S. Durón

发表

Design of Selective PAK1 Inhibitor G-5555: Improving Properties by Employing an Unorthodox Low-pK a Polar Moiety.

Xianrui Zhao, Ignacio Aliagas, Ronen Marmorstein, 2015, ACS medicinal chemistry letters.

Group I Paks as therapeutic targets in NF2-deficient meningioma

D. Welling, K. Hoeflich, J. Chernoff, 2015, Oncotarget.

Reactivity-based one-pot total synthesis of fucose GM1 oligosaccharide: A sialylated antigenic epitope of small-cell lung cancer

Chi‐Huey Wong, S. Durón, T. K. Mong, 2003, Proceedings of the National Academy of Sciences of the United States of America.

Selectfluor: mechanistic insight and applications.

Chi‐Huey Wong, M. Burkart, S. Durón, 2004, Angewandte Chemie.

FRAX597, a Small Molecule Inhibitor of the p21-activated Kinases, Inhibits Tumorigenesis of Neurofibromatosis Type 2 (NF2)-associated Schwannomas*

S. Licciulli, J. Kissil, J. Maksimoska, 2013, The Journal of Biological Chemistry.

Annulation of thioimidates and vinyl carbodiimides to prepare 2-aminopyrimidines, competent nucleophiles for intramolecular alkyne hydroamination. Synthesis of (-)-crambidine.

N. Ide, D. Gin, S. Durón, 2010, Journal of the American Chemical Society.

Sulfide-mediated dehydrative glycosylation.

Hien M. Nguyen, H. M. Nguyen, D. Gin, 2001, Journal of the American Chemical Society.

Total synthesis of (+)-batzelladine A and (-)-batzelladine D via [4 + 2]-annulation of vinyl carbodiimides with N-alkyl imines.

D. Gin, S. Durón, Kendall Day, 2006, Journal of the American Chemical Society.

N-(Phenylthio)-ε-caprolactam: A New Promoter for the Activation of Thioglycosides

Chi‐Huey Wong, S. Durón, Tuelay Polat, 2004 .

Diastereoselective [4+2] annulation of vinyl carbodiimides with N-alkyl imines. Asymmetric synthetic access to the batzelladine alkaloids.

D. Gin, S. Durón, M. Arnold, 2005, Journal of the American Chemical Society.

Synthesis and determination of absolute configuration of the bicyclic guanidine core of batzelladine A.

D. Gin, S. Durón, 2001, Organic letters.

Heteroaromatic-aminomethyl quinolones: potent and selective iNOS inhibitors.

Nahid M. Yazdani, T. Rao, A. Shiau, 2012, Bioorganic & medicinal chemistry letters.

Rescue of fragile X syndrome phenotypes in Fmr1 KO mice by the small-molecule PAK inhibitor FRAX486

S. Tonegawa, A. Govindarajan, Se-Young Choi, 2013, Proceedings of the National Academy of Sciences.

p21-Activated kinase 1 is required for efficient tumor formation and progression in a Ras-mediated skin cancer model.

A. Jubb, K. Hoeflich, J. Gutkind, 2012, Cancer research.

PAKs inhibitors ameliorate schizophrenia-associated dendritic spine deterioration in vitro and in vivo during late adolescence

A. Hayashi‐Takagi, H. Kasai, R. Huganir, 2014, Proceedings of the National Academy of Sciences.

Small molecule inhibition of group I p21-activated kinases in breast cancer induces apoptosis and potentiates the activity of microtubule stabilizing agents

I. Ellis, S. Chin, C. Caldas, 2015, Breast Cancer Research.

FRAX 597 , a Small Molecule Inhibitor of the p 21-activated Kinases , Inhibits Tumorigenesis of Neurofibromatosis Type 2 ( NF 2 )-associated Schwannomas *

S. Licciulli, J. Kissil, J. Maksimoska, 2013 .

Therapeutics , Targets , and Chemical Biology p 21-Activated Kinase 1 Is Required for Ef fi cient Tumor Formation and Progression in a Ras-Mediated Skin Cancer Model

Ich, A. Jubb, J. Gutkind, 2012 .

Inhibiteurs de la cystathionine- γ -lyase (cse)

S. Durón, S. Sydserff, G. Stein, 2013 .

Small molecule inhibition of group I p21-activated kinases in breast cancer induces apoptosis and potentiates the activity of microtubule stabilizing agents

I. Ellis, S. Chin, C. Caldas, 2015, Breast Cancer Research.

PAKs inhibitors ameliorate schizophrenia-associated dendritic spine deterioration in vitro and in vivo during late adolescence

H. Kasai, R. Huganir, Zhen Yan, 2014, Proceedings of the National Academy of Sciences.

1 Therapeutics, Targets, and Chemical Biology

A. Jubb, K. Hoeflich, J. Gutkind, 2012 .