M. Gao

发表

X‐Ray Crystal Structure of Bone Marrow Kinase in the X Chromosome: A Tec Family Kinase

D. Xie, J. Sack, Chiehying Y Chang, 2011, Chemical biology & drug design.

Insights into Vitamin D metabolism using cyp24 over-expression and knockout systems in conjunction with liquid chromatography/mass spectrometry (LC/MS)

Glenville Jones, R. St-Arnaud, M. Gao, 2004, The Journal of Steroid Biochemistry and Molecular Biology.

Multidrug Resistance Protein

S. Cole, D. W. Loe, C. Grant, 1998, The Journal of Biological Chemistry.

Biologic-like In Vivo Efficacy with Small Molecule Inhibitors of TNFα Identified Using Scaffold Hopping and Structure-Based Drug Design Approaches.

D. Shuster, J. Macor, J. Yanchunas, 2020, Journal of medicinal chemistry.

Pharmacologic Profile of the Adnectin BMS-962476, a Small Protein Biologic Alternative to PCSK9 Antibodies for LDL Lowering

R. Parker, M. Witmer, Gerald, 2014 .

Characterization of Binding of Leukotriene C4 by Human Multidrug Resistance Protein 1

S. Cole, W. Qiu, R. Deeley, 2001, The Journal of Biological Chemistry.

Epitope mapping of monoclonal antibodies specific for the 190-kDa multidrug resistance protein (MRP).

D. Hipfner, S. Cole, G. Scheffer, 1998, British Journal of Cancer.

Crystal structure of microtubule affinity-regulating kinase 4 catalytic domain in complex with a pyrazolopyrimidine inhibitor.

J. Sack, Chunhong Yan, S. E. Kiefer, 2015, Acta crystallographica. Section F, Structural biology communications.

Cloning, purification, crystallization and preliminary X-ray analysis of the catalytic domain of human receptor-like protein tyrosine phosphatase γ in three different crystal forms.

V. Goldfarb, W. Metzler, K. Kish, 2011, Acta crystallographica. Section F, Structural biology and crystallization communications.

High-throughput high-content imaging assays for identification and characterization of selective AXL pathway inhibitors.

K. Constantine, D. Shen, M. Witmer, 2014, Assay and drug development technologies.

Biotechnology Based Process for Production of a Disulfide-Bridged Peptide.

Steven H. Chan, Olav K. Lyngberg, M. Witmer, 2016, Bioconjugate chemistry.

Role of Carboxylate Residues Adjacent to the Conserved Core Walker B Motifs in the Catalytic Cycle of Multidrug Resistance Protein 1 (ABCC1)*

S. Cole, L. Payen, R. Deeley, 2003, Journal of Biological Chemistry.

Functional Interactions Between Nucleotide Binding Domains and Leukotriene C4 Binding Sites of Multidrug Resistance Protein 1 (ABCC1)

S. Cole, L. Payen, R. Deeley, 2005, Molecular Pharmacology.

Identification of the structural and functional boundaries of the multidrug resistance protein 1 cytoplasmic loop 3.

S. Cole, R. Deeley, C. Westlake, 2003, Biochemistry.

Discovery and preclinical characterization of the cyclopropylindolobenzazepine BMS-791325, a potent allosteric inhibitor of the hepatitis C virus NS5B polymerase.

Chong-Hwan Chang, M. Witmer, B. Beno, 2014, Journal of medicinal chemistry.

Structural Determinants of Substrate Specificity Differences between Human Multidrug Resistance Protein (MRP) 1 (ABCC1) and MRP3 (ABCC3)

S. Cole, M. DeGorter, C. Grant, 2008, Drug Metabolism and Disposition.

Genome-scale protein expression and structural biology of Plasmodium falciparum and related Apicomplexan organisms.

Alexey Bochkarev, Wolfram Tempel, Anne Mulichak, 2007, Molecular and biochemical parasitology.

Multiple and single binding modes of fragment-like kinase inhibitors revealed by molecular modeling, residue type-selective protonation, and nuclear overhauser effects.

Wayne Vaccaro, Luciano Mueller, K. Constantine, 2008, Journal of medicinal chemistry.

Reconstitution of ATP-dependent Leukotriene C4 Transport by Co-expression of Both Half-molecules of Human Multidrug Resistance Protein in Insect Cells*

S. Cole, D. W. Loe, C. Grant, 1996, The Journal of Biological Chemistry.

Developing Adnectins that target SRC co-activator binding to PXR: a structural approach toward understanding promiscuity of PXR.

Eric T Baldwin, Martin C. Wright, Andrew J Tebben, 2015, Journal of molecular biology.

An improved protocol for amino acid type-selective isotope labeling in insect cells

L. Mueller, M. Witmer, D. Hedin, 2017, Journal of Biomolecular NMR.

Structural Determinants of Substrate Specificity Differences between Human Multidrug Resistance Protein (MRP) 1 (ABCC1) and MRP3 (ABCC3)

S. Cole, M. DeGorter, C. Grant, 2008 .

Comparison of the Functional Characteristics of the Nucleotide Binding Domains of Multidrug Resistance Protein 1*

S. Cole, D. W. Loe, C. Grant, 2000, The Journal of Biological Chemistry.

Stable complex formation between HIV Rev and the nucleosome assembly protein, NAP1, affects Rev function.

C. Burks, D. Richards, Veronica Canadien, 2009, Virology.

Discovery of BMS-986339, a Pharmacologically Differentiated Farnesoid X Receptor Agonist for the Treatment of Nonalcoholic Steatohepatitis.

S. E. Kiefer, J. Krupinski, Srinivas Cheruku, 2022, Journal of medicinal chemistry.

Identification and Characterization of Functionally Important Elements in the Multidrug Resistance Protein 1 COOH-terminal Region*

S. Cole, L. Payen, R. Deeley, 2004, Journal of Biological Chemistry.

Monoclonal Antibodies That Inhibit the Transport Function of the 190-kDa Multidrug Resistance Protein, MRP

D. Hipfner, S. Cole, W. Qiu, 1999, The Journal of Biological Chemistry.

Small molecule receptor protein tyrosine phosphatase γ (RPTPγ) ligands that inhibit phosphatase activity via perturbation of the tryptophan-proline-aspartate (WPD) loop.

V. Goldfarb, B. Beno, J. Macor, 2011, Journal of medicinal chemistry.

Crystal structures of apo and inhibitor-bound TGFβR2 kinase domain: insights into TGFβR isoform selectivity.

D. Xie, S. Sheriff, Chunhong Yan, 2016, Acta crystallographica. Section D, Structural biology.

A Functional NaV1.7-NaVAb Chimera with a Reconstituted High-Affinity ProTx-II Binding Site

D. Langley, J. Herrington, M. Ahlijanian, 2017, Molecular Pharmacology.

Pharmacologic Profile of the Adnectin BMS-962476, a Small Protein Biologic Alternative to PCSK9 Antibodies for Low-Density Lipoprotein Lowering

Doree Sitkoff, Daniel Meyers, R. Parker, 2014, The Journal of Pharmacology and Experimental Therapeutics.

Characterization of Mauritian Cynomolgus Macaque FcγR Alleles Using Long-Read Sequencing

Trent M. Prall, Hailey E. Bussan, A. Yamniuk, 2018, The Journal of Immunology.

Using yeast surface display to engineer a soluble and crystallizable construct of hematopoietic progenitor kinase 1 (HPK1).

D. Xie, S. Sheriff, D. Lipovšek, 2020, Acta crystallographica. Section F, Structural biology communications.

Importance of cytochrome P450-mediated metabolism in the mechanism of action of vitamin D analogs.

Glenville Jones, M. Gao, S. Masuda, 2003, Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer.

Structure-based amelioration of PXR transactivation in a novel series of macrocyclic allosteric inhibitors of HIV-1 integrase.

Stephen R. Johnson, N. Meanwell, D. Langley, 2020, Bioorganic & medicinal chemistry letters.

An improved protocol for amino acid type-selective isotope labeling in insect cells

M. Witmer, D. Hedin, W. Metzler, 2017, Journal of Biomolecular NMR.

Crystal structure of microtubule affinity-regulating kinase 4 catalytic domain in complex with a pyrazolopyrimidine inhibitor.

J. Sack, Chunhong Yan, S. E. Kiefer, 2015, Acta crystallographica. Section F, Structural biology communications.

Multidrug Resistance Protein

S. Cole, D. W. Loe, C. Grant, 1998, The Journal of Biological Chemistry.

A Functional NaV1.7-NaVAb Chimera with a Reconstituted High-Affinity ProTx-II Binding Site

D. Langley, J. Herrington, M. Ahlijanian, 2017, Molecular Pharmacology.

The structure of human tau-tubulin kinase 1 both in the apo form and in complex with an inhibitor.

A. Cacace, D. Xie, Yaqun Zhang, 2014, Acta crystallographica. Section F, Structural biology communications.

Dual universal peptide approach to bioanalysis of human monoclonal antibody protein drug candidates in animal studies.

M. Jemal, A. Tymiak, M. Furlong, 2013, Bioanalysis.

Biotechnology Based Process for Production of a Disulfide-Bridged Peptide.

M. Witmer, R. Hanson, J. Bryson, 2016, Bioconjugate chemistry.

X‐Ray Crystal Structure of Bone Marrow Kinase in the X Chromosome: A Tec Family Kinase

D. Xie, J. Sack, Chiehying Y Chang, 2011, Chemical biology & drug design.

Expression profiling of herpesvirus and vaccinia virus proteins using a high-throughput baculovirus screening system.

C. Burks, B. Beattie, G. McFadden, 2005, Journal of proteome research.