P. Luthra

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Computational analysis revealing that K634 and T681 mutations modulate the 3D-structure of PDGFR-β and lead to sunitinib resistance

Vishal Nemaysh, P. Luthra, 2017 .

Insilico study of the A2AR–D2R kinetics and interfacial contact surface for heteromerization

P. Luthra, Amresh Prakash, 2012, Amino Acids.

Modulation of macrophage defense responses by Mycobacterial persistence protein MprA (Rv0981) in human THP-1 cells: effect of single amino acid variation on host-pathogen interactions

K. Natarajan, Kausik Bhattacharyya, Shruti Jain, 2020, bioRxiv.

Bis((1,4-dimethyl-9H-carbazol-3-yl)methyl)amine-mediated anticancer effect triggered by sequence-specific cleavage of DNA leading to programmed cell death in the human U87 cell line

Rakesh Kumar, Nitin Kumar, Vishal Nemaysh, 2016 .

Modulation of indole ring annulation in ergoline template: chemistry, receptor binding and in vivo pharmacology with 6-OHDA model of Parkinson’s disease

P. Luthra, J. Senthil kumar, Rita Kumari, 2016, Medicinal Chemistry Research.

Exploring the binding and cleavage activities of nickelII complexes towards DNA and proteins

D. Masram, Manish Kumar, P. Luthra, 2021 .

A REVIEW ON ANTICANCER POTENTIAL OF SOME PYRANOCARBAZOLE ALKALOIDS AND ITS DERIVATIVES

Nitin Kumar, P. Luthra, Krishna K. Singh, 2021, International Journal of Advanced Research.

Design and synthesis of benzo[d]thiazol-2-yl-methyl-4-(substituted)-piperazine-1-carbothioamide as novel neuronal nitric oxide inhibitors and evaluation of their neuroprotecting effect in 6-OHDA-induced unilateral lesioned rat model of Parkinson's disease.

P. Luthra, S. Agrawal, Rita Kumari, 2022, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Inhibitors of tripeptidyl peptidase II. 2. Generation of the first novel lead inhibitor of cholecystokinin-8-inactivating peptidase: a strategy for the design of peptidase inhibitors.

J. Schwartz, P. B. Bishop, O. Peschard, 2000, Journal of medicinal chemistry.

Identification, Characterization and Partial Purification of Acid Phosphatase from Cotyledons of Psoralea corylifolia L.

S. Singh, P. Luthra, 2011 .

Role of proteins in resistance mechanism of Pseudomonas fluorescens against heavy metal induced stress with proteomics approach.

R. Sirdeshmukh, Y. Singh, C. S. Sundaram, 2006, Journal of biotechnology.

A reliable fluorimetric method to screen the nitric oxide synthase inhibitors in 96 well plate.

P. Luthra, S. Agrawal, Rita Kumari, 2019, Analytical biochemistry.

Pharmacological assessments of potent A2A receptor antagonist IDPU (1-(7-imino-3-propyl-2,3-dihydrothiazolo[4,5-d]pyrimidin-6(7H)-yl)urea) in rodent model of haloperidol induced Parkinson like symptoms

P. Luthra, S. Agrawal, N. Kumari, 2017, Neuroscience Letters.

A2A R mediated modulation in IP3 levels altering the [Ca2+]i through cAMP-dependent PKA signalling pathway.

P. Luthra, S. K. Barodia, Tuithung Sophronea, 2022, Biochimica et biophysica acta. General subjects.

Insilico study of the A2AR–D2R kinetics and interfacial contact surface for heteromerization

P. Luthra, Amresh Prakash, 2012, Amino Acids.

Synthesis and SARs of Coumarin Fused 1,5-Benzothiazepines as Novel Anticancer and Antioxidant Agents

Rakesh Kumar, M. Kidwai, P. Luthra, 2014 .

Synthesis of 2-oxo/thioxooctahydroquinazolin-5-one derivatives and their evaluation as anticancer agents.

Rakesh Kumar, M. Kidwai, D. Bhatnagar, 2010, Chemical & pharmaceutical bulletin.

Aqua mediated synthesis of 2-amino-6-benzothiazol-2-ylsulfanyl-chromenes and its in vitro study, explanation of the structure-activity relationships (SARs) as antibacterial agent.

S. Singh, M. Kidwai, P. Luthra, 2010, European journal of medicinal chemistry.

8-(Furan-2-yl)-3-phenethylthiazolo[5,4-e][1,2,4]triazolo[1,5-c]pyrimidine-2(3H)-thione as novel, selective and potent adenosine A2A receptor antagonist

C. B. Mishra, R. Mongre, Nitin Kumar, 2014, Neuroscience Letters.

Progress and development of C-3, C-6, and N-9 position substituted carbazole integrated molecular hybrid molecules as potential anticancer agents.

Nitin Kumar, P. Luthra, 2021, Mini reviews in medicinal chemistry.

Synthesis, biological evaluation and molecular docking study of novel piperidine and piperazine derivatives as multi-targeted agents to treat Alzheimer's disease.

M. Tiwari, Vishal Nemaysh, P. Luthra, 2015, Bioorganic & medicinal chemistry.

Efficient entry to diversely functionalized spirooxindoles from isatin and their biological activity

Rakesh Kumar, M. Kidwai, Vishal Nemaysh, 2013, Medicinal Chemistry Research.

One-Pot Synthesis of 3,4-Dihydropyridin-2-one via Michael Addition of in situ–Generated Enaminones

P. Luthra, J. Senthil kumar, N. Kumari, 2013 .

Synthesis of novel 7-imino-2-thioxo-3,7-dihydro-2H-thiazolo [4,5-d] pyrimidine derivatives as adenosine A2A receptor antagonists.

C. B. Mishra, P. Jha, P. Luthra, 2010, Bioorganic & medicinal chemistry letters.

Synthesis of 2‐Oxo/Thioxooctahydroquinazolin‐5‐one Derivatives and Their Evaluation as Anticancer Agents.

Rakesh Kumar, M. Kidwai, D. Bhatnagar, 2011 .

Aqua Mediated Synthesis of 2‐Amino‐6‐benzothiazol‐2‐ylsulfanyl‐chromenes and Its in vitro Study, Explanation of the Structure—Activity Relationships (SARs) as Antibacterial Agent.

S. Singh, M. Kidwai, P. Luthra, 2011 .

Design, synthesis, DNA binding studies and evaluation of anticancer potential of novel substituted biscarbazole derivatives against human glioma U87 MG cell line.

Nitin Kumar, Vishal Nemaysh, P. Luthra, 2020, Bioorganic chemistry.

Antagonism of haloperidol-induced swim impairment in l-dopa and caffeine treated mice: A pre-clinical model to study Parkinson's disease

P. Luthra, R. Raghubir, S. K. Barodia, 2009, Journal of Neuroscience Methods.

Therapeutic uses ofCurcuma longa (turmeric)

R. Chandra, P. Luthra, Rambir Singh, 2001, Indian Journal of Clinical Biochemistry.

Identification and optimization of tyrosine hydroxylase activity in Mucuna pruriens DC. var. utilis

S. Singh, P. Luthra, 2010, Planta.

Prospective of curcumin, a pleiotropic signalling molecule from Curcuma longa in the treatment of Glioblastoma.

P. Luthra, Neetika Lal, 2016, European journal of medicinal chemistry.

Demethoxycurcumin induces Bcl-2 mediated G2/M arrest and apoptosis in human glioma U87 cells.

Rakesh Kumar, P. Luthra, Amresh Prakash, 2009, Biochemical and biophysical research communications.

Prospective of Curcumin, a Pleiotropic Signalling Molecule from Curcuma longa in the Treatment of Glioblastoma

P. Luthra, Neetika Lal, 2016 .

Three-dimensional structure prediction of the interaction of CD34 with the SH3 domain of Crk-L.

Y. Verma, G. Gangenahalli, P. Luthra, 2005, Stem cells and development.

Hematopoietic stem cell antigen CD34: role in adhesion or homing.

Y. Verma, Vimal Singh, G. Gangenahalli, 2006, Stem cells and development.

Proteasome mediated degradation of CDC25C and Cyclin B1 in Demethoxycurcumin treated human glioma U87 MG cells to trigger G2/M cell cycle arrest

Vishal Nemaysh, P. Luthra, Neetika Lal, 2018, Toxicology and applied pharmacology.

Antibacterial activity of Curcuma longa rhizome extract on pathogenic bacteria

M. Bose, R. Chandra, P. Luthra, 2002 .

cDNA-Derived Amino Acid Sequence from Rat Brain A2aR Possesses Conserved Motifs PMNYM of TM 5 Domain, Which May Be Involved in Dimerization of A2aR

Pratibha Mehta Luthra, Amresh Prakash, Sandeep Kumar Barodia, 2007, PRIB.

High-performance liquid chromatography separation of enantiomers of mandelic acid and its analogs on a chiral stationary phase.

R. Aneja, P. Luthra, S. Ahuja, 2009, Chirality.

Novel 8-(furan-2-yl)-3-benzyl thiazolo [5,4-e][1,2,4] triazolo [1,5-c] pyrimidine-2(3H)-thione as selective adenosine A2A receptor antagonist

C. B. Mishra, P. Luthra, Amresh Prakash, 2011, Neuroscience Letters.

Novel insights into multitargeted potential of N′-(4-benzylpiperidin-1-yl)alkylamine derivatives in the management of Alzheimer's disease associated pathogenesis

F. Siraj, V. Saini, M. Tiwari, 2016 .

Demethoxycurcumin mediated targeting of MnSOD leading to activation of apoptotic pathway and inhibition of Akt/NF‐&kgr;B survival signalling in human glioma U87 MG cells

Rakesh Kumar, Vishal Nemaysh, P. Luthra, 2018, Toxicology and applied pharmacology.

Design and synthesis of (4E)-4-(4-substitutedbenzylideneamino)-3-substituted-2,3-dihydro-2-thioxothiazole-5-carbonitrile as novel A2A receptor antagonists.

Nitin Kumar, Chandra Bhushan Mishra, Pratibha Mehta Luthra, 2013, Bioorganic & medicinal chemistry.

Novel 8-(furan-2-yl)-3-substituted thiazolo [5,4-e][1,2,4] triazolo[1,5-c] pyrimidine-2(3H)-thione derivatives as potential adenosine A(2A) receptor antagonists.

C. B. Mishra, P. Luthra, J. Senthil kumar, 2010, Bioorganic & medicinal chemistry.

Neuroprotective effect of IDPU (1-(7-imino-3-propyl-2,3-dihydrothiazolo [4,5-d]pyrimidin-6(7H)-yl)urea) in 6-OHDA induced rodent model of hemiparkinson’s disease

P. Luthra, S. Agrawal, Rita Kumari, 2018, Neuroscience Letters.

In silico study of naphtha [1, 2-d] thiazol-2-amine with adenosine A2A receptor and its role in antagonism of haloperidol-induced motor impairments in mice

C. B. Mishra, P. Luthra, Amresh Prakash, 2009, Neuroscience Letters.

Prospective of curcumin, a pleiotropic signalling molecule from Curcuma longa in the treatment of Glioblastoma.

P. Luthra, Neetika Lal, 2016, European journal of medicinal chemistry.

Post-lesion administration of 7-NI attenuated motor and non-motor deficits in 6-OHDA induced bilaterally lesioned female rat model of Parkinson’s disease

P. Luthra, Rita Kumari, J. Kumar, 2015, Neuroscience Letters.

A2AR antagonists triggered the AMPK/m-TOR autophagic pathway to reverse the calcium-dependent cell damage in 6-OHDA induced model of PD

P. Luthra, Tuithung Sophronea, N. Kumari, 2024, Neurochemistry International.

Efficient entry to diversely functionalized spirooxindoles from isatin and their biological activity

Rakesh Kumar, M. Kidwai, Vishal Nemaysh, 2013, Medicinal Chemistry Research.