D. Rieman

发表

Discovery of orally active nonpeptide vitronectin receptor antagonists based on a 2-benzazepine Gly-Asp mimetic.

K. Ward, K. Erhard, R. Calvo, 2000, Journal of medicinal chemistry.

Identification and Cloning of a Connective Tissue Growth Factor-like cDNA from Human Osteoblasts Encoding a Novel Regulator of Osteoblast Functions*

John C. Lee, J. Trill, J. Lee, 1999, The Journal of Biological Chemistry.

Antagonism of the Osteoclast Vitronectin Receptor with an Orally Active Nonpeptide Inhibitor Prevents Cancellous Bone Loss in the Ovariectomized Rat

K. Ward, B. R. Smith, M. Lark, 2001, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

A Novel Human Bone Marrow Stroma-Derived Cell Line TF274 Is Highly Osteogenic In Vitro and In Vivo

U. Prabhakar, D. Lipshutz, I. James, 1998, Calcified Tissue International.

SB 239063, a p38 MAPK inhibitor, reduces neutrophilia, inflammatory cytokines, MMP-9, and fibrosis in lung.

John C. Lee, J. Adams, J. Adams, 2000, American journal of physiology. Lung cellular and molecular physiology.

First‐in‐Human Pharmacokinetics and Safety Study of GSK3008356, a Selective DGAT1 Inhibitor, in Healthy Volunteers

D. Rieman, Malek Okour, R. Brigandi, 2019, Clinical pharmacology in drug development.

Reduction of TGF‐beta activity abrogates growth promoting tumor cell‐cell interactions in vivo

R. Kerbel, D. Theodorescu, D. Rieman, 1991, Journal of cellular physiology.

Human Osteoclast Cathepsin K Is Processed Intracellularly Prior to Attachment and Bone Resorption

D. Veber, M. Lark, I. James, 2001, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Disease-modifying activity of SK&F 106615 in rat adjuvant-induced arthritis. Multiparameter analysis of disease magnetic resonance imaging and bone mineral density measurements.

S. Sarkar, A. Badger, B. Swift, 1996, Arthritis and rheumatism.

Phenylbutyrates as potent, orally bioavailable vitronectin receptor (integrin αvβ3) antagonists

K. Ward, R. Willette, T. Yue, 2003 .

Identification and characterization of a monoclonal antibody to an antigen expressed on activated macrophages.

G. Poste, K. Muirhead, D. Rieman, 1984, Proceedings of the National Academy of Sciences of the United States of America.

Orally bioavailable nonpeptide vitronectin receptor antagonists with efficacy in an osteoporosis model.

K. Erhard, R. Keenan, M. Lark, 1999, Bioorganic & medicinal chemistry letters.

Camptothecin hyper-resistant P388 cells: drug-dependent reduction in topoisomerase I content.

R. Hertzberg, G. Hofmann, M. Mattern, 1992, Oncology research.

Discovery of an imidazopyridine-containing 1,4-benzodiazepine nonpeptide vitronectin receptor (αvβ3) antagonist with efficacy in a restenosis model

B. Smith, T. Yue, E. Ohlstein, 1998 .

Benzimidazole derivatives as arginine mimetics in 1,4-benzodiazepine nonpeptide vitronectin receptor (αvβ3) antagonists

B. Smith, R. Calvo, R. Keenan, 1998 .

Biosynthesis and processing of cathepsin K in cultured human osteoclasts.

I. James, S. Hwang, R. Dodds, 2001, Bone.

Induction by immunomodulatory agents of a macrophage antigen recognized by monoclonal antibody 158.2 and correlation with macrophage function.

G. Poste, A. Badger, D. Rieman, 1985, Cellular immunology.

Cloning and Characterization of a Novel Integrin β3Subunit*

I. James, M. Gowen, J. Connor, 1997, The Journal of Biological Chemistry.

Idoxifene, a novel selective estrogen receptor modulator, is effective in a rat model of adjuvant-induced arthritis.

A. Badger, S. Hoffman, B. Swift, 1999, The Journal of pharmacology and experimental therapeutics.

Growth‐inhibitory activity of interferon‐beta against human colorectal carcinoma cell lines

D. Rieman, R. Greig, M. Anzano, 1989, International journal of cancer.

Cathepsin K, but Not Cathepsins B, L, or S, Is Abundantly Expressed in Human Osteoclasts (*)

C. Debouck, I. James, R. Dodds, 1996, The Journal of Biological Chemistry.

Evolution of tumor cell heterogeneity during progressive growth of individual lung metastases.

G Poste, G. Poste, J Tzeng, 1982, Proceedings of the National Academy of Sciences of the United States of America.

Production of C3 as a marker of lymphokine-mediated macrophage activation.

G. Poste, D. Rieman, R. Greig, 1984, Cellular immunology.

Differential expression of murine macrophage-mediated tumor cytotoxicity induced by interferons.

W. J. Johnson, G. Poste, D. Rieman, 1987, Cancer research.

Linking osteopetrosis and pycnodysostosis: Regulation of cathepsin K expression by the microphthalmia transcription factor family

D. Fisher, M. Horstmann, K. Weilbaecher, 2001, Proceedings of the National Academy of Sciences of the United States of America.

Growth factor production by human colon carcinoma cell lines.

D. Bowen-Pope, D. Rieman, R. Greig, 1989, Cancer research.

Disease-modifying activity of SB 242235, a selective inhibitor of p38 mitogen-activated protein kinase, in rat adjuvant-induced arthritis.

J. Boehm, John C. Lee, J. Adams, 2000, Arthritis and rheumatism.

Cloning and overexpression of TGF-beta 1 cDNA in a mammary adenocarcinoma: in vitro and in vivo effects.

N. Elshourbagy, R. Kerbel, D. Theodorescu, 1991, Growth factors.

Interleukin-1F7B (IL-1H4/IL-1F7) is processed by caspase-1 and mature IL-1F7B binds to the IL-18 receptor but does not induce IFN-gamma production.

John C. Lee, M. Lotze, Wentao Gao, 2002, Cytokine.

Inhibition of TGFα-induced second messengers by anti-EGF receptor antibody-425

U. Rodeck, D. Rieman, U. Murthy, 1990 .

Design and characterization of orally active Arg-Gly-Asp peptidomimetic vitronectin receptor antagonist SB 265123 for prevention of bone loss in osteoporosis.

K. Erhard, B. R. Smith, M. Lark, 1999, Journal of Pharmacology and Experimental Therapeutics.

Vascular Indications for Integrin αv Antagonists

T. Yue, J. Samanen, D. Rieman, 1997, Current Pharmaceutical Design.

Synthesis and evaluation of multisubstrate inhibitors of an oncogene-encoded tyrosine-specific protein kinase. 2.

G Poste, G. Poste, P. Bender, 1988, Journal of medicinal chemistry.

IL‐1‐ and TNF‐induced bone resorption is mediated by p38 mitogen activated protein kinase *

John C. Lee, A. Badger, B. Votta, 2001, Journal of cellular physiology.

Antagonism of TGF-alpha receptor binding and TGF-alpha induced stimulation of cell proliferation by methyl pheophorbides.

G. Chan, R. Johnson, D. Rieman, 1992, Oncology Research.

Identification and cloning of a human urea transporter HUT11, which is downregulated during adipogenesis of explant cultures of human bone

J. Mooney, L. Suva, M. Nuttall, 2000, Journal of cellular biochemistry.

A truncated v-abl-derived tyrosine-specific tyrosine kinase expressed in Escherichia coli.

G. Poste, M. Rosenberg, B. Ferguson, 1989, Biochemical Journal.

Cloning and characterization of a novel integrin beta3 subunit.

I. James, S. Hwang, M. Gowen, 1997, The Journal of biological chemistry.

Structure-function analysis of human transforming growth factor-alpha by site-directed mutagenesis.

G. Sathe, D. Rieman, J. Feild, 1992, Biochemical Journal.