M. Mayer

发表

Characterization of Ligand Binding by Saturation Transfer Difference NMR Spectroscopy.

Bernd Meyer, B. Meyer, Moriz Mayer, 1999, Angewandte Chemie.

Discovery of ligands by a combination of computational and NMR-based screening: RNA as an example target.

T. James, M. Mayer, 2005, Methods in enzymology.

Saturation transfer difference NMR spectroscopy for identifying ligand epitopes and binding specificities.

O Hindsgaul, B. Meyer, M. Palcic, 2004, Ernst Schering Research Foundation workshop.

Drugging an undruggable pocket on KRAS

M. Koegl, S. Fesik, A. Waterson, 2019, Proceedings of the National Academy of Sciences.

Using 31P NMR Spectroscopy at 14.1 Tesla to Investigate PARP-1 Associated Energy Failure and Metabolic Rescue in Cerebrocortical Slices

R. Swanson, T. James, Guo-Yuan Yang, 2004, Journal of bioenergetics and biomembranes.

A medicinal chemistry perspective on melting point: matched molecular pair analysis of the effects of simple descriptors on the melting point of drug-like compounds

E. Haaksma, R. Leurs, Andreas Steffen, 2012 .

Getting a Grip on the Undrugged: Targeting β‐Catenin with Fragment‐Based Methods

Julian E. Fuchs, M. Pearson, D. Breitsprecher, 2020, ChemMedChem.

Fragment-based discovery of a chemical probe for the PWWP1 domain of NSD3

Julian E. Fuchs, O. Fedorov, C. Arrowsmith, 2019, Nature Chemical Biology.

Fragment Optimization of Reversible Binding to the Switch II Pocket on KRAS Leads to a Potent, In Vivo Active KRASG12C Inhibitor

A. Waterson, D. Rudolph, M. Gmachl, 2022, Journal of medicinal chemistry.

Reply to Tran et al.: Dimeric KRAS protein–protein interaction stabilizers

M. Koegl, S. Fesik, A. Waterson, 2020, Proceedings of the National Academy of Sciences.

Microwave-assisted parallel synthesis of fused heterocycles in a novel parallel multimode reactor.

T. Karner, A. Stadler, M. Mayer, 2008, Journal of combinatorial chemistry.

Synthesis and testing of a focused phenothiazine library for binding to HIV-1 TAR RNA.

R Kiplin Guy, R. Guy, P. T. Lang, 2006, Chemistry & biology.

NMR-based characterization of phenothiazines as a RNA binding scaffold.

T. James, Moriz Mayer, Thomas L James, 2004, Journal of the American Chemical Society.

Detailed structure-activity relationship of indolecarboxamides as H4 receptor ligands.

R. Smits, I. D. de Esch, O. Zuiderveld, 2012, European journal of medicinal chemistry.

Group epitope mapping by saturation transfer difference NMR to identify segments of a ligand in direct contact with a protein receptor.

B. Meyer, M Mayer, B Meyer, 2001, Journal of the American Chemical Society.

Chemically Induced Degradation of the Oncogenic Transcription Factor BCL6.

M. Koegl, P. Ettmayer, T. Voss, 2017, Cell reports.

Intracellular Trapping of the Selective Phosphoglycerate Dehydrogenase (PHGDH) Inhibitor BI-4924 Disrupts Serine Biosynthesis.

P. Ettmayer, W. Sommergruber, M. Pearson, 2019, Journal of medicinal chemistry.

Bispyrimidines as potent histamine H(4) receptor ligands: delineation of structure-activity relationships and detailed H(4) receptor binding mode.

I. D. de Esch, O. Zuiderveld, E. Haaksma, 2013, Journal of medicinal chemistry.

Start selective and rigidify: The discovery path towards a next generation of EGFR tyrosine kinase inhibitors.

Julian E. Fuchs, P. Ettmayer, A. Baum, 2019, Journal of medicinal chemistry.

Chemically Induced Degra dation of the Oncogenic Transcription Factor BCL 6 Graphical Abstract Highlights

M. Koegl, P. Ettmayer, T. Voss, 2022 .

NMR Applications to Find and Progress TREX1 Binders

Julian E. Fuchs, L. Geist, M. Mayer, 2022, Journal of Magnetic Resonance Open.

The Photochemistry of Thymidylyl-(3′-5′)-5-methyl-2′-deoxycytidine in Aqueous Solution¶

M. Mayer, L. Celewicz, M. D. Shetlar, 2005 .

The Photochemistry of Thymidylyl‐(3′‐5′)‐5‐methyl‐2′‐deoxycytidine in Aqueous Solution ¶

M. Mayer, L. Celewicz, M. D. Shetlar, 2005, Photochemistry and photobiology.

A Step toward NRF2‐DNA Interaction Inhibitors by Fragment‐Based NMR Methods

Julian E. Fuchs, R. Konrat, Sven Brüschweiler, 2021, ChemMedChem.

Inverse PI by NMR: Analysis of Ligand 1H-Chemical Shifts in the Protein-Bound State

Julian E. Fuchs, R. Konrat, J. Böttcher, 2021, bioRxiv.

KRAS Binders Hidden in Nature

Gabriella Siszler, G. Fischer, A. Bergner, 2019, Chemistry.

PI by NMR: Probing CH–π Interactions in Protein–Ligand Complexes by NMR Spectroscopy

Julian E. Fuchs, R. Konrat, Sven Brüschweiler, 2020, Angewandte Chemie.

A selective and orally bioavailable VHL-recruiting PROTAC achieves SMARCA2 degradation in vivo

Julian E. Fuchs, M. Koegl, Barbara Mair, 2022, Nature Communications.

Direct NMR Probing of Hydration Shells of Protein Ligand Interfaces and Its Application to Drug Design.

R. Konrat, L. Geist, M. Mayer, 2017, Journal of medicinal chemistry.

Mapping the active site of angiotensin-converting enzyme by transferred NOE spectroscopy.

B. Meyer, M Mayer, B Meyer, 2000, Journal of medicinal chemistry.

DETECTING BINDING AFFINITY TO IMMOBILIZED RECEPTOR PROTEINS IN COMPOUND LIBRARIES BY HR-MAS STD NMR

Jens Klein, Bernd Meyer, B. Meyer, 1999 .

Detecting ligand binding to a small RNA target via saturation transfer difference NMR experiments in D(2)O and H(2)O.

T. James, Moriz Mayer, Thomas L James, 2002, Journal of the American Chemical Society.

Characterization of Ligand Binding by Saturation Transfer Difference NMR Spectroscopy.

B. Meyer, M. Mayer, 1999, Angewandte Chemie.

Ligand 1 H NMR Chemical Shifts as Accurate Reporters for Protein-Ligand Binding Interfaces in Solution.

R. Konrat, P. A. Sánchez‐Murcia, L. Geist, 2023, Chemphyschem : a European journal of chemical physics and physical chemistry.