Shanta Bist

Pyrrolamide DNA Gyrase Inhibitors: Fragment-Based Nuclear Magnetic Resonance Screening To Identify Antibacterial Agents

Ning Gao, Haihong Ni, Oluyinka Green, 2011, Antimicrobial Agents and Chemotherapy.

Optimization of pyrrolamide topoisomerase II inhibitors toward identification of an antibacterial clinical candidate (AZD5099).

G. Basarab, A. Eakin, C. Garner, 2014, Journal of medicinal chemistry.

Pyrrolamide DNA gyrase inhibitors: optimization of antibacterial activity and efficacy.

G. Basarab, A. Eakin, A. Boriack-Sjodin, 2011, Bioorganic & medicinal chemistry letters.

Fragment-to-hit-to-lead discovery of a novel pyridylurea scaffold of ATP competitive dual targeting type II topoisomerase inhibiting antibacterial agents.

G. Basarab, A. Eakin, P. Boriack-Sjodin, 2013, Journal of medicinal chemistry.

Discovery of a novel azaindole class of antibacterial agents targeting the ATPase domains of DNA gyrase and Topoisomerase IV.

P. Boriack-Sjodin, K. Hull, J. Manchester, 2012, Bioorganic & medicinal chemistry letters.