S. Sands

发表

Varenicline: An α4β2 Nicotinic Receptor Partial Agonist for Smoking Cessation

Brian T. O’Neill, Yi Lu, Huang Jianhua, 2005 .

Blockade of the brain histamine H3 receptor by JNJ-39220675: preclinical PET studies with [11C]GSK189254 in anesthetized baboon

N. Carruthers, J. Fowler, J. Logan, 2012, Psychopharmacology.

In pursuit of alpha4beta2 nicotinic receptor partial agonists for smoking cessation: carbon analogs of (-)-cytisine.

F. Tingley, H. Rollema, B. O’Neill, 2005, Bioorganic & medicinal chemistry letters.

3,5-Bicyclic aryl piperidines: a novel class of alpha4beta2 neuronal nicotinic receptor partial agonists for smoking cessation.

F. Tingley, H. Rollema, B. O’Neill, 2005, Bioorganic & medicinal chemistry letters.

In pursuit of α4β2 nicotinic receptor partial agonists for smoking cessation: Carbon analogs of (−)-cytisine

F. Tingley, H. Rollema, B. O’Neill, 2005 .

Discovery of N-[(3R)-1-azabicyclo[2.2.2]oct-3-yl]furo[2,3-c]pyridine-5-carboxamide, an agonist of the alpha7 nicotinic acetylcholine receptor, for the potential treatment of cognitive deficits in schizophrenia: synthesis and structure--activity relationship.

Thomas J. Raub, E. Wong, R. Hurst, 2006, Journal of medicinal chemistry.

Synthesis and SAR studies of 1,4-diazabicyclo[3.2.2]nonane phenyl carbamates--subtype selective, high affinity alpha7 nicotinic acetylcholine receptor agonists.

R. J. Mather, C. J. O’Donnell, Frank M Nedza, 2009, Bioorganic & medicinal chemistry letters.

Discovery of 4-(5-methyloxazolo[4,5-b]pyridin-2-yl)-1,4-diazabicyclo[3.2.2]nonane (CP-810,123), a novel alpha 7 nicotinic acetylcholine receptor agonist for the treatment of cognitive disorders in schizophrenia: synthesis, SAR development, and in vivo efficacy in cognition models.

R. J. Mather, Anne W. Schmidt, R. Hurst, 2010, Journal of medicinal chemistry.

Varenicline: an alpha4beta2 nicotinic receptor partial agonist for smoking cessation.

F. Tingley, J. Heym, H. Rollema, 2005, Journal of medicinal chemistry.

Pharmacological Effects of Nicotine on Norepinephrine Metabolism in Rat Brown Adipose Tissue: Relevance to Nicotinic Therapies for Smoking Cessation

F. Tingley, M. Elwell, D. Brees, 2008, Toxicologic pathology.

Neuronal nicotinic acetylcholine receptor currents in phaeochromocytoma (PC12) cells: dual mechanisms of rectification.

S. Sands, M. Barish, 1992, The Journal of physiology.

REM sleep and in major depressive disorder

P. Bonaventure, W. Chai, C. Dvorak, 2012 .

A quantitative description of excitatory amino acid neurotransmitter responses on cultured embryonic Xenopus spinal neurons

S. Sands, M. Barish, 1989, Brain Research.

Calcium permeability of neuronal nicotinic acetylcholine receptor channels in PC12 cells

S. Sands, M. Barish, 1991, Brain Research.

3,5-Bicyclic aryl piperidines: A novel class of α4β2 neuronal nicotinic receptor partial agonists for smoking cessation

F. Tingley, H. Rollema, B. O’Neill, 2005 .

Pharmacological profile of the α4β2 nicotinic acetylcholine receptor partial agonist varenicline, an effective smoking cessation aid

R. J. Mather, R. Hurst, F. Tingley, 2007, Neuropharmacology.

Pharmacological profile of the alpha4beta2 nicotinic acetylcholine receptor partial agonist varenicline, an effective smoking cessation aid.

R. Hurst, F. Tingley, Y. Lu, 2007, Neuropharmacology.

Barium permeability of neuronal nicotinic receptor alpha 7 expressed in Xenopus oocytes.

J. Patrick, S. Sands, A. C. Costa, 1993, Biophysical journal.

Blockade of the brain histamine H3 receptor by JNJ-39220675: preclinical PET studies with [11C]GSK189254 in anesthetized baboon

N. Carruthers, J. Fowler, J. Logan, 2012, Psychopharmacology.

Charybdotoxin blocks voltage-gated K+ channels in human and murine T lymphocytes

M. Cahalan, Lewis, R. Lewis, 1989, The Journal of general physiology.

NMDA receptor activition by residual glutamate in glutamine preparations: a cautionary note regarding weak NMDA receptor agonists

S. Sands, M. Barish, 1989, Brain Research.

(3R,4S)-3-[4-(4-fluorophenyl)-4-hydroxypiperidin-1-yl]chroman-4,7-diol: a conformationally restricted analogue of the NR2B subtype-selective NMDA antagonist (1S,2S)-1-(4-hydroxyphenyl)-2-(4-hydroxy-4-phenylpiperidino)- 1-propanol.

F. Menniti, J. Blake, W. White, 1998, Journal of medicinal chemistry.

Novel benzamide-based histamine h3 receptor antagonists: the identification of two candidates for clinical development.

P. Bonaventure, Kiev S. Ly, T. Lovenberg, 2015, ACS Medicinal Chemistry Letters.

Translational Evaluation of JNJ-18038683, a 5-Hydroxytryptamine Type 7 Receptor Antagonist, on Rapid Eye Movement Sleep and in Major Depressive Disorder

P. Bonaventure, C. Dvorak, T. Lovenberg, 2012, Journal of Pharmacology and Experimental Therapeutics.

Varenicline: An α4β2 Nicotinic Receptor Partial Agonist for Smoking Cessation

J. Heym, H. Rollema, B. O’Neill, 2005 .