Neil R. Norcross

发表

Identification of Inhibitors of the Leishmania cdc2-Related Protein Kinase CRK3

Ian H Gilbert, Paul G Wyatt, Torsten Luksch, 2011, ChemMedChem.

Discovery of a Novel Class of Orally Active Trypanocidal N-Myristoyltransferase Inhibitors

Ian H. Gilbert, Irene Hallyburton, Alan H. Fairlamb, 2011, Journal of medicinal chemistry.

A novel multiple-stage antimalarial agent that inhibits protein synthesis

David W. Gray, E. Winzeler, S. Meister, 2015, Nature.

High Throughput Phenotypic Screening of The Human Spermatozoon.

J. Swedlow, I. Gilbert, Neil R. Norcross, 2021, Reproduction.

Male contraceptive development: A medicinal chemistry perspective.

J. Swedlow, K. Read, I. Gilbert, 2022, European journal of medicinal chemistry.

Substituted 2-phenylimidazopyridines: a new class of drug leads for human African trypanosomiasis.

F. Supek, M. Gelb, F. Buckner, 2014, Journal of medicinal chemistry.

Dialkylimidazole inhibitors of Trypanosoma cruzi sterol 14α-demethylase as anti-Chagas disease agents.

M. Gelb, F. Buckner, C. Verlinde, 2013, Bioorganic & medicinal chemistry letters.

A Practical Synthesis of (±)-α-Isosparteine from a Tetraoxobispidine Core†

C. Kilner, Neil R. Norcross, P. R. Blakemore, 2005 .

Lysyl-tRNA synthetase as a drug target in malaria and cryptosporidiosis

Juan A. Bueren-Calabuig, Andrei V. Pisliakov, David W. Gray, 2019, Proceedings of the National Academy of Sciences.

Discovery of a Quinoline-4-carboxamide Derivative with a Novel Mechanism of Action, Multistage Antimalarial Activity, and Potent in Vivo Efficacy

David W. Gray, E. Winzeler, S. Meister, 2016, Journal of medicinal chemistry.

Trisubstituted Pyrimidines as Efficacious and Fast-Acting Antimalarials

E. Winzeler, S. Meister, S. Norval, 2016, Journal of medicinal chemistry.

Total synthesis of (+/-)-alpha-isosparteine, (+/-)-beta-isosparteine, and (+/-)-sparteine from a common tetraoxobispidine intermediate.

L. Zakharov, S. Warriner, M. Sephton, 2008, The Journal of organic chemistry.

A Stereocontrolled Synthesis of (.+-.)--Isosparteine.

S. Warriner, Neil R. Norcross, P. R. Blakemore, 2006 .

Discovery of Inhibitors of Trypanosoma brucei by Phenotypic Screening of a Focused Protein Kinase Library

David W. Gray, S. Norval, L. Stojanovski, 2015, ChemMedChem.

Lead Optimization of a Pyrazole Sulfonamide Series of Trypanosoma bruceiN-Myristoyltransferase Inhibitors: Identification and Evaluation of CNS Penetrant Compounds as Potential Treatments for Stage 2 Human African Trypanosomiasis

Stuart P. McElroy, S. Norval, Frederick R. C. Simeons, 2014, Journal of medicinal chemistry.

Validation of N-myristoyltransferase as Potential Chemotherapeutic Target in Mammal-Dwelling Stages of Trypanosoma cruzi

I. Gilbert, I. C. Almeida, Armando Varela-Ramírez, 2016, PLoS neglected tropical diseases.

Compounds enhancing human sperm motility identified using a high-throughput phenotypic screening platform

J. Swedlow, K. Read, I. Gilbert, 2021, bioRxiv.

Sperm Toolbox – A selection of small molecules to study human spermatozoa

J. Swedlow, K. Read, I. Gilbert, 2023, bioRxiv.

Lead optimization of a pyrazole sulfonamide series of trypanosoma brucei N myristoyltransferase inhibitors

Stuart P. McElroy, S. Norval, Frederick R. C. Simeons, 2014 .

Corrigendum: A novel multiple-stage antimalarial agent that inhibits protein synthesis

E. Winzeler, S. Meister, J. Rayner, 2016, Nature.

Exploring the Trypanosoma brucei Hsp83 Potential as a Target for Structure Guided Drug Design

I. Gilbert, M. Ferguson, A. Wernimont, 2013, PLoS neglected tropical diseases.

Sperm Toolbox – A selection of small molecules to study human spermatozoa

J. Swedlow, K. Read, I. Gilbert, 2023, bioRxiv.