R. Riley

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Tristetraprolin, a Negative Regulator of mRNA Stability, Is Increased in Old B Cells and Is Involved in the Degradation of E47 mRNA1

P. Blackshear, B. Blomberg, D. Frasca, 2007, The Journal of Immunology.

Neonatal Immune Response

R. Riley, 1998 .

A Molecular Mechanism for TNF-α–Mediated Downregulation of B Cell Responses

A. Díaz, B. Blomberg, D. Frasca, 2012, The Journal of Immunology.

Decreased E12 and/or E47 Transcription Factor Activity in the Bone Marrow As Well As in the Spleen of Aged Mice1

B. Blomberg, D. Frasca, D. Nguyen, 2003, The Journal of Immunology.

NK cells in the CD19− B220+ bone marrow fraction are increased in senescence and reduce E2A and surrogate light chain proteins in B cell precursors

B. Blomberg, P. Keating, R. Riley, 2009, Mechanisms of Ageing and Development.

Oxidation of N-alkyl amides to novel hydroperoxides by dioxygen

R. Riley, R. Drago, 1990 .

Transcription Factors in Mature B Cells During Aging

B. Blomberg, D. Frasca, R. Riley, 2019, Handbook of Immunosenescence.

Transcription Factors in Mature B-Cells During Aging

B. Blomberg, D. Frasca, R. Riley, 2009 .

Cells in Aged Mice and Humans Mechanisms for Decreased Function of B

B. Blomberg, D. Frasca, A. Landin, 2008 .

Mechanisms for Decreased Function of B Cells in Aged Mice and Humans1

B. Blomberg, D. Frasca, A. Landin, 2008, The Journal of Immunology.

mRNAand Is Involved in the Degradation of E47 mRNA Stability, Is Increased in Old B Cells Tristetraprolin, a Negative Regulator of

P. Blackshear, B. Blomberg, D. Frasca, 2007 .

Effect of age on the immunoglobulin class switch.

B. Blomberg, D. Frasca, R. Riley, 2004, Critical reviews in immunology.

Electron-Transfer Reactions of Ruthenium Trisbipyridyl-Viologen Donor-Acceptor Molecules: Comparison of the Distance Dependence of Electron Transfer-Rates in the Normal and Marcus Inverted Regions

T. Mallouk, G. Saupe, R. Schmehl, 1994 .

A phenotypically distinct subset of immature B cells exhibits partial activation, increased survival, and preferential expression of VhS107

R. Riley, A. King, E. Wilson, 2003, European journal of immunology.

Humoral immune response and B-cell functions including immunoglobulin class switch are downregulated in aged mice and humans.

B. Blomberg, D. Frasca, R. Riley, 2005, Seminars in immunology.

Graft-versus-host-disease-associated lymphoid hypoplasia and B cell dysfunction is dependent upon donor T cell-mediated Fas-ligand function, but not perforin function.

E. Podack, R. Levy, R. Riley, 1997, Proceedings of the National Academy of Sciences of the United States of America.

Detection of low avidity anti-DNA antibodies in systemic lupus erythematosus.

H. Mcgrath, R. Riley, R. Taylor, 1979, Arthritis and rheumatism.

Decreased E47 in Senescent B Cell Precursors Is Stage Specific and Regulated Posttranslationally by Protein Turnover1

B. Blomberg, D. Frasca, R. Riley, 2004, The Journal of Immunology.

Posttranslationally by Protein Turnover Is Stage Specific and Regulated Decreased E47 in Senescent B Cell Precursors

B. Blomberg, D. Frasca, R. Riley, 2004 .

Levels of E2A protein expression in B cell precursors are stage-dependent and inhibited by stem cell factor (c-kit ligand).

R. Riley, A. King, Jennean Knowles, 2002, Experimental hematology.

In senescence, age‐associated B cells secrete TNFα and inhibit survival of B‐cell precursors *

B. Blomberg, D. Frasca, R. Riley, 2013, Aging cell.

Old mice retain bone marrow B1 progenitors, but lose B2 precursors, and exhibit altered immature B cell phenotype and light chain usage

B. Blomberg, R. Riley, S. Alter-Wolf, 2009, Mechanisms of Ageing and Development.

Impaired B lymphopoiesis in old age: a role for inflammatory B cells?

R. Riley, 2013, Immunologic Research.

B. Blomberg, D. Frasca, R. Riley, 2004, Experimental Gerontology.

Deficient B lymphopoiesis in murine senescence: potential roles for dysregulation of E2A, Pax-5, and STAT5.

B. Blomberg, D. Frasca, R. Riley, 2005, Seminars in immunology.

Effects of interleukin 4 on neonatal B lymphocyte tolerance.

R. Riley, J. Peacock, V. Pinto, 1989, Biochemical and biophysical research communications.

Protein phosphatase 2A (PP2A) is increased in old murine B cells and mediates p38 MAPK/tristetraprolin dephosphorylation and E47 mRNA instability

A. Díaz, B. Blomberg, D. Frasca, 2010, Mechanisms of Ageing and Development.

Deaminase, and Ig Class Switch in Human B Factor E2A, Activation-Induced Cytidine Aging Down-Regulates the Transcription

J. G. Ryan, B. Blomberg, D. Frasca, 2013 .

Cells Deaminase , and Ig Class Switch in Human B Factor E 2 A , Activation-Induced Cytidine Aging Down-Regulates the Transcription

J. G. Ryan, B. Blomberg, D. Frasca, 2008 .

B cell precursors in senescent mice exhibit decreased recruitment into proliferative compartments and altered expression of Bcl-2 family members

Wei Xu, R. Riley, E. Sherwood, 2003, Mechanisms of Ageing and Development.

Transgenic Human λ5 Rescues the Murine λ5 Nullizygous Phenotype1

H. Jäck, G. Beck-Engeser, B. Blomberg, 2000, The Journal of Immunology.

Aged mice exhibit distinct B cell precursor phenotypes differing in activation, proliferation and apoptosis

B. Blomberg, R. Riley, E. Sherwood, 2003, Experimental Gerontology.

The reduced expression of surrogate light chains in B cell precursors from senescent BALB/c mice is associated with decreased E2A proteins

B. Blomberg, Wei Xu, R. Riley, 2000, Mechanisms of Ageing and Development.

The Specificity Repertoire of Prereceptor and Mature B Cells a

D. Wylie, M. Stone, D. Zharhary, 1983, Annals of the New York Academy of Sciences.

Suppression of B-cell development as a result of selective expansion of donor T cells during the minor H antigen graft-versus-host reaction.

B. Garvy, B. Hamilton, R. Riley, 1993, Blood.

Bone marrow stromal cells modulate both kappa light chain and Ly1 antigen expression on Ly1+ pre-B cell lines in vitro

R. Riley, J. Elia, M. G. Kruger, 1990 .

A kinetic study of sulfide oxidation by sodium hypochlorite using phase-transfer catalysis

R. Riley, R. Drago, J. Ramsden, 1989 .

Photoinduced Electron Transfer in Covalently Linked Ruthenium Tris(bipyridyl)-Viologen Molecules: Observation of Back Electron Transfer in the Marcus Inverted Region

T. Mallouk, R. Schmehl, S. Atherton, 1992 .

Effects of fenbendazole on the murine humoral immune system.

B. Blomberg, D. Frasca, A. Landin, 2009, Journal of the American Association for Laboratory Animal Science : JAALAS.

SDS induced conformational changes in the combining site of anti-trinitrophenyl antibodies. A kinetic study.

R. Riley, R. Taylor, D. H. Shaffner, 1977, Immunochemistry.

Autoantibodies to T-lineage cells in aged mice

B. Adkins, R. Riley, 1998, Mechanisms of Ageing and Development.

Inflammatory immune cells may impair the preBCR checkpoint, reduce new B cell production, and alter the antibody repertoire in old age

B. Blomberg, R. Riley, K. Khomtchouk, 2018, Experimental Gerontology.

Age-associated B cells (ABC) inhibit B lymphopoiesis and alter antibody repertoires in old age.

B. Blomberg, R. Riley, K. Khomtchouk, 2017, Cellular immunology.

In old BALB/c mice, bone marrow pre-B cell and surrogate light chain reduction is associated with increased B cell reactivity to phosphorylcholine, but reduced T15 idiotype dominance

B. Blomberg, R. Riley, K. Khomtchouk, 2017, Mechanisms of Ageing and Development.

In aged mice, low surrogate light chain promotes pro-B-cell apoptotic resistance, compromises the PreBCR checkpoint, and favors generation of autoreactive, phosphorylcholine-specific B cells

B. Blomberg, D. Frasca, W. Khan, 2015, Aging cell.

Aging murine B cells have decreased class switch induced by anti-CD40 or BAFF

B. Blomberg, D. Frasca, R. Riley, 2007, Experimental Gerontology.

B cells, E2A, and aging

B. Blomberg, D. Frasca, R. Riley, 2005, Immunological reviews.

Pre-B cell loss in senescence coincides with preferential development of immature B cells characterized by partial activation and altered Vh repertoire

R. Riley, A. King, E. Wilson, 2005, Experimental Gerontology.

Effects of aging on proliferation and E47 transcription factor activity induced by different stimuli in murine splenic B cells

B. Blomberg, D. Frasca, D. Nguyen, 2003, Mechanisms of Ageing and Development.

B cells and aging: molecules and mechanisms.

Yi Hao, B. Blomberg, D. Frasca, 2009, Trends in immunology.

Transgenic Human l5 Rescues the Murinel5 Nullizygous Phenotype

H. Jäck, G. Beck-Engeser, B. Blomberg, 2000 .

B. Blomberg, D. Frasca, D. Nguyen, 2003, Frontiers in bioscience : a journal and virtual library.

E47 retroviral rescue of intrinsic B‐cell defects in senescent mice

B. Blomberg, D. Frasca, A. Landin, 2011, Aging cell.

Accelerated Notch-Dependent Degradation of E47 Proteins in Aged B Cell Precursors Is Associated with Increased ERK MAPK Activation1

B. Blomberg, R. Riley, A. King, 2007, The Journal of Immunology.

ActivationAssociated with Increased ERK MAPK E47 Proteins in Aged B Cell Precursors Is Accelerated Notch-Dependent Degradation of

B. Blomberg, R. Riley, A. King, 2007 .

Reduced Ig Class Switch in Aged Mice Correlates with Decreased E47 and Activation-Induced Cytidine Deaminase1

B. Blomberg, D. Frasca, R. Riley, 2004, The Journal of Immunology.

Activation-Induced Cytidine Deaminase Correlates with Decreased E 47 and Reduced Ig Class Switch in Aged Mice

B. Blomberg, D. Frasca, R. Riley, 2004 .

B cell precursors are decreased in senescent BALB/c mice, but retain normal mitotic activity in vivo and in vitro.

R. Riley, J. Elia, M. G. Kruger, 1991, Clinical immunology and immunopathology.

Deviation of the B Cell Pathway in Senescent Mice Is Associated with Reduced Surrogate Light Chain Expression and Altered Immature B Cell Generation, Phenotype, and Light Chain Expression1

B. Blomberg, R. Riley, S. Alter-Wolf, 2009, The Journal of Immunology.

Light Chain Expression and Altered Mice Is Associated with Reduced Surrogate Deviation of the B Cell Pathway in Senescent

B. Blomberg, R. Riley, S. Alter-Wolf, 2008 .

B cell repertoire diversification precedes immunoglobulin receptor expression

D. Wylie, R. Riley, N. Klinman, 1983, Journal of Experimental Medicine.

Genetic and Environmental Control of B-Cell Idiotype Expression

D. Zharhary, R. Riley, N. Klinman, 1984 .

Aging Down-Regulates the Transcription Factor E2A, Activation-Induced Cytidine Deaminase, and Ig Class Switch in Human B Cells1

J. G. Ryan, B. Blomberg, D. Frasca, 2008, The Journal of Immunology.

RNA Stability of the E2A-Encoded Transcription Factor E47 Is Lower in Splenic Activated B Cells from Aged Mice1

B. Blomberg, D. Frasca, A. Landin, 2005, The Journal of Immunology.

Activated B Cells from Aged Mice SplenicTranscription Factor E 47 Is Lower in-Encoded E 2 A RNA Stability of the

B. Blomberg, D. Frasca, A. Landin, 2005 .

Treatment of rhesus monkey allograft recipients with a combination of anti-T-cell monoclonal antibodies.

J. Thomas, U. Gross, R. Riley, 1993, Transplantation proceedings.

A comparative review of aging and B cell function in mice and humans.

A. Díaz, D. Frasca, M. Cancro, 2013, Current opinion in immunology.

Effects of aging on DNA-binding activity of the E47 transcription factor in splenic B cells

B. Blomberg, D. Frasca, D. Nguyen, 2004, Mechanisms of Ageing and Development.

Decreased E 12 and / or E 47 Transcription Factor Activity in the Bone Marrow As Well As in the Spleen of Aged Mice 1

B. Blomberg, D. Frasca, D. Nguyen, 2002 .

Abnormal development of B cells and B cell progenitors in autoimmune (NZB x NZW)F1 mice.

R. Riley, M. G. Kruger, E. A. Riley, 1989, Clinical immunology and immunopathology.

Autoantibodies inhibit interleukin-7-mediated proliferation and are associated with the age-dependent loss of pre-B cells in autoimmune New Zealand Black Mice.

B. Garvy, M. Merchant, R. Riley, 1996, Blood.

B220- bone marrow progenitor cells from New Zealand black autoimmune mice exhibit an age-associated decline in Pre-B and B-cell generation.

B. Garvy, M. Merchant, R. Riley, 1995, Blood.

B cells in autoimmune (NZB x NZW)F1 mice show altered IgG isotype switching upon T cell-dependent antigenic stimulation in vitro.

A. Ringel, R. Riley, B. Landa, 1991, Clinical immunology and immunopathology.

Energy transfer: a general method for the study of protein-nucleic acid interactions.

R. Riley, R. Taylor, D. Weber, 1977, Archives of biochemistry and biophysics.

IFN-gamma abrogates IL-7-dependent proliferation in pre-B cells, coinciding with onset of apoptosis.

B. Garvy, R. Riley, 1994, Immunology.

Stability of DNA/anti-DNA complexes. II. Salt lability and avidity.

D. Addis, R. Riley, R. Taylor, 1980, Journal of immunology.

Soluble and membrane-bound TNF-alpha are involved in the cytotoxic activity of B cells from tumor-bearing mice against tumor targets.

E. Podack, M. Handel, J. A. Garcia-Sanz, 1994, Journal of immunology.

Impaired B lymphopoiesis in old age: a role for inflammatory B cells?

R. Riley, 2013, Immunologic research.

Cutting Edge: Senescent BALB/c Mice Exhibit Decreased Expression of λ5 Surrogate Light Chains and Reduced Development Within the Pre-B Cell Compartment

B. Blomberg, R. Riley, W. Xu, 1998, The Journal of Immunology.

Senescent BALB/c mice exhibit decreased expression of lambda5 surrogate light chains and reduced development within the pre-B cell compartment.

B. Blomberg, R. Riley, E. Sherwood, 1998, Journal of immunology.

The Antigenic Structure of Bovine Serum Albumin: T-Cell, B-Cell, And Ia Determinants

D. Benjamin, R. Riley, Lisa A. Daigle, 1983 .

The affinity threshold for antigenic triggering differs for tolerance susceptible immature precursors vs mature primary B cells.

R. Riley, N. Klinman, 1986, Journal of immunology.

Differences in antibody repertoires for (4-hydroxy-3-nitrophenyl)acetyl (NP) in splenic vs immature bone marrow precursor cells.

R. Riley, N. Klinman, 1985, Journal of Immunology.

Self-Assembling Electron-Transport Chains in Zeolites: Molecular Bilayer Rectifiers and Photodiodes

T. Mallouk, R. Riley, Edward H. Yonemoto, 1992 .

Comparison of immature B-cell populations in neonates and adults.

D. Zharhary, M. Schaefer, R. Riley, 1984, Annales d'immunologie.