P. Moreau

发表

In-vitro antiproliferative activities and kinase inhibitory potencies of meridianin derivatives

D. Fabbro, M. Prudhomme, E. Débiton, 2008, Anti-cancer drugs.

Synthesis of aminopyrimidylindoles structurally related to meridianins

M. Prudhomme, A. Youssef, Emilie Rossignol, 2007 .

Synthesis of glycosyl-isoindigo derivatives

M. Prudhomme, E. Saab, P. Moreau, 2004 .

Synthesis and activities of new indolopyrrolobenzodiazepine derivatives toward acute myeloid leukemia cells.

S. Døskeland, L. Herfindal, Ronja Bjørnstad, 2015, Bioorganic & medicinal chemistry.

Synthesis and antiproliferative activities of isoindigo and azaisoindigo derivatives.

P. Moreau, F. Anizon, Fadoua Bouchikhi, 2008, European journal of medicinal chemistry.

Synthesis and antiproliferative activities of diversely substituted glycosyl-isoindigo derivatives.

M. Prudhomme, E. Débiton, C. Barthomeuf, 2006, European journal of medicinal chemistry.

Recent Advances in Pain Management: Relevant Protein Kinases and Their Inhibitors

P. Moreau, F. Anizon, F. Giraud, 2021, Molecules.

Pim-selective inhibitor DHPCC-9 reveals Pim kinases as potent stimulators of cancer cell migration and invasion

S. Virtanen, M. Prudhomme, P. Koskinen, 2010, Molecular Cancer.

Synthesis and biological activities of new pyrrolocarbazole-imidazobenzimidazole conjugates

A. Shtil, P. Moreau, F. Anizon, 2020 .

Synthesis and Applications of Dihydropyrrolocarbazoles

P. Moreau, F. Anizon, F. Giraud, 2019, European Journal of Organic Chemistry.

Pim Kinases Promote Migration and Metastatic Growth of Prostate Cancer Xenografts

I. Paatero, P. Koskinen, P. Härkönen, 2015, PloS one.

Use of copper(I) catalyzed azide alkyne cycloaddition (CuAAC) for the preparation of conjugated pyrrolo[2,3-a]carbazole Pim kinase inhibitors.

A. Gautier, M. El-ghozzi, P. Koskinen, 2012, European journal of medicinal chemistry.

Kinase inhibitory potencies and in vitro antiproliferative activities of N-10 substituted pyrrolo[2,3-a]carbazole derivatives.

E. Débiton, P. Moreau, F. Anizon, 2012, Bioorganic & medicinal chemistry letters.

Synthesis and preliminary in vitro kinase inhibition evaluation of new diversely substituted pyrido[3,4-g]quinazoline derivatives.

L. Meijer, N. Loaëc, P. Moreau, 2016, Bioorganic & medicinal chemistry letters.

Kinase inhibitions in pyrido[4,3-h] and [3,4-g]quinazolines: Synthesis, SAR and molecular modeling studies.

B. Baratte, S. Ruchaud, B. Josselin, 2019, Bioorganic & medicinal chemistry.

Semi-synthesis, topoisomerase I and kinases inhibitory properties, and antiproliferative activities of new rebeccamycin derivatives.

C. Bailly, P. Renard, B. Pfeiffer, 2003, Bioorganic & medicinal chemistry.

Analogues of antifungal tjipanazoles from rebeccamycin.

C. Bailly, M. Sancelme, P. Renard, 2004, Bioorganic & medicinal chemistry.

Rebeccamycin Derivatives as Dual DNA-Damaging Agents and Potent Checkpoint Kinase 1 Inhibitors

L. Meijer, P. Peixoto, B. Pfeiffer, 2008, Molecular Pharmacology.

Syntheses, biochemical and biological evaluation of staurosporine analogues from the microbial metabolite rebeccamycin.

D. Fabbro, C. Bailly, M. Sancelme, 1998, Bioorganic & medicinal chemistry.

Synthesis and antiproliferative evaluation of glucosylated pyrazole analogs of K252c

A. Shtil, P. Moreau, F. Anizon, 2018 .

Alternative RNA splicing modulates ribosomal composition and determines the spatial phenotype of glioblastoma cells

Michael C. Condro, I. Nakano, O. Dontsova, 2022, Nature Cell Biology.

Synthesis and biological activities of pyrazolo[3,4-g]quinoxaline derivatives.

E. Débiton, P. Moreau, F. Anizon, 2010, European journal of medicinal chemistry.

Synthesis and Fluorescent Properties of New Heterobifunctional Fluorescent Probes

T. Besson, B. Joseph, P. Moreau, 1992 .

Synthesis of 1,6-dihydropyrrolo[2,3-g]indazoles using Larock indole annulation

P. Moreau, F. Anizon, Laurent Gavara, 2011 .

New N-1,N-10-bridged pyrrolo[2,3-a]carbazole-3-carbaldehydes: synthesis and biological activities.

S. Døskeland, L. Herfindal, P. Moreau, 2014, Bioorganic chemistry.

Regioselective synthesis of novel substituted indazole-5,6-diamine derivatives

P. Moreau, F. Anizon, Laurent Gavara, 2011 .

Bicyclic 6-6 Systems: Other Four Heteroatoms 2/2

P. Moreau, F. Anizon, 2020 .

Synthesis and molecular modeling study of new trimeric quinoline derivatives.

P. Moreau, F. Anizon, V. Théry, 2011, Bioorganic chemistry.

Synthesis and in vitro antiproliferative activities of quinoline derivatives.

P. Moreau, F. Anizon, B. Aboab, 2010, European journal of medicinal chemistry.

Synthesis and biological evaluation of oxindoles and benzimidazolinones derivatives.

M. Sancelme, M. Prudhomme, S. Messaoudi, 2004, European journal of medicinal chemistry.

Synthesis and biological evaluation of diversely substituted indolin-2-ones.

D. Fabbro, M. Sancelme, M. Prudhomme, 2008, European journal of medicinal chemistry.

Synthesis and biological activities of polyquinoline derivatives: new Bcl-2 family protein modulators.

N. Bonnefoy, P. Moreau, F. Anizon, 2012, European journal of medicinal chemistry.

Synthesis and biological activities of new di- and trimeric quinoline derivatives.

Marie‐Laure Fogeron, P. Moreau, F. Anizon, 2010, Bioorganic & medicinal chemistry.

First Synthesis of 3,6′- and 3,7′-Biquinoline Derivatives

P. Moreau, F. Anizon, Sidonie Broch, 2008 .

In-vitro antiproliferative activities and kinase inhibitory potencies of glycosyl-isoindigo derivatives

D. Fabbro, M. Prudhomme, P. Moreau, 2007, Anti-cancer drugs.

Synthesis and antiproliferative activities of indolin-2-one derivatives bearing amino acid moieties.

M. Prudhomme, E. Débiton, P. Moreau, 2006, European journal of medicinal chemistry.

Identification of pyrrolo[2,3-g]indazoles as new Pim kinase inhibitors.

P. Moreau, F. Anizon, V. Théry, 2013, Bioorganic & medicinal chemistry letters.

Stereoselective addition reactions to chiral N-benzylidene-p-toluenesulfinamides. Application to the synthesis of optically active 1,2-diphenylethylamines

P. Moreau, J. Mérour, D. Bouzard, 1997 .

From benzofuro-, benzothieno- and 10-methylindolo-[2,3-b]-fused benzothiopyrano[4,3,2-de]quinolines to the corresponding benzothiopyrano[4,3,2-de]1,8-naphthyridines: synthesis and properties of these hexacyclic heteroaromatic compounds

T. Roisnel, W. Erb, O. Mongin, 2023, New Journal of Chemistry.

Synthesis and biological activities of indolocarbazoles bearing amino acid residues.

C. Bailly, M. Sancelme, B. Pfeiffer, 2001, European journal of medicinal chemistry.

Rebeccamycin analogues bearing amine substituents or other groups on the sugar moiety.

C. Bailly, M. Sancelme, M. Prudhomme, 2003, Bioorganic & medicinal chemistry.

A Convenient Synthesis of Diversely Substituted N,N-Dimethyl-4-oxo-2-(E)-alkenamides

G. Guillaumet, P. Moreau, G. Coudert, 1994 .

Synthesis and biological activity of pyrazole analogues of the staurosporine aglycon K252c.

A. Shtil, P. Moreau, F. Anizon, 2016, Bioorganic & medicinal chemistry.

Synthesis, kinase inhibitory potencies, and in vitro antiproliferative evaluation of new Pim kinase inhibitors.

Stefan Knapp, Panagis Filippakopoulos, Jenny Bain, 2009, Journal of medicinal chemistry.

Synthesis and Antiproliferative Activities of Indolin‐2‐one Derivatives Bearing Amino Acid Moieties.

M. Prudhomme, E. Débiton, P. Moreau, 2006 .

Recognition and cleavage of DNA by rebeccamycin- or benzopyridoquinoxaline conjugated of triple helix-forming oligonucleotides.

C. Bailly, M. Prudhomme, P. Arimondo, 2000, Bioorganic & medicinal chemistry.

Discovery of pyrido[3,4-g]quinazoline derivatives as CMGC family protein kinase inhibitors: Design, synthesis, inhibitory potency and X-ray co-crystal structure.

L. Meijer, S. Knapp, A. Chaikuad, 2016, European journal of medicinal chemistry.

ChemInform Abstract: Enantioselective C-C Bond Formation with Heterogenized Catalysts

D. Brunel, N. Bellocq, S. Abramson, 2007 .

A Kinase Inhibitor with Anti-Pim Kinase Activity is a Potent and Selective Cytotoxic Agent Toward Acute Myeloid Leukemia

Ø. Bruserud, S. Døskeland, A. Brenner, 2019, Molecular Cancer Therapeutics.

Synthesis and Biological Activities of 4‐Substituted Pyrrolo[2,3‐a]carbazole Pim Kinase Inhibitors.

E. Débiton, P. Moreau, F. Anizon, 2013 .

Functionalization of 9-thioxanthone at the 1-position: From arylamino derivatives to [1]benzo(thio)pyrano[4,3,2-de]benzothieno[2,3-b]quinolines of biological interest.

B. Baratte, V. Dorcet, R. Duval, 2019, Bioorganic chemistry.

Synthesis of pyrazolo[4,3-a]phenanthridines, a new scaffold for Pim kinase inhibition.

P. Moreau, F. Anizon, V. Théry, 2014, Bioorganic & medicinal chemistry.

Synthesis and biological activities of aminopyrimidyl-indoles structurally related to meridianins.

L. Meijer, M. Prudhomme, E. Débiton, 2009, Bioorganic & medicinal chemistry.

Synthesis, kinase inhibitory potencies and in vitro antiproliferative activity of isoindigo and 7'-azaisoindigo derivatives substituted by Sonogashira cross-coupling.

P. Moreau, F. Anizon, Fadoua Bouchikhi, 2009, European journal of medicinal chemistry.

Synthesis of 1,3-dienes bearing both electron-donor and acceptor substituents

G. Guillaumet, P. Moreau, G. Coudert, 1991 .

Synthesis of Diaryl Ethers with Different Functionalities.

G. Guillaumet, P. Moreau, G. Coudert, 1994 .

Synthesis, protein kinase inhibitory potencies, and in vitro antiproliferative activities of meridianin derivatives.

L. Meijer, O. Lozach, E. Débiton, 2011, Journal of medicinal chemistry.

New pyrido[3,4-g]quinazoline derivatives as CLK1 and DYRK1A inhibitors: synthesis, biological evaluation and binding mode analysis.

S. Knapp, A. Joerger, B. Baratte, 2019, European journal of medicinal chemistry.

Synthesis, Pim kinase inhibitory potencies and in vitro antiproliferative activities of diversely substituted pyrrolo[2,3-a]carbazoles.

P. Cohen, J. Bain, P. Moreau, 2010, Bioorganic & Medicinal Chemistry.

Pyridin-2(1H)one derivatives: A possible new class of therapeutics for mechanical allodynia.

A. Artola, Isabelle Abrunhosa-Thomas, R. Dallel, 2019, European journal of medicinal chemistry.

Fighting tumor cell survival: advances in the design and evaluation of Pim inhibitors.

V. Danilenko, A. Shtil, P. Moreau, 2010, Current medicinal chemistry.

Syntheses and biological activities (topoisomerase inhibition and antitumor and antimicrobial properties) of rebeccamycin analogues bearing modified sugar moieties and substituted on the imide nitrogen with a methyl group.

D. Fabbro, C. Bailly, M. Sancelme, 1997, Journal of medicinal chemistry.

Identification of 1,6-dihydropyrazolo[4,3-c]carbazoles and 3,6-dihydropyrazolo[3,4-c]carbazoles as new Pim kinase inhibitors.

P. Moreau, F. Anizon, V. Théry, 2013, Bioorganic & medicinal chemistry.

Synthesis and biological activities of 4-substituted pyrrolo[2,3-a]carbazole Pim kinase inhibitors.

E. Débiton, P. Moreau, F. Anizon, 2012, European journal of medicinal chemistry.

Cytotoxicities of three rebeccamycin derivatives in the National Cancer Institute screening of 60 human tumor cell lines

E. Sausville, S. Holbeck, M. Prudhomme, 2005, Anti-cancer drugs.

Syntheses and antiproliferative activities of new rebeccamycin derivatives with the sugar unit linked to both indole nitrogens.

P. Renard, B. Pfeiffer, M. Prudhomme, 2002, Journal of medicinal chemistry.

Synthesis and biological evaluation of Haspin inhibitors: Kinase inhibitory potency and cellular activity.

S. Knapp, A. Chaikuad, B. Baratte, 2022, European journal of medicinal chemistry.

Synthesis of the Bifunctional Chelating Agent 6-(4-Aminobenzyl)-1,4,8,11-tetra-azacyclotetradecan-N,N',N'',N'''-tetraacetic Acid (H2NBn-TETA)

V. Snieckus, E. Griffen, P. Moreau, 1997 .

Synthesis and Kinase Inhibitory Potencies of Pyrazolo[3,4-g]isoquinolines

S. Ruchaud, B. Josselin, P. Moreau, 2022, Molecules.