S. Thiele

发表

Design, synthesis, and biological evaluation of scaffold-based tripeptidomimetic antagonists for CXC chemokine receptor 4 (CXCR4).

M. Rosenkilde, B. Haug, T. Fossen, 2014, Bioorganic & medicinal chemistry.

Trabectedin Reduces Skeletal Prostate Cancer Tumor Size in Association with Effects on M2 Macrophages and Efferocytosis12

Y. Shiozawa, L. Hofbauer, L. Mccauley, 2018, Neoplasia.

Probing the molecular interactions between CXC chemokine receptor 4 (CXCR4) and the tripeptidomimetic antagonist KRH‐ 1636

M. Rosenkilde, B. Haug, Zack G Zachariassen, 2016 .

Biased and Constitutive Signaling in the CC-chemokine Receptor CCR5 by Manipulating the Interface between Transmembrane Helices 6 and 7*

D. Guo, T. Frimurer, M. Rosenkilde, 2013, The Journal of Biological Chemistry.

Reversed binding of a small molecule ligand in homologous chemokine receptors – differential role of extracellular loop 2

T. Frimurer, M. Rosenkilde, R. Kolbeck, 2012, British journal of pharmacology.

Influence of median sternotomy on the psychosomatic outcome in coronary artery single-vessel bypass grafting.

V. Gulielmos, S. Tugtekin, S. Schueler, 1999, European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery.

Interleukin-1, interleukin-6 and myocardial enzyme response after coronary artery bypass grafting - a prospective randomized comparison of the conventional and three minimally invasive surgical techniques.

V. Gulielmos, S. Tugtekin, S. Schueler, 2000, European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery.

Multistep continuous-flow synthesis in medicinal chemistry: discovery and preliminary structure-activity relationships of CCR8 ligands.

A. Ritzén, M. Rosenkilde, T. Ulven, 2013, Chemistry.

Short-term Changes in hsCRP and NT-proBNP Levels in Hypertensive Emergencies

H. Wallaschofski, T. Lohmann, S. Thiele, 2008, Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme.

Stimulation of bone formation by monocyte-activator functionalized graphene oxide in vivo.

Gianaurelio Cuniberti, Chiara Gardin, Marco Orecchioni, 2019, Nanoscale.

Total body Na(+)-depletion without hyponatraemia can trigger overtraining-like symptoms with sleeping disorders and increasing blood pressure: explorative case and literature study.

M. Blank, J. Unger, S. Thiele, 2012, Medical hypotheses.

Plasma levels of Semaphorin 4D are decreased by adjuvant tamoxifen but not aromatase inhibitor therapy in breast cancer patients

T. Rachner, L. Hofbauer, M. Rauner, 2019, Journal of bone oncology.

Chronic sympathetic activation promotes downregulation of β-adrenoceptor-mediated effects in the guinea pig heart independently of structural remodeling and systolic dysfunction

S. Olesen, S. Thiele, O. Osadchii, 2011, Pflügers Archiv - European Journal of Physiology.

Structure-activity relationship studies of the aromatic positions in cyclopentapeptide CXCR4 antagonists.

M. Rosenkilde, J. Mungalpara, Zack G Zachariassen, 2013, Organic & biomolecular chemistry.

The beneficial effects of calcium channel blockers on long‐term kidney transplant survival are independent of blood‐pressure reduction

B. Suwelack, H. Hohage, S. Thiele, 2000, Clinical transplantation.

Investigations on the effects of heavy water (D2O) on the functional activity of human platelets.

S. Thiele, J. Fischer, H. Reuter, 1985, Haemostasis.

Targeting syndecan-1 in breast cancer inhibits osteoclast functions through up-regulation of osteoprotegerin

T. Rachner, L. Hofbauer, M. Rauner, 2013, Journal of bone oncology.

Biased and G Protein-Independent Signaling of Chemokine Receptors

M. Rosenkilde, O. Larsen, S. Thiele, 2014, Front. Immunol..

Immune reactivity is more suppressed in patients with alcoholic liver disease than in patients with virus-induced cirrhosis after CRH stimulation.

Peter Neuhaus, Stefanie Thiele, P. Neuhaus, 2006, Alcoholism, clinical and experimental research.

Gating function of isoleucine‐116 in TM‐3 (position III:16/3.40) for the activity state of the CC‐chemokine receptor 5 (CCR5)

D. Guo, T. Frimurer, M. Rosenkilde, 2014, British journal of pharmacology.

Allosteric and Orthosteric Sites in CC Chemokine Receptor (CCR5), a Chimeric Receptor Approach*

T. Frimurer, M. Rosenkilde, J. Mokrosiński, 2011, The Journal of Biological Chemistry.

WNT5A and Its Receptors in the Bone‐Cancer Dialogue

T. Rachner, M. Rauner, S. Thiele, 2016, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Role of WNT5A receptors FZD5 and RYK in prostate cancer cells

M. Wirth, T. Rachner, L. Hofbauer, 2018, Oncotarget.

miR‐9 enhances IL‐2 production in activated human CD4+ T cells by repressing Blimp‐1

H. Jäck, A. Pahl, J. Wittmann, 2012, European journal of immunology.

Molecular requirements for inhibition of the chemokine receptor CCR8 – probe‐dependent allosteric interactions

A. Johnsen, R. Kolbeck, J. Pease, 2012, British journal of pharmacology.

Combined inhibition of the mevalonate pathway with statins and zoledronic acid potentiates their anti-tumor effects in human breast cancer cells.

T. Rachner, L. Hofbauer, A. Browne, 2016, Cancer letters.

Potentiated suppression of Dickkopf-1 in breast cancer by combined administration of the mevalonate pathway inhibitors zoledronic acid and statins

T. Rachner, L. Hofbauer, A. Browne, 2015, Breast Cancer Research and Treatment.

p38 MAPK regulates the Wnt inhibitor Dickkopf-1 in osteotropic prostate cancer cells

T. Rachner, L. Hofbauer, A. Browne, 2016, Cell Death and Disease.

Cognitive performance in dialysis patients - "when is the right time to test?"

S. Thiele, J. Hoyer, Brandon H Greene, 2021, BMC Nephrology.

Determination of the binding mode for the cyclopentapeptide CXCR4 antagonist FC131 using a dual approach of ligand modifications and receptor mutagenesis

M. Rosenkilde, J. Mungalpara, S. Thiele, 2014, British journal of pharmacology.

Rational design of conformationally constrained cyclopentapeptide antagonists for C-x-C chemokine receptor 4 (CXCR4).

M. Rosenkilde, J. Mungalpara, S. Thiele, 2012, Journal of medicinal chemistry.

CXC Chemokine Receptor 7 (CXCR7) Regulates CXCR4 Protein Expression and Capillary Tuft Development in Mouse Kidney

S. Schulz, F. Mackay, S. Nietzsche, 2012, PloS one.

High serum levels of Dickkopf-1 are associated with a poor prognosis in prostate cancer patients

M. Wirth, T. Rachner, L. Hofbauer, 2014, BMC Cancer.

Discovery and Mapping of an Intracellular Antagonist Binding Site at the Chemokine Receptor CCR2

A. IJzerman, H. de Vries, L. Heitman, 2014, Molecular Pharmacology.

Positive Versus Negative Modulation of Different Endogenous Chemokines for CC-chemokine Receptor 1 by Small Molecule Agonists through Allosteric Versus Orthosteric Binding*

T. Schwartz, M. Rosenkilde, T. Ulven, 2008, Journal of Biological Chemistry.

Dickkopf-1 is regulated by the mevalonate pathway in breast cancer

T. Rachner, L. Hofbauer, C. Schem, 2014, Breast Cancer Research.

WNT5A Has Anti‐Prostate Cancer Effects In Vitro and Reduces Tumor Growth in the Skeleton In Vivo

T. Rachner, G. Baretton, C. Glüer, 2015, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Molecular Interaction of a Potent Nonpeptide Agonist with the Chemokine Receptor CCR8

T. Schwartz, M. Rosenkilde, S. Ghosh, 2007, Molecular Pharmacology.

Interaction of chemokines with their receptors--from initial chemokine binding to receptor activating steps.

M. Rosenkilde, S. Thiele, 2014, Current medicinal chemistry.

Extracellular Disulfide Bridges Serve Different Purposes in Two Homologous Chemokine Receptors, CCR1 and CCR5

M. Rosenkilde, A. H. Sparre-Ulrich, T. Ulven, 2013, Molecular Pharmacology.

WNT5A Has Anti‐Prostate Cancer Effects In Vitro and Reduces Tumor Growth in the Skeleton In Vivo

T. Rachner, G. Baretton, C. Glüer, 2015, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.