Zunhua Yang

发表

Design and synthesis of tetrahydropyridopyrimidine derivatives as dual GPR119 and DPP-4 modulators.

Yuyuan Li, Yi Jin, Yuanying Fang, 2019, Bioorganic chemistry.

Stereoselective synthesis of (−)-centrolobine

Zunhua Yang, Hee-doo Kim, 2014 .

The new opportunities in medicinal chemistry of fourth-generation EGFR inhibitors to overcome C797S mutation.

Shan Xu, Pengwu Zheng, Wufu Zhu, 2020, European journal of medicinal chemistry.

Design, synthesis, antiproliferative activity and docking studies of quinazoline derivatives bearing 2,3-dihydro-indole or 1,2,3,4-tetrahydroquinoline as potential EGFR inhibitors.

Hong Zhang, Z. Lan, Wensheng Zou, 2018, European journal of medicinal chemistry.

Discovery of novel quinazoline derivatives bearing semicarbazone moiety as potent EGFR kinase inhibitors

Pengwu Zheng, Wufu Zhu, Y. Tu, 2018, Computational and structural biotechnology journal.

A novel carbazole derivative, MHY407, sensitizes cancer cells to doxorubicin-, etoposide-, and radiation treatment via DNA damage.

Sungpil Yoon, H. Moon, Hyung Sik Kim, 2012, European journal of pharmacology.

Design, Synthesis, and Biological Evaluation of Novel Thienopyrimidine Derivatives as PI3Kα Inhibitors

Yuanying Fang, Pengwu Zheng, Wufu Zhu, 2019, Molecules.

Improved antiproliferative activity of novel Pulsatilla saponin D/α-hederin derivatives containing nitric oxide donors

Yi Jin, Yulin Feng, Yuanying Fang, 2020 .

GPR119 agonists for the treatment of type 2 diabetes: an updated patent review (2014-present)

Yuanying Fang, Zunhua Yang, Huilan Li, 2021, Expert opinion on therapeutic patents.

Design, synthesis and biological evaluation of substituted 2-(thiophen-2-yl)-1,3,5-triazine derivatives as potential dual PI3Kα/mTOR inhibitors.

Qingqing Jin, Shan Xu, Pengwu Zheng, 2019, Bioorganic chemistry.

Synthesis and evaluation of novel fused pyrimidine derivatives as GPR119 agonists.

Yi Jin, Yang Wan, Yuanying Fang, 2019, Bioorganic chemistry.

Synthesis and biological evaluation of pyrimidine derivatives with diverse azabicyclic ether/amine as novel GPR119 agonist.

Yuanying Fang, Zunhua Yang, Haeil Park, 2017, Bioorganic & medicinal chemistry letters.

Novel 5-nitropyrimidine derivatives bearing endo-azabicyclic alcohols/amines as potent GPR119 agonists.

Yuanying Fang, Zunhua Yang, Jongkook Lee, 2017, Bioorganic & Medicinal Chemistry.

Synthesis and biological evaluation of novel 2,4-disubstituted quinazoline analogues as GPR119 agonists.

Tuan-Anh N. Pham, Yuanying Fang, Zunhua Yang, 2013, Bioorganic & medicinal chemistry.

Synthesis and biological evaluation of 5-nitropyrimidine analogs with azabicyclic substituents as GPR119 agonists.

Tuan-Anh N. Pham, Yuanying Fang, Zunhua Yang, 2013, Bioorganic & medicinal chemistry letters.

Design, Synthesis, Antitumor Activity and Mode of Action of Novel Oxiranyl and Thiiranyl Phenol Derivatives.

H. Moon, L. Jeong, Hyung Sik Kim, 2009 .

Design, synthesis and evaluation of anti-proliferative activity of 2-aryl-4-aminoquinazoline derivatives as EGFR inhibitors.

Shan Xu, Pengwu Zheng, Wufu Zhu, 2021, Bioorganic chemistry.

Discovery of Triazolo-pyridazine/-pyrimidine Derivatives Bearing Aromatic (Heterocycle)-Coupled Azole Units as Class II c-Met Inhibitors

Wenhui Gan, Shan Xu, Xiaobo Liu, 2020, ACS omega.

Design and synthesis of novel senkyunolide analogues as neuroprotective agents.

Rikang Wang, Yi Jin, Yuanying Fang, 2018, Bioorganic & medicinal chemistry letters.

Optimisation of novel 4, 8-disubstituted dihydropyrimido[5,4-b][1,4]oxazine derivatives as potent GPR 119 agonists

Yi Jin, Yuanying Fang, Ronghua Liu, 2019, Journal of enzyme inhibition and medicinal chemistry.

Design and synthesis of novel pyrimido[5,4-d]pyrimidine derivatives as GPR119 agonist for treatment of type 2 diabetes.

Yi Jin, Yuanying Fang, Wufu Zhu, 2018, Bioorganic & medicinal chemistry.

Coumarin-dithiocarbamate hybrids as novel multitarget AChE and MAO-B inhibitors against Alzheimer's disease: Design, synthesis and biological evaluation.

Yi Jin, Jiaoli Ding, Jing Liu, 2018, Bioorganic chemistry.

Highly Concise Synthesis of 3'‐"Up"‐ethynyl‐5'‐methylbicyclo‐ [3.1.0]hexyl Purine and Pyrimidine Nucleoside Derivatives Using Rhodium(II) Carbenoid Cycloaddition and Highly Diastereoselective Grignard Reaction

Boeun Lee, H. Moon, L. Jeong, 2009 .

Nitric oxide-donating derivatives of hederacolchiside A1: Synthesis and biological evaluation in vitro and in vivo as potential anticancer agents.

Rikang Wang, Yi Jin, Yuanying Fang, 2017, Bioorganic & medicinal chemistry letters.

Development and Validation of a Phenotypic High-Content Imaging Assay for Assessing the Antiviral Activity of Small-Molecule Inhibitors Targeting Zika Virus

Yan Liu, Rongshi Li, J. Bernatchez, 2018, Antimicrobial Agents and Chemotherapy.

Synthesis of Halogenated 1,5-Diarylimidazoles and Their Inhibitory Effects on LPS-Induced PGE2 Production in RAW 264.7 Cells

Kyung-Tae Lee, Yuanying Fang, Zunhua Yang, 2021, Molecules.

Synthesis of 1,5-diarylhaloimidazole analogs and their inhibitory activities against PGE₂ production from LPS-treated RAW 264.7 cells.

Tuan-Anh N. Pham, Sung-soo Kim, Zunhua Yang, 2012, Bioorganic & medicinal chemistry.

Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors for the treatment of non-small cell lung cancer: a patent review (2014-present)

Shan Xu, Pengwu Zheng, Wufu Zhu, 2020, Expert opinion on therapeutic patents.

Novel 2,6-disubstituted benzofuran-3-one analogues improve cerebral ischemia/reperfusion injury via neuroprotective and antioxidative effects.

Yulin Feng, Yang Wan, Yuanying Fang, 2023, Bioorganic chemistry.

Design, synthesis and 3D-QSAR analysis of novel thiopyranopyrimidine derivatives as potential antitumor agents inhibiting A549 and Hela cancer cells.

Z. Lan, Shan Xu, Pengwu Zheng, 2019, European journal of medicinal chemistry.

Discovery of thiapyran-pyrimidine derivatives as potential EGFR inhibitors.

Shan Xu, Pengwu Zheng, Wufu Zhu, 2020, Bioorganic & medicinal chemistry.

Design, synthesis and antitumor activity of novel thiophene-pyrimidine derivatives as EGFR inhibitors overcoming T790M and L858R/T790M mutations.

Liying Yu, Shan Xu, Pengwu Zheng, 2020, European journal of medicinal chemistry.

Synthesis and biological evaluation of Hederacolchiside A1 derivatives as anticancer agents.

Rikang Wang, Yi Jin, H. Ouyang, 2016, Bioorganic & medicinal chemistry letters.

Synthesis, Biological Evaluation, and Mode of Action of Pulsatilla Saponin D Derivatives as Promising Anticancer Agents

Yi Jin, Yuanying Fang, Shiling Yang, 2019, Frontiers in Pharmacology.

Straightforward and Facile Synthesis of a Bioactive Component from Zingiber cassumunar Roxb.

Yuanying Fang, Zunhua Yang, Haeil Park, 2014 .

Novel fluorinated pyrrolomycins as potent anti-staphylococcal biofilm agents: Design, synthesis, pharmacokinetics and antibacterial activities.

Yan Liu, Jialin C. Zheng, Zhen Qiao, 2016, European journal of medicinal chemistry.

Synthesis and bioevaluation of thienopyrimidines bearing a pyrazoline unit as selective PI3Kα inhibitors

Zixin Luo, Shan Xu, Wufu Zhu, 2019, RSC Advances.

Effects of novel pyrrolomycin MP1 in MYCN amplified chemoresistant neuroblastoma cell lines alone and combined with temsirolimus

Yan Liu, Yan Liu, Zhen Qiao, 2019, BMC Cancer.

Evaluation of novel paclitaxel-loaded NO-donating polymeric micelles for an improved therapy for gastroenteric tumor

Yi Jin, Yuanying Fang, Ronghua Liu, 2021, New Journal of Chemistry.

Effects of novel pyrrolomycin MP1 in MYCN amplified chemoresistant neuroblastoma cell lines alone and combined with temsirolimus

Yan Liu, Zhen Qiao, Rongshi Li, 2019, BMC Cancer.

Development and validation of a phenotypic high-content imaging assay for assessing the antiviral activity of small-molecule inhibitors targeting the Zika virus

Yan Liu, Rongshi Li, J. Bernatchez, 2018, bioRxiv.

Design, Synthesis and Biological Evaluation of Novel Phenylsulfonylurea Derivatives as PI3K/mTOR Dual Inhibitors

Shan Xu, Wufu Zhu, Wei Li, 2018, Molecules.

Discovery of [1,2,4]triazolo[4,3-a]pyrazine derivatives bearing a 4-oxo-pyridazinone moiety as potential c-Met kinase inhibitors

Shan Xu, Xiaobo Liu, Hehua Xiong, 2020, New Journal of Chemistry.

A novel carbazole derivative, MHY407, sensitizes cancer cells to doxorubicin-, etoposide-, and radiation treatment via DNA damage.

Sungpil Yoon, H. Moon, Hyung Sik Kim, 2012, European journal of pharmacology.

Nitric oxide/paclitaxel micelles enhance anti-liver cancer effects and paclitaxel sensitivity by inducing ferroptosis, endoplasmic reticulum stress and pyroptosis

Zunhua Yang, Huilan Li, Xiaoyu Deng, 2023, RSC advances.

Development and Validation of a Phenotypic High-Content Imaging Assay for Assessing the Antiviral Activity of Small-Molecule Inhibitors Targeting Zika Virus

Yan Liu, Rongshi Li, J. Siqueira-Neto, 2018, Antimicrobial Agents and Chemotherapy.

Lipid lowering activity of (E)-3-[4-[2-(4-chlorophenoxy)-2-methylpropanoylox y]-3-methoxyphenyl] acrylic acid (AZ) in hyperlipidemic rats

Zunhua Yang, Hong Peng, Jun Xu, 2011, 2011 International Conference on Remote Sensing, Environment and Transportation Engineering.