Jungsoon Lee

发表

MEP-1 and a Homolog of the NURD Complex Component Mi-2 Act Together to Maintain Germline-Soma Distinctions in C. elegans

C. Mello, T. Shin, Yingdee Unhavaithaya, 2002, Cell.

Yeast-expressed recombinant SARS-CoV-2 receptor binding domain RBD203-N1 as a COVID-19 protein vaccine candidate

P. Hotez, J. Pollet, A. Bailey, 2021, bioRxiv.

Yeast-expressed recombinant SARS-CoV-2 receptor binding domain RBD203-N1 as a COVID-19 protein vaccine candidate

P. Hotez, J. Pollet, A. Bailey, 2021, Protein Expression and Purification.

Mapping Interactions with the Chaperone Network Reveals Factors that Protect Against Tau Aggregation

J. Gestwicki, Mark R. Wilson, M. Zweckstetter, 2018, Nature Structural & Molecular Biology.

Structural determinants for protein unfolding and translocation by the Hsp104 protein disaggregase

Changsoo Chang, Jungsoon Lee, Sukyeong Lee, 2017, Bioscience reports.

Overlapping and Specific Functions of the Hsp104 N Domain Define Its Role in Protein Disaggregation

C. Hryc, Changsoo Chang, Jungsoon Lee, 2017, Scientific Reports.

SARS‑CoV-2 RBD219-N1C1: A yeast-expressed SARS-CoV-2 recombinant receptor-binding domain candidate vaccine stimulates virus neutralizing antibodies and T-cell immunity in mice

P. Hotez, J. Pollet, M. Bottazzi, 2021, Human vaccines & immunotherapeutics.

SARS-CoV-2 RBD219-N1C1: A Yeast-Expressed SARS-CoV-2 Recombinant Receptor-Binding Domain Candidate Vaccine Stimulates Virus Neutralizing Antibodies and T-cell Immunity in Mice

P. Hotez, J. Pollet, M. Bottazzi, 2020, bioRxiv.

Mitochondrial Hsp90 is a ligand-activated molecular chaperone coupling ATP binding to dimer closure through a coiled-coil intermediate

A. Joachimiak, Ji-Hyun Kim, Changsoo Chang, 2016, Proceedings of the National Academy of Sciences.

Molecular chaperones: guardians of the proteome in normal and disease states

Jungsoon Lee, Sukyeong Lee, F. Tsai, 2015, F1000Research.

2.4 Å resolution crystal structure of human TRAP1NM, the Hsp90 paralog in the mitochondrial matrix.

J. Kim, Changsoo Chang, Jungsoon Lee, 2016, Acta crystallographica. Section D, Structural biology.

Receptor-binding domain recombinant protein on alum-CpG induces broad protection against SARS-CoV-2 variants of concern

P. Hotez, J. Pollet, Zhuyun Liu, 2022, Vaccine.

Process development and scale-up optimization of the SARS-CoV-2 receptor binding domain–based vaccine candidate, RBD219-N1C1

P. Hotez, M. Bottazzi, Zhuyun Liu, 2020, Applied Microbiology and Biotechnology.

Heat shock protein (Hsp) 70 is an activator of the Hsp104 motor

Ji-Hyun Kim, A. Biter, Jungsoon Lee, 2013, Proceedings of the National Academy of Sciences.

Cryo-EM Structures of the Hsp104 Protein Disaggregase Captured in the ATP Conformation

Jun Liu, Jungsoon Lee, Sukyeong Lee, 2019, Cell reports.

Process development and scale-up optimization of the SARS-CoV-2 receptor binding domain–based vaccine candidate, RBD219-N1C1

P. Hotez, M. Bottazzi, Zhuyun Liu, 2021, Applied microbiology and biotechnology.

Crystal Structure of the YcjX Stress Protein Reveals a Ras-Like GTP-Binding Protein.

Changsoo Chang, Jungsoon Lee, Sukyeong Lee, 2019, Journal of molecular biology.

Functional analysis of conserved cis- and trans-elements in the Hsp104 protein disaggregating machine.

A. Biter, Jungsoon Lee, Sukyeong Lee, 2012, Journal of structural biology.

Seroepidemiology of predominant norovirus strains circulating in Korea by using recombinant virus-like particle antigens.

D. Cheon, Jungsoon Lee, H. Jeong, 2013, Foodborne pathogens and disease.

Receptor-binding domain recombinant protein on alum-CpG induces broad protection against SARS-CoV-2 variants of concern

P. Hotez, J. Pollet, M. Bottazzi, 2021, bioRxiv.

A yeast-expressed RBD-based SARS-CoV-2 vaccine formulated with 3M-052-alum adjuvant promotes protective efficacy in non-human primates

Jennifer S. Wood, Muhammad Bilal Latif, A. Sette, 2021, Science Immunology.

Genetic modification to design a stable yeast-expressed recombinant SARS-CoV-2 receptor binding domain as a COVID-19 vaccine candidate

P. Hotez, J. Pollet, M. Bottazzi, 2020, Biochimica et Biophysica Acta (BBA) - General Subjects.

Cloning, Expression and Biophysical Characterization of a Yeast-expressed Recombinant SARS-CoV-2 Receptor Binding Domain COVID-19 Vaccine Candidate

P. Hotez, J. Pollet, M. Bottazzi, 2020, bioRxiv.

The mitochondrial HSP90 paralog TRAP1 forms an OXPHOS-regulated tetramer and is involved in mitochondrial metabolic homeostasis

D. Agard, L. Neckers, L. Jenkins, 2020, BMC Biology.

The mitochondrial HSP90 paralog TRAP1 forms an OXPHOS-regulated tetramer and is involved in mitochondrial metabolic homeostasis

D. Agard, L. Neckers, L. Jenkins, 2020, BMC Biology.

CNP-1 (ARRD-17), a novel substrate of calcineurin, is critical for modulation of egg-laying and locomotion in response to food and lysine sensation in Caenorhabditis elegans.

N. L’Etoile, C. Jee, Hyun-Ok Song, 2012, Journal of molecular biology.

Calcineurin, a calcium/calmodulin-dependent protein phosphatase, is involved in movement, fertility, egg laying, and growth in Caenorhabditis elegans.

D. H. Kim, Jiyeon Lee, S. Zannoni, 2002, Molecular biology of the cell.

CryoEM structure of Hsp104 and its mechanistic implication for protein disaggregation

Jungsoon Lee, Sukyeong Lee, F. Tsai, 2010, Proceedings of the National Academy of Sciences.

Overlapping and Specific Functions of the Hsp104 N Domain Define Its Role in Protein Disaggregation

C. Hryc, Changsoo Chang, Jungsoon Lee, 2017, Scientific Reports.

The mitochondrial HSP90 paralog TRAP1 forms an OXPHOS-regulated tetramer and is involved in maintaining mitochondrial metabolic homeostasis

L. Neckers, Gregory Segala, D. Picard, 2019, bioRxiv.

Calreticulin, a calcium-binding molecular chaperone, is required for stress response and fertility in Caenorhabditis elegans.

D. H. Kim, D. H. Kim, S. Eom, 2001, Molecular biology of the cell.