A. J. Yun

发表

A general theory of evolution based on energy efficiency: its implications for diseases.

Patrick Y Lee, Anthony J Yun, A. J. Yun, 2006, Medical hypotheses.

Integrating systems biology and medical imaging: understanding disease distribution in the lung model.

Patrick Y Lee, Anthony J Yun, Anthony N Gerber, 2006, AJR. American journal of roentgenology.

Integrating the theories of Darwin and Bernoulli: maladaptive baroreceptor network dysfunction may explain the pathogenesis of aortic aneurysms.

Patrick Y Lee, A. J. Yun, John D. Doux, 2005, Medical hypotheses.

Autonomic dysregulation as a basis of cardiovascular, endocrine, and inflammatory disturbances associated with obstructive sleep apnea and other conditions of chronic hypoxia, hypercapnia, and acidosis.

Patrick Y Lee, A. J. Yun, K. Bazar, 2004, Medical hypotheses.

Environmental discontinuity hypothesis: Buffer dysfunctions as a source of human disease.

A. J. Yun, A. Yun, 2007, Medical hypotheses.

Adventitial dysfunction: an evolutionary model for understanding atherosclerosis.

Patrick Y Lee, A. J. Yun, John D. Doux, 2005, Medical hypotheses.

When normal is not: the dilemma of interpreting laboratory averages of bioactive molecules subject to heterogeneous regulatory feedback and epigenetic mosaicism.

A. J. Yun, John D. Doux, A. Yun, 2006, Medical hypotheses.

Paradoxical strategy for treating chronic diseases where the therapeutic effect is derived from compensatory response rather than drug effect.

Patrick Y Lee, A. J. Yun, K. Bazar, 2005, Medical hypotheses.

The link between carotid artery disease and ischemic stroke may be partially attributable to autonomic dysfunction and failure of cerebrovascular autoregulation triggered by Darwinian maladaptation of the carotid baroreceptors and chemoreceptors.

A. J. Yun, John D. Doux, 2006, Medical hypotheses.

Clinical benefits of hydration and volume expansion in a wide range of illnesses may be attributable to reduction of sympatho-vagal ratio.

Patrick Y Lee, A. J. Yun, K. Bazar, 2005, Medical hypotheses.

Acute coronary syndromes and heart failure may reflect maladaptations of trauma physiology that was shaped during pre-modern evolution.

Patrick Y Lee, A. J. Yun, K. Bazar, 2004, Medical hypotheses.

Modulation of host immunity by HIV may be partly achieved through usurping host autonomic functions.

Patrick Y Lee, A. J. Yun, K. Bazar, 2004, Medical hypotheses.

Maldaptation of the link between inflammation and bone turnover may be a key determinant of osteoporosis.

Patrick Y Lee, A. J. Yun, 2004, Medical hypotheses.

Menstrual variation of autonomic balance may be a factor in exacerbations of certain diseases during the menstrual cycle.

Patrick Y Lee, A. J. Yun, K. Bazar, 2004, Medical hypotheses.

Debunking a myth: neurohormonal and vagal modulation of sleep centers, not redistribution of blood flow, may account for postprandial somnolence.

Patrick Y Lee, A. J. Yun, K. Bazar, 2004, Medical hypotheses.

Can chronic use of anti-inflammatory agents paradoxically promote chronic inflammation through compensatory host response?

Patrick Y Lee, A. J. Yun, John D. Doux, 2005, Medical hypotheses.

A new mechanism for diverticular diseases: aging-related vagal withdrawal.

Patrick Y Lee, A. J. Yun, K. Bazar, 2005, Medical hypotheses.

The smoking gun: many conditions associated with tobacco exposure may be attributable to paradoxical compensatory autonomic responses to nicotine.

Patrick Y Lee, A. J. Yun, A. Gerber, 2005, Medical hypotheses.

Sudden death among infants and adults: companion disorders of maladaptive sympathetic bias.

Patrick Y Lee, A. J. Yun, A. Yun, 2004, Medical hypotheses.

Paradoxical inflammation revisited: muraglitazar and cardiovascular risk.

Patrick Y Lee, A. J. Yun, John D. Doux, 2006, Medical hypotheses.

Peripheral arterial disease: a manifestation of evolutionary dislocation and feed-forward dysfunction.

Patrick Y Lee, A. J. Yun, John D. Doux, 2006, Medical hypotheses.

"Starve a fever and feed a cold": feeding and anorexia may be adaptive behavioral modulators of autonomic and T helper balance.

Patrick Y Lee, A. J. Yun, K. Bazar, 2005, Medical hypotheses.

Enhanced fertility after diagnostic hysterosalpingography using oil-based contrast agents may be attributable to immunomodulation.

Patrick Y Lee, A. J. Yun, A. Yun, 2004, AJR. American journal of roentgenology.

Autonomic dysfunction may be an under-recognized cause of female fertility disorders.

Patrick Y Lee, A. J. Yun, K. Bazar, 2004, Medical hypotheses.

The intellectual lineage of paradoxical pharmacology strategy.

A. J. Yun, 2005, Medical hypotheses.

Hypertrophic osteoarthropathy may be a marker of underlying sympathetic bias.

Patrick Y Lee, A. J. Yun, K. Bazar, 2004, Medical hypotheses.

Immunomodulatory function of seminal catecholamines may be an adaptation for reproduction.

Patrick Y Lee, A. J. Yun, K. Bazar, 2004, Medical hypotheses.

The incorporation of iodine in thyroid hormone may stem from its role as a prehistoric signal of ecologic opportunity: an evolutionary perspective and implications for modern diseases.

Patrick Y Lee, A. J. Yun, John D. Doux, 2005, Medical hypotheses.

Pineal attrition, loss of cognitive plasticity, and onset of puberty during the teen years: is it a modern maladaptation exposed by evolutionary displacement?

Patrick Y Lee, A. J. Yun, K. Bazar, 2004, Medical hypotheses.

Can thromboembolism be the result, rather than the inciting cause, of acute vascular events such as stroke, pulmonary embolism, mesenteric ischemia, and venous thrombosis?: a maladaptation of the prehistoric trauma response.

Patrick Y Lee, A. J. Yun, K. Bazar, 2005, Medical hypotheses.

Brewing controversies: Darwinian perspective on the adaptive and maladaptive effects of caffeine and ethanol as dietary autonomic modulators.

A. J. Yun, John D. Doux, S. Daniel, 2007, Medical hypotheses.

Iodine in the Ecosystem: An Overview

A. J. Yun, John D. Doux, A. Yun, 2009 .

Osteoarthritis: an example of phenoptosis through autonomic dysfunction?

Patrick Y Lee, A. J. Yun, John D. Doux, 2006, Medical hypotheses.

Temporal variation of autonomic balance and diseases during circadian, seasonal, reproductive, and lifespan cycles.

Patrick Y Lee, A. J. Yun, K. Bazar, 2004, Medical hypotheses.

Obesity and ADHD may represent different manifestations of a common environmental oversampling syndrome: a model for revealing mechanistic overlap among cognitive, metabolic, and inflammatory disorders.

Patrick Y Lee, A. J. Yun, John D. Doux, 2006, Medical hypotheses.

Contrast nephropathy may be partly mediated by autonomic dysfunction: renal failure considered as a modern maladaptation of the prehistoric trauma response.

Patrick Y Lee, A. J. Yun, John D. Doux, 2006, Medical hypotheses.

Negative pressure ventilation via diaphragmatic pacing: a potential gateway for treating systemic dysfunctions

Patrick Y Lee, A. J. Yun, John D. Doux, 2007, Expert review of medical devices.

Stress dysfunctions as a unifying paradigm for illness: repairing relationships instead of individuals as a new gateway for medicine.

A. J. Yun, John D. Doux, A. Yun, 2007, Medical hypotheses.

Efficient inefficiency: biochemical "junk" may represent molecular bridesmaids awaiting emergent function as a buffer against environmental fluctuation.

Patrick Y Lee, A. J. Yun, John D. Doux, 2006, Medical hypotheses.

Sympathetic and T helper (Th)2 bias may ameliorate uterine fibroids, independent of sex steroids.

A. J. Yun, S. Daniel, A. Yun, 2005, Medical hypotheses.

Strengthening national nutrition research: rationale and options for a new coordinated federal research effort and authority

D. Mozaffarian, J. Loscalzo, A. Parekh, 2020, The American journal of clinical nutrition.

Is atherosclerosis a neurogenic phenomenon?

Patrick Y Lee, A. J. Yun, John D. Doux, 2007, Medical hypotheses.

The dynamic range of biologic functions and variation of many environmental cues may be declining in the modern age: implications for diseases and therapeutics.

Patrick Y Lee, A. J. Yun, A. Gerber, 2005, Medical hypotheses.

The hegemony of empiricism: the opportunity for theoretical science in medicine.

A. J. Yun, 2008, Medical hypotheses.

Many diseases may reflect dysfunctions of autonomic balance attributable to evolutionary displacement.

Patrick Y Lee, A. J. Yun, K. Bazar, 2004, Medical hypotheses.

Modulation of autonomic balance by tumors and viruses.

Patrick Y Lee, A. J. Yun, K. Bazar, 2004, Medical hypotheses.

A new wrinkle: skin manifestations of aging may relate to autonomic dysfunction.

A. J. Yun, John D. Doux, K. Bazar, 2006, Medical Hypotheses.

Conditions of aging as manifestations of sympathetic bias unmasked by loss of parasympathetic function.

Patrick Y Lee, A. J. Yun, K. Bazar, 2004, Medical hypotheses.

Are we eating more than we think? Illegitimate signaling and xenohormesis as participants in the pathogenesis of obesity.

Patrick Y Lee, A. J. Yun, John D. Doux, 2006, Medical hypotheses.

The link between T helper balance and lymphoproliferative disease.

Patrick Y Lee, A. J. Yun, A. Yun, 2005, Medical hypotheses.

A paradigm for viewing biologic systems as scale-free networks based on energy efficiency: implications for present therapies and the future of evolution.

Patrick Y Lee, A. J. Yun, John D. Doux, 2006, Medical hypotheses.

Unhappy meal: how our need to detect stress may have shaped our preferences for taste.

A. J. Yun, John D. Doux, A. Yun, 2007, Medical hypotheses.

Opening the floodgates: benign prostatic hyperplasia may represent another disease in the compendium of ailments caused by the global sympathetic bias that emerges with aging.

A. J. Yun, John D. Doux, 2006, Medical hypotheses.